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Volumn 107, Issue 3, 2008, Pages 855-870

Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines

Author keywords

Astrocyte; Bradykinin; Mitogen activated protein kinase; Neuron; Protease activated receptor; Protein kinase B

Indexed keywords

BRADYKININ B2 RECEPTOR; CALCIUM ION; KALLIKREIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; PROTEIN KLK1; PROTEINASE ACTIVATED RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 53749092612     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05658.x     Document Type: Article
Times cited : (63)

References (85)
  • 1
    • 38449113059 scopus 로고    scopus 로고
    • Proteinase-activated receptor-2 exerts protective and pathogenic cell type-specific effects in Alzheimer's disease
    • Afkhami-Goli A., Noorbakhsh F., Keller A. J. et al. (2007) Proteinase-activated receptor-2 exerts protective and pathogenic cell type-specific effects in Alzheimer's disease. J. Immunol. 179, 5493 5503.
    • (2007) J. Immunol. , vol.179 , pp. 5493-5503
    • Afkhami-Goli, A.1    Noorbakhsh, F.2    Keller, A.J.3
  • 2
    • 34548246560 scopus 로고    scopus 로고
    • Learning and memory deficits in mice lacking protease activated receptor-1
    • Almonte A. G., Hamill C. E., Chhatwal J. P. et al. (2007) Learning and memory deficits in mice lacking protease activated receptor-1. Neurobiol. Learn. Mem. 88, 295 304.
    • (2007) Neurobiol. Learn. Mem. , vol.88 , pp. 295-304
    • Almonte, A.G.1    Hamill, C.E.2    Chhatwal, J.P.3
  • 4
    • 34250159508 scopus 로고    scopus 로고
    • Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-Jun N-terminal kinase
    • Arthur P. G., Matich G. P., Pang W. W., Yu D. Y. Bogoyevitch M. A. (2007) Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-Jun N-terminal kinase. J. Neurochem. 102, 65 76.
    • (2007) J. Neurochem. , vol.102 , pp. 65-76
    • Arthur, P.G.1    Matich, G.P.2    Pang, W.W.3    Yu, D.Y.4    Bogoyevitch, M.A.5
  • 5
    • 0037025309 scopus 로고    scopus 로고
    • Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system
    • Bernett M. J., Blaber S. I., Scarisbrick I. A., Dhanarajan P., Thompson S. M. Blaber M. (2002) Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system. J. Biol. Chem. 277, 24562 24570.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24562-24570
    • Bernett, M.J.1    Blaber, S.I.2    Scarisbrick, I.A.3    Dhanarajan, P.4    Thompson, S.M.5    Blaber, M.6
  • 10
    • 8144222388 scopus 로고    scopus 로고
    • The emerging roles of human tissue kallikreins in cancer
    • Borgono C. A. Diamandis E. P. (2004) The emerging roles of human tissue kallikreins in cancer. Nat. Rev. Cancer 4, 876 890.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 876-890
    • Borgono, C.A.1    Diamandis, E.P.2
  • 13
    • 0035369623 scopus 로고    scopus 로고
    • Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway
    • Brunet A., Datta S. R. Greenberg M. E. (2001) Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr. Opin. Neurobiol. 11, 297 305.
    • (2001) Curr. Opin. Neurobiol. , vol.11 , pp. 297-305
    • Brunet, A.1    Datta, S.R.2    Greenberg, M.E.3
  • 14
    • 33646011568 scopus 로고    scopus 로고
    • Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes
    • Bushell T. J., Plevin R., Cobb S. Irving A. J. (2006) Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes. Neuropharmacology 50, 714 725.
    • (2006) Neuropharmacology , vol.50 , pp. 714-725
    • Bushell, T.J.1    Plevin, R.2    Cobb, S.3    Irving, A.J.4
  • 15
    • 0021255909 scopus 로고
    • Degradation of apolipoprotein B-100 of human plasma low density lipoproteins by tissue and plasma kallikreins
    • Cardin A. D., Witt K. R., Chao J., Margolius H. S., Donaldson V. H. Jackson R. L. (1984) Degradation of apolipoprotein B-100 of human plasma low density lipoproteins by tissue and plasma kallikreins. J. Biol. Chem. 259, 8522 8528.
