-
1
-
-
16844363097
-
A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
-
DOI 10.1038/ni1179
-
Fontenot JD, Rudensky AY. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat Immunol. 2005;6(4):331-337. (Pubitemid 41716769)
-
(2005)
Nature Immunology
, vol.6
, Issue.4
, pp. 331-337
-
-
Fontenot, J.D.1
Rudensky, A.Y.2
-
2
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou I, von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J Exp Med. 2004;199(10):1401-1408.
-
(2004)
J Exp Med
, vol.199
, Issue.10
, pp. 1401-1408
-
-
Apostolou, I.1
Von Boehmer, H.2
-
3
-
-
29244435493
-
Inducing and expanding regulatory T cell populations by foreign antigen
-
DOI 10.1038/ni1265, PII N1265
-
Kretschmer K, Apostolou I, Hawiger D, Khazaie K, Nussenzweig MC, von Boehmer H. Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol. 2005;6(12):1219-1227. (Pubitemid 43045633)
-
(2005)
Nature Immunology
, vol.6
, Issue.12
, pp. 1219-1227
-
-
Kretschmer, K.1
Apostolou, I.2
Hawiger, D.3
Khazaie, K.4
Nussenzweig, M.C.5
Von, B.H.6
-
4
-
-
12344307563
-
+ regulatory T cells in vivo requires B7 costimulation, but not the thymus
-
DOI 10.1084/jem.20041201
-
Liang S, Alard P, Zhao Y, Parnell S, Clark SL, Kosiewicz MM. Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus. J Exp Med. 2005;201(1):127-137. (Pubitemid 40130090)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.1
, pp. 127-137
-
-
Liang, S.1
Alard, P.2
Zhao, Y.3
Parnell, S.4
Clark, S.L.5
Kosiewicz, M.M.6
-
5
-
-
0348223787
-
+ Regulatory T Cells by TGF-beta Induction of Transcription Factor Foxp3
-
DOI 10.1084/jem.20030152
-
Chen W, Jin W, Hardegen N, et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med. 2003;198(12):1875-1886. (Pubitemid 38032120)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.12
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.-J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
6
-
-
33947644716
-
+ T regulatory cells
-
Davidson TS, Dipaolo RJ, Andersson J, Shevach EM. Cutting edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells. J Immunol. 2007;178(7):4022-4026. (Pubitemid 46492349)
-
(2007)
Journal of Immunology
, vol.178
, Issue.7
, pp. 4022-4026
-
-
Davidson, T.S.1
DiPaolo, R.J.2
Andersson, J.3
Shevach, E.M.4
-
7
-
-
2142645808
-
- T Cells through Foxp3 Induction and Down-Regulation of Smad7
-
Fantini MC, Becker C, Monteleone G, Pallone F, Galle PR, Neurath MF. Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25-T cells through Foxp3 induction and down-regulation of Smad7. J Immunol. 2004;172(9):5149-5153. (Pubitemid 38542009)
-
(2004)
Journal of Immunology
, vol.172
, Issue.9
, pp. 5149-5153
-
-
Fantini, M.C.1
Becker, C.2
Monteleone, G.3
Pallone, F.4
Galle, P.R.5
Neurath, M.F.6
-
8
-
-
33846923124
-
+ regulatory T cells and for expansion of these cells
-
Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA. IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells. J Immunol. 2007;178(4):2018-2027. (Pubitemid 46233398)
-
(2007)
Journal of Immunology
, vol.178
, Issue.4
, pp. 2018-2027
-
-
Song, G.Z.1
Wang, J.2
Wang, P.3
Gray, J.D.4
Horwitz, D.A.5
-
9
-
-
0033682056
-
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
-
Salomon B, Lenschow DJ, Rhee L, et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity. 2000;12(4):431-440.
