-
1
-
-
0036266204
-
Activity of a newly identified serine protease in CNS demyelination
-
Scarisbrick IA, Blaber SI, Lucchinetti CF, Genain CP, Blaber M, et al. (2002) Activity of a newly identified serine protease in CNS demyelination. Brain 125: 1283-1296.
-
(2002)
Brain
, vol.125
, pp. 1283-1296
-
-
Scarisbrick, I.A.1
Blaber, S.I.2
Lucchinetti, C.F.3
Genain, C.P.4
Blaber, M.5
-
2
-
-
10644260335
-
Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease
-
Christophi GP, Isackson PJ, Blaber SI, Blaber M, Rodriguez M, et al. (2004) Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease. J Neurochem 91: 1439-1449.
-
(2004)
J Neurochem
, vol.91
, pp. 1439-1449
-
-
Christophi, G.P.1
Isackson, P.J.2
Blaber, S.I.3
Blaber, M.4
Rodriguez, M.5
-
3
-
-
33748093565
-
Potential scope of action of tissue kallikreins in CNS immune-mediated disease
-
Scarisbrick IA, Blaber SI, Tingling JT, Rodriguez M, Blaber M, et al. (2006) Potential scope of action of tissue kallikreins in CNS immune-mediated disease. J Neuroimmunology 178: 167-176.
-
(2006)
J Neuroimmunology
, vol.178
, pp. 167-176
-
-
Scarisbrick, I.A.1
Blaber, S.I.2
Tingling, J.T.3
Rodriguez, M.4
Blaber, M.5
-
4
-
-
47549115421
-
Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration
-
Scarisbrick IA, Linbo R, Vandell AG, Keegan M, Blaber SI, et al. (2008) Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration. Biol Chem 389: 739-745.
-
(2008)
Biol Chem
, vol.389
, pp. 739-745
-
-
Scarisbrick, I.A.1
Linbo, R.2
Vandell, A.G.3
Keegan, M.4
Blaber, S.I.5
-
5
-
-
4644286907
-
Targeting kallikrein 6-proteolysis attenuates CNS inflammatory disease
-
Blaber SI, Ciric B, Christophi GP, Bernett MJ, Blaber M, et al. (2004) Targeting kallikrein 6-proteolysis attenuates CNS inflammatory disease. FASEB J 19: 920-922.
-
(2004)
FASEB J
, vol.19
, pp. 920-922
-
-
Blaber, S.I.1
Ciric, B.2
Christophi, G.P.3
Bernett, M.J.4
Blaber, M.5
-
6
-
-
0037025309
-
Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system
-
Bernett MJ, Blaber SI, Scarisbrick IA, Dhanarajan P, Thompson SM, et al. (2002) Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system. J Biol Chem 277: 24562-24570.
-
(2002)
J Biol Chem
, vol.277
, pp. 24562-24570
-
-
Bernett, M.J.1
Blaber, S.I.2
Scarisbrick, I.A.3
Dhanarajan, P.4
Thompson, S.M.5
-
7
-
-
0037192167
-
Enzymatic properties of rat myelencephalon-specific protease
-
Blaber SI, Scarisbrick IA, Bernett MJ, Dhanarajan P, Seavy MA, et al. (2002) Enzymatic properties of rat myelencephalon-specific protease. Biochemistry 41: 1165-1173.
-
(2002)
Biochemistry
, vol.41
, pp. 1165-1173
-
-
Blaber, S.I.1
Scarisbrick, I.A.2
Bernett, M.J.3
Dhanarajan, P.4
Seavy, M.A.5
-
8
-
-
33645634897
-
Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects
-
Angelo PF, Lima AR, Alves FM, Blaber SI, Scarisbrick IA, et al. (2006) Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects. J Biol Chem 281: 3116-3126.
-
(2006)
J Biol Chem
, vol.281
, pp. 3116-3126
-
-
Angelo, P.F.1
Lima, A.R.2
Alves, F.M.3
Blaber, S.I.4
Scarisbrick, I.A.5
-
9
-
-
33845955449
-
Proteinase-activated receptors, targets for kallikrein signaling
-
Oikonomopoulou K, Hansen KK, Saifeddine M, Tea I, Blaber M, et al. (2006) Proteinase-activated receptors, targets for kallikrein signaling. J Biol Chem 281: 32095-32112.
