Pigment epithelium-derived factor receptor (PEDF-R): A plasma membrane-linked phospholipase with PEDF binding affinity

Advances in Experimental Medicine and Biology

Volumn 664, Issue , 2010, Pages 29-37

  Subramanian, Preeti ^b   Notario, Patricia M ^b   Becerra, S Patricia ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PHOSPHOLIPASE; PHOSPHOLIPASE A2; PIGMENT EPITHELIUM DERIVED FACTOR; PIGMENT EPITHELIUM DERIVED FACTOR RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTERIOR EYE SEGMENT; BINDING AFFINITY; CELL FRACTIONATION; CHOROID; CONFERENCE PAPER; ENZYME ACTIVITY; HUMAN; LACRIMAL GLAND; LENS; LIGAND BINDING; MEMBRANE STRUCTURE; NONHUMAN; OPTIC NERVE; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RETINA; RETINA CELL; SIGNAL TRANSDUCTION;

CELL MEMBRANE; COMPUTATIONAL BIOLOGY; EYE PROTEINS; HUMANS; LIGANDS; NERVE GROWTH FACTORS; PHOSPHOLIPASES; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, NEUROPEPTIDE; RETINA; SERPINS; SUBCELLULAR FRACTIONS;

EID: 79952929168     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-1399-9_4     Document Type: Conference Paper

References (31)

