-
1
-
-
0034651823
-
Bacterial toxins with intracellular protease activity
-
DOI 10.1016/S0009-8981(99)00228-4, PII S0009898199002284
-
Rossetto, O.; de Bernard, M.; Pellizzari, R.; Vitale, G.; Caccin, P.; Schiavo, G.; Montecucco, C. Bacterial toxins with intracellular protease activity. Clin. Chim. Acta 2000, 291, 189-199. (Pubitemid 30089764)
-
(2000)
Clinica Chimica Acta
, vol.291
, Issue.2
, pp. 189-199
-
-
Rossetto, O.1
De Bernard, M.2
Pellizzari, R.3
Vitale, G.4
Caccin, P.5
Schiavo, G.6
Montecucco, C.7
-
2
-
-
33846906495
-
Contribution of toxins to the pathogenesis of inhalational anthrax
-
DOI 10.1111/j.1462-5822.2006.00866.x
-
Tournier, J.N.; Quesnel-Hellmann, A.; Cleret, A.; Vidal, D.R. Contribution of toxins to the pathogenesis of inhalational anthrax. Cell Microbiol. 2007, 9, 555-565. (Pubitemid 46231963)
-
(2007)
Cellular Microbiology
, vol.9
, Issue.3
, pp. 555-565
-
-
Tournier, J.-N.1
Quesnel-Hellmann, A.2
Cleret, A.3
Vidal, D.R.4
-
3
-
-
21644452600
-
From the mouse to the mass spectrometer: Detection and differentiation of the endoproteinase activities of botulinum neurotoxins A-G by mass spectrometry
-
DOI 10.1021/ac050485f
-
Boyer, A.E.; Moura, H.; Woolfitt, A.R.; Kalb, S.R.; McWilliams, L.G.; Pavlopoulos, A.; Schmidt, J.G.; Ashley, D.L.; Barr, J.R. From the mouse to the mass spectrometer: Detection and differentiation of the endoproteinase activities of botulinum neurotoxins A-G by mass spectrometry. Anal. Chem. 2005, 77, 3916-3924. (Pubitemid 40934253)
-
(2005)
Analytical Chemistry
, vol.77
, Issue.13
, pp. 3916-3924
-
-
Boyer, A.E.1
Moura, H.2
Woolfitt, A.R.3
Kalb, S.R.4
McWilliams, L.G.5
Pavlopoulos, A.6
Schmidt, J.G.7
Ashley, D.L.8
Barr, J.R.9
-
4
-
-
33644933631
-
The use of Endopep-MS for the detection of botulinum toxins A, B, E, and F in serum and stool samples
-
Kalb, S.R.; Moura, H.; Boyer, A.E.; McWilliams, L.G.; Pirkle, J.L.; Barr, J.R. The use of Endopep-MS for the detection of botulinum toxins A, B, E, and F in serum and stool samples. Anal. Biochem. 2006, 351, 84-92.
-
(2006)
Anal. Biochem.
, vol.351
, pp. 84-92
-
-
Kalb, S.R.1
Moura, H.2
Boyer, A.E.3
McWilliams, L.G.4
Pirkle, J.L.5
Barr, J.R.6
-
5
-
-
65449127764
-
Extraction and inhibition of enzymatic activity of botulinum neurotoxins/A1, /A2, and /A3 by a panel of monoclonal anti-BoNT/A antibodies
-
Kalb, S.R.; Lou, J.; Garcia-Rodriguez, C.; Geren, I.N.; Smith, T.J.; Moura, H.; Marks, J.D.; Smith, L.A.; Pirkle, J.L.; Barr, J.R. Extraction and inhibition of enzymatic activity of botulinum neurotoxins/A1, /A2, and /A3 by a panel of monoclonal anti-BoNT/A antibodies. PLoS One 2009, 4, e5355.
-
(2009)
PLoS One
, vol.4
-
-
Kalb, S.R.1
Lou, J.2
Garcia-Rodriguez, C.3
Geren, I.N.4
Smith, T.J.5
Moura, H.6
Marks, J.D.7
Smith, L.A.8
Pirkle, J.L.9
Barr, J.R.10
-
6
-
-
67651227332
-
Kinetics of lethal factor and poly-D-glutamic acid antigenemia during inhalation anthrax in rhesus macaques
-
Boyer, A.E.; Quinn, C.P.; Hoffmaster, A.R.; Kozel, T.R.; Saile, E.; Marston, C.K.; Percival, A.; Plikaytis, B.D.; Woolfitt, A.R.; Gallegos, M.; Sabourin, P.; McWilliams, L.G.; Pirkle, J.L.; Barr, J.R. Kinetics of lethal factor and poly-D-glutamic acid antigenemia during inhalation anthrax in rhesus macaques. Infect. Immun. 2009, 77, 3432-3441.
-
(2009)
Infect. Immun.