-
(2006)
J Biol Chem
, vol.281
, pp. 32095-32112
-
-
Oikonomopoulou, K.1
Hansen, K.K.2
Saifeddine, M.3
Tea, I.4
Blaber, M.5
-
10
-
-
33745664539
-
Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs)
-
Oikonomopoulou K, Hansen KK, Saifeddine M, Vergnolle N, Tea I, et al. (2006) Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs). Biol Chem 387: 817-824.
-
(2006)
Biol Chem
, vol.387
, pp. 817-824
-
-
Oikonomopoulou, K.1
Hansen, K.K.2
Saifeddine, M.3
Vergnolle, N.4
Tea, I.5
-
11
-
-
53749092612
-
Protease Activated Receptor Dependent and Independent Signaling by Kallikreins 1 and 6 in CNS Neuron and Astroglial Cell Lines
-
Vandell AG, Larson N, Laxmikanthan G, Panos M, Blaber SI, et al. (2008) Protease Activated Receptor Dependent and Independent Signaling by Kallikreins 1 and 6 in CNS Neuron and Astroglial Cell Lines. J Neurochem 107: 855-870.
-
(2008)
J Neurochem
, vol.107
, pp. 855-870
-
-
Vandell, A.G.1
Larson, N.2
Laxmikanthan, G.3
Panos, M.4
Blaber, S.I.5
-
12
-
-
45949100430
-
Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity
-
Shpacovitch V, Feld M, Hollenberg MD, Luger TA, Steinhoff M, (2008) Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity. J Leukoc Biol 83: 1309-1322.
-
(2008)
J Leukoc Biol
, vol.83
, pp. 1309-1322
-
-
Shpacovitch, V.1
Feld, M.2
Hollenberg, M.D.3
Luger, T.A.4
Steinhoff, M.5
-
13
-
-
0037960323
-
Tryptase activates peripheral blood mononuclear cells causing synthesis and release of TNF-a, IL-6 and IL-1B: possible relevance to multiple sclerosis
-
Malamud V, Vaaknin A, Abramsky O, Mor M, Burgess LE, et al. (2003) Tryptase activates peripheral blood mononuclear cells causing synthesis and release of TNF-a, IL-6 and IL-1B: possible relevance to multiple sclerosis. J Neuroimmunology 138: 115-122.
-
(2003)
J Neuroimmunology
, vol.138
, pp. 115-122
-
-
Malamud, V.1
Vaaknin, A.2
Abramsky, O.3
Mor, M.4
Burgess, L.E.5
-
14
-
-
0141816690
-
Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells
-
Colongnato R, Slupsky JR, Jendrach M, Burysek L, Syrovets T, et al. (2003) Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells. Blood 102: 2645-2652.
-
(2003)
Blood
, vol.102
, pp. 2645-2652
-
-
Colongnato, R.1
Slupsky, J.R.2
Jendrach, M.3
Burysek, L.4
Syrovets, T.5
-
15
-
-
0038582714
-
Protease-activated receptor-2 signaling triggers dendritic cell development
-
Fields RC, Schoenecker JG, Hart JP, Hoffman MR, Pizzo SV, et al. (2003) Protease-activated receptor-2 signaling triggers dendritic cell development. Am J Path 162: 1817-1822.
-
(2003)
Am J Path
, vol.162
, pp. 1817-1822
-
-
Fields, R.C.1
Schoenecker, J.G.2
Hart, J.P.3
Hoffman, M.R.4
Pizzo, S.V.5
-
16
-
-
33746449323
-
Induction of IL-6 release from monocytes by serine proteinases and its potential mechanisms
-
Li T, Want H, He S, (2006) Induction of IL-6 release from monocytes by serine proteinases and its potential mechanisms. Scand J Immunol 64: 10-16.
