-
1
-
-
0030665384
-
Biology of cachexia
-
Tisdale MJ: Biology of cachexia. J Natl Cancer Inst 1997, 89:1763-1773
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1763-1773
-
-
Tisdale, M.J.1
-
2
-
-
0016167138
-
Proceedings: Causes of death in cancer patients
-
Inagaki J, Rodriguez V, Bodey GP: Proceedings: causes of death in cancer patients. Cancer 1974, 33:568-573
-
(1974)
Cancer
, vol.33
, pp. 568-573
-
-
Inagaki, J.1
Rodriguez, V.2
Bodey, G.P.3
-
3
-
-
0036830917
-
Cachexia in cancer patients
-
Tisdale MJ: Cachexia in cancer patients. Nat Rev Cancer 2002, 2:862-871
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 862-871
-
-
Tisdale, M.J.1
-
4
-
-
0016696542
-
Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure
-
Corbett TH, Griswold DP Jr., Roberts BJ, Peckham JC, Schabel FM Jr.: Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res 1975, 35:2434-2439
-
(1975)
Cancer Res
, vol.35
, pp. 2434-2439
-
-
Corbett, T.H.1
Griswold Jr., D.P.2
Roberts, B.J.3
Peckham, J.C.4
Schabel Jr., F.M.5
-
5
-
-
77955388009
-
Molecular, cellular and physiological characterization of the cancer cachexia-inducing C26 colon carcinoma in mouse
-
Aulino P, Berardi E, Cardillo VM, Rizzuto E, Perniconi B, Ramina C, Padula F, Spugnini EP, Baldi A, Faiola F, Adamo S, Coletti D: Molecular, cellular and physiological characterization of the cancer cachexia-inducing C26 colon carcinoma in mouse. BMC Cancer 2010, 10:363
-
(2010)
BMC Cancer
, vol.10
, pp. 363
-
-
Aulino, P.1
Berardi, E.2
Cardillo, V.M.3
Rizzuto, E.4
Perniconi, B.5
Ramina, C.6
Padula, F.7
Spugnini, E.P.8
Baldi, A.9
Faiola, F.10
Adamo, S.11
Coletti, D.12
-
6
-
-
10544222015
-
Anti-interleukin-6 receptor antibody prevents muscle atrophy in colon-26 adenocarcinoma-bearing mice with modulation of lysosomal and ATP-ubiquitin-dependent proteolytic pathways
-
DOI 10.1002/(SICI)1097-0215(19961127)68:5<637::AID-IJC14>3.0.CO;2-Z
-
Fujita J, Tsujinaka T, Yano M, Ebisui C, Saito H, Katsume A, Akamatsu K, Ohsugi Y, Shiozaki H, Monden M: Anti-interleukin-6 receptor antibody prevents muscle atrophy in colon-26 adenocarcinoma-bearing mice with modulation of lysosomal and ATP-ubiquitin-dependent proteolytic pathways. Int J Cancer 1996, 68:637-643 (Pubitemid 26414526)
-
(1996)
International Journal of Cancer
, vol.68
, Issue.5
, pp. 637-643
-
-
Fujlta, J.1
Tsujinaka, T.2
Yano, M.3
Eoisui, C.4
Saito, H.5
Katsume, A.6
Akamatsu, K.-I.7
Ohsugi, Y.8
Shiozaki, H.9
Monden, M.10
-
7
-
-
0028850833
-
Molecular analysis of the cytokine network involved in cachexia in colon 26 adenocarcinoma-bearing mice
-
Yasumoto K, Nukaida N, Harada A, Kuno K, Akiyama M, Nakashima E, Fujioka N, Mai M, Kasahara T, Fujimoto-Ouchi K, Mori K, Tanaka Y, Matsushima K: Molecular analysis of the cytokine network involved in cachexia in colon 26 adenocarcinoma-bearing mice. Cancer Res 1995, 55:921-927
-
(1995)
Cancer Res
, vol.55
, pp. 921-927
-
-
Yasumoto, K.1
Nukaida, N.2
Harada, A.3
Kuno, K.4
Akiyama, M.5
Nakashima, E.6
Fujioka, N.7
Mai, M.8
