Protease-activated receptor-1 protects rat astrocytes from apoptotic cell death via JNK-mediated release of the chemokine GRO/CINC-1

Journal of Neurochemistry

Volumn 98, Issue 4, 2006, Pages 1046-1060

  Wang, Yingfei ^a   Luo, Weibo ^a   Stricker, Rolf ^a   Reiser, Georg ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Apoptosis; c Jun N terminal kinase; Chemokine receptor CXCR2; Mitogen activated protein kinase; Neuroprotection; Thrombin

Indexed keywords

CERAMIDE; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CXCR2; CYTOCHROME C; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEINASE ACTIVATED RECEPTOR 1; SB 332235; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; THROMBIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME RELEASE; MITOCHONDRION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; UPREGULATION;

ANIMALS; APOPTOSIS; ASTROCYTES; BLOTTING, WESTERN; CELLS, CULTURED; CERAMIDES; CHEMOKINES, CXC; CYTOCHROMES C; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; JNK MITOGEN-ACTIVATED PROTEIN KINASES; L-LACTATE DEHYDROGENASE; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROPROTECTIVE AGENTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RECEPTOR, PAR-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THROMBIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33746464526     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03950.x     Document Type: Article

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