Acetaminophen-induced hepatotoxicity in mice occurs with inhibition of activity and nitration of mitochondrial manganese superoxide dismutase

Journal of Pharmacology and Experimental Therapeutics

Volumn 337, Issue 1, 2011, Pages 110-116

  Agarwal, Rakhee ^a   MacMillan Crow, Lee Ann ^a   Rafferty, Tonya M ^a   Saba, Hamida ^a   Roberts, Dean W ^a   Fifer, E Kim ^b   James, Laura P ^a   Hinson, Jack A ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; GLUTATHIONE; MANGANESE SUPEROXIDE DISMUTASE; PARACETAMOL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; LIVER HOMOGENATE; LIVER TOXICITY; MALE; MOUSE; NITRATION; NONHUMAN; PRIORITY JOURNAL;

ACETAMINOPHEN; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; ENZYME INHIBITORS; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA, LIVER; NITRATES; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE;

EID: 79953016028     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.176321     Document Type: Article

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