Kasahara, T.9
Fujimoto-Ouchi, K.10
Mori, K.11
Tanaka, Y.12
Matsushima, K.13
-
8
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
Vallabhapurapu S, Karin M: Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 2009, 27:693-733
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
9
-
-
59649104233
-
The IkappaB kinases IKKalpha and IKKbeta are necessary and sufficient for skeletal muscle atrophy
-
Van Gammeren D, Damrauer JS, Jackman RW, Kandarian SC: The IkappaB kinases IKKalpha and IKKbeta are necessary and sufficient for skeletal muscle atrophy. FASEB J 2009, 23:362-370
-
(2009)
FASEB J
, vol.23
, pp. 362-370
-
-
Van Gammeren, D.1
Damrauer, J.S.2
Jackman, R.W.3
Kandarian, S.C.4
-
10
-
-
5444262078
-
IKKbeta/NF-kappaB activation causes severe muscle wasting in mice
-
DOI 10.1016/j.cell.2004.09.027, PII S0092867404009006
-
Cai D, Frantz JD, Tawa NE Jr., Melendez PA, Oh BC, Lidov HG, Hasselgren PO, Frontera WR, Lee J, Glass DJ, Shoelson SE: IKKbeta/ NF-kappaB activation causes severe muscle wasting in mice. Cell 2004, 119:285-298 (Pubitemid 39360909)
-
(2004)
Cell
, vol.119
, Issue.2
, pp. 285-298
-
-
Cai, D.1
Frantz, J.D.2
Tawa Jr., N.E.3
Melendez, P.A.4
Oh, B.-C.5
Lidov, H.G.W.6
Hasselgren, P.-O.7
Frontera, W.R.8
Lee, J.9
Glass, D.J.10
Shoelson, S.E.11
-
11
-
-
61749103068
-
Catabolic mediators of cancer cachexia
-
Tisdale MJ: Catabolic mediators of cancer cachexia. Curr Opin Support Palliat Care 2008, 2:256-2561
-
(2008)
Curr Opin Support Palliat Care
, vol.2
, pp. 256-2561
-
-
Tisdale, M.J.1
-
12
-
-
67649982995
-
Mechanisms of cancer cachexia
-
Tisdale MJ: Mechanisms of cancer cachexia. Physiol Rev 2009, 89:381-410
-
(2009)
Physiol Rev
, vol.89
, pp. 381-410
-
-
Tisdale, M.J.1
-
13
-
-
4043154377
-
Cancer cachexia is regulated by selective targeting of skeletal muscle gene products
-
DOI 10.1172/JCI200420174
-
Acharyya S, Ladner KJ, Nelsen LL, Damrauer J, Reiser PJ, Swoap S, Guttridge DC: Cancer cachexia is regulated by selective targeting of skeletal muscle gene products. J Clin Invest 2004, 114:370-378 (Pubitemid 39071609)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.3
, pp. 370-378
-
-
Acharyya, S.1
Ladner, K.J.2
Nelsen, L.L.3
Damrauer, J.4
Reiser, P.J.5
Swoap, S.6
Guttridge, D.C.7
-
14
-
-
0036837816
-
Altered expression of skeletal muscle myosin isoforms in cancer cachexia
-
Diffee GM, Kalfas K, Al-Majid S, McCarthy DO: Altered expression of skeletal muscle myosin isoforms in cancer cachexia. Am J Physiol Cell Physiol 2002, 283:C1376-C1382 (Pubitemid 35178429)
-
(2002)
American Journal of Physiology - Cell Physiology
, vol.283
, Issue.5
-
-
Diffee, G.M.1
Kalfas, K.2
Al-Majid, S.3
McCarthy, D.O.4
-
15
-
-
27644471080
-
Dystrophin glycoprotein complex dysfunction: A regulatory link between muscular dystrophy and cancer cachexia
-
DOI 10.1016/j.ccr.2005.10.004, PII S1535610805003284
-
Acharyya S, Butchbach ME, Sahenk Z, Wang H, Saji M, Carathers M, Ringel MD, Skipworth RJ, Fearon KC, Hollingsworth MA, Muscarella P, Burghes AH, Rafael-Fortney JA, Guttridge DC: Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia. Cancer Cell 2005, 8:421-432 (Pubitemid 41579836)