-
(2006)
Scand J Immunol
, vol.64
, pp. 10-16
-
-
Li, T.1
Want, H.2
He, S.3
-
17
-
-
0028244420
-
Protease-dependent T cell activation: ligation of effector cell protease receptor-1 (EPR-1) stimulates lymphocyte proliferation
-
Altieri DC, Stamnes SJ, (1994) Protease-dependent T cell activation: ligation of effector cell protease receptor-1 (EPR-1) stimulates lymphocyte proliferation. Cell Immunol 155: 371-383.
-
(1994)
Cell Immunol
, vol.155
, pp. 371-383
-
-
Altieri, D.C.1
Stamnes, S.J.2
-
18
-
-
79953130546
-
Protease Activated Receptor-1 down-regulates the murine inflammatory and humoral response to Helicobacter pylori
-
Wee JL, Chionh YT, Ng GZ, Harbour SN, Allison C, et al. (2009) Protease Activated Receptor-1 down-regulates the murine inflammatory and humoral response to Helicobacter pylori. Gastroenterology.
-
(2009)
Gastroenterology
-
-
Wee, J.L.1
Chionh, Y.T.2
Ng, G.Z.3
Harbour, S.N.4
Allison, C.5
-
19
-
-
85047689926
-
A role for proteinase-activated receptor-1 in inflammatory bowel diseases
-
Vergnolle N, Cellars L, Mencarelli A, Rizzo G, Swaminathan S, et al. (2004) A role for proteinase-activated receptor-1 in inflammatory bowel diseases. J Clin Invest 114: 1444-1456.
-
(2004)
J Clin Invest
, vol.114
, pp. 1444-1456
-
-
Vergnolle, N.1
Cellars, L.2
Mencarelli, A.3
Rizzo, G.4
Swaminathan, S.5
-
20
-
-
0034614895
-
Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis
-
Cunningham MA, Rondeau E, Chen X, Coughlin SR, Holdsworth SR, et al. (2000) Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis. J Exp Med 191: 455-462.
-
(2000)
J Exp Med
, vol.191
, pp. 455-462
-
-
Cunningham, M.A.1
Rondeau, E.2
Chen, X.3
Coughlin, S.R.4
Holdsworth, S.R.5
-
21
-
-
17244377342
-
Reduction of arthritis severity in protease-activated receptor-deficient mice
-
Yang YH, Hall P, Little CB, Fosang AJ, Milenkovski G, et al. (2005) Reduction of arthritis severity in protease-activated receptor-deficient mice. Arthritis Rheum 52: 1325-1332.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1325-1332
-
-
Yang, Y.H.1
Hall, P.2
Little, C.B.3
Fosang, A.J.4
Milenkovski, G.5
-
22
-
-
70249093313
-
Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2
-
Kouzaki H, O'Grady SM, Lawrence CB, Kita H, (2009) Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2. J Immunol 183: 1427-1434.
-
(2009)
J Immunol
, vol.183
, pp. 1427-1434
-
-
Kouzaki, H.1
O'Grady, S.M.2
Lawrence, C.B.3
Kita, H.4
-
23
-
-
0037247658
-
Essential role for proteinase-activated receptor-2 in arthritis
-
Ferrell WR, Lockhart JC, Kelso EB, Dunning L, Plevin R, et al. (2003) Essential role for proteinase-activated receptor-2 in arthritis. J Clin Invest 111: 35-41.
-
(2003)
J Clin Invest
, vol.111
, pp. 35-41
-
-
Ferrell, W.R.1
Lockhart, J.C.2
Kelso, E.B.3
Dunning, L.4
Plevin, R.5
-
24
-
-
0036166557
-
Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear
-
Kawagoe J, Takizawa T, Matsumoto J, Tamiya M, Meek SE, et al. (2002) Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear. Jpn J Pharmacol 88: 77-84.
-
(2002)
Jpn J Pharmacol
, vol.88
, pp. 77-84
-
-
Kawagoe, J.1
Takizawa, T.2
Matsumoto, J.3
Tamiya, M.4
Meek, S.E.5
-
25
-
-
33344473933
-
Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis
-
Noorbakhsh F, Tsutsui S, Vergnolle N, Boven LA, Shariat N, et al. (2006) Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis. J Exp Med 203: 425-435.