    • (1984) J. Biol. Chem. , vol.259 , pp. 8522-8528
    • Cardin, A.D.1    Witt, K.R.2    Chao, J.3    Margolius, H.S.4    Donaldson, V.H.5    Jackson, R.L.6
  • 16
    • 32844461449 scopus 로고    scopus 로고
    • Experimental therapy with tissue kallikrein against cerebral ischemia
    • Chao J. Chao L. (2006) Experimental therapy with tissue kallikrein against cerebral ischemia. Front Biosci. 11, 1323 1327.
    • (2006) Front Biosci. , vol.11 , pp. 1323-1327
    • Chao, J.1    Chao, L.2
  • 18
    • 0038383698 scopus 로고    scopus 로고
    • Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo
    • Choi S. H., Joe E. H., Kim S. U. Jin B. K. (2003) Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo. J. Neurosci. 23, 5877 5886.
    • (2003) J. Neurosci. , vol.23 , pp. 5877-5886
    • Choi, S.H.1    Joe, E.H.2    Kim, S.U.3    Jin, B.K.4
  • 19
    • 15044339552 scopus 로고    scopus 로고
    • Phosphorylation of PTEN and Akt in astrocytes of the rat hippocampus following transient forebrain ischemia
    • Choi J. S., Park H. J., Kim H. Y., Kim S. Y., Lee J. E., Choi Y. S., Chun M. H., Chung J. W. Lee M. Y. (2005) Phosphorylation of PTEN and Akt in astrocytes of the rat hippocampus following transient forebrain ischemia. Cell Tissue Res. 319, 359 366.
    • (2005) Cell Tissue Res. , vol.319 , pp. 359-366
    • Choi, J.S.1    Park, H.J.2    Kim, H.Y.3    Kim, S.Y.4    Lee, J.E.5    Choi, Y.S.6    Chun, M.H.7    Chung, J.W.8    Lee, M.Y.9
  • 20
    • 10644260335 scopus 로고    scopus 로고
    • Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease
    • Christophi G. P., Isackson P. J., Blaber S. I., Blaber M., Rodriguez M. Scarisbrick I. A. (2004) Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease. J. Neurochem. 91, 1439 1449.
    • (2004) J. Neurochem. , vol.91 , pp. 1439-1449
    • Christophi, G.P.1    Isackson, P.J.2    Blaber, S.I.3    Blaber, M.4    Rodriguez, M.5    Scarisbrick, I.A.6
  • 21
    • 0033662889 scopus 로고    scopus 로고
    • Upregulation of neurotoxic serine proteases, prothrombin, and protease-activated receptor 1 early after spinal cord injury
    • Citron B. A., Smirnova I. V., Arnold P. M. Festoff B. W. (2000) Upregulation of neurotoxic serine proteases, prothrombin, and protease-activated receptor 1 early after spinal cord injury. J. Neurotrauma 17, 1191 1203.
    • (2000) J. Neurotrauma , vol.17 , pp. 1191-1203
    • Citron, B.A.1    Smirnova, I.V.2    Arnold, P.M.3    Festoff, B.W.4
  • 22
    • 0035115850 scopus 로고    scopus 로고
    • The expanded human kallikrein (KLK) gene family: Genomic organization, tissue-specific expression and potential functions
    • Clements J., Hooper J., Dong Y. Harvey T. (2001) The expanded human kallikrein (KLK) gene family: genomic organization, tissue-specific expression and potential functions. Biol. Chem. 382, 5 14.
    • (2001) Biol. Chem. , vol.382 , pp. 5-14
    • Clements, J.1    Hooper, J.2    Dong, Y.3    Harvey, T.4
  • 25
    • 0029130479 scopus 로고
    • An analysis of astrocytic cell lines with different abilities to promote axon growth
    • Fok-Seang J., Smith-Thomas L. C., Meiners S. et al. (1995) An analysis of astrocytic cell lines with different abilities to promote axon growth. Brain Res. 689, 207 223.
    • (1995) Brain Res. , vol.689 , pp. 207-223
    • Fok-Seang, J.1    Smith-Thomas, L.C.2    Meiners, S.3
  • 26
    • 0034660448 scopus 로고    scopus 로고
    • Potentiation of NMDA receptor function by the serine protease thrombin
    • Gingrich M. B., Junge C. E., Lyuboslavsky P. Traynelis S. F. (2000) Potentiation of NMDA receptor function by the serine protease thrombin. J. Neurosci. 20, 4582 4595.
