-
1
-
-
0036559186
-
Gli and hedgehog in cancer: Tumours, embryos and stem cells
-
Ruiz i Altaba, A., P. Sánchez, and N. Dahmane. 2002. Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat. Rev. Cancer 2: 361-372.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 361-372
-
-
Ruiz I Altaba, A.1
Sánchez N Dahmane, P.2
-
2
-
-
0033712944
-
Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte
-
Outram, S. V., A. Varas, C. V. Pepicelli, and T. Crompton. 2000. Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte. Immunity 13: 187-197.
-
(2000)
Immunity
, vol.13
, pp. 187-197
-
-
Outram, S.V.1
Varas, A.2
Pepicelli, C.V.3
Crompton, T.4
-
3
-
-
0842343439
-
Reduced Thymocyte Development in Sonic Hedgehog Knockout Embryos
-
Shah, D. K., A. L. Hager-Theodorides, S. V. Outram, S. E. Ross, A. Varas, and T. Crompton. 2004. Reduced thymocyte development in sonic hedgehog knockout embryos. J. Immunol. 172: 2296-2306. (Pubitemid 38182377)
-
(2004)
Journal of Immunology
, vol.172
, Issue.4
, pp. 2296-2306
-
-
Shah, D.K.1
Hager-Theodorides, A.L.2
Outram, S.V.3
Ross, S.E.4
Varas, A.5
Crompton, T.6
-
4
-
-
23744495499
-
- double-negative thymocytes
-
DOI 10.1182/blood-2005-03-0998
-
Hager-Theodorides, A. L., J. T. Dessens, S. V. Outram, and T. Crompton. 2005. The transcription factor Gli3 regulates differentiation of fetal CD4- CD8- double-negative thymocytes. Blood 106: 1296-1304. (Pubitemid 41129593)
-
(2005)
Blood
, vol.106
, Issue.4
, pp. 1296-1304
-
-
Hager-Theodorides, A.L.1
Dessens, J.T.2
Outram, S.V.3
Crompton, T.4
-
5
-
-
33645095936
-
Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus
-
El Andaloussi, A., S. Graves, F. Meng, M. Mandal, M. Mashayekhi, and I. Aifantis. 2006. Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus. Nat. Immunol. 7: 418-426.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 418-426
-
-
El Andaloussi, A.1
Graves, S.2
Meng, F.3
Mandal, M.4
Mashayekhi, M.5
Aifantis, I.6
-
6
-
-
34548834154
-
The Hedgehog receptor Patched controls lymphoid lineage commitment
-
DOI 10.1182/blood-2007-02-075648
-
Uhmann, A., K. Dittmann, F. Nitzki, R. Dressel, M. Koleva, A. Frommhold, A. Zibat, C. Binder, I. Adham, M. Nitsche, et al. 2007. The Hedgehog receptor Patched controls lymphoid lineage commitment. Blood 110: 1814-1823. (Pubitemid 47443892)
-
(2007)
Blood
, vol.110
, Issue.6
, pp. 1814-1823
-
-
Uhmann, A.1
Dittmann, K.2
Nitzki, F.3
Dressel, R.4
Koleva, M.5
Frommhold, A.6
Zibat, A.7
Binder, C.8
Adham, I.9
Nitsche, M.10
Heller, T.11
Armstrong, V.12
Schulz-Schaeffer, W.13
Wienands, J.14
Hahn, H.15
-
7
-
-
70349229823
-
The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms
-
Siggins, S. L., N. Y. Nguyen, M. P. McCormack, S. Vasudevan, R. Villani, S. M. Jane, B. J. Wainwright, and D. J. Curtis. 2009. The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms. Blood 114: 995-1004.