-
(2005)
Cancer Cell
, vol.8
, Issue.5
, pp. 421-432
-
-
Acharyya, S.1
Butchbach, M.E.R.2
Sahenk, Z.3
Wang, H.4
Saji, M.5
Carathers, M.6
Ringel, M.D.7
Skipworth, R.J.E.8
Fearon, K.C.H.9
Hollingsworth, M.A.10
Muscarella, P.11
Burghes, A.H.M.12
Rafael-Fortney, J.A.13
Guttridge, D.C.14
-
16
-
-
33845697226
-
Muscle cachexia is regulated by a p53-PW1/Peg3-dependent pathway
-
DOI 10.1101/gad.412606
-
Schwarzkopf M, Coletti D, Sassoon D, Marazzi G: Muscle cachexia is regulated by a p53-PW1/Peg3-dependent pathway. Genes Dev 2006, 20:3440-3452 (Pubitemid 44969161)
-
(2006)
Genes and Development
, vol.20
, Issue.24
, pp. 3440-3452
-
-
Schwarzkopf, M.1
Coletti, D.2
Sassoon, D.3
Marazzi, G.4
-
17
-
-
63349100316
-
Orally available selective melanocortin-4 receptor antagonists stimulate food intake and reduce cancer-induced cachexia in mice
-
Weyermann P, Dallmann R, Magyar J, Anklin C, Hufschmid M, Dubach-Powell J, Courdier-Fruh I, Hennebohle M, Nordhoff S, Mondadori C: Orally available selective melanocortin-4 receptor antagonists stimulate food intake and reduce cancer-induced cachexia in mice. PLoS ONE 2009, 4:e4774
-
(2009)
PLoS ONE
, vol.4
-
-
Weyermann, P.1
Dallmann, R.2
Magyar, J.3
Anklin, C.4
Hufschmid, M.5
Dubach-Powell, J.6
Courdier-Fruh, I.7
Hennebohle, M.8
Nordhoff, S.9
Mondadori, C.10
-
18
-
-
2942599476
-
Indomethacin and ibuprofen preserve gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma
-
DOI 10.1002/nur.20019
-
McCarthy DO, Whitney P, Hitt A, Al-Majid S: Indomethacin and ibuprofen preserve gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma. Res Nurs Health 2004, 27:174-184 (Pubitemid 38748290)
-
(2004)
Research in Nursing and Health
, vol.27
, Issue.3
, pp. 174-184
-
-
McCarthy, D.O.1
Whitney, P.2
Hitt, A.3
Al-Majid, S.4
-
19
-
-
0842347431
-
Potent Antitumor Activity of Interleukin-27
-
DOI 10.1158/0008-5472.CAN-03-2084
-
Hisada M, Kamiya S, Fujita K, Belladonna ML, Aoki T, Koyanagi Y, Mizuguchi J, Yoshimoto T: Potent antitumor activity of interleukin-27. Cancer Res 2004, 64:1152-1156 (Pubitemid 38176923)
-
(2004)
Cancer Research
, vol.64
, Issue.3
, pp. 1152-1156
-
-
Hisada, M.1
Kamiya, S.2
Fujita, K.3
Belladonna, M.L.4
Aoki, T.5
Koyanagi, Y.6
Mizuguchi, J.7
Yoshimoto, T.8
-
20
-
-
69249211187
-
Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice
-
Bonetto A, Penna F, Minero VG, Reffo P, Bonelli G, Baccino FM, Costelli P: Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice. Curr Cancer Drug Targets 2009, 9:608-616
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 608-616
-
-
Bonetto, A.1
Penna, F.2
Minero, V.G.3
Reffo, P.4
Bonelli, G.5
Baccino, F.M.6
Costelli, P.7
-
21
-
-
2142805906
-
Recombinant human erythropoietin attenuates weight loss in a murine cancer cachexia model
-
DOI 10.1007/s00432-003-0526-7
-
