Isotope effects on enzyme-catalyzed acyl transfer from p-nitrophenyl acetate: Concerted mechanisms and increased hyperconjugation in the transition state

Journal of the American Chemical Society

Volumn 120, Issue 12, 1998, Pages 2703-2709

  Hess, Robert A ^a,b   Hengge, Alvan C ^a,c   Cleland, W W ^a  

^a UNIVERSITY OF WISCONSIN   (United States)

^b BioSeq Inc   (United States)

^c UTAH STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID DERIVATIVE;

ACYLATION; AQUEOUS SOLUTION; ARTICLE; DRUG CONJUGATION; DRUG EFFECT; ENZYME DEGRADATION; ENZYME MECHANISM; HYDROGEN BOND; HYDROLYSIS; NONHUMAN; QUANTUM MECHANICS;

EID: 0032054709     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja973413h     Document Type: Article

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