-
(2009)
Blood
, vol.114
, pp. 995-1004
-
-
Siggins, S.L.1
Nguyen, N.Y.2
McCormack, M.P.3
Vasudevan, S.4
Villani, R.5
Jane, S.M.6
Wainwright, B.J.7
Curtis, D.J.8
-
8
-
-
34247332974
-
Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation
-
DOI 10.1182/blood-2006-07-037655
-
Rowbotham, N. J., A. L. Hager-Theodorides, M. Cebecauer, D. K. Shah, E. Drakopoulou, J. Dyson, S. V. Outram, and T. Crompton. 2007. Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation. Blood 109: 3757-3766. (Pubitemid 46641726)
-
(2007)
Blood
, vol.109
, Issue.9
, pp. 3757-3766
-
-
Rowbotham, N.J.1
Hager-Theodorides, A.L.2
Cebecauer, M.3
Shah, D.K.4
Drakopoulou, E.5
Dyson, J.6
Outram, S.V.7
Crompton, T.8
-
9
-
-
70349235509
-
The Gli3 transcription factor expressed in the thymus stroma controls thymocyte negative selection via Hedgehog-dependent and -independent mechanisms
-
Hager-Theodorides, A. L., A. L. Furmanski, S. E. Ross, S. V. Outram, N. J. Rowbotham, and T. Crompton. 2009. The Gli3 transcription factor expressed in the thymus stroma controls thymocyte negative selection via Hedgehog-dependent and -independent mechanisms. J. Immunol. 183: 3023-3032.
-
(2009)
J. Immunol.
, vol.183
, pp. 3023-3032
-
-
Hager-Theodorides, A.L.1
Furmanski, A.L.2
Ross, S.E.3
Outram, S.V.4
Rowbotham, N.J.5
Crompton, T.6
-
10
-
-
34548817270
-
Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues
-
DOI 10.1152/physiolgenomics.00019.2007
-
Hameyer, D., A. Loonstra, L. Eshkind, S. Schmitt, C. Antunes, A. Groen, E. Bindels, J. Jonkers, P. Krimpenfort, R. Meuwissen, et al. 2007. Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues. Physiol. Genomics 31: 32-41. (Pubitemid 47443846)
-
(2007)
Physiological Genomics
, vol.31
, Issue.1
, pp. 32-41
-
-
Hameyer, D.1
Loonstra, A.2
Eshkind, L.3
Schmitt, S.4
Antunes, C.5
Groen, A.6
Bindels, E.7
Jonkers, J.8
Krimpenfort, P.9
Meuwissen, R.10
Rijswijk, L.11
Bex, A.12
Berns, A.13
Bockamp, E.14
-
11
-
-
5844299536
-
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development
-
Wolfer, A., T. Bakker, A. Wilson, M. Nicolas, V. Ioannidis, D. R. Littman, P. P. Lee, C. B. Wilson, W. Held, H. R. MacDonald, and F. Radtke. 2001. Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. Nat. Immunol. 2: 235-241.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 235-241
-
-
Wolfer, A.1
Bakker, T.2
Wilson, A.3
Nicolas, M.4
Ioannidis, V.5
Littman, D.R.6
Lee, P.P.7
Wilson, C.B.8
Held, W.9
MacDonald, H.R.10
Radtke, F.11
-
12
-
-
66749083231
-
Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts
-
Zibat, A., A. Uhmann, F. Nitzki, M. Wijgerde, A. Frommhold, T. Heller, V. Armstrong, L. Wojnowski, L. Quintanilla-Martinez, J. Reifenberger, et al. 2009. Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts. Carcinogenesis 30: 918-926.
-
(2009)
Carcinogenesis
, vol.30
, pp. 918-926
-
-
Zibat, A.1
Uhmann, A.2
Nitzki, F.3
Wijgerde, M.4
Frommhold, A.5
Heller, T.6
Armstrong, V.7
Wojnowski, L.8
Quintanilla-Martinez, L.9
Reifenberger, J.10
-
13
-
-
50949102041
-
Peripheral T cells are the therapeutic targets of glucocorticoids in experimental autoimmune encephalomyelitis
-
Wüst, S., J. van den Brandt, D. Tischner, A. Kleiman, J. P. Tuckermann, R. Gold, F. Lühder, and H. M. Reichardt. 2008. Peripheral T cells are the therapeutic targets of glucocorticoids in experimental autoimmune encephalomyelitis. J. Immunol. 180: 8434-8443.
-
(2008)
