Directed adenovirus evolution using engineered mutator viral polymerases

Nucleic Acids Research

Volumn 39, Issue 5, 2011, Pages

  Uil, Taco G ^a   Vellinga, Jort ^a,b   De Vrij, Jeroen ^a,c   Van Den Hengel, Sanne K ^a   Rabelink, Martijn J W E ^a   Cramer, Steve J ^a   Eekels, Julia J M ^a,d   Ariyurek, Yavuz ^a   Van Galen, Michiel ^a   Hoeben, Rob C ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CRUCELL HOLLAND BV   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; EXONUCLEASE; LENTIVIRUS VECTOR; MUTATOR ADENOVIRUS POLYMERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENOVIRUS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; GENETIC VARIABILITY; HUMAN; HUMAN CELL; LENTIVIRINAE; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN MOTIF; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SEQUENCE HOMOLOGY; VIRUS REPLICATION;

ADENOVIRIDAE; ADENOVIRUS E3 PROTEINS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CELL LINE; CELL LINE, TUMOR; DIRECTED MOLECULAR EVOLUTION; DNA-DIRECTED DNA POLYMERASE; GENETIC VECTORS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; ONCOLYTIC VIRUSES; RNA SPLICING; VIRAL PROTEINS; VIRUS REPLICATION;

ADENOVIRIDAE;

EID: 79953158641     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq1258     Document Type: Article

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