    • (2000) J. Neurosci. , vol.20 , pp. 4582-4595
    • Gingrich, M.B.1    Junge, C.E.2    Lyuboslavsky, P.3    Traynelis, S.F.4
  • 27
    • 23044478435 scopus 로고    scopus 로고
    • Release of bradykinin and expression of kinin B2 receptors in the brain: Role for cell death and brain edema formation after focal cerebral ischemia in mice
    • Groger M., Lebesgue D., Pruneau D., Relton J., Kim S. W., Nussberger J. Plesnila N. (2005) Release of bradykinin and expression of kinin B2 receptors in the brain: role for cell death and brain edema formation after focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 25, 978 989.
    • (2005) J. Cereb. Blood Flow Metab. , vol.25 , pp. 978-989
    • Groger, M.1    Lebesgue, D.2    Pruneau, D.3    Relton, J.4    Kim, S.W.5    Nussberger, J.6    Plesnila, N.7
  • 28
    • 34548360527 scopus 로고    scopus 로고
    • Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1
    • Hamill C. E., Caudle W. M., Richardson J. R., Yuan H., Pennell K. D., Greene J. G., Miller G. W. Traynelis S. F. (2007) Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1. Mol. Pharmacol. 72, 653 664.
    • (2007) Mol. Pharmacol. , vol.72 , pp. 653-664
    • Hamill, C.E.1    Caudle, W.M.2    Richardson, J.R.3    Yuan, H.4    Pennell, K.D.5    Greene, J.G.6    Miller, G.W.7    Traynelis, S.F.8
  • 29
    • 33645744898 scopus 로고    scopus 로고
    • Positive cooperativity between the thrombin and bradykinin B2 receptors enhances arachidonic acid release
    • Hecquet C., Biyashev D., Tan F. Erdos E. G. (2006) Positive cooperativity between the thrombin and bradykinin B2 receptors enhances arachidonic acid release. Am. J. Physiol. Heart Circ. Physiol. 290, H948 H958.
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.290
    • Hecquet, C.1    Biyashev, D.2    Tan, F.3    Erdos, E.G.4
  • 31
    • 0037336835 scopus 로고    scopus 로고
    • Tissue kallikrein actions at the rabbit natural or recombinant kinin B2 receptors
    • Houle S., Molinaro G., Adam A. Marceau F. (2003) Tissue kallikrein actions at the rabbit natural or recombinant kinin B2 receptors. Hypertension 41, 611 617.
    • (2003) Hypertension , vol.41 , pp. 611-617
    • Houle, S.1    Molinaro, G.2    Adam, A.3    Marceau, F.4
  • 32
    • 0026748742 scopus 로고
    • Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers
    • Jalink K. Moolenaar W. H. (1992) Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers. J. Cell Biol. 118, 411 419.
    • (1992) J. Cell Biol. , vol.118 , pp. 411-419
    • Jalink, K.1    Moolenaar, W.H.2
  • 36
    • 0036905216 scopus 로고    scopus 로고
    • Delayed argatroban treatment reduces edema in a rat model of intracerebral hemorrhage
    • Kitaoka T., Hua Y., Xi G., Hoff J. T. Keep R. F. (2002) Delayed argatroban treatment reduces edema in a rat model of intracerebral hemorrhage. Stroke 33, 3012 3018.
    • (2002) Stroke , vol.33 , pp. 3012-3018
    • Kitaoka, T.1    Hua, Y.2    Xi, G.3    Hoff, J.T.4    Keep, R.F.5
  • 37
    • 13944276781 scopus 로고    scopus 로고
    • 1.70 a X-ray structure of human apo kallikrein 1: Structural changes upon peptide inhibitor/substrate binding
    • Laxmikanthan G., Blaber S. I., Bernett M. J., Scarisbrick I. A., Juliano M. A. Blaber M. (2005) 1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding. Proteins 58, 802 814.
    • (2005) Proteins , vol.58 , pp. 802-814
    • Laxmikanthan, G.1    Blaber, S.I.2    Bernett, M.J.3    Scarisbrick, I.A.4    Juliano, M.A.5    Blaber, M.6
  • 38
    • 0030975122 scopus 로고    scopus 로고
    • Seizures induced by intracerebral injection of thrombin: A model of intracerebral hemorrhage
    • Lee K. R., Drury I., Vitarbo E. Hoff J. T. (1997) Seizures induced by intracerebral injection of thrombin: a model of intracerebral hemorrhage. J. Neurosurg. 87, 73 78.