van Halteren HK, Bongaerts GP, Verhagen CA, Kamm YJ, Willems JL, Grutters GJ, Koopman JP, Wagener DJ: Recombinant human erythropoietin attenuates weight loss in a murine cancer cachexia model. J Cancer Res Clin Oncol 2004, 130:211-216 (Pubitemid 38553629)
-
(2004)
Journal of Cancer Research and Clinical Oncology
, vol.130
, Issue.4
, pp. 211-216
-
-
Van Halteren, H.K.1
Bongaerts, G.P.A.2
Verhagen, C.A.M.3
Kamm, Y.J.L.4
Willems, J.L.5
Grutters, G.J.6
Koopman, J.P.7
Wagener, D.J.T.8
-
22
-
-
0035225284
-
Cancer-induced fatigue and skeletal muscle wasting: The role of exercise
-
al-Majid S, McCarthy DO: Cancer-induced fatigue and skeletal muscle wasting: the role of exercise. Biol Res Nurs 2001, 2:186-197
-
(2001)
Biol Res Nurs
, vol.2
, pp. 186-197
-
-
Al-Majid, S.1
McCarthy, D.O.2
-
23
-
-
61749097446
-
Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice
-
van Norren K, Kegler D, Argiles JM, Luiking Y, Gorselink M, Laviano A, Arts K, Faber J, Jansen H, van der Beek EM, van Helvoort A: Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice. Br J Cancer 2009, 100:713-722
-
(2009)
Br J Cancer
, vol.100
, pp. 713-722
-
-
Van Norren, K.1
Kegler, D.2
Argiles, J.M.3
Luiking, Y.4
Gorselink, M.5
Laviano, A.6
Arts, K.7
Faber, J.8
Jansen, H.9
Van Der Beek, E.M.10
Van Helvoort, A.11
-
24
-
-
0027196193
-
Mechanisms of experimental cancer cachexia. Local involvement of IL-1 in colon-26 tumor
-
Strassmann G, Masui Y, Chizzonite R, Fong M: Mechanisms of experimental cancer cachexia. Local involvement of IL-1 in colon-26 tumor J Immunol 1993, 150:2341-2345
-
(1993)
J Immunol
, vol.150
, pp. 2341-2345
-
-
Strassmann, G.1
Masui, Y.2
Chizzonite, R.3
Fong, M.4
-
25
-
-
51649098692
-
Metabolomic analysis of cancer cachexia reveals distinct lipid and glucose alterations
-
O'Connell TM, Ardeshirpour F, Asher SA, Winnike J, Yin X, George J, Guttridge DC, He W, Wysong A, Willis MS, Couch ME: Metabolomic analysis of cancer cachexia reveals distinct lipid and glucose alterations. Metabolomics 2008, 4:216-225
-
(2008)
Metabolomics
, vol.4
, pp. 216-225
-
-
O'Connell, T.M.1
Ardeshirpour, F.2
Asher, S.A.3
Winnike, J.4
Yin, X.5
George, J.6
Guttridge, D.C.7
He, W.8
Wysong, A.9
Willis, M.S.10
Couch, M.E.11
-
26
-
-
33947522846
-
Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo
-
DOI 10.1161/01.RES.0000259559.48597.32, PII 0000301220070302000005
-
Willis MS, Ike C, Li L, Wang DZ, Glass DJ, Patterson C: Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo. Circ Res 2007, 100:456-459 (Pubitemid 46673255)
-
(2007)
Circulation Research
, vol.100
, Issue.4
, pp. 456-459
-
-
Willis, M.S.1
Ike, C.2
Li, L.3
Wang, D.-Z.4
Glass, D.J.5
Patterson, C.6
-
27
-
-
66249116681
-
Muscle ring finger 1 mediates cardiac atrophy in vivo
-
Willis MS, Rojas M, Li L, Selzman CH, Tang RH, Stansfield WE, Rodriguez JE, Glass DJ, Patterson C: Muscle ring finger 1 mediates cardiac atrophy in vivo. Am J Physiol Heart Circ Physiol 2009, 296:H997-H1006
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
-
-
Willis, M.S.1
Rojas, M.2
Li, L.3
Selzman, C.H.4
Tang, R.H.5
Stansfield, W.E.6
