메뉴 건너뛰기




Volumn 6, Issue 3, 2011, Pages

Functional role of kallikrein 6 in regulating immune cell survival

Author keywords

[No Author keywords available]

Indexed keywords

KALLIKREIN 6; PROTEIN BCL 2; PROTEINASE ACTIVATED RECEPTOR 1; RECOMBINANT ENZYME; KALLIKREIN; KLK6 PROTEIN, HUMAN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

EID: 79953127601     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018376     Document Type: Article
Times cited : (38)

References (63)
  • 2
    • 10644260335 scopus 로고    scopus 로고
    • Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease
    • Christophi GP, Isackson PJ, Blaber SI, Blaber M, Rodriguez M, et al. (2004) Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease. J Neurochem 91: 1439-1449.
    • (2004) J Neurochem , vol.91 , pp. 1439-1449
    • Christophi, G.P.1    Isackson, P.J.2    Blaber, S.I.3    Blaber, M.4    Rodriguez, M.5
  • 4
    • 47549115421 scopus 로고    scopus 로고
    • Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration
    • Scarisbrick IA, Linbo R, Vandell AG, Keegan M, Blaber SI, et al. (2008) Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration. Biol Chem 389: 739-745.
    • (2008) Biol Chem , vol.389 , pp. 739-745
    • Scarisbrick, I.A.1    Linbo, R.2    Vandell, A.G.3    Keegan, M.4    Blaber, S.I.5
  • 5
    • 4644286907 scopus 로고    scopus 로고
    • Targeting kallikrein 6-proteolysis attenuates CNS inflammatory disease
    • Blaber SI, Ciric B, Christophi GP, Bernett MJ, Blaber M, et al. (2004) Targeting kallikrein 6-proteolysis attenuates CNS inflammatory disease. FASEB J 19: 920-922.
    • (2004) FASEB J , vol.19 , pp. 920-922
    • Blaber, S.I.1    Ciric, B.2    Christophi, G.P.3    Bernett, M.J.4    Blaber, M.5
  • 6
    • 0037025309 scopus 로고    scopus 로고
    • Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system
    • Bernett MJ, Blaber SI, Scarisbrick IA, Dhanarajan P, Thompson SM, et al. (2002) Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system. J Biol Chem 277: 24562-24570.
    • (2002) J Biol Chem , vol.277 , pp. 24562-24570
    • Bernett, M.J.1    Blaber, S.I.2    Scarisbrick, I.A.3    Dhanarajan, P.4    Thompson, S.M.5
  • 8
    • 33645634897 scopus 로고    scopus 로고
    • Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects
    • Angelo PF, Lima AR, Alves FM, Blaber SI, Scarisbrick IA, et al. (2006) Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects. J Biol Chem 281: 3116-3126.
    • (2006) J Biol Chem , vol.281 , pp. 3116-3126
    • Angelo, P.F.1    Lima, A.R.2    Alves, F.M.3    Blaber, S.I.4    Scarisbrick, I.A.5
  • 10
    • 33745664539 scopus 로고    scopus 로고
    • Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs)
    • Oikonomopoulou K, Hansen KK, Saifeddine M, Vergnolle N, Tea I, et al. (2006) Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs). Biol Chem 387: 817-824.
    • (2006) Biol Chem , vol.387 , pp. 817-824
    • Oikonomopoulou, K.1    Hansen, K.K.2    Saifeddine, M.3    Vergnolle, N.4    Tea, I.5
  • 11
    • 53749092612 scopus 로고    scopus 로고
    • Protease Activated Receptor Dependent and Independent Signaling by Kallikreins 1 and 6 in CNS Neuron and Astroglial Cell Lines
    • Vandell AG, Larson N, Laxmikanthan G, Panos M, Blaber SI, et al. (2008) Protease Activated Receptor Dependent and Independent Signaling by Kallikreins 1 and 6 in CNS Neuron and Astroglial Cell Lines. J Neurochem 107: 855-870.