    • (1997) J. Neurosurg. , vol.87 , pp. 73-78
    • Lee, K.R.1    Drury, I.2    Vitarbo, E.3    Hoff, J.T.4
  • 39
    • 0037385753 scopus 로고    scopus 로고
    • Bradykinin antagonists reduce leukocyte-endothelium interactions after global cerebral ischemia
    • Lehmberg J., Beck J., Baethmann A. Uhl E. (2003) Bradykinin antagonists reduce leukocyte-endothelium interactions after global cerebral ischemia. J. Cereb. Blood Flow Metab. 23, 441 448.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 441-448
    • Lehmberg, J.1    Beck, J.2    Baethmann, A.3    Uhl, E.4
  • 40
    • 15444352446 scopus 로고    scopus 로고
    • Zyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brain
    • Little S. P., Dixon E. P., Norris F. et al. (1997) Zyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brain. J. Biol. Chem. 272, 25135 25142.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25135-25142
    • Little, S.P.1    Dixon, E.P.2    Norris, F.3
  • 41
    • 0027948168 scopus 로고
    • Proteolytic action of thrombin is required for electrical activity-dependent synapse reduction
    • Liu Y., Fields R. D., Festoff B. W. Nelson P. G. (1994) Proteolytic action of thrombin is required for electrical activity-dependent synapse reduction. Proc. Natl Acad. Sci. USA 91, 10300 10304.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 10300-10304
    • Liu, Y.1    Fields, R.D.2    Festoff, B.W.3    Nelson, P.G.4
  • 42
    • 0030601143 scopus 로고    scopus 로고
    • Effect of the bradykinin B2 receptor antagonist Hoe140 in experimental pneumococcal meningitis in the rat
    • Lorenzl S., Kodel U., Frei K. Pfister H. W. (1996) Effect of the bradykinin B2 receptor antagonist Hoe140 in experimental pneumococcal meningitis in the rat. Eur. J. Pharmacol. 308, 335 341.
    • (1996) Eur. J. Pharmacol. , vol.308 , pp. 335-341
    • Lorenzl, S.1    Kodel, U.2    Frei, K.3    Pfister, H.W.4
  • 43
    • 33646347134 scopus 로고    scopus 로고
    • Jab1, a novel protease-activated receptor-2 (PAR-2)-interacting protein, is involved in PAR-2-induced activation of activator protein-1
    • Luo W., Wang Y., Hanck T., Stricker R. Reiser G. (2006) Jab1, a novel protease-activated receptor-2 (PAR-2)-interacting protein, is involved in PAR-2-induced activation of activator protein-1. J. Biol. Chem. 281, 7927 7936.
    • (2006) J. Biol. Chem. , vol.281 , pp. 7927-7936
    • Luo, W.1    Wang, Y.2    Hanck, T.3    Stricker, R.4    Reiser, G.5
  • 45
    • 0023698784 scopus 로고
    • Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth
    • Monard D. (1988) Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth. Trends Neurosci. 11, 541 544.
    • (1988) Trends Neurosci. , vol.11 , pp. 541-544
    • Monard, D.1
  • 46
    • 17844388314 scopus 로고    scopus 로고
    • Traumatic injury activates protein kinase B/Akt in cultured astrocytes: Role of extracellular ATP and P2 purinergic receptors
    • Neary J. T., Kang Y., Tran M. Feld J. (2005) Traumatic injury activates protein kinase B/Akt in cultured astrocytes: role of extracellular ATP and P2 purinergic receptors. J. Neurotrauma 22, 491 500.
    • (2005) J. Neurotrauma , vol.22 , pp. 491-500
    • Neary, J.T.1    Kang, Y.2    Tran, M.3    Feld, J.4
  • 49
    • 33344473933 scopus 로고    scopus 로고
    • Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis
    • Noorbakhsh F., Tsutsui S., Vergnolle N. et al. (2006) Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis. J. Exp. Med. 203, 425 435.
    • (2006) J. Exp. Med. , vol.203 , pp. 425-435
    • Noorbakhsh, F.1    Tsutsui, S.2    Vergnolle, N.3
  • 50
    • 33745664539 scopus 로고    scopus 로고
    • Kallikrein-mediated cell signalling: Targeting proteinase-activated receptors (PARs)
    • Oikonomopoulou K., Hansen K. K., Saifeddine M. et al. (2006a) Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs). Biol. Chem. 387, 817 824.