-
(2006)
J Exp Med
, vol.203
, pp. 425-435
-
-
Noorbakhsh, F.1
Tsutsui, S.2
Vergnolle, N.3
Boven, L.A.4
Shariat, N.5
-
26
-
-
13944276781
-
1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding
-
Laxmikanthan G, Blaber SI, Bernett MJ, Scarisbrick IA, Juliano MA, et al. (2005) 1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding. Proteins 58: 802-814.
-
(2005)
Proteins
, vol.58
, pp. 802-814
-
-
Laxmikanthan, G.1
Blaber, S.I.2
Bernett, M.J.3
Scarisbrick, I.A.4
Juliano, M.A.5
-
27
-
-
0029838236
-
High level of circulating human tissue kallikrein induces hypotension in a transgenic mouse model
-
Song Q, Chao J, Chao L, (1996) High level of circulating human tissue kallikrein induces hypotension in a transgenic mouse model. Clin Exp Hypertens 18: 975-993.
-
(1996)
Clin Exp Hypertens
, vol.18
, pp. 975-993
-
-
Song, Q.1
Chao, J.2
Chao, L.3
-
28
-
-
0034543474
-
Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma
-
Diamandis EP, Yousef GM, Soosaipillai AR, Bunting P, (2000) Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma. Clin Biochem 33: 579-583.
-
(2000)
Clin Biochem
, vol.33
, pp. 579-583
-
-
Diamandis, E.P.1
Yousef, G.M.2
Soosaipillai, A.R.3
Bunting, P.4
-
29
-
-
0036017352
-
Decreased concentration of human kallikrein 6 in brain extracts of Alzheimer's disease patients
-
Zarghooni M, Soosaipillai A, Grass L, Scorilas A, Mirazimi N, et al. (2002) Decreased concentration of human kallikrein 6 in brain extracts of Alzheimer's disease patients. Clinical Biochemistry 35: 225-231.
-
(2002)
Clinical Biochemistry
, vol.35
, pp. 225-231
-
-
Zarghooni, M.1
Soosaipillai, A.2
Grass, L.3
Scorilas, A.4
Mirazimi, N.5
-
30
-
-
3543150203
-
Human tissue kallikreins: physiologic roles and applications in cancer
-
Borgono CA, Miacovos MP, Diamandis EP, (2004) Human tissue kallikreins: physiologic roles and applications in cancer. Mol Cancer Res 2: 257-280.
-
(2004)
Mol Cancer Res
, vol.2
, pp. 257-280
-
-
Borgono, C.A.1
Miacovos, M.P.2
Diamandis, E.P.3
-
31
-
-
70549107710
-
Mitochondrial cell death effectors
-
Brenner D, Mak TW, (2009) Mitochondrial cell death effectors. Curr Opin Cell Biol 21: 871-877.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 871-877
-
-
Brenner, D.1
Mak, T.W.2
-
32
-
-
0030931876
-
Caspases: the executioners of apoptosis
-
Cohen GM, (1997) Caspases: the executioners of apoptosis. Biochem J 326 (Pt 1): 1-16.
-
(1997)
Biochem J
, vol.326
, Issue.Pt 1
, pp. 1-16
-
-
Cohen, G.M.1
-
33
-
-
0036069819
-
Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim
-
Hildeman DA, Zhu Y, Mitchell TC, Bouillet P, Strasser A, et al. (2002) Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity 16: 759-767.
-
(2002)
Immunity
, vol.16
, pp. 759-767
-
-
Hildeman, D.A.1
Zhu, Y.2
Mitchell, T.C.3
Bouillet, P.4
Strasser, A.5
-
34
-
-
0033800844
-
Molecular mechanism of staurosporine-induced apoptosis in osteoblasts
-
Chae HJ, Kang JS, Byun JO, Han KS, Kim DU, et al. (2000) Molecular mechanism of staurosporine-induced apoptosis in osteoblasts. Pharmacol Res 42: 373-381.