    • (2008) J Neurochem , vol.107 , pp. 855-870
    • Vandell, A.G.1    Larson, N.2    Laxmikanthan, G.3    Panos, M.4    Blaber, S.I.5
  • 12
    • 45949100430 scopus 로고    scopus 로고
    • Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity
    • Shpacovitch V, Feld M, Hollenberg MD, Luger TA, Steinhoff M, (2008) Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity. J Leukoc Biol 83: 1309-1322.
    • (2008) J Leukoc Biol , vol.83 , pp. 1309-1322
    • Shpacovitch, V.1    Feld, M.2    Hollenberg, M.D.3    Luger, T.A.4    Steinhoff, M.5
  • 13
    • 0037960323 scopus 로고    scopus 로고
    • Tryptase activates peripheral blood mononuclear cells causing synthesis and release of TNF-a, IL-6 and IL-1B: possible relevance to multiple sclerosis
    • Malamud V, Vaaknin A, Abramsky O, Mor M, Burgess LE, et al. (2003) Tryptase activates peripheral blood mononuclear cells causing synthesis and release of TNF-a, IL-6 and IL-1B: possible relevance to multiple sclerosis. J Neuroimmunology 138: 115-122.
    • (2003) J Neuroimmunology , vol.138 , pp. 115-122
    • Malamud, V.1    Vaaknin, A.2    Abramsky, O.3    Mor, M.4    Burgess, L.E.5
  • 14
    • 0141816690 scopus 로고    scopus 로고
    • Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells
    • Colongnato R, Slupsky JR, Jendrach M, Burysek L, Syrovets T, et al. (2003) Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells. Blood 102: 2645-2652.
    • (2003) Blood , vol.102 , pp. 2645-2652
    • Colongnato, R.1    Slupsky, J.R.2    Jendrach, M.3    Burysek, L.4    Syrovets, T.5
  • 15
    • 0038582714 scopus 로고    scopus 로고
    • Protease-activated receptor-2 signaling triggers dendritic cell development
    • Fields RC, Schoenecker JG, Hart JP, Hoffman MR, Pizzo SV, et al. (2003) Protease-activated receptor-2 signaling triggers dendritic cell development. Am J Path 162: 1817-1822.
    • (2003) Am J Path , vol.162 , pp. 1817-1822
    • Fields, R.C.1    Schoenecker, J.G.2    Hart, J.P.3    Hoffman, M.R.4    Pizzo, S.V.5
  • 16
    • 33746449323 scopus 로고    scopus 로고
    • Induction of IL-6 release from monocytes by serine proteinases and its potential mechanisms
    • Li T, Want H, He S, (2006) Induction of IL-6 release from monocytes by serine proteinases and its potential mechanisms. Scand J Immunol 64: 10-16.
    • (2006) Scand J Immunol , vol.64 , pp. 10-16
    • Li, T.1    Want, H.2    He, S.3
  • 17
    • 0028244420 scopus 로고
    • Protease-dependent T cell activation: ligation of effector cell protease receptor-1 (EPR-1) stimulates lymphocyte proliferation
    • Altieri DC, Stamnes SJ, (1994) Protease-dependent T cell activation: ligation of effector cell protease receptor-1 (EPR-1) stimulates lymphocyte proliferation. Cell Immunol 155: 371-383.
    • (1994) Cell Immunol , vol.155 , pp. 371-383
    • Altieri, D.C.1    Stamnes, S.J.2
  • 18
    • 79953130546 scopus 로고    scopus 로고
    • Protease Activated Receptor-1 down-regulates the murine inflammatory and humoral response to Helicobacter pylori
    • Wee JL, Chionh YT, Ng GZ, Harbour SN, Allison C, et al. (2009) Protease Activated Receptor-1 down-regulates the murine inflammatory and humoral response to Helicobacter pylori. Gastroenterology.