    • (2006) Biol. Chem. , vol.387 , pp. 817-824
    • Oikonomopoulou, K.1    Hansen, K.K.2    Saifeddine, M.3
  • 51
    • 33845955449 scopus 로고    scopus 로고
    • Proteinase-activated receptors, targets for kallikrein signaling
    • Oikonomopoulou K., Hansen K. K., Saifeddine M. et al. (2006b) Proteinase-activated receptors, targets for kallikrein signaling. J. Biol. Chem. 281, 32095 32112.
    • (2006) J. Biol. Chem. , vol.281 , pp. 32095-32112
    • Oikonomopoulou, K.1    Hansen, K.K.2    Saifeddine, M.3
  • 52
    • 0018776031 scopus 로고
    • Identification of human glandular kallikrein in the beta cell of the pancreas
    • Ole-MoiYoi O. K., Pinkus G. S., Spragg J. Austen K. F. (1979) Identification of human glandular kallikrein in the beta cell of the pancreas. N. Engl. J. Med. 300, 1289 1294.
    • (1979) N. Engl. J. Med. , vol.300 , pp. 1289-1294
    • Ole-Moiyoi, O.K.1    Pinkus, G.S.2    Spragg, J.3    Austen, K.F.4
  • 53
    • 28944453944 scopus 로고    scopus 로고
    • Evidence that protease-activated receptor-2 mediates trypsin-induced reversal of stellation in cultured rat astrocytes
    • Park G. H., Ryu J. R., Shin C. Y., Choi M. S., Han B. H., Kim W. K., Kim H. C. Ko K. H. (2006) Evidence that protease-activated receptor-2 mediates trypsin-induced reversal of stellation in cultured rat astrocytes. Neurosci. Res. 54, 15 23.
    • (2006) Neurosci. Res. , vol.54 , pp. 15-23
    • Park, G.H.1    Ryu, J.R.2    Shin, C.Y.3    Choi, M.S.4    Han, B.H.5    Kim, W.K.6    Kim, H.C.7    Ko, K.H.8
  • 55
    • 0037199664 scopus 로고    scopus 로고
    • Increase of prothrombin-mRNA after global cerebral ischemia in rats, with constant expression of protease nexin-1 and protease-activated receptors
    • Riek-Burchardt M., Striggow F., Henrich-Noack P., Reiser G. Reymann K. G. (2002) Increase of prothrombin-mRNA after global cerebral ischemia in rats, with constant expression of protease nexin-1 and protease-activated receptors. Neurosci. Lett. 329, 181 184.
    • (2002) Neurosci. Lett. , vol.329 , pp. 181-184
    • Riek-Burchardt, M.1    Striggow, F.2    Henrich-Noack, P.3    Reiser, G.4    Reymann, K.G.5
  • 57
    • 0030730261 scopus 로고    scopus 로고
    • Nervous system specific expression of a novel serine protease: Regulation in the adult rat spinal cord by excitotoxic injury
    • Scarisbrick I. A., Towner M. D. Isackson P. J. (1997) Nervous system specific expression of a novel serine protease: regulation in the adult rat spinal cord by excitotoxic injury. J. Neurosci. 17, 8156 8168.
    • (1997) J. Neurosci. , vol.17 , pp. 8156-8168
    • Scarisbrick, I.A.1    Towner, M.D.2    Isackson, P.J.3
  • 58
    • 0034016029 scopus 로고    scopus 로고
    • Preferential expression of myelencephalon-specific protease by oligodendrocytes of the adult rat spinal cord white matter
    • Scarisbrick I. A., Asakura K., Blaber S., Blaber M., Isackson P. J., Bieto T., Rodriguez M. Windebank A. J. (2000) Preferential expression of myelencephalon-specific protease by oligodendrocytes of the adult rat spinal cord white matter. Glia 30, 219 230.
