Diverse effects of FK506 on the apoptosis of hepatocytes and infiltrating lymphocytes in an allografted rat liver

Journal of Surgical Research

Volumn 167, Issue 1, 2011, Pages 131-139

  Moriuchi, Hiroki ^a,b   Kamohara, Yukio ^a   Eguchi, Susumu ^a   Gu, Weili ^a   Fujioka, Hikaru ^a   Yamamoto, Takao ^a   Tajima, Yoshitsugu ^a   Kanematsu, Takashi ^a   Koji, Takehiko ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b National Saga Hospital   (Japan)

Author keywords

apoptosis; Bax; Bcl 2; Fas; Fas ligand; FK506; liver transplantation

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; FAS LIGAND; PROTEIN BAX; PROTEIN BCL 2; TACROLIMUS;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; LIVER CELL; LIVER GRAFT; LIVER GRAFT REJECTION; LYMPHOCYTIC INFILTRATION; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; BCL-2-ASSOCIATED X PROTEIN; BILIRUBIN; FAS LIGAND PROTEIN; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HEPATOCYTES; IMMUNOSUPPRESSIVE AGENTS; LIVER; LIVER TRANSPLANTATION; LYMPHOCYTES; MALE; MODELS, ANIMAL; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, INBRED LEW; RATS, INBRED STRAINS; TACROLIMUS; TRANSPLANTATION, HOMOLOGOUS;

EID: 79953061639     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2009.06.054     Document Type: Article

References (52)