-
(2000)
Immunity
, vol.12
, Issue.4
, pp. 431-440
-
-
Salomon, B.1
Lenschow, D.J.2
Rhee, L.3
-
10
-
-
13944260538
-
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
-
DOI 10.1038/ni1160
-
Tai X, Cowan M, Feigenbaum L, Singer A. CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2. Nat Immunol. 2005;6(2):152-162. (Pubitemid 40268196)
-
(2005)
Nature Immunology
, vol.6
, Issue.2
, pp. 152-162
-
-
Tai, X.1
Cowan, M.2
Feigenbaum, L.3
Singer, A.4
-
11
-
-
0141920662
-
+ regulatory T cells
-
Tang Q, Henriksen KJ, Boden EK, et al. Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells. J Immunol. 2003;171(7):3348-3352. (Pubitemid 37254533)
-
(2003)
Journal of Immunology
, vol.171
, Issue.7
, pp. 3348-3352
-
-
Tang, Q.1
Henriksen, K.J.2
Boden, E.K.3
Tooley, A.J.4
Ye, J.5
Subudhi, S.K.6
Zheng, X.X.7
Strom, T.B.8
Bluestone, J.A.9
-
12
-
-
11144230063
-
The CD28 family: A T-cell rheostat for therapeutic control of T-cell activation
-
Riley JL, June CH. The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation. Blood. 2005;105(1):13-21.
-
(2005)
Blood
, vol.105
, Issue.1
, pp. 13-21
-
-
Riley, J.L.1
June, C.H.2
-
13
-
-
53149114893
-
CD28 controls differentiation of regulatory T cells from naive CD4 T cells
-
Guo F, Iclozan C, Suh WK, Anasetti C, Yu XZ. CD28 controls differentiation of regulatory T cells from naive CD4 T cells. J Immunol. 2008;181(4):2285-2291.
-
(2008)
J Immunol
, vol.181
, Issue.4
, pp. 2285-2291
-
-
Guo, F.1
Iclozan, C.2
Suh, W.K.3
Anasetti, C.4
Yu, X.Z.5
-
14
-
-
34547769253
-
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
-
DOI 10.1084/jem.20070719
-
Benson MJ, Pino-Lagos K, Rosemblatt M, Noelle RJ. All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J Exp Med. 2007;204(8):1765-1774. (Pubitemid 47236315)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.8
, pp. 1765-1774
-
-
Benson, M.J.1
Pino-Lagos, K.2
Rosemblatt, M.3
Noelle, R.J.4
-
15
-
-
33746379546
-
The role of the transcription factor Foxp3 in the development of regulatory T cells
-
DOI 10.1111/j.0105-2896.2006.00426.x
-
Kim JM, Rudensky A. The role of the transcription factor Foxp3 in the development of regulatory T cells. Immunol Rev. 2006;212:86-98. (Pubitemid 44116702)
-
(2006)
Immunological Reviews
, vol.212
, pp. 86-98
-
-
Kim, J.M.1
Rudensky, A.2
-
16
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor Foxp3
-
DOI 10.1016/j.immuni.2005.01.016
-
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity. 2005;22(3):329-341. (Pubitemid 40387475)
-
(2005)
Immunity
, vol.22
, Issue.3
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
17
-
-
27544481941
-
A function for interleukin 2 in Foxp3-expressing regulatory T cells
-
DOI 10.1038/ni1263, PII N1263
-
Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol. 2005;6(11):1142-1151. (Pubitemid 41541792)
-
(2005)
Nature Immunology
, vol.6
, Issue.11
, pp. 1142-1151
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Gavin, M.A.3
Rudensky, A.Y.4
-
18
-
-
85047693292
-
CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens
-
DOI 10.1172/JCI200420940
-
Yu XZ, Albert MH, Martin PJ, Anasetti C. CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens. J Clin Invest. 2004;113(11):1624-1630. (Pubitemid 39071686)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.11
, pp. 1624-1630
-
-
Yu, X.-Z.1
Albert, M.H.2
Martin, P.J.3
Anasetti, C.4
-
19
-
-
75149118145
-
T helper17 cells are sufficient but not necessary to induce acute graft-versus-host disease
-
Iclozan C, Yu Y, Liu C, et al. T helper17 cells are sufficient but not necessary to induce acute graft-versus-host disease. Biol Blood Marrow Transplant. 2010;16(2):170-178.
