Antagonist interaction with the human 5-HT 7 receptor mediates the rapid and potent inhibition of non-G-protein-stimulated adenylate cyclase activity: A novel GPCR effect

British Journal of Pharmacology

Volumn 162, Issue 8, 2011, Pages 1843-1854

  Klein, M T ^a   Teitler, M ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

5 HT; drug receptor mechanisms; GPCRs; Neuropharmacology

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; ADENYLATE CYCLASE; AMOXAPINE; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; BROMOCRIPTINE; CLOZAPINE; CYCLIC AMP; CYPROHEPTADINE; FLUPHENAZINE; FORSKOLIN; KETANSERIN; LISURIDE; MESULERGINE; METERGOLINE; METHYSERGIDE; METITEPINE; PALIPERIDONE; RISPERIDONE; SEROTONIN 6 RECEPTOR; SEROTONIN 7 RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL STRAIN HEK293; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; DRUG RECEPTOR BINDING; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENYLATE CYCLASE; CLOZAPINE; CYCLIC AMP; FORSKOLIN; HEK293 CELLS; HUMANS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS;

EID: 79953045023     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01194.x     Document Type: Article

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