    • (2009) Gastroenterology
    • Wee, J.L.1    Chionh, Y.T.2    Ng, G.Z.3    Harbour, S.N.4    Allison, C.5
  • 19
    • 85047689926 scopus 로고    scopus 로고
    • A role for proteinase-activated receptor-1 in inflammatory bowel diseases
    • Vergnolle N, Cellars L, Mencarelli A, Rizzo G, Swaminathan S, et al. (2004) A role for proteinase-activated receptor-1 in inflammatory bowel diseases. J Clin Invest 114: 1444-1456.
    • (2004) J Clin Invest , vol.114 , pp. 1444-1456
    • Vergnolle, N.1    Cellars, L.2    Mencarelli, A.3    Rizzo, G.4    Swaminathan, S.5
  • 20
    • 0034614895 scopus 로고    scopus 로고
    • Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis
    • Cunningham MA, Rondeau E, Chen X, Coughlin SR, Holdsworth SR, et al. (2000) Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis. J Exp Med 191: 455-462.
    • (2000) J Exp Med , vol.191 , pp. 455-462
    • Cunningham, M.A.1    Rondeau, E.2    Chen, X.3    Coughlin, S.R.4    Holdsworth, S.R.5
  • 21
    • 17244377342 scopus 로고    scopus 로고
    • Reduction of arthritis severity in protease-activated receptor-deficient mice
    • Yang YH, Hall P, Little CB, Fosang AJ, Milenkovski G, et al. (2005) Reduction of arthritis severity in protease-activated receptor-deficient mice. Arthritis Rheum 52: 1325-1332.
    • (2005) Arthritis Rheum , vol.52 , pp. 1325-1332
    • Yang, Y.H.1    Hall, P.2    Little, C.B.3    Fosang, A.J.4    Milenkovski, G.5
  • 22
    • 70249093313 scopus 로고    scopus 로고
    • Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2
    • Kouzaki H, O'Grady SM, Lawrence CB, Kita H, (2009) Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2. J Immunol 183: 1427-1434.
    • (2009) J Immunol , vol.183 , pp. 1427-1434
    • Kouzaki, H.1    O'Grady, S.M.2    Lawrence, C.B.3    Kita, H.4
  • 24
    • 0036166557 scopus 로고    scopus 로고
    • Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear
    • Kawagoe J, Takizawa T, Matsumoto J, Tamiya M, Meek SE, et al. (2002) Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear. Jpn J Pharmacol 88: 77-84.
    • (2002) Jpn J Pharmacol , vol.88 , pp. 77-84
    • Kawagoe, J.1    Takizawa, T.2    Matsumoto, J.3    Tamiya, M.4    Meek, S.E.5
  • 25
    • 33344473933 scopus 로고    scopus 로고
    • Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis
    • Noorbakhsh F, Tsutsui S, Vergnolle N, Boven LA, Shariat N, et al. (2006) Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis. J Exp Med 203: 425-435.
    • (2006) J Exp Med , vol.203 , pp. 425-435
    • Noorbakhsh, F.1    Tsutsui, S.2    Vergnolle, N.3    Boven, L.A.4    Shariat, N.5
  • 26
    • 13944276781 scopus 로고    scopus 로고
    • 1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding
    • Laxmikanthan G, Blaber SI, Bernett MJ, Scarisbrick IA, Juliano MA, et al. (2005) 1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding. Proteins 58: 802-814.
    • (2005) Proteins , vol.58 , pp. 802-814
    • Laxmikanthan, G.1    Blaber, S.I.2    Bernett, M.J.3    Scarisbrick, I.A.4    Juliano, M.A.5
  • 27
    • 0029838236 scopus 로고    scopus 로고
    • High level of circulating human tissue kallikrein induces hypotension in a transgenic mouse model
    • Song Q, Chao J, Chao L, (1996) High level of circulating human tissue kallikrein induces hypotension in a transgenic mouse model. Clin Exp Hypertens 18: 975-993.