, vol.77
, pp. 3432-3441
-
-
Boyer, A.E.1
Quinn, C.P.2
Hoffmaster, A.R.3
Kozel, T.R.4
Saile, E.5
Marston, C.K.6
Percival, A.7
Plikaytis, B.D.8
Woolfitt, A.R.9
Gallegos, M.10
Sabourin, P.11
McWilliams, L.G.12
Pirkle, J.L.13
Barr, J.R.14
-
7
-
-
36448970546
-
Detection and quantification of anthrax lethal factor in serum by mass spectrometry
-
DOI 10.1021/ac701741s
-
Boyer, A.E.; Quinn, C.P.; Woolfitt, A.R.; Pirkle, J.L.; McWilliams, L.G.; Stamey, K.L.; Bagarozzi, D.A.; Hart, J.C., Jr.; Barr, J.R. Detection and quantification of anthrax lethal factor in serum by mass spectrometry. Anal. Chem. 2007, 79, 8463-8470. (Pubitemid 350171353)
-
(2007)
Analytical Chemistry
, vol.79
, Issue.22
, pp. 8463-8470
-
-
Boyer, A.E.1
Quinn, C.P.2
Woolfitt, A.R.3
Pirkle, J.L.4
McWilliams, L.G.5
Stamey, K.L.6
Bagarozzi, D.A.7
Hart Jr., J.C.8
Barr, J.R.9
-
8
-
-
0033611703
-
Tetanus and botulinum neurotoxins: Mechanism of action and therapeutic uses
-
Pellizzari, R.; Rossetto, O.; Schiavo, G.; Montecucco, C. Tetanus and botulinum neurotoxins: Mechanism of action and therapeutic uses. Philos. Trans. R. Soc. Lond. B Biol. Sci. 1999, 354, 259-268. (Pubitemid 29365599)
-
(1999)
Philosophical Transactions of the Royal Society B: Biological Sciences
, vol.354
, Issue.1381
, pp. 259-268
-
-
Pellizzari, R.1
Rossetto, O.2
Schiavo, G.3
Montecucco, C.4
-
9
-
-
33846598840
-
Genetic diversity among botulinum neurotoxin-producing clostridial strains
-
DOI 10.1128/JB.01180-06
-
Hill, K.K.; Smith, T.J.; Helma, C.H.; Ticknor, L.O.; Foley, B.T.; Svensson, R.T.; Brown, J.L.; Johnson, E.A.; Smith, L.A.; Okinaka, R.T.; Jackson, P.J.; Marks, J.D. Genetic diversity among Botulinum Neurotoxin-producing clostridial strains. J. Bacteriol. 2007, 189, 818-832. (Pubitemid 46183856)
-
(2007)
Journal of Bacteriology
, vol.189
, Issue.3
, pp. 818-832
-
-
Hill, K.K.1
Smith, T.J.2
Helma, C.H.3
Ticknor, L.O.4
Foley, B.T.5
Svensson, R.T.6
Brown, J.L.7
Johnson, E.A.8
Smith, L.A.9
Okinaka, R.T.10
Jackson, P.J.11
Marks, J.D.12
-
10
-
-
0034018885
-
Neurotoxins affecting neuroexocytosis
-
Schiavo, G.; Matteoli, M.; Montecucco, C. Neurotoxins affecting neuroexocytosis. Physiol. Rev. 2000, 80, 717-766. (Pubitemid 30164948)
-
(2000)
Physiological Reviews
, vol.80
, Issue.2
, pp. 717-766
-
-
Schiavo, G.1
Matteoli, M.2
Montecucco, C.3
-
11
-
-
0029954333
-
Mosaic structures of neurotoxins produced from Clostridium botulinum types C and D organisms
-
Moriishi, K.; Koura, M.; Abe, N.; Fujii, N.; Fujinaga, Y.; Inoue, K.; Ogumad, K. Mosaic structures of neurotoxins produced from Clostridium botulinum types C and D organisms. Biochim. Biophys. Acta 1996, 1307, 123-126.
-
(1996)
Biochim. Biophys. Acta
, vol.1307
, pp. 123-126
-
-
Moriishi, K.1
Koura, M.2
Abe, N.3
Fujii, N.4
Fujinaga, Y.5
Inoue, K.6
Ogumad, K.7
-
12
-
-
79952629403
-
Studies on Botulinum Neurotoxins Type /C1 and mosaic /DC Using Endopep-MS and Proteomics
-
in press
-
Moura, H.T.R.; Woolfitt, A.R.; Gallegos-Candela, M.; McWilliams, L.G.; Solano, M.I.; Pirkle, J.L.; Barr, J.R. Studies on Botulinum Neurotoxins Type /C1 and mosaic /DC Using Endopep-MS and Proteomics. FEMS Immunol. Microbiol. 2011, in press.
-
(2011)
FEMS Immunol. Microbiol.