    • (2000) Glia , vol.30 , pp. 219-230
    • Scarisbrick, I.A.1    Asakura, K.2    Blaber, S.3    Blaber, M.4    Isackson, P.J.5    Bieto, T.6    Rodriguez, M.7    Windebank, A.J.8
  • 59
    • 0035848445 scopus 로고    scopus 로고
    • MSP, a trypsin-like serine protease, is abundantly expressed in the human nervous system
    • Scarisbrick I. A., Isackson P. J., Ciric B., Windebank A. J. Rodriguez M. (2001) MSP, a trypsin-like serine protease, is abundantly expressed in the human nervous system. J. Comp. Neurol. 431, 347 361.
    • (2001) J. Comp. Neurol. , vol.431 , pp. 347-361
    • Scarisbrick, I.A.1    Isackson, P.J.2    Ciric, B.3    Windebank, A.J.4    Rodriguez, M.5
  • 62
    • 33748743265 scopus 로고    scopus 로고
    • Dynamic role of kallikrein 6 in traumatic spinal cord injury
    • Scarisbrick I. A., Sabharwal P., Cruz H. et al. (2006b) Dynamic role of kallikrein 6 in traumatic spinal cord injury. Eur. J. Neurosci. 24, 1457 1469.
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 1457-1469
    • Scarisbrick, I.A.1    Sabharwal, P.2    Cruz, H.3
  • 63
    • 47549115421 scopus 로고    scopus 로고
    • Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration
    • Scarisbrick I. A., Linbo R. Vandell A., et al. (2008) Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration. Biol. Chem. 389, 739 745.
    • (2008) Biol. Chem. , vol.389 , pp. 739-745
    • Scarisbrick, I.A.1    Linbo, R.2    Vandell, A.3
  • 66
    • 0035876246 scopus 로고    scopus 로고
    • Induction of the plasminogen activator system accompanies peripheral nerve regeneration after sciatic nerve crush
    • Siconolfi L. B. Seeds N. W. (2001) Induction of the plasminogen activator system accompanies peripheral nerve regeneration after sciatic nerve crush. J. Neurosci. 21, 4336 4347.
    • (2001) J. Neurosci. , vol.21 , pp. 4336-4347
    • Siconolfi, L.B.1    Seeds, N.W.2
  • 67
    • 0034958701 scopus 로고    scopus 로고
    • Neuroprotective signal transduction in model motor neurons exposed to thrombin: G-protein modulation effects on neurite outgrowth, Ca(2+) mobilization, and apoptosis
    • Smirnova I. V., Citron B. A., Arnold P. M. Festoff B. W. (2001) Neuroprotective signal transduction in model motor neurons exposed to thrombin: G-protein modulation effects on neurite outgrowth, Ca(2+) mobilization, and apoptosis. J. Neurobiol. 48, 87 100.
    • (2001) J. Neurobiol. , vol.48 , pp. 87-100
    • Smirnova, I.V.1    Citron, B.A.2    Arnold, P.M.3    Festoff, B.W.4
  • 70
    • 0033971235 scopus 로고    scopus 로고
    • Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism
    • Steinhoff M., Vergnolle N., Young S. H. et al. (2000) Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. Nat. Med. 6, 151 158.
    • (2000) Nat. Med. , vol.6 , pp. 151-158
    • Steinhoff, M.1    Vergnolle, N.2    Young, S.H.3
  • 72
    • 0034053127 scopus 로고    scopus 로고
    • The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations
    • Striggow F., Riek M., Breder J., Henrich-Noack P., Reymann K. G. Reiser G. (2000) The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations. Proc. Natl Acad. Sci. USA 97, 2264 2269.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 2264-2269
    • Striggow, F.1    Riek, M.2    Breder, J.3    Henrich-Noack, P.4    Reymann, K.G.5    Reiser, G.6
  • 74
    • 9144223828 scopus 로고    scopus 로고
    • Differential expression of neuropsin and protease M/neurosin in oligodendrocytes after injury to the spinal cord
    • Terayama R., Bando Y., Takahashi T. Yoshida S. (2004) Differential expression of neuropsin and protease M/neurosin in oligodendrocytes after injury to the spinal cord. Glia 48, 91 101.
    • (2004) Glia , vol.48 , pp. 91-101
    • Terayama, R.1    Bando, Y.2    Takahashi, T.3    Yoshida, S.4
  • 75
    • 0031021357 scopus 로고    scopus 로고
    • An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus
    • Tsirka S. E., Rogove A. D., Bugge T. H., Degen J. L. Strickland S. (1997) An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus. J. Neurosci. 17, 543 552.