-
(2000)
Pharmacol Res
, vol.42
, pp. 373-381
-
-
Chae, H.J.1
Kang, J.S.2
Byun, J.O.3
Han, K.S.4
Kim, D.U.5
-
35
-
-
4444372444
-
Staurosporine induces apoptosis of melanoma by both caspase-dependent and -independent apoptotic pathways
-
Zhang XD, Gillespie SK, Hersey P, (2004) Staurosporine induces apoptosis of melanoma by both caspase-dependent and-independent apoptotic pathways. Mol Cancer Ther 3: 187-197.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 187-197
-
-
Zhang, X.D.1
Gillespie, S.K.2
Hersey, P.3
-
36
-
-
0027479655
-
Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation
-
Brown DG, Sun XM, Cohen GM, (1993) Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J Biol Chem 268: 3037-3039.
-
(1993)
J Biol Chem
, vol.268
, pp. 3037-3039
-
-
Brown, D.G.1
Sun, X.M.2
Cohen, G.M.3
-
37
-
-
0025613973
-
Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonistic
-
Zacharchuk CM, Mercep M, Chakraborti PK, Simons SS Jr, Ashwell JD, (1990) Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonistic. J Immunol 145: 4037-4045.
-
(1990)
J Immunol
, vol.145
, pp. 4037-4045
-
-
Zacharchuk, C.M.1
Mercep, M.2
Chakraborti, P.K.3
Simons Jr., S.S.4
Ashwell, J.D.5
-
38
-
-
0023120729
-
Cell growth cycle block of T cell hybridomas upon activation with antigen
-
Ashwell JD, Cunningham RE, Noguchi PD, Hernandez D, (1987) Cell growth cycle block of T cell hybridomas upon activation with antigen. J Exp Med 165: 173-194.
-
(1987)
J Exp Med
, vol.165
, pp. 173-194
-
-
Ashwell, J.D.1
Cunningham, R.E.2
Noguchi, P.D.3
Hernandez, D.4
-
39
-
-
0034096723
-
The topoisomerase inhibitors camptothecin and etoposide induce a CD95-independent apoptosis of activated peripheral lymphocytes
-
Ferraro C, Quemeneur L, Fournel S, Prigent AF, Revillard JP, et al. (2000) The topoisomerase inhibitors camptothecin and etoposide induce a CD95-independent apoptosis of activated peripheral lymphocytes. Cell Death Differ 7: 197-206.
-
(2000)
Cell Death Differ
, vol.7
, pp. 197-206
-
-
Ferraro, C.1
Quemeneur, L.2
Fournel, S.3
Prigent, A.F.4
Revillard, J.P.5
-
40
-
-
0028262128
-
Determination of lymphocyte division by flow cytometry
-
Lyons AB, Parish CR, (1994) Determination of lymphocyte division by flow cytometry. J Immunol Methods 171: 131-137.
-
(1994)
J Immunol Methods
, vol.171
, pp. 131-137
-
-
Lyons, A.B.1
Parish, C.R.2
-
41
-
-
77958586103
-
Stochastic models of lymphocyte proliferation and death
-
Zilman A, Ganusov VV, Perelson AS, (2010) Stochastic models of lymphocyte proliferation and death. PLoS One 5.
-
(2010)
PLoS One
, vol.5
-
-
Zilman, A.1
Ganusov, V.V.2
Perelson, A.S.3
-
42
-
-
0030806351
-
Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions
-
Eischen CM, Kottke TJ, Martins LM, Basi GS, Tung JS, et al. (1997) Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions. Blood 90: 935-943.
-
(1997)
Blood
, vol.90
, pp. 935-943
-
-
Eischen, C.M.1
Kottke, T.J.2
Martins, L.M.3
Basi, G.S.4
Tung, J.S.5
-
43
-
-
0027255417
-
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis
-
Kaufmann S, Desnoyers S, Ottaviano Y, Davidson N, Poirier G, (1993) Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res 53: 3976-3985.
-
(1993)
Cancer Res
, vol.53
, pp. 3976-3985
-
-
Kaufmann, S.1
Desnoyers, S.2
Ottaviano, Y.3
Davidson, N.4
Poirier, G.5
-
44
-
-
0037418238
-
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
-
Lei K, Davis RJ, (2003) JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci U S A 100: 2432-2437.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 2432-2437
-
-
Lei, K.1
Davis, R.J.2
-
45
-
-
0842342610
-
Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling
-
Chen D, Zhou Q, (2004) Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling. Proc Natl Acad Sci U S A 101: 1235-1240.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1235-1240
-
-
Chen, D.1
Zhou, Q.2
-
46
-
-
33748743265
-
Dynamic role of kallikrein 6 in traumatic spinal cord injury
-
Scarisbrick IA, Sabharwal P, Cruz H, Larsen N, Vandell A, et al. (2006) Dynamic role of kallikrein 6 in traumatic spinal cord injury. Eur J Neuroscience 24: 1457-1469.