-
-
Moura, H.T.R.1
Woolfitt, A.R.2
Gallegos-Candela, M.3
McWilliams, L.G.4
Solano, M.I.5
Pirkle, J.L.6
Barr, J.R.7
-
13
-
-
23944472235
-
Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralization
-
DOI 10.1128/IAI.73.9.5450-5457.2005
-
Smith, T.J.; Lou, J.; Geren, I.N.; Forsyth, C.M.; Tsai, R.; Laporte, S.L.; Tepp, W.H.; Bradshaw, M.; Johnson, E.A.; Smith, L.A.; Marks, J.D. Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralization. Infect. Immun. 2005, 73, 5450-5457. (Pubitemid 41192979)
-
(2005)
Infection and Immunity
, vol.73
, Issue.9
, pp. 5450-5457
-
-
Smith, T.J.1
Lou, J.2
Geren, I.N.3
Forsyth, C.M.4
Tsai, R.5
LaPorte, S.L.6
Tepp, W.H.7
Bradshaw, M.8
Johnson, E.A.9
Smith, L.A.10
Marks, J.D.11
-
14
-
-
0037238128
-
Anthrax toxins and the host: A story of intimacy
-
DOI 10.1046/j.1462-5822.2003.00253.x
-
Mock, M.; Mignot, T. Anthrax toxins and the host: A story of intimacy. Cell Microbiol. 2003, 5, 15-23. (Pubitemid 36395117)
-
(2003)
Cellular Microbiology
, vol.5
, Issue.1
, pp. 15-23
-
-
Mock, M.1
Mignot, T.2
-
15
-
-
33947256514
-
Manipulation of host signalling pathways by anthrax toxins
-
DOI 10.1042/BJ20061891
-
Turk, B.E. Manipulation of host signalling pathways by anthrax toxins. Biochem. J. 2007, 402, 405-417. (Pubitemid 46423878)
-
(2007)
Biochemical Journal
, vol.402
, Issue.3
, pp. 405-417
-
-
Turk, B.E.1
-
16
-
-
0026498189
-
Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin
-
Klimpel, K.R.; Molloy, S.S.; Thomas, G.; Leppla, S.H. Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin. Proc. Natl. Acad. Sci. USA 1992, 89, 10277-10281.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10277-10281
-
-
Klimpel, K.R.1
Molloy, S.S.2
Thomas, G.3
Leppla, S.H.4
-
17
-
-
0026775916
-
Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
-
Molloy, S.S.; Bresnahan, P.A.; Leppla, S.H.; Klimpel, K.R.; Thomas, G. Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J. Biol. Chem. 1992, 267, 16396-16402.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 16396-16402
-
-
Molloy, S.S.1
Bresnahan, P.A.2
Leppla, S.H.3
Klimpel, K.R.4
Thomas, G.5
-
18
-
-
69349098830
-
The protective antigen component of anthrax toxin forms functional octameric complexes
-
Kintzer, A.F.; Thoren, K.L.; Sterling, H.J.; Dong, K.C.; Feld, G.K.; Tang, II; Zhang, T.T.; Williams, E.R.; Berger, J.M.; Krantz, B.A. The protective antigen component of anthrax toxin forms functional octameric complexes. J. Mol. Biol. 2009, 392, 614-629.
-
(2009)
J. Mol. Biol.
, vol.392
, pp. 614-629
-
-
Kintzer, A.F.1
Thoren, K.L.2
Sterling, H.J.3
Dong, K.C.4
Feld, G.K.5
Tang, I.I.6
Zhang, T.T.7
Williams, E.R.8
Berger, J.M.9
Krantz, B.A.10
-
19
-
-
19544371576
-
Anthrax lethal toxin induces endothelial barrier dysfunction
-
Warfel, J.M.; Steele, A.D.; D'Agnillo, F. Anthrax lethal toxin induces endothelial barrier dysfunction. Am. J. Pathol. 2005, 166, 1871-1881. (Pubitemid 40734409)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.6
, pp. 1871-1881
-
-
Warfel, J.M.1
Steele, A.D.2
D'Agnillo, F.3
-
20
-
-
78650395903
-
Anthrax lethal and edema toxins produce different patterns of cardiovascular and renal dysfunction and synergistically decrease survival in canines
-
Sweeney, D.A.; Cui, X.; Solomon, S.B.; Vitberg, D.A.; Migone, T.S.; Scher, D.; Danner, R.L.; Natanson, C.; Subramanian, G.M.; Eichacker, P.Q. Anthrax lethal and edema toxins produce different patterns of cardiovascular and renal dysfunction and synergistically decrease survival in canines. J. Infect. Dis. 2010, 202, 1885-1896.