    • (1996) Clin Exp Hypertens , vol.18 , pp. 975-993
    • Song, Q.1    Chao, J.2    Chao, L.3
  • 28
    • 0034543474 scopus 로고    scopus 로고
    • Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma
    • Diamandis EP, Yousef GM, Soosaipillai AR, Bunting P, (2000) Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma. Clin Biochem 33: 579-583.
    • (2000) Clin Biochem , vol.33 , pp. 579-583
    • Diamandis, E.P.1    Yousef, G.M.2    Soosaipillai, A.R.3    Bunting, P.4
  • 29
    • 0036017352 scopus 로고    scopus 로고
    • Decreased concentration of human kallikrein 6 in brain extracts of Alzheimer's disease patients
    • Zarghooni M, Soosaipillai A, Grass L, Scorilas A, Mirazimi N, et al. (2002) Decreased concentration of human kallikrein 6 in brain extracts of Alzheimer's disease patients. Clinical Biochemistry 35: 225-231.
    • (2002) Clinical Biochemistry , vol.35 , pp. 225-231
    • Zarghooni, M.1    Soosaipillai, A.2    Grass, L.3    Scorilas, A.4    Mirazimi, N.5
  • 30
    • 3543150203 scopus 로고    scopus 로고
    • Human tissue kallikreins: physiologic roles and applications in cancer
    • Borgono CA, Miacovos MP, Diamandis EP, (2004) Human tissue kallikreins: physiologic roles and applications in cancer. Mol Cancer Res 2: 257-280.
    • (2004) Mol Cancer Res , vol.2 , pp. 257-280
    • Borgono, C.A.1    Miacovos, M.P.2    Diamandis, E.P.3
  • 31
    • 70549107710 scopus 로고    scopus 로고
    • Mitochondrial cell death effectors
    • Brenner D, Mak TW, (2009) Mitochondrial cell death effectors. Curr Opin Cell Biol 21: 871-877.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 871-877
    • Brenner, D.1    Mak, T.W.2
  • 32
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: the executioners of apoptosis
    • Cohen GM, (1997) Caspases: the executioners of apoptosis. Biochem J 326 (Pt 1): 1-16.
    • (1997) Biochem J , vol.326 , Issue.Pt 1 , pp. 1-16
    • Cohen, G.M.1
  • 33
    • 0036069819 scopus 로고    scopus 로고
    • Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim
    • Hildeman DA, Zhu Y, Mitchell TC, Bouillet P, Strasser A, et al. (2002) Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity 16: 759-767.
    • (2002) Immunity , vol.16 , pp. 759-767
    • Hildeman, D.A.1    Zhu, Y.2    Mitchell, T.C.3    Bouillet, P.4    Strasser, A.5
  • 34
    • 0033800844 scopus 로고    scopus 로고
    • Molecular mechanism of staurosporine-induced apoptosis in osteoblasts
    • Chae HJ, Kang JS, Byun JO, Han KS, Kim DU, et al. (2000) Molecular mechanism of staurosporine-induced apoptosis in osteoblasts. Pharmacol Res 42: 373-381.
    • (2000) Pharmacol Res , vol.42 , pp. 373-381
    • Chae, H.J.1    Kang, J.S.2    Byun, J.O.3    Han, K.S.4    Kim, D.U.5
  • 35
    • 4444372444 scopus 로고    scopus 로고
    • Staurosporine induces apoptosis of melanoma by both caspase-dependent and -independent apoptotic pathways
    • Zhang XD, Gillespie SK, Hersey P, (2004) Staurosporine induces apoptosis of melanoma by both caspase-dependent and-independent apoptotic pathways. Mol Cancer Ther 3: 187-197.
    • (2004) Mol Cancer Ther , vol.3 , pp. 187-197
    • Zhang, X.D.1    Gillespie, S.K.2    Hersey, P.3
  • 36
    • 0027479655 scopus 로고
    • Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation
    • Brown DG, Sun XM, Cohen GM, (1993) Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J Biol Chem 268: 3037-3039.