1. S. Seki, T. Kitada, and S. Iwai Immunohistochemical detection of Fas and apoptosis in type-1 autoimmune hepatitis Hepatogastroenterology 50 2003 1274
2. M. Bortolami, A. Kotsafti, and R. Cardin Fas/FasL system, IL-1beta expression and apoptosis in chronic HBV and HCV liver disease J Viral Hepat 15 2008 515
3. K. Soe, Y. Hishikawa, and Y. Fukuzawa Possible correlation between iron deposition and enhanced proliferating activity in hepatitis C virus-positive hepatocellular carcinoma in Myanmar (Burma) J Gastroenterol 42 2007 225
4. P.C. Kuo, C.I. Drachenberg, and A. de la Torre Apoptosis and hepatic allograft reperfusion injury Clin Transplantation 12 1998 219
5. K. Okada, K. Komuta, and S. Hashimoto Frequency of apoptosis of tumor-infiltrating lymphocytes induced by Fas counterattack in human colorectal carcinoma and its correlation with prognosis Clin Cancer Res 6 2000 3560
6. C. Battersby, and W.S. Egerton Another look at rejection in pig liver allografts Surgery 76 1974 617
7. B. Desske, X. Lin, and D.S. Huang Spontaneous tolerance: Experience with the rat liver transplant model Hum Immunol 63 2002 853
8. A. Sharland, S. Shastry, and C. Wang Kinetics of intragraft cytokine expression, cellular infiltration, and cell death in rejection of renal allografts compared with acceptance of liver allografts in a rat model Transplantation 65 1998 1370
9. M.J. Tocci, D.A. Mattkovich, and K.A. Collier The immunosuppressant FK506 selectively inhibits expression of early T-cell activation genes J Immunol 143 1989 718
10. S.L. Schreiber, and G.R. Crabtree The mechanism of action of cyclosporin A and FK506 Immunol Today 13 1992 136
11. K. Migita, T. Origuchi, and Y. Kawabe FK506 markedly enhances apoptosis of antigen-stimulated peripheral T cells by down-regulation of Bcl-xL Transplantation 68 1999 1018
12. N. Kamada, and R.Y. Calne A surgical experience with 530 liver transplants in the rat Surgery 93 1983 64
13. N. Hakuno, T. Koji, and T. Yano Fas/APO-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia Endocrinology 137 1996 1938
14. J.C. Adams Heavy metal intensification of DAB-based HRP reaction product J Histchem Cytochem 29 1981 775
15. S. Krajewski, M. Krajewska, and A. Shabaik Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2 Am J Pathol 145 1994 1323
16. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 1976 248
17. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680
18. T. Koji, N. Kobayashi, and Y. Nakanishi Immunohistochemical localization of Fas antigen paraffin sections with rabbit antibodies against human synthetic Fas peptides Acta Histochem Cytochem 27 1994 459
19. H. Ehara, T. Deguchi, and T. Koji Autoclave antigen retrieval technique for immunohistochemical staining of androgen receptor in formalin-fixed paraffin sections of human prostate Acta Histochem Cytochem 29 1996 4311
20. X.K. Li, T. Okuyama, and A. Tamura Prolonged survival of rat liver allografts transfected with Fas ligand-expressing plasmid Transplantation 66 1998 1416
21. A.J. Demetris, K.P. Batts, and A.P. Dhillon Banff schema for grading liver allograft rejection: An international consensus document Hepatology 25 1996 658
22. J.C. Reed, T. Miyashita, and S. Takayama BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapy J Cell Biochem 60 1996 23
23. H. Kurosawa, F.G. Que, and L.R. Roberts Hepatocytes in the bile duct-ligated rat express Bcl-2 Am J Physiol 272 1997 G1587
24. A. Horigome, T. Hirano, and K. Oka Tacrolimus-induced apoptosis and its prevention by interleukins in mitogen-activated human peripheral-blood mononuclear cells Immunopharmacology 39 1998 21
25. S. Suzuki, L.H. Toledo-Pereyra, and F.J. Rodriguez Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine Transplantation 55 1993 1265
26. F.J. Garcia-Criado, J.M. Palma-Vargas, and J.J. Valdunciel-Garcia Tacrolimus (FK506) down-regulates free radical tissue levels, serum cytokines, and neutrophil infiltration after severe liver ischemia Transplantation 27 1997 594
27. T. Matsuda, Y. Yamaguchi, and F. Matsumura Immunosuppressants decrease neutrophil chemoattractant and attenuate ischemia/reperfusion injury of the liver in rats J Trauma 44 1998 475
28. D. Crenesse, M. Laurens, and C. Heurteaux Rat liver ischemia-reperfusion- induced apoptosis and necrosis are decreased by FK506 pretreatment Eur J Pharmacol 473 2003 177
29. M. Laurens, G. Scozzari, and D. Patrono Warm ischemia-reperfusion injury is decreased by tacrolimus in steatotic rat liver Liver Transpl 12 2006 217
30. S. Nagata, and P. Golstein The Fas death factor Science 267 1995 1449
31. N. Itoh, S. Yonehara, and A. Ishii The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis Cell 66 1991 233
32. I. Yokoyama, A. Hayakawa, and S. Hayashi Fas antigen expression of hepatocytes and its modification by immunosuppressants Dig Dis Sci 42 1997 2471
33. T. Shinagawa, K. Yoshioka, and S. Kakumu Apoptosis in cultured rat hepatocytes: The effects of tumor necrosis factor alpha and interferon gamma J Pathol 165 1991 247
34. C.S. Guy, J. Wang, and T.I. Michalak Hepatocytes as cytotoxic effector cells can induce cell death by CD95 ligand-mediated pathway Hepatology 43 2006 1231
35. L. Aoudjehane, P. Podevin, and O. Scatton Interleukin-4 induces human hepatocyte apoptosis through a Fas-independent pathway FASEB J 21 2007 1433
36. M.J. Gómez-Lechón, A. Serralta, and M.T. Donato The immunosuppressant drug FK506 prevents Fas-induced apoptosis in human hepatocytes Biochem Pharmacol 15 2004 68 2427
37. R.M. Kluck, E. Bossy-Wetzel, and D.R. Green The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis Science 275 1997 1132
38. J.S. Kim, T. Qian, and J.J. Lemasters Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes Gastroenterology 124 2003 494
39. S. Shimizu, M. Narita, and Y. Tsujimoto Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC Nature 399 1999 483
40. K. Ikeda, H. Kinoshita, and K. Hirohashi The ultrastructure, kinetics, and intralobular distribution of apoptotic hepatocytes after portal branch ligation with special reference to their relationship to necrotic hepatocytes Arch Histol Cytol 58 1995 171
41. G. Borghi-Scoazec, J.Y. Scoazec, and F. Durand Apoptosis after ischemia-reperfusion in human liver allografts Liver Transpl Surg 3 1997 407
42. K. Ohno, P. Ammann, and R. Fasciati Transforming growth factor beta 1 preferentially induces apoptotic cell death in rat hepatocytes cultured under pericentral-equivalent conditions Toxicol Appl Pharmacol 132 1995 227
43. T. Oshiro, M. Shiraishi, and Y. Muto Adenovirus mediated gene transfer of antiapoptotic protein in hepatic ischemia-reperfusion injury: The paradoxical effect of Bcl-2 expression in the reperfused liver J Surg Res 103 2002 30
44. M. Rentsch, K. Kienle, and T. Mueller Adenoviral bcl-2 transfer improves survival and early graft function after ischemia and reperfusion in rat liver transplantation Transplantation 80 2005 1461
45. G. Zajicek, R. Oren, and M. Weinreb Jr. The streaming liver Liver 5 1985 293
46. X. Li, J.F. Zhang, and M.Q. Lu Alleviation of ischemia-reperfusion injury in rat liver transplantation by induction of small interference RNA targeting Fas Langenbecks Arch Surg 392 2007 345
47. D.S. Wang, Y. Li, and K.F. Dou Utility of adenovirus-mediated Fas ligand and bcl-2 gene transfer to modulate rat liver allograft survival Hepatobiliary Pancreat Dis Int 5 2006 505
48. M. Rivero, J. Crespo, and M. Mayorga Involvement of the Fas system in liver allograft rejection Am J Gastroenterol 97 2002 1501
49. M. Selzner, H.A. Rüdiger, and N. Selzner Transgenic mice overexpressing human Bcl-2 are resistant to hepatic ischemia and reperfusion J Hepatol 36 2002 218
50. Z. Ben-Ari, O. Pappo, and Y. Cheporko Bax ablation protects against hepatic ischemia/reperfusion injury in transgenic mice Liver Transpl 13 2007 1181
51. H. Nakajima, N. Mizuta, and I. Fujiwara Blockade of the Fas/Fas ligand interaction suppresses hepatocyte apoptosis in ischemia-reperfusion rat liver Apoptosis 13 2008 1013
52. S.M. Krams, C.K. Fox, and P.R. Beatty Human hepatocytes produce an isoform of Fas that inhibits apoptosis Transplantation 65 1998 713