-
(2010)
J. Infect. Dis.
, vol.202
, pp. 1885-1896
-
-
Sweeney, D.A.1
Cui, X.2
Solomon, S.B.3
Vitberg, D.A.4
Migone, T.S.5
Scher, D.6
Danner, R.L.7
Natanson, C.8
Subramanian, G.M.9
Eichacker, P.Q.10
-
21
-
-
79953090499
-
Association of early lethal factor levels with survival during inhalation anthrax in rhesus macaques
-
American Society for Microbiology: Washington DC, USA
-
Boyer, A.E.; Quinn, C.P.; Hoffmaster, A.R.; Kozel, T.; Gallegos, M.; Saile, E.; Marston, C.; Beesley, C.; Percival, A.; Lins, R.; Woolfitt, A.; Pirkle, J.L.; Barr, J.R. Association of Early Lethal Factor Levels with Survival during Inhalation Anthrax in Rhesus Macaques. In Proceedings of ASM Biodefense and Emerging Diseases Research Meeting, Baltimore, MD, USA, 6-9 February 2010; American Society for Microbiology: Washington, DC, USA, 2010.
-
(2010)
Proceedings of ASM Biodefense and Emerging Diseases Research Meeting, Baltimore, MD, USA, 6-9 February 2010
-
-
Boyer, A.E.1
Quinn, C.P.2
Hoffmaster, A.R.3
Kozel, T.4
Gallegos, M.5
Saile, E.6
Marston, C.7
Beesley, C.8
Percival, A.9
Lins, R.10
Woolfitt, A.11
Pirkle, J.L.12
Barr, J.R.13
-
22
-
-
33947390946
-
A case of naturally acquired inhalation anthrax: Clinical care and analyses of anti-protective antigen immunoglobulin G and lethal factor
-
DOI 10.1086/512372
-
Walsh, J.J.; Pesik, N.; Quinn, C.P.; Urdaneta, V.; Dykewicz, C.A.; Boyer, A.E.; Guarner, J.; Wilkins, P.; Norville, K.J.; Barr, J.R.; Zaki, S.R.; Patel, J.B.; Reagan, S.P.; Pirkle, J.L.; Treadwell, T.A.; Messonnier, N.R.; Rotz, L.D.; Meyer, R.F.; Stephens, D.S. A case of naturally acquired inhalation anthrax: Clinical care and analyses of anti-protective antigen immunoglobulin G and lethal factor. Clin. Infect. Dis. 2007, 44, 968-971. (Pubitemid 46452063)
-
(2007)
Clinical Infectious Diseases
, vol.44
, Issue.7
, pp. 968-971
-
-
Walsh, J.J.1
Pesik, N.2
Quinn, C.P.3
Urdaneta, V.4
Dykewicz, C.A.5
Boyer, A.E.6
Guarner, J.7
Wilkins, P.8
Norville, K.J.9
Barr, J.R.10
Zaki, S.R.11
Patel, J.B.12
Reagan, S.P.13
Pirkle, J.L.14
Treadwell, T.A.15
Messonnier, N.R.16
Rotz, L.D.17
Meyer, R.F.18
Stephens, D.S.19
-
23
-
-
0037360157
-
Detection of botulinal neurotoxins A, B, E, and F by amplified enzyme-linked immunosorbent assay: Collaborative study
-
Ferreira, J.L.; Maslanka, S.; Johnson, E.; Goodnough, M. Detection of botulinal neurotoxins A, B, E, and F by amplified enzyme-linked immunosorbent assay: Collaborative study. J. AOAC Int. 2003, 86, 314-331.
-
(2003)
J. AOAC Int.
, vol.86
, pp. 314-331
-
-
Ferreira, J.L.1
Maslanka, S.2
Johnson, E.3
Goodnough, M.4
-
24
-
-
0026587409
-
Serum protease cleavage of Bacillus anthracis protective antigen
-
Ezzell, J.W., Jr.; Abshire, T.G. Serum protease cleavage of Bacillus anthracis protective antigen. J. Gen. Microbiol. 1992, 138, 543-549.
-
(1992)
J. Gen. Microbiol.
, vol.138
, pp. 543-549
-
-
Ezzell Jr., J.W.1
Abshire, T.G.2
-
25
-
-
20144383121
-
Purified Bacillus anthracis lethal toxin complex formed in vitro and during infection exhibits functional and biological activity
-
DOI 10.1074/jbc.M412210200
-
Panchal, R.G.; Halverson, K.M.; Ribot, W.; Lane, D.; Kenny, T.; Abshire, T.G.; Ezzell, J.W.; Hoover, T.A.; Powell, B.; Little, S.; Kasianowicz, J.J.; Bavari, S. Purified Bacillus anthracis lethal toxin complex formed in vitro and during infection exhibits functional and biological activity. J. Biol. Chem. 2005, 280, 10834-10839. (Pubitemid 40395947)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.11
, pp. 10834-10839
-
-
Panchal, R.G.1
Halverson, K.M.2
Ribot, W.3
Lane, D.4
Kenny, T.5
Abshire, T.G.6
Ezzell, J.W.7
Hoover, T.A.8
Powell, B.9
Little, S.10
Kasianowicz, J.J.11
Bavari, S.12
-
26
-
-
10244256354
-
Isotope dilution-mass spectrometric quantification of specific proteins: Model application with apolipoprotein A-I
-
Barr, J.R.; Maggio, V.L.; Patterson, D.G., Jr.; Cooper, G.R.; Henderson, L.O.; Turner, W.E.; Smith, S.J.; Hannon, W.H.; Needham, L.L.; Sampson, E.J. Isotope dilution-mass spectrometric quantification of specific proteins: Model application with apolipoprotein A-I. Clin. Chem. 1996, 42, 1676-1682. (Pubitemid 26354748)
-
(1996)
Clinical Chemistry
, vol.42
, Issue.10
, pp. 1676-1682
-
-
Barr, J.R.1
Maggio, V.L.2
Patterson Jr., D.G.3
Cooper, G.R.4
Henderson, L.O.5
Turner, W.E.6
Smith, S.J.7
Hannon, W.H.8
Needham, L.L.9
Sampson, E.J.10
-
27
-
-
42649130016
-
Quantification of influenza virus hemagglutinins in complex mixtures using isotope dilution tandem mass spectrometry
-
Williams, T.L.; Luna, L.; Guo, Z.; Cox, N.J.; Pirkle, J.L.; Donis, R.O.; Barr, J.R. Quantification of influenza virus hemagglutinins in complex mixtures using isotope dilution tandem mass spectrometry. Vaccine 2008, 26, 2510-2520.
