HIF-1α and VEGF are associated with disease progression in esophageal carcinoma

Journal of Surgical Research

Volumn 167, Issue 1, 2011, Pages 41-48

  Takala, Heikki ^a   Saarnio, Juha ^a   Wiik, Heikki ^a   Ohtonen, Pasi ^a   Soini, Ylermi ^b  

^a OULU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

eNOS; esophageal carcinoma; HIF 1 ; iNOS; nNOS; VEGF

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; VASCULOTROPIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CANCER GROWTH; CANCER INVASION; CANCER STAGING; CONTROLLED STUDY; DISEASE COURSE; DISTANT METASTASIS; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; ESOPHAGUS CARCINOMA; ESOPHAGUS SURGERY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENOCARCINOMA; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CELL PROLIFERATION; DISEASE PROGRESSION; ESOPHAGEAL NEOPLASMS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NEOVASCULARIZATION, PATHOLOGIC; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; RETROSPECTIVE STUDIES; TUMOR MARKERS, BIOLOGICAL; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79953042650     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2009.11.725     Document Type: Article

References (50)

1. S. Law, D.L. Kwong, and K.F. Kwok Improvement in treatment results and long-term survival of patients with esophageal cancer: Impact of chemoradiation and change in treatment strategy Ann Surg 238 2003 339
2. M.C. Posner, W.E. Gooding, and R.J. Landreneau Preoperative chemoradiotherapy for carcinoma of the esophagus and gastroesophageal junction Cancer J Sci Am 4 1998 237
3. E. Laterza, G. de Manzoni, and P. Tedesco Induction chemo-radiotherapy for squamous cell carcinoma of the thoracic esophagus: Long-term results of a phase II study Ann Surg Oncol 6 1999 777
4. J.F. Bosset, M. Gignoux, and J.B. Triboulet Chemoradiotherapy followed by surgery compared with surgery alone in squamous-cell cancer of the esophagus N Engl J Med 337 1997 161
5. B.H. Burmeister, B.M. Smithers, and V. Gebski Trans-Tasman Radiation Oncology Group; Australasian gastro-Intestinal Trials Group. Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: A randomized controlled phase III trial Lancet Oncol 6 2005 659
6. H. Kimura, and H. Esumi Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis Acta Biochim Pol 50 2003 49
7. J. Folkman What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82 1990 4
8. G.U. Dachs, and G.M. Tozer Hypoxia modulated gene expression, angiogenesis, metastasis and therapeutic exploitation Eur J Cancer 36 2000 1649
9. L.E. Huang, J. Gu, M. Schau, and H.F. Bunn Regulation of hypoxia-inducible factor 1α is mediated by an O2-dependent degradation domain via the ubiquitin-proteosome pathway Proc Natl Acad Sci USA 95 1998 7987
10. P. Birner, M. Schindl, and A. Obermai Overexpression of hypoxia-inducible factor 1 is a marker for an unfavorable prognosis in early-stage invasive cervical cancer Cancer Res 60 2000 4693
11. H. Zhong, A.M. De Marzo, and E. Laughner Overexpression of hypoxia-inducible factor 1 in common human cancers and their metastases Cancer Res 59 1999 5830
12. T. Matsuyama, K. Nakanishi, and T. Hayashi Expression of hypoxia-inducible factor-1α in esophageal squamous cell carcinoma Cancer Sci 96 2005 176
13. M. Sohda, H. Ishikawa, and N. Masuda Pretreatment evaluation of combined HIF-1α, P53, and P21 expression is a useful and sensitive indicator of response to radiation and chemotherapy in esophageal cancer Int J cancer 110 2004 838
14. M. Ema, S. Taya, and N. Yokotani A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1 regulates the VEGF expression and is potentially involved in lung and vascular development Proc Natl Acad Sci USA 94 1997 4273
15. A. Kleespies, M. Guba, and K.W. Jauch Vascular endothelial growth factor in esophageal cancer J Surg Oncol 87 2004 95
16. R.T. Poon, S.T. Fan, and J. Wong Clinical significance of angiogenesis in gastrointestinal cancers: A target for novel prognostic and therapeutic approaches Ann Surg 238 2003 9
17. N. Ferrara, and W.J. Henzel Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells Biochem Biophys Res Commun 161 1989 851
18. E.N. Unemori, N. Ferrara, and E.A. Bauer Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells J Cell Physiol 153 1992 557
19. A. Pettersson, J.A. Nagy, and L.F. Brown Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor Lab Invest 80 2000 99
20. J.E. Nör, J. Christensen, and D.J. Mooney Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression Am J Pathol 154 1999 375
21. T. Kuwai, Y. Kitadai, and S. Tanaka Expression of hypoxia inducible factor-1a is associated with tumor vascularization in human colorectal carcinoma Int J Cancer 105 2003 176
22. M.I. Koukourakis, A. Giatromanolaki, and E. Sivridis Hypoxia inducible factor (HIF1a and HIF2a), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer Int J Radiat Oncol Biol Phys 53 2002 1192