    • (1993) J Biol Chem , vol.268 , pp. 3037-3039
    • Brown, D.G.1    Sun, X.M.2    Cohen, G.M.3
  • 37
    • 0025613973 scopus 로고
    • Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonistic
    • Zacharchuk CM, Mercep M, Chakraborti PK, Simons SS Jr, Ashwell JD, (1990) Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonistic. J Immunol 145: 4037-4045.
    • (1990) J Immunol , vol.145 , pp. 4037-4045
    • Zacharchuk, C.M.1    Mercep, M.2    Chakraborti, P.K.3    Simons Jr., S.S.4    Ashwell, J.D.5
  • 38
    • 0023120729 scopus 로고
    • Cell growth cycle block of T cell hybridomas upon activation with antigen
    • Ashwell JD, Cunningham RE, Noguchi PD, Hernandez D, (1987) Cell growth cycle block of T cell hybridomas upon activation with antigen. J Exp Med 165: 173-194.
    • (1987) J Exp Med , vol.165 , pp. 173-194
    • Ashwell, J.D.1    Cunningham, R.E.2    Noguchi, P.D.3    Hernandez, D.4
  • 39
    • 0034096723 scopus 로고    scopus 로고
    • The topoisomerase inhibitors camptothecin and etoposide induce a CD95-independent apoptosis of activated peripheral lymphocytes
    • Ferraro C, Quemeneur L, Fournel S, Prigent AF, Revillard JP, et al. (2000) The topoisomerase inhibitors camptothecin and etoposide induce a CD95-independent apoptosis of activated peripheral lymphocytes. Cell Death Differ 7: 197-206.
    • (2000) Cell Death Differ , vol.7 , pp. 197-206
    • Ferraro, C.1    Quemeneur, L.2    Fournel, S.3    Prigent, A.F.4    Revillard, J.P.5
  • 40
    • 0028262128 scopus 로고
    • Determination of lymphocyte division by flow cytometry
    • Lyons AB, Parish CR, (1994) Determination of lymphocyte division by flow cytometry. J Immunol Methods 171: 131-137.
    • (1994) J Immunol Methods , vol.171 , pp. 131-137
    • Lyons, A.B.1    Parish, C.R.2
  • 41
    • 77958586103 scopus 로고    scopus 로고
    • Stochastic models of lymphocyte proliferation and death
    • Zilman A, Ganusov VV, Perelson AS, (2010) Stochastic models of lymphocyte proliferation and death. PLoS One 5.
    • (2010) PLoS One , vol.5
    • Zilman, A.1    Ganusov, V.V.2    Perelson, A.S.3
  • 42
    • 0030806351 scopus 로고    scopus 로고
    • Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions
    • Eischen CM, Kottke TJ, Martins LM, Basi GS, Tung JS, et al. (1997) Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions. Blood 90: 935-943.
    • (1997) Blood , vol.90 , pp. 935-943
    • Eischen, C.M.1    Kottke, T.J.2    Martins, L.M.3    Basi, G.S.4    Tung, J.S.5
  • 43
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis
    • Kaufmann S, Desnoyers S, Ottaviano Y, Davidson N, Poirier G, (1993) Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res 53: 3976-3985.
    • (1993) Cancer Res , vol.53 , pp. 3976-3985
    • Kaufmann, S.1    Desnoyers, S.2    Ottaviano, Y.3    Davidson, N.4    Poirier, G.5
  • 44
    • 0037418238 scopus 로고    scopus 로고
    • JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
    • Lei K, Davis RJ, (2003) JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci U S A 100: 2432-2437.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2432-2437
    • Lei, K.1    Davis, R.J.2
  • 45
    • 0842342610 scopus 로고    scopus 로고
    • Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling
    • Chen D, Zhou Q, (2004) Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling. Proc Natl Acad Sci U S A 101: 1235-1240.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 1235-1240
    • Chen, D.1    Zhou, Q.2
  • 47
    • 0037253347 scopus 로고    scopus 로고
    • PARticipation in inflammation
    • Coughlin SR, Camerer E, (2003) PARticipation in inflammation. J Clin Invest 111: 25-27.
