Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study

BMC Neurology

Volumn 11, Issue , 2011, Pages

  Moldofsky, Harvey ^a   Patcai, John ^b,c  

^a Sleep Disorders Clinic of the Centre for Sleep and Chronobiology   (Canada)

^b St John's Rehabilitation Hospital   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CASE CONTROL STUDY; CHRONIC FATIGUE SYNDROME; CONTROLLED STUDY; DEPRESSION; ELECTROENCEPHALOGRAM; FATIGUE; FEMALE; FIBROMYALGIA; HEALTH CARE PERSONNEL; HUMAN; HUMAN EXPERIMENT; MALE; MUSCLE WEAKNESS; MUSCULOSKELETAL PAIN; NORMAL HUMAN; REM SLEEP; REM SLEEP DEPRIVATION; SEVERE ACUTE RESPIRATORY SYNDROME; SLEEP APNEA SYNDROME; SLEEP DISORDER; SLEEP PATTERN; CHRONIC DISEASE; MIDDLE AGED; MUSCLE DISEASE; PAIN; PATHOPHYSIOLOGY;

CASE-CONTROL STUDIES; CHRONIC DISEASE; DEPRESSION; FATIGUE; FATIGUE SYNDROME, CHRONIC; FEMALE; FIBROMYALGIA; HUMANS; MALE; MIDDLE AGED; MUSCULAR DISEASES; PAIN; SEVERE ACUTE RESPIRATORY SYNDROME; SLEEP DISORDERS;

EID: 79953071284     PISSN: None     EISSN: 14712377     Source Type: Journal    
DOI: 10.1186/1471-2377-11-37     Document Type: Article

References (59)