-
(2006)
Eur J Neuroscience
, vol.24
, pp. 1457-1469
-
-
Scarisbrick, I.A.1
Sabharwal, P.2
Cruz, H.3
Larsen, N.4
Vandell, A.5
-
47
-
-
0037253347
-
PARticipation in inflammation
-
Coughlin SR, Camerer E, (2003) PARticipation in inflammation. J Clin Invest 111: 25-27.
-
(2003)
J Clin Invest
, vol.111
, pp. 25-27
-
-
Coughlin, S.R.1
Camerer, E.2
-
48
-
-
13444249470
-
Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response
-
Steinhoff M, Buddenkotte J, Shpacovitch V, Rattenholl A, Moormann C, et al. (2005) Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response. Endocr Rev 26: 1-43.
-
(2005)
Endocr Rev
, vol.26
, pp. 1-43
-
-
Steinhoff, M.1
Buddenkotte, J.2
Shpacovitch, V.3
Rattenholl, A.4
Moormann, C.5
-
49
-
-
27144507922
-
PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism
-
Tantivejkul K, Loberg RD, Mawocha SC, Day LL, John LS, et al. (2005) PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism. J Cell Biochem 96: 641-652.
-
(2005)
J Cell Biochem
, vol.96
, pp. 641-652
-
-
Tantivejkul, K.1
Loberg, R.D.2
Mawocha, S.C.3
Day, L.L.4
John, L.S.5
-
50
-
-
68049143326
-
Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis
-
Yang E, Boire A, Agarwal A, Nguyen N, O'Callaghan K, et al. (2009) Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis. Cancer Res 69: 6223-6231.
-
(2009)
Cancer Res
, vol.69
, pp. 6223-6231
-
-
Yang, E.1
Boire, A.2
Agarwal, A.3
Nguyen, N.4
O'Callaghan, K.5
-
51
-
-
0141905920
-
Thrombin inhibits Bim (Bcl-2-interacting mediator of cell death) expression and prevents serum-withdrawal-induced apoptosis via protease-activated receptor 1
-
Chalmers CJ, Balmanno K, Hadfield K, Ley R, Cook SJ, (2003) Thrombin inhibits Bim (Bcl-2-interacting mediator of cell death) expression and prevents serum-withdrawal-induced apoptosis via protease-activated receptor 1. Biochem J 375: 99-109.
-
(2003)
Biochem J
, vol.375
, pp. 99-109
-
-
Chalmers, C.J.1
Balmanno, K.2
Hadfield, K.3
Ley, R.4
Cook, S.J.5
-
52
-
-
33746464526
-
Protease-activated receptor-1 protects rat astrocytes from apoptotic cell death via JNK-mediated release of the chemokine GRO/CINC-1
-
Wang Y, Luo W, Stricker R, Reiser G, (2006) Protease-activated receptor-1 protects rat astrocytes from apoptotic cell death via JNK-mediated release of the chemokine GRO/CINC-1. J Neurochem 98: 1046-1060.
-
(2006)
J Neurochem
, vol.98
, pp. 1046-1060
-
-
Wang, Y.1
Luo, W.2
Stricker, R.3
Reiser, G.4
-
53
-
-
39849101009
-
Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets
-
Han MH, Hwang SI, Roy DB, Lundgren DH, Price JV, et al. (2008) Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature 451: 1076-1081.
-
(2008)
Nature
, vol.451
, pp. 1076-1081
-
-
Han, M.H.1
Hwang, S.I.2
Roy, D.B.3
Lundgren, D.H.4
Price, J.V.5
-
54
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, et al. (1999) Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 286: 1735-1738.