-
(2008)
Vaccine
, vol.26
, pp. 2510-2520
-
-
Williams, T.L.1
Luna, L.2
Guo, Z.3
Cox, N.J.4
Pirkle, J.L.5
Donis, R.O.6
Barr, J.R.7
-
28
-
-
79952163192
-
Comparison of MALDI-TOF-MS and HPLC-ESI-MS/MS for endopeptidase activity based quantification of anthrax lethal factor in serum
-
in press
-
Kuklenyik, Z.; Boyer, A.E.; Lins, R.; Quinn, C.P.; Gallegos-Candela, M.; Woolfitt, A.R.; Pirkle, J.L.; Barr, J.R. Comparison of MALDI-TOF-MS and HPLC-ESI-MS/MS for Endopeptidase Activity Based Quantification of Anthrax Lethal Factor in Serum. Anal. Chem. 2011, in press.
-
(2011)
Anal. Chem.
-
-
Kuklenyik, Z.1
Boyer, A.E.2
Lins, R.3
Quinn, C.P.4
Gallegos-Candela, M.5
Woolfitt, A.R.6
Pirkle, J.L.7
Barr, J.R.8
-
29
-
-
79953124904
-
-
Salt Lake City, UT, USA 23-27 May 2010; American Society for Mass Spectrometry: Santa Fe, NM, USA
-
Lins, R.C.; Boyer, A.E.; Kuklenyik, Z.; Quinn, C.P.; Gallegos-Candela, M.; Leysath, C.E.; Chen, Z.; Chen, K.; Makiya, M.; Leppla, S.H.; Pirkle, J.L.; Barr, J.R. In A High Sensitivity Adenylate Cyclase Assay for Anthrax Edema factor., Proceedings of 58th ASMS Conference on Mass Spectrometry and Allied Topics, Salt Lake City, UT, USA, 23-27 May 2010; American Society for Mass Spectrometry: Santa Fe, NM, USA, 2010.
-
(2010)
A High Sensitivity Adenylate Cyclase Assay for Anthrax Edema factor., Proceedings of 58th ASMS Conference on Mass Spectrometry and Allied Topics
-
-
Lins, R.C.1
Boyer, A.E.2
Kuklenyik, Z.3
Quinn, C.P.4
Gallegos-Candela, M.5
Leysath, C.E.6
Chen, Z.7
Chen, K.8
Makiya, M.9
Leppla, S.H.10
Pirkle, J.L.11
Barr, J.R.12
-
30
-
-
0347192782
-
The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor
-
DOI 10.1038/nsmb708
-
Turk, B.E.; Wong, T.Y.; Schwarzenbacher, R.; Jarrell, E.T.; Leppla, S.H.; Collier, R.J.; Liddington, R.C.; Cantley, L.C. The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat. Struct. Mol. Biol. 2004, 11, 60-66. (Pubitemid 38173442)
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.1
, pp. 60-66
-
-
Turk, B.E.1
Wong, T.Y.2
Schwarzenbacher, R.3
Jarrell, E.T.4
Leppla, S.H.5
Collier, R.J.6
Liddington, R.C.7
Cantley, L.C.8
-
31
-
-
0032755353
-
Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha
-
Pellizzari, R.; Guidi-Rontani, C.; Vitale, G.; Mock, M.; Montecucco, C. Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha. FEBS Lett. 1999, 462, 199-204.
-
(1999)
FEBS Lett.