J. Immunol.
, vol.180
, pp. 8434-8443
-
-
Wüst, S.1
Van Den Brandt, J.2
Tischner, D.3
Kleiman, A.4
Tuckermann, J.P.5
Gold, R.6
Lühder, F.7
Reichardt, H.M.8
-
14
-
-
34248206597
-
Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy
-
Tuckermann, J. P., A. Kleiman, R. Moriggl, R. Spanbroek, A. Neumann, A. Illing, B. E. Clausen, B. Stride, I. Förster, A. J. Habenicht, et al. 2007. Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy. J. Clin. Invest. 117: 1381-1390.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1381-1390
-
-
Tuckermann, J.P.1
Kleiman, A.2
Moriggl, R.3
Spanbroek, R.4
Neumann, A.5
Illing, A.6
Clausen, B.E.7
Stride, B.8
Förster, I.9
Habenicht, A.J.10
-
15
-
-
2942731430
-
Inhibition of Notch signaling biases rat thymocyte development towards the NK cell lineage
-
van den Brandt, J., K. Voss, M. Schott, T. Hünig, M. S. Wolfe, and H. M. Reichardt. 2004. Inhibition of Notch signaling biases rat thymocyte development towards the NK cell lineage. Eur. J. Immunol. 34: 1405-1413.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1405-1413
-
-
Van Den Brandt, J.1
Voss, K.2
Schott, M.3
Hünig, T.4
Wolfe, M.S.5
Reichardt, H.M.6
-
16
-
-
74249114655
-
Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis
-
Kenins, L., J. W. Gill, G. A. Holländer, and A. Wodnar-Filipowicz. 2010. Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis. Eur. J. Immunol. 40: 81-90.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 81-90
-
-
Kenins, L.1
Gill, J.W.2
Holländer, G.A.3
Wodnar-Filipowicz, A.4
-
17
-
-
1542267685
-
Resistance of single-positive thymocytes to glucocorticoid-induced apoptosis is mediated by CD28 signaling
-
van den Brandt, J., D. Wang, and H. M. Reichardt. 2004. Resistance of single-positive thymocytes to glucocorticoid-induced apoptosis is mediated by CD28 signaling. Mol. Endocrinol. 18: 687-695.
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 687-695
-
-
Van Den Brandt, J.1
Wang, D.2
Reichardt, H.M.3
-
18
-
-
22144465538
-
Glucocorticoids inhibit activation-induced cell death (AICD) via direct DNA-dependent repression of the CD95 ligand gene by a glucocorticoid receptor dimer
-
Baumann, S., A. Dostert, N. Novac, A. Bauer, W. Schmid, S. C. Fas, A. Krueger, T. Heinzel, S. Kirchhoff, G. Schütz, and P. H. Krammer. 2005. Glucocorticoids inhibit activation-induced cell death (AICD) via direct DNA-dependent repression of the CD95 ligand gene by a glucocorticoid receptor dimer. Blood 106: 617-625.
-
(2005)
Blood
, vol.106
, pp. 617-625
-
-
Baumann, S.1
Dostert, A.2
Novac, N.3
Bauer, A.4
Schmid, W.5
Fas, S.C.6
Krueger, A.7
Heinzel, T.8
Kirchhoff, S.9
Schütz, G.10
Krammer, P.H.11
-
19
-
-
2942516896
-
Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages
-
Porritt, H. E., L. L. Rumfelt, S. Tabrizifard, T. M. Schmitt, J. C. Zúñiga-Pflücker, and H. T. Petrie. 2004. Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity 20: 735-745.
-
(2004)
Immunity
, vol.20
, pp. 735-745
-
-
Porritt, H.E.1
Rumfelt, L.L.2
Tabrizifard, S.3
Schmitt, T.M.4
Zúñiga-Pflücker, J.C.5
Petrie, H.T.6
-
20
-
-
43549105168
-
The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell development
-
Benz, C., V. C. Martins, F. Radtke, and C. C. Bleul. 2008. The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell development. J. Exp. Med. 205: 1187-1199.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1187-1199
-
-
Benz, C.1
Martins, V.C.2
Radtke, F.3
Bleul, C.C.4
-
21
-
-
33644842282
-
From stem cell to T cell: One route or many?
-
Bhandoola, A., and A. Sambandam. 2006. From stem cell to T cell: one route or many? Nat. Rev. Immunol. 6: 117-126.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 117-126
-
-
Bhandoola, A.1
Sambandam, A.2
-
22
-
-
70449517408
-
Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse
-
Finetti, F., S. R. Paccani, M. G. Riparbelli, E. Giacomello, G. Perinetti, G. J. Pazour, J. L. Rosenbaum, and C. T. Baldari. 2009. Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse. Nat. Cell Biol. 11: 1332-1339.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1332-1339
-
-
Finetti, F.1
Paccani, S.R.2
Riparbelli, M.G.3
Giacomello, E.4
Perinetti, G.5
Pazour, G.J.6
Rosenbaum, J.L.7
Baldari, C.T.8
-
23
-
-
69949136621
-
Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis
-
Wong, S. Y., A. D. Seol, P. L. So, A. N. Ermilov, C. K. Bichakjian, E. H. Epstein, Jr., A. A. Dlugosz, and J. F. Reiter. 2009. Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat. Med. 15: 1055-1061.