23. S. Kimura, Y. Kitadai, and S. Tanaka Expression of hypoxia-inducible factor (HIF)-1α is associated with vascular endothelial growth factor expression and tumour angiogenesis in human esophageal carcinoma Eur J Cancer 40 2004 1904
24. P.A. Brennan, I.P. Downie, and J.D. Langdon Emerging role of nitric oxide in cancer Br J Oral Maxillofac Surg 37 1999 370
25. W. Xu, L.Z. Liu, and M. Loizidou The role of nitric oxide in cancer Cell Res 12 2002 311
26. M. Quintero, Brennan Pa, and G.J. Thomas Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1α in cancer: Role of free radical formation Cancer Res 66 2006 770
27. L.E. Huang, W.G. Willmore, and J. Gu Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling J Biol Chem 274 1999 9038
28. K.T. Wilson, S. Fu, K.S. Ramanujam, and S.J. Metzer Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in Barrett's esophagus and associated adenocarcinomas Cancer Res 58 1998 2929
29. H. Tanaka, H. Kijima, and T. Tokunaga Frequent expression of inducible nitric oxide synthase in esophageal squamous cell carcinomas Int J Oncol 14 1999 1069
30. M. Matsumoto, M. Furihata, and A. Kurabayashi Association between inducible nitric oxide synthase expression and p53 status in human esophageal squamous cell carcinoma Oncology 64 2003 90
31. Z.J. Shang, and J.R. Li Expression of endothelial nitric oxide synthase and vascular endothelial growth factor in oral squamous cell carcinoma: Its correlation with angiogenesis and disease progression J Oral Pathol Med 34 2005 134
32. S.R. Hamilton, and L.A. Aaltonen Tumours of the digestive system. Pathology and genetics. World Health Organization classification of tumours 2000 IARC Press Lyon 10-25
33. F. Bussolino, A. Mantovani, and G. Persico Molecular mechanisms of blood vessel formation Trends Biochem Sci 22 1997 251
34. C. Brahimi-Horn, and J. Poysségur The role of the hypoxia-inducible factor in tumor metabolism growth and invasion Bull Cancer 93 2006 E73
35. T. Kurokawa, M. Miyamoto, and K. Kato Overexpression of hypoxia-inducible-factor 1a(HIF-1a) in oesophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage Br J Cancer 89 2003 1042
36. Y. Kitadai, K. Haruma, and T. Tokutomi Significance of vessel count and vascular endothelial growth factor in human esophageal carcinomas Clin Cancer Res 4 1998 2195
37. K. Inoue, Y. Ozeki, and T. Suganuma Vascular endothelial growth factor expression in primary esophageal squamous cell carcinoma. Association with angiogenesis and tumor progression Cancer 79 1997 206
38. M. Krzystek-Korpacka, M. Matusiewicz, and D. Diakowska Upregulation of VEGF-C secreted by cancer cells and not VEGF-A correlates with clinical evaluation of lymph node metastasis in esophageal squamous cell carcinoma (ESCC) Cancer Lett 249 2007 171
39. R. Du, Y. Jiang, and Y.M. Zhang Vascular endothelial growth factor and microvascular density in esophageal and gastric carcinomas World J Gastroenterol 9 2003 1604
40. P.A. Brennan, and M. Quintero Regulation of hypoxia-inducible factor 1 (HIF-1) by nitric oxide in oral squamous cell carcinoma Ann R Coll Surg Engl 87 2005 153
41. J.-X. Yu, L. Cui, and Q.-Y. Zhang Expression of NOS and HIF-1α in human colorectal carcinoma and implication in tumor angiogenesis World J Gastroenterol 12 2006 4660
42. J.W. Pan, R.Y. Zhan, and Y. Tong Expression of endothelial nitric oxide synthase and vascular endothelial growth factor in association with neovascularization in human primary astrocytoma J Zhejiang Univ Sci B 6 2005 693
43. R. Chandra, G.K. Haines III, and B.G. Bentz Expression of nitric oxide synthase type 3 in reflux-induced esophageal lesions Otolaryngol Head Neck Surg 124 2001 442
44. Z.Y. Song, S.Q. Wen, and J.P. Peng Significance of vascular endothelial growth factor expression and its correlation with inducible nitric oxide synthase in gastric cancer World J Gastroenterol 10 2004 1250
45. C.H. Lee, M.K. Lee, and C.D. Kang Differential expression of hypoxia inducible factor-1α and tumor cell proliferation between squamous cell carcinomas and adenocarcinomas among operable non-small cell lung carcinomas J Korean Med Sci 18 2003 196
46. J.A. Forsythe, B.H. Jiang, and N.V. Iyer Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 Mol Cell Biol 16 1996 4604
47. L.A. Palmer, G.L. Semenza, and M.H. Stoler Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1 Am J Physiol 274 1998 212
48. F. Coulet, S. Nadaud, and M. Agrapart Identification of hypoxia-response element in the human endothelial nitric-oxide synthase gene promoter J Biol Chem 278 2003 46230
49. C.A. Gruetter, B.K. Barry, and D.B. McNamara Relaxation of bovine coronary artery and activation of coronary arterial guanylate cyclase by nitric oxide nitroprusside and a carcinogenic nitrosamine J Cyclic Nucleotide 5 1979 211
50. R.F. Furchgott, and J.V. Zawadzki The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine Nature 288 1980 373