    • (2003) J Clin Invest , vol.111 , pp. 25-27
    • Coughlin, S.R.1    Camerer, E.2
  • 48
    • 13444249470 scopus 로고    scopus 로고
    • Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response
    • Steinhoff M, Buddenkotte J, Shpacovitch V, Rattenholl A, Moormann C, et al. (2005) Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response. Endocr Rev 26: 1-43.
    • (2005) Endocr Rev , vol.26 , pp. 1-43
    • Steinhoff, M.1    Buddenkotte, J.2    Shpacovitch, V.3    Rattenholl, A.4    Moormann, C.5
  • 49
    • 27144507922 scopus 로고    scopus 로고
    • PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism
    • Tantivejkul K, Loberg RD, Mawocha SC, Day LL, John LS, et al. (2005) PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism. J Cell Biochem 96: 641-652.
    • (2005) J Cell Biochem , vol.96 , pp. 641-652
    • Tantivejkul, K.1    Loberg, R.D.2    Mawocha, S.C.3    Day, L.L.4    John, L.S.5
  • 50
    • 68049143326 scopus 로고    scopus 로고
    • Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis
    • Yang E, Boire A, Agarwal A, Nguyen N, O'Callaghan K, et al. (2009) Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis. Cancer Res 69: 6223-6231.
    • (2009) Cancer Res , vol.69 , pp. 6223-6231
    • Yang, E.1    Boire, A.2    Agarwal, A.3    Nguyen, N.4    O'Callaghan, K.5
  • 51
    • 0141905920 scopus 로고    scopus 로고
    • Thrombin inhibits Bim (Bcl-2-interacting mediator of cell death) expression and prevents serum-withdrawal-induced apoptosis via protease-activated receptor 1
    • Chalmers CJ, Balmanno K, Hadfield K, Ley R, Cook SJ, (2003) Thrombin inhibits Bim (Bcl-2-interacting mediator of cell death) expression and prevents serum-withdrawal-induced apoptosis via protease-activated receptor 1. Biochem J 375: 99-109.
    • (2003) Biochem J , vol.375 , pp. 99-109
    • Chalmers, C.J.1    Balmanno, K.2    Hadfield, K.3    Ley, R.4    Cook, S.J.5
  • 52
    • 33746464526 scopus 로고    scopus 로고
    • Protease-activated receptor-1 protects rat astrocytes from apoptotic cell death via JNK-mediated release of the chemokine GRO/CINC-1
    • Wang Y, Luo W, Stricker R, Reiser G, (2006) Protease-activated receptor-1 protects rat astrocytes from apoptotic cell death via JNK-mediated release of the chemokine GRO/CINC-1. J Neurochem 98: 1046-1060.
    • (2006) J Neurochem , vol.98 , pp. 1046-1060
    • Wang, Y.1    Luo, W.2    Stricker, R.3    Reiser, G.4
  • 53
    • 39849101009 scopus 로고    scopus 로고
    • Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets
    • Han MH, Hwang SI, Roy DB, Lundgren DH, Price JV, et al. (2008) Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature 451: 1076-1081.
    • (2008) Nature , vol.451 , pp. 1076-1081
    • Han, M.H.1    Hwang, S.I.2    Roy, D.B.3    Lundgren, D.H.4    Price, J.V.5
  • 54
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, et al. (1999) Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 286: 1735-1738.
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.3    Tarlinton, D.M.4    Kay, T.W.5
  • 55
    • 0037148840 scopus 로고    scopus 로고
    • BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
    • Bouillet P, Purton JF, Godfrey DI, Zhang LC, Coultas L, et al. (2002) BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 415: 922-926.