-
(2009)
Nat. Med.
, vol.15
, pp. 1055-1061
-
-
Wong, S.Y.1
Seol, A.D.2
So, P.L.3
Ermilov, A.N.4
Bichakjian, C.K.5
Epstein Jr., E.H.6
Dlugosz, A.A.7
Reiter, J.F.8
-
24
-
-
69949166247
-
Dual and opposing roles of primary cilia in medulloblastoma development
-
Han, Y. G., H. J. Kim, A. A. Dlugosz, D. W. Ellison, R. J. Gilbertson, and A. Alvarez-Buylla. 2009. Dual and opposing roles of primary cilia in medulloblastoma development. Nat. Med. 15: 1062-1065.
-
(2009)
Nat. Med.
, vol.15
, pp. 1062-1065
-
-
Han, Y.G.1
Kim, H.J.2
Dlugosz, A.A.3
Ellison, D.W.4
Gilbertson, R.J.5
Alvarez-Buylla, A.6
-
25
-
-
2942700206
-
Reduction in the developmental potential of intrathymic T cell progenitors with age
-
Min, H., E. Montecino-Rodriguez, and K. Dorshkind. 2004. Reduction in the developmental potential of intrathymic T cell progenitors with age. J. Immunol. 173: 245-250. (Pubitemid 38797348)
-
(2004)
Journal of Immunology
, vol.173
, Issue.1
, pp. 245-250
-
-
Min, H.1
Montecino-Rodriguez, E.2
Dorshkind, K.3
-
26
-
-
61849118560
-
Progenitor migration to the thymus and T cell lineage commitment
-
Sambandam, A., J. J. Bell, B. A. Schwarz, V. P. Zediak, A. W. Chi, D. A. Zlotoff, S. L. Krishnamoorthy, J. M. Burg, and A. Bhandoola. 2008. Progenitor migration to the thymus and T cell lineage commitment. Immunol. Res. 42: 65-74.
-
(2008)
Immunol. Res.
, vol.42
, pp. 65-74
-
-
Sambandam, A.1
Bell, J.J.2
Schwarz, B.A.3
Zediak, V.P.4
Chi, A.W.5
Zlotoff, D.A.6
Krishnamoorthy, S.L.7
Burg, J.M.8
Bhandoola, A.9
-
27
-
-
66049102512
-
Hedgehog signaling is dispensable for adult hematopoietic stem cell function
-
Gao, J., S. Graves, U. Koch, S. Liu, V. Jankovic, S. Buonamici, A. El Andaloussi, S. D. Nimer, B. L. Kee, R. Taichman, et al. 2009. Hedgehog signaling is dispensable for adult hematopoietic stem cell function. Cell Stem Cell 4: 548-558.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 548-558
-
-
Gao, J.1
Graves, S.2
Koch, U.3
Liu, S.4
Jankovic, V.5
Buonamici, S.6
El Andaloussi, A.7
Nimer, S.D.8
Kee, B.L.9
Taichman, R.10
-
28
-
-
4143142328
-
Dependence receptors: Between life and death
-
Mehlen, P., and C. Thibert. 2004. Dependence receptors: between life and death. Cell. Mol. Life Sci. 61: 1854-1866.
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 1854-1866
-
-
Mehlen, P.1
Thibert, C.2
-
29
-
-
67349287806
-
The Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complex
-
Mille, F., C. Thibert, J. Fombonne, N. Rama, C. Guix, H. Hayashi, V. Corset, J. C. Reed, and P. Mehlen. 2009. The Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complex. Nat. Cell Biol. 11: 739-746.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 739-746
-
-
Mille, F.1
Thibert, C.2
Fombonne, J.3
Rama, N.4
Guix, C.5
Hayashi, H.6
Corset, V.7
Reed, J.C.8
Mehlen, P.9
-
30
-
-
77951932085
-
Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways
-
Chinchilla, P., L. Xiao, M. G. Kazanietz, and N. A. Riobo. 2010. Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways. Cell Cycle 9: 570-579.
-
(2010)
Cell Cycle
, vol.9
, pp. 570-579
-
-
Chinchilla, P.1
Xiao, L.2
Kazanietz, M.G.3
Riobo, N.A.4
|