-
(2010)
Biol Blood Marrow Transplant
, vol.16
, Issue.2
, pp. 170-178
-
-
Iclozan, C.1
Yu, Y.2
Liu, C.3
-
20
-
-
38349188886
-
Beta2 integrins separate graft-versus-host disease and graft-versus-leukemia effects
-
Liang Y, Liu C, Djeu JY, et al. Beta2 integrins separate graft-versus-host disease and graft-versus-leukemia effects. Blood. 2008;111(2):954-962.
-
(2008)
Blood
, vol.111
, Issue.2
, pp. 954-962
-
-
Liang, Y.1
Liu, C.2
Djeu, J.Y.3
-
21
-
-
0142259712
-
Unifying concepts in CD28, ICOS and CTLA4 co-receptor signaling
-
Rudd CE, Schneider H. Unifying concepts in CD28, ICOS and CTLA4 co-receptor signaling. Nat Rev. 2003;3(7):544-556.
-
(2003)
Nat Rev
, vol.3
, Issue.7
, pp. 544-556
-
-
Rudd, C.E.1
Schneider, H.2
-
22
-
-
67650072922
-
Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation
-
Dodson LF, Boomer JS, Deppong CM, et al. Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation. Mol Cell Biol. 2009;29(13):3710-3721.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.13
, pp. 3710-3721
-
-
Dodson, L.F.1
Boomer, J.S.2
Deppong, C.M.3
-
23
-
-
33748468629
-
A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant
-
DOI 10.1084/jem.20052230
-
Friend LD, Shah DD, Deppong C, et al. A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant. J Exp Med. 2006;203(9):2121-2133. (Pubitemid 44352233)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.9
, pp. 2121-2133
-
-
Friend, L.D.1
Shah, D.D.2
Deppong, C.3
Lin, J.4
Bricker, T.L.5
Juehne, T.I.6
Rose, C.M.7
Green, J.M.8
-
24
-
-
0035340150
-
L
-
Burr JS, Savage ND, Messah GE, et al. Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL. J Immunol. 2001;166(9):5331-5335. (Pubitemid 32374151)
-
(2001)
Journal of Immunology
, vol.166
, Issue.9
, pp. 5331-5335
-
-
Burr, J.S.1
Savage, N.D.L.2
Messah, G.E.3
Kimzey, S.L.4
Shaw, A.S.5
Arch, R.H.6
Green, J.M.7
-
25
-
-
0035869402
-
Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo
-
Harada Y, Tokushima M, Matsumoto Y, et al. Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated co-stimulation in vivo. J Immunol. 2001;166(6):3797-3803. (Pubitemid 32224904)
-
(2001)
Journal of Immunology
, vol.166
, Issue.6
, pp. 3797-3803
-
-
Harada, Y.1
Tokushima, M.2
Matsumoto, Y.3
Ogawa, S.4
Otsuka, M.5
Hayashi, K.6
Weiss, B.D.7
June, C.H.8
Abe, R.9
-
26
-
-
0035319244
-
A point mutation in CD28 distinguishes proliferative signals from survival signals
-
DOI 10.1038/86327
-
Okkenhaug K, Wu L, Garza KM, et al. A point mutation in CD28 distinguishes proliferative signals from survival signals. Nat Immunol. 2001;2(4):325-332. (Pubitemid 33706343)
-
(2001)
Nature Immunology
, vol.2
, Issue.4
, pp. 325-332
-
-
Okkenhaug, K.1
Wu, L.2
Garza, K.M.3
La, R.J.4
Khoo, W.5
Odermatt, B.6
Mak, T.W.7
Ohashi, P.S.8
Rottapel, R.9
-
28
-
-
65349151316
-
Regulating the regulators: Costimulatory signals control the homeostasis and function of regulatory T cells
-
Bour-Jordan H, Bluestone JA. Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells. Immunol Rev. 2009;229(1):41-66.
