Mechanistic studies of 1-aminocyclopropane-1-carboxylate deaminase: Characterization of an unusual pyridoxal 5′-phosphate-dependent reaction

Biochemistry

Volumn 50, Issue 11, 2011, Pages 1950-1962

  Thibodeaux, Christopher J ^a   Liu, Hung Wen ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINOCYCLOPROPANE 1 CARBOXYLATES; 1-AMINO-CYCLOPROPANE- 1-CARBOXYLIC ACIDS; ACTIVE SITE RESIDUES; AMINO GROUP; BOND CLEAVAGES; CHEMICAL MECHANISM; CONSERVED RESIDUES; CYCLOPROPANE RING; CYCLOPROPANE RING OPENING; EXCHANGE REACTION; HYDROGEN BONDING INTERACTIONS; KINETIC PROPERTIES; MECHANISTIC STUDIES; MUTANT ENZYMES; NUCLEOPHILIC CATALYSIS; PLP-DEPENDENT ENZYMES; PSEUDOMONAS SP; RARE EVENT; RATE LIMITING; RATE-LIMITING STEPS; SOLVENT KINETIC ISOTOPE EFFECTS; STRUCTURAL STUDIES; WILD-TYPE ENZYMES;

AMINO ACIDS; CARBOXYLATION; CARBOXYLIC ACIDS; CATALYSIS; CATALYSTS; ENZYMES; HYDROGEN BONDS; ISOTOPES; NUCLEOPHILES; REACTION KINETICS;

PROPANE;

1 AMINOCYCLOPROPANE 1 CARBOXYLIC ACID DEAMINASE; 1 AMINOCYCLOPROPANECARBOXYLIC ACID; CARBON; CYCLOPROPANE; ENZYME; NUCLEOPHILE; PROTON; PYRIDOXAL 5 PHOSPHATE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL BOND; CHEMICAL REACTION; HYDROGEN BOND; NONHUMAN; PH; PRIORITY JOURNAL; PROTON TRANSPORT; PSEUDOMONAS; STEADY STATE; VISCOSITY;

BACTERIAL PROTEINS; BINDING SITES; CARBON-CARBON LYASES; CATALYSIS; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; PSEUDOMONAS; PYRIDOXAL PHOSPHATE;

PSEUDOMONAS SP. ACP;

EID: 79952783619     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101927s     Document Type: Article

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