Helix 8 of the M1 muscarinic acetylcholine receptor: scanning mutagenesis delineates a G protein recognition site

Molecular Pharmacology

Volumn 79, Issue 4, 2011, Pages 701-709

  Kaye, Robert G ^a,c   Saldanha, José W ^a   Lu, Zhi Liang ^b   Hulme, Edward C ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b XI AN JIAOTONG LIVERPOOL UNIVERSITY   (China)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMIDE; AMINO ACID; ASPARAGINE; CYSTEINE; GUANINE NUCLEOTIDE BINDING PROTEIN; LEUCINE; MUSCARINIC M1 RECEPTOR; PHENYLALANINE;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; HELIX 8; HUMAN; MOLECULAR MODEL; MOLECULAR RECOGNITION; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; TRANSMEMBRANE HELIX 7; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; GENETICS; METABOLISM; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; RAT;

ALANINE; ANIMALS; BINDING SITES; CERCOPITHECUS AETHIOPS; COS CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEINS; MUTAGENESIS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTOR, MUSCARINIC M1;

EID: 79953016938     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.070177     Document Type: Article

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