-
(2009)
Immunol Rev
, vol.229
, Issue.1
, pp. 41-66
-
-
Bour-Jordan, H.1
Bluestone, J.A.2
-
29
-
-
77952767221
-
Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development
-
Vang KB, Yang J, Pagan AJ, et al. Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development. J Immunol. 2010;184(8):4074- 4077.
-
(2010)
J Immunol
, vol.184
, Issue.8
, pp. 4074-4077
-
-
Vang, K.B.1
Yang, J.2
Pagan, A.J.3
-
30
-
-
73949090725
-
C-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells
-
Isomura I, Palmer S, Grumont RJ, et al. c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells. J Exp Med. 2009;206(13):3001-3014.
-
(2009)
J Exp Med
, vol.206
, Issue.13
, pp. 3001-3014
-
-
Isomura, I.1
Palmer, S.2
Grumont, R.J.3
-
31
-
-
71749094333
-
Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome
-
Ruan Q, Kameswaran V, Tone Y, et al. Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome. Immunity. 2009;31(6):932-940.
-
(2009)
Immunity
, vol.31
, Issue.6
, pp. 932-940
-
-
Ruan, Q.1
Kameswaran, V.2
Tone, Y.3
-
32
-
-
71749088574
-
Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor
-
Long M, Park SG, Strickland I, Hayden MS, Ghosh S. Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. Immunity. 2009;31(6):921-931.
-
(2009)
Immunity
, vol.31
, Issue.6
, pp. 921-931
-
-
Long, M.1
Park, S.G.2
Strickland, I.3
Hayden, M.S.4
Ghosh, S.5
-
33
-
-
0036195934
-
Regulation of Lck activity by CD4 and CD28 in the immunological synapse
-
DOI 10.1038/ni761
-
Holdorf AD, Lee KH, Burack WR, Allen PM, Shaw AS. Regulation of Lck activity by CD4 and CD28 in the immunological synapse. Nat Immunol. 2002;3(3):259-264. (Pubitemid 34213427)
-
(2002)
Nature Immunology
, vol.3
, Issue.3
, pp. 259-264
-
-
Holdorf, A.D.1
Lee, K.-H.2
Burack, W.R.3
Allen, P.M.4
Shaw, A.S.5
-
34
-
-
77955391804
-
TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
-
Gottschalk RA, Corse E, Allison JP. TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo. J Exp Med. 2010;207(8):1701- 1711.
-
(2010)
J Exp Med
, vol.207
, Issue.8
, pp. 1701-1711
-
-
Gottschalk, R.A.1
Corse, E.2
Allison, J.P.3
-
35
-
-
0033613826
-
T lymphocyte costimulation mediated by reorganization of membrane microdomains
-
Viola A, Schroeder S, Sakakibara Y, Lanzavecchia A. T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science. 1999;283(5402):680-682.
-
(1999)
Science
, vol.283
, Issue.5402
, pp. 680-682
-
-
Viola, A.1
Schroeder, S.2
Sakakibara, Y.3
Lanzavecchia, A.4
-
36
-
-
0037443420
-
CD28 signal enhances apoptosis of CD8 T cells after strong TCR ligation
-
Yu XZ, Martin PJ, Anasetti C. CD28 signal enhances apoptosis of CD8 T cells after strong TCR ligation. J Immunol. 2003;170(6):3002-3006. (Pubitemid 36302173)
-
(2003)
Journal of Immunology
, vol.170
, Issue.6
, pp. 3002-3006
-
-
Yu, X.-Z.1
Martin, P.J.2
Anasetti, C.3
-
37
-
-
72449172451
-
Paradoxical functions of B7: CD28 costimulation in a MHC class II-mismatched cardiac transplant model
-
Yang J, Riella LV, Boenisch O, et al. Paradoxical functions of B7: CD28 costimulation in a MHC class II-mismatched cardiac transplant model. Am J Transplant. 2009;9(12):2837-2844.
-
(2009)
Am J Transplant
, vol.9
, Issue.12
, pp. 2837-2844
-
-
Yang, J.1
Riella, L.V.2
Boenisch, O.3
|