, vol.462
, pp. 199-204
-
-
Pellizzari, R.1
Guidi-Rontani, C.2
Vitale, G.3
Mock, M.4
Montecucco, C.5
-
32
-
-
18244414803
-
Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor
-
DOI 10.1126/science.280.5364.734
-
Duesbery, N.S.; Webb, C.P.; Leppla, S.H.; Gordon, V.M.; Klimpel, K.R.; Copeland, T.D.; Ahn, N.G.; Oskarsson, M.K.; Fukasawa, K.; Paull, K.D.; Vande Woude, G.F. Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science 1998, 280, 734-737. (Pubitemid 28243347)
-
(1998)
Science
, vol.280
, Issue.5364
, pp. 734-737
-
-
Duesbery, N.S.1
Webb, C.P.2
Leppla, S.H.3
Gordon, V.M.4
Klimpel, K.R.5
Copeland, T.D.6
Ahn, N.G.7
Oskarsson, M.K.8
Fukasawa, K.9
Paull, K.D.10
Vande Woude, G.F.11
-
33
-
-
0034672216
-
Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor
-
DOI 10.1042/0264-6021:3520739
-
Vitale, G.; Bernardi, L.; Napolitani, G.; Mock, M.; Montecucco, C. Susceptibility of mitogenactivated protein kinase kinase family members to proteolysis by anthrax lethal factor. Biochem. J. 2000, 352 (Pt. 3), 739-745. (Pubitemid 32015030)
-
(2000)
Biochemical Journal
, vol.352
, Issue.3
, pp. 739-745
-
-
Vitale, G.1
Bernardi, L.2
Napolitani, G.3
Mock, M.4
Montecucco, C.5
-
34
-
-
3142662017
-
Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate
-
DOI 10.1074/jbc.M402689200
-
Guo, Q.; Shen, Y.; Zhukovskaya, N.L.; Florian, J.; Tang, W.J. Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate. J. Biol. Chem. 2004, 279, 29427-29435. (Pubitemid 38915822)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.28
, pp. 29427-29435
-
-
Guo, Q.1
Shen, Y.2
Zhukovskaya, N.L.3
Florian, J.4
Tang, W.-J.5
-
35
-
-
17444366186
-
Clostridium difficile toxins: Mechanism of action and role in disease
-
DOI 10.1128/CMR.18.2.247-263.2005
-
Voth, D.E.; Ballard, J.D. Clostridium difficile toxins: Mechanism of action and role in disease. Clin. Microbiol. Rev. 2005, 18, 247-263. (Pubitemid 40548293)
-
(2005)
Clinical Microbiology Reviews
, vol.18
, Issue.2
, pp. 247-263
-
-
Voth, D.E.1
Ballard, J.D.2
-
36
-
-
33947260554
-
Rho-glucosylating Clostridium difficile toxins A and B: New insights into structure and function
-
DOI 10.1093/glycob/cwm004
-
Jank, T.; Giesemann, T.; Aktories, K. Rho-glucosylating Clostridium difficile toxins A and B: new insights into structure and function. Glycobiology 2007, 17, 15R-22R. (Pubitemid 46432006)
-
(2007)
Glycobiology
, vol.17
, Issue.4
-
-
Jank, T.1
Giesemann, T.2
Aktories, K.3
-
37
-
-
0000947082
-
Anthrax toxin edema factor: A bacterial adenylate cyclase that increases cyclic AMP concentrations in eukaryotic cells
-
DOI 10.1073/pnas.79.10.3162
-
Leppla, S.H. Anthrax toxin edema factor: A bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proc. Natl. Acad. Sci. USA 1982, 79, 3162-3166. (Pubitemid 12008374)
-
(1982)
Proceedings of the National Academy of Sciences of the United States of America
, vol.79
, Issue.10
, pp. 3162-3166
-
-
Leppla, S.H.1
-
38
-
-
79953097196
-
Validation of rapid, sensitive, quantitative maldi-tof ms assays for anthrax lethal factor and lethal toxin, bacillus-ACT 2009
-
B. Cereus, and B. Thuringiensis Conference, Santa Fe, NM, USA, 30 August-3 September, 2009; American Society for Microbiology: Washington DC, USA
-
Gallegos-Candela, M.; Boyer, A.E.; Quinn, C.P.; Woolfitt, A.R.; Barr, J.R. Validation of Rapid, Sensitive, Quantitative MALDI-TOF MS Assays for Anthrax Lethal Factor and Lethal Toxin, Bacillus-ACT 2009. In Proceedings of the International Bacillus Anthracis, B. Cereus, and B. Thuringiensis Conference, Santa Fe, NM, USA, 30 August-3 September, 2009; American Society for Microbiology: Washington, DC, USA, 2009.