Rodriguez, J.E.7
Glass, D.J.8
Patterson, C.9
-
28
-
-
36049026136
-
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins
-
DOI 10.1172/JCI31757
-
Li HH, Willis MS, Lockyer P, Miller N, McDonough H, Glass DJ, Patterson C: Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins. J Clin Invest 2007, 117:3211-3223 (Pubitemid 350096979)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3211-3223
-
-
Li, H.-H.1
Willis, M.S.2
Lockyer, P.3
Miller, N.4
McDonough, H.5
Glass, D.J.6
Patterson, C.7
-
29
-
-
67949099043
-
Cardiac muscle ring finger-1 increases susceptibility to heart failure in vivo
-
Willis MS, Schisler JC, Li L, Rodriguez JE, Hilliard EG, Charles PC, Patterson C: Cardiac muscle ring finger-1 increases susceptibility to heart failure in vivo. Circ Res 2009, 105:80-88
-
(2009)
Circ Res
, vol.105
, pp. 80-88
-
-
Willis, M.S.1
Schisler, J.C.2
Li, L.3
Rodriguez, J.E.4
Hilliard, E.G.5
Charles, P.C.6
Patterson, C.7
-
30
-
-
38549102037
-
Cytokines and myocardial dysfunction: State of the art
-
El-Menyar AA: Cytokines and myocardial dysfunction: state of the art. J Card Fail 2008, 14:61-74
-
(2008)
J Card Fail
, vol.14
, pp. 61-74
-
-
El-Menyar, A.A.1
-
31
-
-
0031761451
-
Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy
-
DOI 10.1038/3253
-
Depre C, Shipley GL, Chen W, Han Q, Doenst T, Moore ML, Stepkowski S, Davies PJ, Taegtmeyer H: Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy. Nat Med 1998, 4:1269-1275 (Pubitemid 28512107)
-
(1998)
Nature Medicine
, vol.4
, Issue.11
, pp. 1269-1275
-
-
Depre, C.1
Shipley, G.L.2
Chen, W.3
Han, Q.4
Doenst, T.5
Moore, M.L.6
Stepkowski, S.7
Davies, P.J.A.8
Taegtmeyer, H.9
-
32
-
-
33846966331
-
Differences between pathological and physiological cardiac hypertrophy: Novel therapeutic strategies to treat heart failure
-
McMullen JR, Jennings GL: Differences between pathological and physiological cardiac hypertrophy: novel therapeutic strategies to treat heart failure. Clin Exp Pharmacol Physiol 2007, 34:255-262
-
(2007)
Clin Exp Pharmacol Physiol
, vol.34
, pp. 255-262
-
-
McMullen, J.R.1
Jennings, G.L.2
-
33
-
-
69149111441
-
Effect of curcumin on nuclear factor kappaB signaling pathways in human chronic myelogenous K562 leukemia cells
-
Reuter S, Charlet J, Juncker T, Teiten MH, Dicato M, Diederich M: Effect of curcumin on nuclear factor kappaB signaling pathways in human chronic myelogenous K562 leukemia cells. Ann N Y Acad Sci 2009, 1171:436-447
-
(2009)
Ann N Y Acad Sci
, vol.1171
, pp. 436-447
-
-
Reuter, S.1
Charlet, J.2
Juncker, T.3
Teiten, M.H.4
Dicato, M.5
Diederich, M.6
-
34
-
-
23944456384
-
Skeletal muscle hypertrophy and atrophy signaling pathways
-
Glass DJ: Skeletal muscle hypertrophy and atrophy signaling pathways. Int J Biochem Cell Biol 2005, 37:1974-1984
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 1974-1984
-
-
Glass, D.J.1
-
35
-
-
0035941020
-
Identification of ubiquitin ligases required for skeletal Muscle Atrophy
-
DOI 10.1126/science.1065874
-
Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clarke BA, Poueymirou WT, Panaro FJ, Na E, Dharmarajan K, Pan ZQ, Valenzuela DM, DeChiara TM, Stitt TN, Yancopoulos GD, Glass DJ: Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 2001, 294:1704-1708 (Pubitemid 33104839)
-
(2001)
Science
, vol.294
, Issue.5547
, pp. 1704-1708
-
-
Bodine, S.C.1
Latres, E.2
Baumhueter, S.3
Lai, V.K.-M.4
Nunez, L.5
Clarke, B.A.6
Poueymirou, W.T.7
Panaro, F.J.8
Erqian, N.9
Dharmarajan, K.10
Pan, Z.-Q.11
Valenzuela, D.M.12
Dechiara, T.M.13
Stitt, T.N.14
Yancopoulos, G.D.15
Glass, D.J.16
-
36
-
-
77649162855
-
Sent to destroy: The ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease
-
Willis MS, Townley-Tilson WH, Kang EY, Homeister JW, Patterson C: Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease. Circ Res 2010, 106:463-478
-
(2010)
Circ Res
, vol.106
, pp. 463-478
-
-
Willis, M.S.1
Townley-Tilson, W.H.2
Kang, E.Y.3
Homeister, J.W.4
Patterson, C.5
-
37
-
-
72549108344
-
Seek and destroy: The ubiquitin-proteasome system in cardiac disease
-
Rodriguez JE, Schisler JC, Patterson C, Willis MS: Seek and destroy: the ubiquitin-proteasome system in cardiac disease. Curr Hypertens Rep 2009, 11:396-405
-
(2009)
Curr Hypertens Rep
, vol.11
, pp. 396-405
-
-
Rodriguez, J.E.1
Schisler, J.C.2
Patterson, C.3
Willis, M.S.4
-
38
-
-
38049174964
-
Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease
-
Willis MS, Schisler JC, Patterson C: Appetite for destruction: e3 ubiquitin-ligase protection in cardiac disease. Future Cardiol 2008, 4:65-75
-
(2008)
Future Cardiol
, vol.4
, pp. 65-75
-
-
Willis, M.S.1
Schisler, J.C.2
Patterson, C.3
-
39
-
-
19944374141
-
A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity
-
DOI 10.1038/sj.bjp.0706176
-
Ziegelbauer K, Gantner F, Lukacs NW, Berlin A, Fuchikami K, Niki T, Sakai K, Inbe H, Takeshita K, Ishimori M, Komura H, Murata T, Lowinger T, Bacon KB: A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity. Br J Pharmacol 2005, 145:178-192 (Pubitemid 40756522)
-
(2005)
British Journal of Pharmacology
, vol.145
, Issue.2
, pp. 178-192
-
-
Ziegelbauer, K.1
Gantner, F.2
Lukacs, N.W.3
Berlin, A.4
Fuchikami, K.5
Niki, T.6
Sakai, K.7
Inbe, H.8
Takeshita, K.9
Ishimori, M.10
Komura, H.11
Murata, T.12
Lowinger, T.13
Bacon, K.B.14
-
40
-
-
0034284715
-
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex
-
May MJ, D'Acquisto F, Madge LA, Glockner J, Pober JS, Ghosh S: Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex. Science 2000, 289:1550-1554
-
(2000)
Science
, vol.289
, pp. 1550-1554
-
-
May, M.J.1
D'Acquisto, F.2
Madge, L.A.3
Glockner, J.4
Pober, J.S.5
Ghosh, S.6
-
41
-
-
18544367201
-
NF-kappa B as a therapeutic target in multiple myeloma
-
DOI 10.1074/jbc.M200360200
-
Hideshima T, Chauhan D, Richardson P, Mitsiades C, Mitsiades N, Hayashi T, Munshi N, Dang L, Castro A, Palombella V, Adams J, Anderson KC: NF-kappa B as a therapeutic target in multiple myeloma. J Biol Chem 2002, 277:16639-16647 (Pubitemid 34967682)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.19