    • (2002) Nature , vol.415 , pp. 922-926
    • Bouillet, P.1    Purton, J.F.2    Godfrey, D.I.3    Zhang, L.C.4    Coultas, L.5
  • 56
    • 0141959215 scopus 로고    scopus 로고
    • Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells
    • Enders A, Bouillet P, Puthalakath H, Xu Y, Tarlinton DM, et al. (2003) Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells. J Exp Med 198: 1119-1126.
    • (2003) J Exp Med , vol.198 , pp. 1119-1126
    • Enders, A.1    Bouillet, P.2    Puthalakath, H.3    Xu, Y.4    Tarlinton, D.M.5
  • 57
    • 0344198588 scopus 로고    scopus 로고
    • Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim
    • Pellegrini M, Belz G, Bouillet P, Strasser A, (2003) Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim. Proc Natl Acad Sci U S A 100: 14175-14180.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 14175-14180
    • Pellegrini, M.1    Belz, G.2    Bouillet, P.3    Strasser, A.4
  • 58
    • 0030730261 scopus 로고    scopus 로고
    • Nervous system specific expression of a novel serine protease: regulation in the adult rat spinal cord by excitotoxic injury
    • Scarisbrick IA, Towner MD, Isackson PJ, (1997) Nervous system specific expression of a novel serine protease: regulation in the adult rat spinal cord by excitotoxic injury. J Neurosci 17: 8156-8168.
    • (1997) J Neurosci , vol.17 , pp. 8156-8168
    • Scarisbrick, I.A.1    Towner, M.D.2    Isackson, P.J.3
  • 59
    • 0035115850 scopus 로고    scopus 로고
    • The expanded human kallikrein (KLK) gene family: genomic organization, tissue-specific expression and potential functions
    • Clements J, Hooper J, Dong Y, Harvey T, (2001) The expanded human kallikrein (KLK) gene family: genomic organization, tissue-specific expression and potential functions. Biol Chem 382: 5-14.
    • (2001) Biol Chem , vol.382 , pp. 5-14
    • Clements, J.1    Hooper, J.2    Dong, Y.3    Harvey, T.4
  • 60
    • 0029844185 scopus 로고    scopus 로고
    • A novel protease homolog differentially expressed in breast and ovarian cancer
    • Anisowicz A, Sotiropoulou G, Stenman G, Mok SC, Sager R, (1996) A novel protease homolog differentially expressed in breast and ovarian cancer. Mol Med 2: 624-636.
    • (1996) Mol Med , vol.2 , pp. 624-636
    • Anisowicz, A.1    Sotiropoulou, G.2    Stenman, G.3    Mok, S.C.4    Sager, R.5
  • 61
    • 18744363878 scopus 로고    scopus 로고
    • Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease
    • Mitsui S, Okui A, Uemura H, Mizuno T, Yamada T, et al. (2002) Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease. Ann N Y Acad Sci 977: 216-223.
    • (2002) Ann N Y Acad Sci , vol.977 , pp. 216-223
    • Mitsui, S.1    Okui, A.2    Uemura, H.3    Mizuno, T.4    Yamada, T.5
  • 62
    • 55249103819 scopus 로고    scopus 로고
    • Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma
    • Ruckert F, Hennig M, Petraki CD, Wehrum D, Distler M, et al. (2008) Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma. Br J Cancer 99: 1484-1492.
    • (2008) Br J Cancer , vol.99 , pp. 1484-1492
    • Ruckert, F.1    Hennig, M.2    Petraki, C.D.3    Wehrum, D.4    Distler, M.5
  • 63
    • 70349663978 scopus 로고    scopus 로고
    • KLK6 and KLK13 predict tumor recurrence in epithelial ovarian carcinoma
    • White NM, Mathews M, Yousef GM, Prizada A, Popadiuk C, et al. (2009) KLK6 and KLK13 predict tumor recurrence in epithelial ovarian carcinoma. Br J Cancer 101: 1107-1113.
    • (2009) Br J Cancer , vol.101 , pp. 1107-1113
    • White, N.M.1    Mathews, M.2    Yousef, G.M.3    Prizada, A.4    Popadiuk, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.