-
(2009)
Proceedings of the International Bacillus Anthracis
-
-
Gallegos-Candela, M.1
Boyer, A.E.2
Quinn, C.P.3
Woolfitt, A.R.4
Barr, J.R.5
-
39
-
-
33749265873
-
Protective antigen as a correlative marker for anthrax in animal models
-
DOI 10.1128/IAI.00792-06
-
Kobiler, D.; Weiss, S.; Levy, H.; Fisher, M.; Mechaly, A.; Pass, A.; Altboum, Z. Protective antigen as a correlative marker for anthrax in animal models. Infect. Immun. 2006, 74, 5871-5876. (Pubitemid 44484574)
-
(2006)
Infection and Immunity
, vol.74
, Issue.10
, pp. 5871-5876
-
-
Kobiler, D.1
Weiss, S.2
Levy, H.3
Fisher, M.4
Mechaly, A.5
Pass, A.6
Altboum, Z.7
-
40
-
-
33745856268
-
Detection of anthrax toxin in the serum of animals infected with Bacillus anthracis by using engineered immunoassays
-
DOI 10.1128/CVI.00023-06
-
Mabry, R.; Brasky, K.; Geiger, R.; Carrion, R., Jr.; Hubbard, G.B.; Leppla, S.; Patterson, J.L.; Georgiou, G.; Iverson, B.L. Detection of anthrax toxin in the serum of animals infected with Bacillus anthracis by using engineered immunoassays. Clin. Vaccine Immunol. 2006, 13, 671-677. (Pubitemid 44032513)
-
(2006)
Clinical and Vaccine Immunology
, vol.13
, Issue.6
, pp. 671-677
-
-
Mabry, R.1
Brasky, K.2
Geiger, R.3
Carrion Jr., R.4
Hubbard, G.B.5
Leppla, S.6
Patterson, J.L.7
Georgiou, G.8
Iverson, B.L.9
-
41
-
-
77957876488
-
Extraction of BoNT/A, /B, /E, and /F with a single, high affinity monoclonal antibody for detection of botulinum neurotoxin by Endopep-MS
-
Kalb, S.R.; Garcia-Rodriguez, C.; Lou, J.; Baudys, J.; Smith, T.J.; Marks, J.D.; Smith, L.A.; Pirkle, J.L.; Barr, J.R. Extraction of BoNT/A, /B, /E, and /F with a single, high affinity monoclonal antibody for detection of botulinum neurotoxin by Endopep-MS. PLoS One 2010, 5, e12237.
-
(2010)
PLoS One
, vol.5
-
-
Kalb, S.R.1
Garcia-Rodriguez, C.2
Lou, J.3
Baudys, J.4
Smith, T.J.5
Marks, J.D.6
Smith, L.A.7
Pirkle, J.L.8
Barr, J.R.9
-
42
-
-
61949129575
-
Detection of anthrax toxin by an ultrasensitive immunoassay using europium nanoparticles
-
Tang, S.; Moayeri, M.; Chen, Z.; Harma, H.; Zhao, J.; Hu, H.; Purcell, R.H.; Leppla, S.H.; Hewlett, I.K. Detection of anthrax toxin by an ultrasensitive immunoassay using europium nanoparticles. Clin. Vaccine Immunol. 2009, 16, 408-413.
-
(2009)
Clin. Vaccine Immunol.
, vol.16
, pp. 408-413
-
-
Tang, S.1
Moayeri, M.2
Chen, Z.3
Harma, H.4
Zhao, J.5
Hu, H.6
Purcell, R.H.7
Leppla, S.H.8
Hewlett, I.K.9
-
43
-
-
79953068445
-
Kinetics of toxemia of inhalation anthrax
-
Baltimore, MD, USA 24-27 February 2008; American Society for Microbiology: Washington DC, USA
-
Boyer, A.E.; Quinn, C.P.; Hoffmaster, A.; Gallegos, M.; Saile, E.; Marston, C.; Kozel, T.; Meister, G.; Woolfitt, A.R.; Pirkle, J.L.; Barr, J.R. Kinetics of Toxemia of Inhalation Anthrax. In Proceedings of 6th Annual ASM Biodefense and Emerging Diseases Research Meeting, Baltimore, MD, USA, 24-27 February 2008; American Society for Microbiology: Washington, DC, USA, 2008.
-
(2008)
Proceedings of 6th Annual ASM Biodefense and Emerging Diseases Research Meeting
-
-
Boyer, A.E.1
Quinn, C.P.2
Hoffmaster, A.3
Gallegos, M.4
Saile, E.5
Marston, C.6
Kozel, T.7
Meister, G.8
Woolfitt, A.R.9
Pirkle, J.L.10
Barr, J.R.11
-
44
-
-
26444605032
-
Detection of botulinum neurotoxin A in a spiked milk sample with subtype identification through toxin proteomics
-
DOI 10.1021/ac0511748
-
Kalb, S.R.; Goodnough, M.C.; Malizio, C.J.; Pirkle, J.L.; Barr, J.R. Detection of botulinum neurotoxin A in a spiked milk sample with subtype identification through toxin proteomics. Anal. Chem. 2005, 77, 6140-6146. (Pubitemid 41436946)
-
(2005)
Analytical Chemistry
, vol.77
, Issue.19
, pp. 6140-6146
-
-
Kalb, S.R.1
Goodnough, M.C.2
Malizio, C.J.3
Pirkle, J.L.4
Barr, J.R.5
-
45
-
-
55049106317
-
Biological monitoring of exposure to botulinum neurotoxins
-
Barr, J.R.; Kalb, S.R.; Moura, H.; Pirkle, J.L. Biological Monitoring of Exposure to Botulinum Neurotoxins. Chem. Health Safety 2008, 15, 14-19.