-
(1999)
Science
, vol.286
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.3
Tarlinton, D.M.4
Kay, T.W.5
-
55
-
-
0037148840
-
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
-
Bouillet P, Purton JF, Godfrey DI, Zhang LC, Coultas L, et al. (2002) BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 415: 922-926.
-
(2002)
Nature
, vol.415
, pp. 922-926
-
-
Bouillet, P.1
Purton, J.F.2
Godfrey, D.I.3
Zhang, L.C.4
Coultas, L.5
-
56
-
-
0141959215
-
Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells
-
Enders A, Bouillet P, Puthalakath H, Xu Y, Tarlinton DM, et al. (2003) Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells. J Exp Med 198: 1119-1126.
-
(2003)
J Exp Med
, vol.198
, pp. 1119-1126
-
-
Enders, A.1
Bouillet, P.2
Puthalakath, H.3
Xu, Y.4
Tarlinton, D.M.5
-
57
-
-
0344198588
-
Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim
-
Pellegrini M, Belz G, Bouillet P, Strasser A, (2003) Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim. Proc Natl Acad Sci U S A 100: 14175-14180.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 14175-14180
-
-
Pellegrini, M.1
Belz, G.2
Bouillet, P.3
Strasser, A.4
-
58
-
-
0030730261
-
Nervous system specific expression of a novel serine protease: regulation in the adult rat spinal cord by excitotoxic injury
-
Scarisbrick IA, Towner MD, Isackson PJ, (1997) Nervous system specific expression of a novel serine protease: regulation in the adult rat spinal cord by excitotoxic injury. J Neurosci 17: 8156-8168.
-
(1997)
J Neurosci
, vol.17
, pp. 8156-8168
-
-
Scarisbrick, I.A.1
Towner, M.D.2
Isackson, P.J.3
-
59
-
-
0035115850
-
The expanded human kallikrein (KLK) gene family: genomic organization, tissue-specific expression and potential functions
-
Clements J, Hooper J, Dong Y, Harvey T, (2001) The expanded human kallikrein (KLK) gene family: genomic organization, tissue-specific expression and potential functions. Biol Chem 382: 5-14.
-
(2001)
Biol Chem
, vol.382
, pp. 5-14
-
-
Clements, J.1
Hooper, J.2
Dong, Y.3
Harvey, T.4
-
60
-
-
0029844185
-
A novel protease homolog differentially expressed in breast and ovarian cancer
-
Anisowicz A, Sotiropoulou G, Stenman G, Mok SC, Sager R, (1996) A novel protease homolog differentially expressed in breast and ovarian cancer. Mol Med 2: 624-636.
-
(1996)
Mol Med
, vol.2
, pp. 624-636
-
-
Anisowicz, A.1
Sotiropoulou, G.2
Stenman, G.3
Mok, S.C.4
Sager, R.5
-
61
-
-
18744363878
-
Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease
-
Mitsui S, Okui A, Uemura H, Mizuno T, Yamada T, et al. (2002) Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease. Ann N Y Acad Sci 977: 216-223.
-
(2002)
Ann N Y Acad Sci
, vol.977
, pp. 216-223
-
-
Mitsui, S.1
Okui, A.2
Uemura, H.3
Mizuno, T.4
Yamada, T.5
-
62
-
-
55249103819
-
Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma
-
Ruckert F, Hennig M, Petraki CD, Wehrum D, Distler M, et al. (2008) Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma. Br J Cancer 99: 1484-1492.
-
(2008)
Br J Cancer
, vol.99
, pp. 1484-1492
-
-
Ruckert, F.1
Hennig, M.2
Petraki, C.D.3
Wehrum, D.4
Distler, M.5
-
63
-
-
70349663978
-
KLK6 and KLK13 predict tumor recurrence in epithelial ovarian carcinoma
-
White NM, Mathews M, Yousef GM, Prizada A, Popadiuk C, et al. (2009) KLK6 and KLK13 predict tumor recurrence in epithelial ovarian carcinoma. Br J Cancer 101: 1107-1113.
-
(2009)
Br J Cancer
, vol.101
, pp. 1107-1113
-
-
White, N.M.1
Mathews, M.2
Yousef, G.M.3
Prizada, A.4
Popadiuk, C.5
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