Comparison of the anti-influenza virus activity of cyclopentane derivatives with oseltamivir and zanamivir in vivo

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 12, 2005, Pages 4071-4077

  Chand, Pooran ^a   Bantia, Shanta ^a   Kotian, Pravin L ^a   El Kattan, Yahya ^a   Lin, Tsu Hsing ^a   Babu, Yarlagadda S ^a  

^a BIOCRYST PHARMACEUTICALS INC   (United States)

Author keywords

Cyclopentane derivatives; In vivo activity; Neuraminidase inhibitors

Indexed keywords

3 (1 ACETAMIDO 2 ETHYLBUTYL) 4 GUANIDINOCYCLOPENTANECARBOXYLIC ACID; 3 (1 ACETAMIDO 2 PROPYLPENTYL) 4 GUANIDINO 2 HYDROXYCYCLOPENTANECARBOXYLIC ACID; 3 (1 ACETAMIDO 2 PROPYLPENTYL) 4 GUANIDINOCYCLOPENTANECARBOXYLIC ACID; 3 [1 (ACETYLAMINO) 2 (PROPYLPENTYL)] 4 [[AMINO(IMINO)METHYL]AMINO] 2 HYDROXYCYCLOPENTANE CARBOXYLIC ACID; 3 [1 (ACETYLAMINO) 2 (PROPYLPENTYL)] 4 [[AMINO(IMINO)METHYL]AMINO] CYCLOPENTANE CARBOXYLIC ACID; CYCLOPENTENE DERIVATIVE; OSELTAMIVIR; PERAMIVIR; UNCLASSIFIED DRUG; ZANAMIVIR;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; IN VIVO STUDY; INFLUENZA; INFLUENZA VIRUS; NONHUMAN; PROTECTION;

ACETAMIDES; ADMINISTRATION, INTRANASAL; ADMINISTRATION, ORAL; ANIMALS; ANTIVIRAL AGENTS; CYCLOPENTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANIDINES; MICE; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; OSELTAMIVIR; PYRANS; SIALIC ACIDS; STRUCTURE-ACTIVITY RELATIONSHIP; SURVIVAL RATE; TREATMENT OUTCOME; ZANAMIVIR;

INFLUENZA VIRUS;

EID: 19444375732     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.03.048     Document Type: Article

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