1. Booth CM, Matukas LM, Tomlinson GA, Rachlis AR, Rose DB, Dwosh HY, et al. Clinical Features and Short-term Outcomes of 144 Patients With SARS in the Greater Toronto Area. JAMA 2003, 289:2801-2809. 10.1001/jama.289.21.JOC30885, 12734147.
2. Muller MP, Richardson SE, McGeer A, Dresser L, Raboud J, Mazzulli T, et al. Early diagnosis of SARS: lessons from the Toronto SARS outbreak. Eur J Clin Microbiol Infect Dis 2006, 25:230-237. 10.1007/s10096-006-0127-x, 16586072.
3. McDonald LC, Simor AE, Su IJ, Malone S, Ofner M, Chen KT, et al. SARS in healthcare facilities, Toronto and Taiwan. Emerg Infect Dis [serial on the Internet] 2004, http://www.cdc.gov/ncidod/EID/vol10no5/03-0791.htm
4. Avendano M, Derkach P, Swan S. Clinical course and management of SARS in health care workers in Toronto: a case series. CMAJ 2003, 168(13):1649-1660. 161610, 12821618.
5. Ksiazek TG, Erdman D, Goldsmith CS, Zaki SR, Peret T, Emery S, et al. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med 2003, 348:1953-66. 10.1056/NEJMoa030781, 12690092.
6. Marra MA, Jones SJM, Astell CR, Holt RA, Brooks-Wilson A, Brooks-Wilson A, Butterfield, Yaron SN, et al. The Genome Sequence of the SARS-Associated Coronavirus. Science 2003, 300:1399-1404. 10.1126/science.1085953, 12730501.
7. Hamming I, Timens W, Bulthuis ML, Lely AT, Navis GJ, van Goor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. Journal of Pathology 2004, 203(2):631-7. 10.1002/path.1570, 15141377.
8. Low DE, McGeer A. SARS--one year later. New Engl J Med 2003, 349(25):2381-2. 10.1056/NEJMp038203, 14681502.
9. Wahler HR. The physical symptoms inventory: measuring levels of somatic complaining behavior. J Clin Psychol 1968, 24:207-211. 10.1002/1097-4679(196804)24:2<207::AID-JCLP2270240223>3.0.CO;2-G, 5650548.
10. Beck AT, Ward CH, Mendelson M, Monk M, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961, 4:561-571.
11. Beck AT, Rial WY, Rickels K. Short form of depression inventory: cross-validation. Psychological Reports 1974, 34:1184-6.
12. Blanchard EB, Jones-Alexander J, Buckley TC, Forneris CA. Psychometric properties of the PTSD Checklist (PCL). Behav Res Ther 1996, 34:669-73. 10.1016/0005-7967(96)00033-2, 8870294.
13. Unger ER, Nisenbaum R, Moldofsky H, Cesta A, Sammut C, Reyes M, et al. Sleep assessment in a population-based study of chronic fatigue syndrome. BMC Neurol 2004, 4(1):6. 10.1186/1471-2377-4-6, 419502, 15096280.
14. Rechtshaffen A, Kales A. A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects. UCLA Brain Info Serv/Brain Res Inst, LA 1968,
15. MacLean AW, Lue F, Moldofsky H. The reliability of visual scoring of alpha EEG activity during sleep. Sleep 1995, 18:565-9.
16. van den Hoed J, Kraemer H, Guilleminault C, Zarcone VP, Miles LE, Dement WC, et al. Disorders of excessive daytime somnolence: polygraphic and clinical data for 100 patients. Sleep 1981, 4:23-37.
17. Moldofsky H, Saskin P, Lue FA. Sleep and symptoms in fibrositis syndrome after a febrile illness. J of Rheumatol 1988, 15(2):1701-1704.
18. Hoddes E, Zarcone V, Smythe H, Phillips R, Dement WC. Quantification of sleepiness: a new approach. Psychophysiology 1973, 10:431-6. 10.1111/j.1469-8986.1973.tb00801.x, 4719486.
19. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia: report of the multicenter criteria committee. Arthritis Rheum 33(160-172):1990.
20. Rizzi M, Sarzi-Puttini P, Atzeni F, Capsoni F, Andreoli A, Pecis M, et al. Cyclical Alternating Pattern: A new marker for sleep alteration in patients with fibromyalgia. J Rheumatol 2004, 34:1193-99.
21. Moldofsky H, Inhaber NH, Guinta DR, Alvarez-Horine SB. The Effects of Sodium Oxybate on Sleep Physiology and Sleep/Wake-Related Symptoms in Patients with Fibromyalgia Syndrome: A double-blind, randomized, placebo-controlled study. J Rheumatol 2010, 37:2156-66. Epub 2010 Aug 3., 10.3899/jrheum.091041, 20682669.
22. Rosa AC, Parrino L, Terzano MG. Automatic detection of cyclic alternating pattern (CAP) sequences in sleep: preliminary results. Clin Neurophysiol 1999, 110:585-92. 10.1016/S1388-2457(98)00030-3, 10378726.
23. Rosa A, Alves GR, Brito M, Lopes MC, Tufik S. Visual and automatic cyclic alternating pattern (CAP) scoring: inter-rater reliability study. Arq Neuropsiquiatr 2006, 64:578-81.
24. Weathers F, Ford J. Psychometric properties of the PTSD Checklist (PCL-C, PCL-S, PCL-M, PCL-PR). Measurement of Stress, Trauma, and Adaptation 1996, Lutherville, Md: Sidran Press, Stamm BH.
25. Parrino L, Boselli M, Spaggiari MC, Smerieri A, Terzano MG. Cyclic alternating pattern (CAP) in normal sleep: polysomnographic parameters in different age groups. Electroencephalography & Clinical Neurophysiology 1998, 107:439-50.
26. Herridge MS, Cheung AM, Tansey CM, Matte-Martyn A, Diaz-Granados N, Al-Saidi F, et al. One-Year Outcomes In Survivors Of The Acute Respiratory Distress Syndrome. N Engl J Med 2003, 348:683-93. 10.1056/NEJMoa022450, 12594312.
27. May KP, West SG, Baker MR, et al. Sleep apnea in male patients with fibromyalgia syndrome. Am J Med 1993, 94:505-508. 10.1016/0002-9343(93)90085-4, 8498395.
28. Sergi M, Rizzi M, Braghiroli A, et al. Periodic breathing during sleep in patients affected by fibromyalgia syndrome. Eur Respir J 1999, 14:203-208. 10.1034/j.1399-3003.1999.14a34.x, 10489852.
29. Gold AR, Dipalo F, Gold MS, Broderick J. Inspiratory airflow dynamics during sleep in women with fibromyalgia. Sleep 2004, 27:459-466.
30. Grote L, Ploch T, Heitmann J, Knaack L, Penzel T, Peter JH. Sleep-related breathing disorder is an independent risk factor for systemic hypertension. Am J Respir Crit Care Med 1999, 160:1875-1882.
31. Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A, et al. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Int Med 1994, 121:953-959.
32. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia: report of the multicenter criteria committee. Arthritis Rheum 1990, 33:160-172. 10.1002/art.1780330203, 2306288.
33. Branco J, Atalaia A, Paiva T. Sleep cycles and alpha-delta sleep in fibromyalgia syndrome. Journal of Rheumatololog 1994, 21:1113-1117.
34. Drewes AM, Nielsen KD, Taagholt SJ, Bjerregård K, Svendsen L, Gade J. Sleep intensity in fibromyalgia: focus on the microstructure of the sleep process. Br J Rheumatol 1995, 34:629-635. 10.1093/rheumatology/34.7.629, 7670781.
35. Roizenblatt S, Moldofsky H, Benedito-Silva AA, Tufik S. Alpha sleep characteristics in fibromyalgia. Arthritis & Rheumatism 2001, 44:222-30.
36. Whelton CL, Salit I, Moldofsky Sleep H. Epstein-Barr virus infection, musculoskeletal pain, and depressive symptoms in chronic fatigue syndrome. Journal of Rheumatology 1992, 19:939-943.
37. Chen R, Chou K, Huang Y, Wang T, Liu S, Ho L. Effects Of A SARS Prevention Programme In Taiwan On Nursing Staff's Anxiety, Depression And Sleep Quality: A Longitudinal Survey. International Journal of Nursing Studies 2006, 43(2):215-225. 10.1016/j.ijnurstu.2005.03.006, 15927185.
38. Moldofsky H, Scarisbrick P. Induction of neurasthenic musculoskeletal pain syndrome by selective sleep stage deprivation. Psychosom Med 1976, 38:35-44.
39. Glass WG, Subbarao K, Murphy B. Murphy PM. Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice. Journal of Immunology 2004, 173:4030-9.
40. He L, Ding YQ, Che XY, Zhang QL, Huang ZX, Wang HJ, et al. Expression of the monoclonal antibody against nucleocapsid antigen of SARS-associated coronavirus in autopsy tissues from SARS patients. Di Yi Junyi Daxue Xuebao 2003, 23:1128-30.
41. Gu J, Gong E, Zhang B, Zheng J, Gao Z, Zhong Y, et al. Multiple organ infection and the pathogenesis of SARS. J Exp Med 2005, 202:415-424. 10.1084/jem.20050828, 2213088, 16043521.
42. Xu J, Zhong S, Liu J, Li L, Li Y, Wu X, et al. Detection of severe acute respiratory syndrome coronavirus in the brain:potential role of chemikine mig in pathogenesis. Clin Infect Dis 2005, 41:1089-1096. 10.1086/444461, 16163626.
43. Yong G, Kortweg C, McNutt MA, Gu J. Pathogenetic mechanisms of severe acute respiratory syndrome. Virus Research 2008, 133:4-12. 10.1016/j.virusres.2007.01.022, 17825937.
44. Netland J, Meyerholz DK, Moore S, Cassell M, Perlman S. Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2. J Virol 2008, 82:7264-75. 10.1128/JVI.00737-08, 2493326, 18495771.
45. Hickie I, Davenport T, Wakefield D, Vollmer-Conna U, Cameron B, Vernon SD, et al. Dubbo Infection Outcomes Study Group. Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study. BMJ 2006, 333(7568):575. 10.1136/bmj.38933.585764.AE, 1569956, 16950834.
46. Cope H, David A, Pelosi A, Mann A. Predictors of chronic "postviral" fatigue. The Lancet 1994, 344:8926.
47. Lombardi V, Ruscetti FW, Gupta JD, Pfost MA, Hagen KS, Peterson DL, et al. Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome. Science 2009, 326:585-589. 10.1126/science.1179052, 19815723.
48. van der Meer JWM, Netea MG, Galama JMD, van Kuppeveld FM. Comment on "Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome". Science 2010, 328. 825.
49. Hue S, Gray ER, Gall A, Katzourakis A, Tan CP, Houldcroft CJ, et al. Disease-associated XMRV sequences are consistent with laboratory contamination. Retrovirology 2010,
50. Chua SE, Cheung V, Cheung C, McAlonan GM, Wong JW, Cheung EP, et al. Stress and Psychological Impact On SARS Patients During The Outbreak. Can J Psychiatry 2004, 49:201-206.
51. Hui DS, Joynt GM, Wong KT, Gomersall CD, Li TS, Antonio G, et al. Impact of Severe Acute Respiratory Syndrome (SARS) On Pulmonary Function, Functional Capacity And Quality Of Life In A Cohort Of Survivors. Thorax 2005, 60:401-409. 10.1136/thx.2004.030205, 1758905, 15860716.
52. Chan JWM, Ng CK. Severe Acute Respiratory Syndrome (SARS): A Brief Review With Exploration of the Outcomes, Prognostic Factors and Sequelae. Current Respiratory Medicine Reviews 2005, 1:85-92.
53. Chan PK, Tang JW, Hui DS. SARS: clinical presentation, transmission, pathogenesis and treatment options. Clinical Science 2006, 110:193-204. 10.1042/CS20050188, 16411895.
54. Maunder R, Hunter J, Vincent L, Bennett J, Peladeau N, Leszcz M, et al. The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital. CMAJ 2003, 168:1245-51. 154178, 12743065.
55. Robertson E, Hershenfield K, Grace SL, Stewart DE. The psychosocial effects of being quarantined following exposure to SARS: a qualitative study of Toronto health care workers. Can J Psychiatry 2004, 49:403-407.
56. Maunder RG, Lancee WJ, Balderson KE, Bennett JP, Borgundvaag B, Evans S, et al. Long-term Psychological and Occupational Effects of Providing Hospital Healthcare during SARS Outbreak. Emerg Infect Dis 2006, 12:1924-32.
57. Lau HM, Lee EW, Wong C, Ng G, Jones A, Hui D. The Impact of Severe Acute Respiratory Syndrome on the Physical Profile and Quality of Life. Archives of Physical Medicine and Rehabilitation 2005, 86:1134-1140. 10.1016/j.apmr.2004.09.025, 15954051.
58. Chua SE, Cheung V, Cheung C, McAlonan GM, Wong JW, Cheung EP, et al. Psychological effects of the SARS outbreak in Hong Kong on high-risk health care workers. Can J Psychiatry 2004, 49:391-3.
59. Mak IW, Chu CM, Pan PC, Yiu MG, Chan VL. Long-term psychiatric morbidities among SARS survivors. Gen Hosp Psychiatry 2009, 31:318-26. 10.1016/j.genhosppsych.2009.03.001, 19555791.