1. Alberdi E, AymerichMS, Becerra SP (1999) Binding of pigment epithelium-derived factor (PEDF) to retinoblastoma cells and cerebellar granule neurons. Evidence for a PEDF receptor. J Biol Chem 274:31605-31612
2. Aymerich MS, Alberdi EM, Martinez A et al (2001) Evidence for pigment epithelium-derived factor receptors in the neural retina. Invest Ophthalmol Vis Sci 42:3287-3293 (Pubitemid 33740692)
3. Barnstable CJ, Tombran-Tink J (2004) Neuroprotective and antiangiogenic actions of PEDF in the eye: Molecular targets and therapeutic potential. Prog Retin Eye Res 23:561-577 (Pubitemid 39078362)
4. Bazan NG (2005) Neuroprotectin D1 (NPD1): A DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress. Brain Pathol 15:159-166 (Pubitemid 40546172)
5. Bazan NG, Marcheselli VL, Hu J et al (2005) Pigment epithelium-derived growth factor (PEDF) selectively up-regulates NPD1 synthesis and release through the apical side of human RPE cells in primary cultures. Invest Ophthalmol Vis Sci 46:167
6. Becerra SP (2006) Focus on Molecules: Pigment epithelium-derived factor (PEDF). Exp Eye Res 82:739-740
7. Becerra SP, Fariss RN,Wu YQ et al (2004) Pigment epithelium-derived factor in themonkey retinal pigment epithelium and interphotoreceptor matrix: Apical secretion and distribution. Exp Eye Res 78:223-234 (Pubitemid 38077229)
8. Bilak MM, Corse AM, Bilak SR et al (1999) Pigment epithelium-derived factor (PEDF) protects motor neurons from chronic glutamate-mediated neurodegeneration. J Neuropathol Exp Neurol 58:719-728 (Pubitemid 29328501)
9. Bouck N (2002) PEDF: Anti-angiogenic guardian of ocular function. Trends Mol Med 8:330-334 (Pubitemid 34733386)
10. Cao W, Tombran-Tink J, Elias R et al (2001) In vivo protection of photoreceptors from light damage by pigment epithelium-derived factor. Invest Ophthalmol Vis Sci 42:1646-1652 (Pubitemid 32520760)
11. Cayouette M, Smith SB, Becerra SP et al (1999) Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations. Neurobiol Dis 6:523-532 (Pubitemid 30036622)
12. Chader GJ (2005) Surmountable challenges in translating pigment epithelium-derived factor (PEDF) therapy from animal models to clinical trials for retinal degenerations. Retina (Philadelphia, PA) 25:S29-S30 (Pubitemid 44726512)
13. Dawson DW, Volpert OV, Gillis P et al (1999) Pigment epithelium-derived factor: A potent inhibitor of angiogenesis. Science 285:245-248 (Pubitemid 29329995)
14. Duh EJ, Yang HS, Haller JA et al (2004) Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: Implications for ocular angiogenesis. Am J Ophthalmol 137:668-674 (Pubitemid 38446681)
15. Duh EJ, Yang HS, Suzuma I et al (2002) Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. Invest Ophthalmol Vis Sci 43:821-829 (Pubitemid 34184503)
16. Hirschberg HJ, Simons JW, Dekker N et al (2001) Cloning, expression, purification and characterization of patatin, a novel phospholipase A. Eur J Biochem 268:5037-5044 (Pubitemid 32955555)
17. Holekamp NM, Bouck N, Volpert O (2002) Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration. Am J Ophthalmol 134:220-227 (Pubitemid 34831826)
18. Hubbard T, Andrews D, CaccamoMet al (2005) Ensembl 2005. Nucleic Acids Res 33:D447-D453 (Pubitemid 40207913)
19. Jenkins CM, Mancuso DJ, Yan W et al (2004) Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. J Biol Chem 279:48968-48975 (Pubitemid 39625778)
20. Jimenez-Atienzar M, Cabanes J, Gandia-Herrero F et al (2003) Determination of the phospholipase activity of patatin by a continuous spectrophotometric assay. Lipids 38:677-682 (Pubitemid 36944703)
21. Murakami Y, Ikeda Y, Yonemitsu Y et al (2008) Inhibition of nuclear translocation of apoptosisinducing factor is an essentialmechanism of the neuroprotective activity of pigment epitheliumderived factor in a rat model of retinal degeneration. Am J Pathol 173:1326-1338
22. Notari L, Baladron V, Aroca-Aguilar JD et al (2006) Identification of a lipase-linked cell membrane receptor for pigment epithelium-derived factor. J Biol Chem 281:38022-38037 (Pubitemid 46042106)
23. Ogata N, Matsuoka M, Imaizumi M et al (2004) Decreased levels of pigment epitheliumderived factor in eyes with neuroretinal dystrophic diseases. Am J Ophthalmol 137: 1129-1130 (Pubitemid 38759368)
24. Perez-Mediavilla LA, Chew C, Campochiaro PA et al (1998) Sequence and expression analysis of bovine pigment epithelium-derived factor. Biochim Biophys Acta 1398:203-214 (Pubitemid 28305213)
25. Rydel TJ, Williams JM, Krieger E et al (2003) The crystal structure, mutagenesis, and activity studies reveal that patatin is a lipid acyl hydrolase with a Ser-Asp catalytic dyad. Biochemistry 42:6696-6708 (Pubitemid 36666110)
26. Singh VK, Chader GJ, Rodriguez IR (1998) Structural and comparative analysis of the mouse gene for pigment epithelium-derived factor (PEDF). Mol Vis 4:7
27. Smirnova E, Goldberg EB, Makarova KS et al (2006) ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells. EMBO Rep 7:106-113
28. Takita H, Yoneya S, Gehlbach PL et al (2003) Retinal neuroprotection against ischemic injury mediated by intraocular gene transfer of pigment epithelium-derived factor. Invest Ophthalmol Vis Sci 44:4497-4504 (Pubitemid 37186288)
29. Tombran-Tink J, Chader GG, Johnson LV (1991) PEDF: A pigment epithelium-derived factor with potent neuronal differentiative activity. Exp Eye Res 53:411-414
30. Tombran-Tink J, Shivaram SM, Chader GJ et al (1995) Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity. J Neurosci 15:4992-5003
31. Wu YQ, Notario V, Chader GJ et al (1995) Identification of pigment epithelium-derived factor in the interphotoreceptor matrix of bovine eyes. Protein Expr Purif 6:447-456