-
(2008)
Chem. Health Safety
, vol.15
, pp. 14-19
-
-
Barr, J.R.1
Kalb, S.R.2
Moura, H.3
Pirkle, J.L.4
-
46
-
-
59449095623
-
Measuring the severity of Clostridium difficile infection: Implications for management and drug development
-
Belmares, J.; Gerding, D.N.; Tillotson, G.; Johnson, S. Measuring the severity of Clostridium difficile infection: Implications for management and drug development. Expert Rev. Anti Infect. Ther. 2008, 6, 897-908.
-
(2008)
Expert Rev. Anti Infect. Ther.
, vol.6
, pp. 897-908
-
-
Belmares, J.1
Gerding, D.N.2
Tillotson, G.3
Johnson, S.4
-
47
-
-
39749155808
-
Do fluoroquinolones predispose patients to Clostridium difficile associated disease? A review of the evidence
-
DOI 10.1185/030079908X253735
-
Deshpande, A.; Pant, C.; Jain, A.; Fraser, T.G.; Rolston, D.D. Do fluoroquinolones predispose patients to Clostridium difficile associated disease? A review of the evidence. Curr. Med. Res. Opin. 2008, 24, 329-333. (Pubitemid 351294381)
-
(2008)
Current Medical Research and Opinion
, vol.24
, Issue.2
, pp. 329-333
-
-
Deshpande, A.1
Pant, C.2
Jain, A.3
Fraser, T.G.4
Rolston, D.D.K.5
-
48
-
-
0033016046
-
Changing epidemiology of pertussis in the United States: Increasing reported incidence among adolescents and adults, 1990-1996
-
Guris, D.; Strebel, P.M.; Bardenheier, B.; Brennan, M.; Tachdjian, R.; Finch, E.; Wharton, M.; Livengood, J.R. Changing epidemiology of pertussis in the United States: Increasing reported incidence among adolescents and adults, 1990-1996. Clin. Infect. Dis. 1999, 28, 1230-1237. (Pubitemid 29272795)
-
(1999)
Clinical Infectious Diseases
, vol.28
, Issue.6
, pp. 1230-1237
-
-
Guris, D.1
Strebel, P.M.2
Bardenheier, B.3
Brennan, M.4
Tachdjian, R.5
Finch, E.6
Wharton, M.7
Livengood, J.R.8
-
49
-
-
48249138107
-
Comparative genomic profiling of Dutch clinical Bordetella pertussis isolates using DNA microarrays: Identification of genes absent from epidemic strains
-
King, A.J.; van Gorkom, T.; Pennings, J.L.; van der Heide, H.G.; He, Q.; Diavatopoulos, D.; Heuvelman, K.; van Gent, M.; van Leeuwen, K.; Mooi, F.R. Comparative genomic profiling of Dutch clinical Bordetella pertussis isolates using DNA microarrays: Identification of genes absent from epidemic strains. BMC Genomics 2008, 9, 311.
-
(2008)
BMC Genomics
, vol.9
, pp. 311
-
-
King, A.J.1
Van Gorkom, T.2
Pennings, J.L.3
Van Der Heide, H.G.4
He, Q.5
Diavatopoulos, D.6
Heuvelman, K.7
Van Gent, M.8
Van Leeuwen, K.9
Mooi, F.R.10
-
50
-
-
27444442408
-
Are vaccination programs and isolate polymorphism linked to pertussis re-emergence?
-
Godfroid, F.; Denoel, P.; Poolman, J. Are vaccination programs and isolate polymorphism linked to pertussis re-emergence? Expert Rev. Vaccines 2005, 4, 757-778.
-
(2005)
Expert Rev. Vaccines
, vol.4
, pp. 757-778
-
-
Godfroid, F.1
Denoel, P.2
Poolman, J.3
-
51
-
-
79953111292
-
Clostridium baratii Type F Neurotoxin Cleaves Synaptobrevin-2 with Different Substrate Recognition Requirement than Clostridium botulinum Type F Neurotoxin
-
Kalb, S.R.; Baudys, J.; Egan, C.; Smith, T.J.; Smith, L.A.; Pirkle, J.L.; Barr, J.R. Clostridium baratii Type F Neurotoxin Cleaves Synaptobrevin-2 with Different Substrate Recognition Requirement than Clostridium botulinum Type F Neurotoxin. Appl. Environ. Microbiol. 2011, 77, 1301-1308.
-
(2011)
Appl. Environ. Microbiol.
, vol.77
, pp. 1301-1308
-
-
Kalb, S.R.1
Baudys, J.2
Egan, C.3
Smith, T.J.4
Smith, L.A.5
Pirkle, J.L.6
Barr, J.R.7
|