    • (1997) J. Neurosci. , vol.17 , pp. 543-552
    • Tsirka, S.E.1    Rogove, A.D.2    Bugge, T.H.3    Degen, J.L.4    Strickland, S.5
  • 76
    • 3042836519 scopus 로고    scopus 로고
    • Expression of myelencephalon-specific protease in transient middle cerebral artery occlusion model of rat brain
    • Uchida A., Oka Y., Aoyama M. et al. (2004) Expression of myelencephalon-specific protease in transient middle cerebral artery occlusion model of rat brain. Mol. Brain Res. 126, 129 136.
    • (2004) Mol. Brain Res. , vol.126 , pp. 129-136
    • Uchida, A.1    Oka, Y.2    Aoyama, M.3
  • 77
    • 0034927070 scopus 로고    scopus 로고
    • Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway
    • Vergnolle N., Bunnett N. W., Sharkey K. A. et al. (2001) Proteinase-activated receptor-2 and hyperalgesia: a novel pain pathway. Nat. Med. 7, 821 826.
    • (2001) Nat. Med. , vol.7 , pp. 821-826
    • Vergnolle, N.1    Bunnett, N.W.2    Sharkey, K.A.3
  • 78
    • 0036006726 scopus 로고    scopus 로고
    • Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling
    • Wang H., Ubl J. J. Reiser G. (2002a) Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling. Glia 37, 53 63.
    • (2002) Glia , vol.37 , pp. 53-63
    • Wang, H.1    Ubl, J.J.2    Reiser, G.3
  • 79
    • 0036838021 scopus 로고    scopus 로고
    • Thrombin (PAR-1)-induced proliferation in astrocytes via MAPK involves multiple signaling pathways
    • Wang H., Ubl J. J., Stricker R. Reiser G. (2002b) Thrombin (PAR-1)-induced proliferation in astrocytes via MAPK involves multiple signaling pathways. Am. J. Physiol. Cell Physiol. 283, C1351 C1364.
    • (2002) Am. J. Physiol. Cell Physiol. , vol.283
    • Wang, H.1    Ubl, J.J.2    Stricker, R.3    Reiser, G.4
  • 80
    • 33846316422 scopus 로고    scopus 로고
    • Proteinase-activated receptor-1 and -2 induce the release of chemokine GRO/CINC-1 from rat astrocytes via differential activation of JNK isoforms, evoking multiple protective pathways in brain
    • Wang Y., Luo W. Reiser G. (2007) Proteinase-activated receptor-1 and -2 induce the release of chemokine GRO/CINC-1 from rat astrocytes via differential activation of JNK isoforms, evoking multiple protective pathways in brain. Biochem. J. 401, 65 78.
    • (2007) Biochem. J. , vol.401 , pp. 65-78
    • Wang, Y.1    Luo, W.2    Reiser, G.3
  • 81
    • 0028914068 scopus 로고
    • Cellular localization of thrombin receptor mRNA in rat brain: Expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA
    • Weinstein J. R., Gold S. J., Cunningham D. D. Gall C. M. (1995) Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. J. Neurosci. 15, 2906 2919.
    • (1995) J. Neurosci. , vol.15 , pp. 2906-2919
    • Weinstein, J.R.1    Gold, S.J.2    Cunningham, D.D.3    Gall, C.M.4
  • 82
    • 0842332614 scopus 로고    scopus 로고
    • Kallikrein gene transfer protects against ischemic stroke by promoting glial cell migration and inhibiting apoptosis
    • Xia C. F., Yin H., Borlongan C. V., Chao L. Chao J. (2004) Kallikrein gene transfer protects against ischemic stroke by promoting glial cell migration and inhibiting apoptosis. Hypertension 43, 452 459.
    • (2004) Hypertension , vol.43 , pp. 452-459
    • Xia, C.F.1    Yin, H.2    Borlongan, C.V.3    Chao, L.4    Chao, J.5
  • 83
    • 0034827647 scopus 로고    scopus 로고
    • Acute tissue damage after injections of thrombin and plasmin into rat striatum
    • Xue M. Del Bigio M. R. (2001) Acute tissue damage after injections of thrombin and plasmin into rat striatum. Stroke 32, 2164 2169.
    • (2001) Stroke , vol.32 , pp. 2164-2169
    • Xue, M.1    Del Bigio, M.R.2


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