, pp. 16639-16647
-
-
Hideshima, T.1
Chauhan, D.2
Richardson, P.3
Mitsiades, C.4
Mitsiades, N.5
Hayashi, T.6
Munshi, N.7
Dang, L.8
Castro, A.9
Palombella, V.10
Adams, J.11
Anderson, K.C.12
-
42
-
-
33748528911
-
Into the heart: The emerging role of the ubiquitin-proteasome system
-
DOI 10.1016/j.yjmcc.2006.07.015, PII S0022282806007243
-
Willis MS, Patterson C: Into the heart: the emerging role of the ubiquitin-proteasome system. J Mol Cell Cardiol 2006, 41:567-579 (Pubitemid 44374543)
-
(2006)
Journal of Molecular and Cellular Cardiology
, vol.41
, Issue.4
, pp. 567-579
-
-
Willis, M.S.1
Patterson, C.2
-
43
-
-
34147131267
-
The bitter end: The ubiquitin-proteasome system and cardiac dysfunction
-
DOI 10.1161/CIRCULATIONAHA.106.649863, PII 0000301720070320000019
-
Patterson C, Ike C, Willis PWt, Stouffer GA, Willis MS: The bitter end: the ubiquitin-proteasome system and cardiac dysfunction. Circulation 2007, 115:1456-1463 (Pubitemid 46648383)
-
(2007)
Circulation
, vol.115
, Issue.11
, pp. 1456-1463
-
-
Patterson, C.1
Ike, C.2
Willis IV, P.W.3
Stouffer, G.A.4
Willis, M.S.5
-
44
-
-
56949095293
-
The ubiquitin-proteasome system in cardiac dysfunction
-
Mearini G, Schlossarek S, Willis MS, Carrier L: The ubiquitin-proteasome system in cardiac dysfunction. Biochim Biophys Acta 2008, 1782:749-763
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 749-763
-
-
Mearini, G.1
Schlossarek, S.2
Willis, M.S.3
Carrier, L.4
-
45
-
-
59449097421
-
Build it up-tear it down: Protein quality control in the cardiac sarcomere
-
Willis MS, Schisler JC, Portbury AL, Patterson C: Build it up-tear it down: protein quality control in the cardiac sarcomere. Cardiovasc Res 2009, 81:439-448
-
(2009)
Cardiovasc Res
, vol.81
, pp. 439-448
-
-
Willis, M.S.1
Schisler, J.C.2
Portbury, A.L.3
Patterson, C.4
-
46
-
-
35348970307
-
IKKbeta inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury
-
DOI 10.1152/ajpheart.00776.2007
-
Moss NC, Stansfield WE, Willis MS, Tang RH, Selzman CH: IKKbeta inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol 2007, 293:H2248-H2253 (Pubitemid 47605868)
-
(2007)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.293
, Issue.4
-
-
Moss, N.C.1
Stansfield, W.E.2
Willis, M.S.3
Tang, R.-H.4
Selzman, C.H.5
-
47
-
-
56249110920
-
Inhibitory kappa B kinase-beta is a target for specific nuclear factor kappa B-mediated delayed cardioprotection
-
Moss NC, Tang RH, Willis M, Stansfield WE, Baldwin AS, Selzman CH: Inhibitory kappa B kinase-beta is a target for specific nuclear factor kappa B-mediated delayed cardioprotection. J Thorac Cardiovasc Surg 2008, 136:1274-1279
-
(2008)
J Thorac Cardiovasc Surg
, vol.136
, pp. 1274-1279
-
-
Moss, N.C.1
Tang, R.H.2
Willis, M.3
Stansfield, W.E.4
Baldwin, A.S.5
Selzman, C.H.6
-
48
-
-
60849113987
-
Inhibition of the classical NF-kappaB pathway prevents osteoclast bone-resorbing activity
-
Soysa NS, Alles N, Shimokawa H, Jimi E, Aoki K, Ohya K: Inhibition of the classical NF-kappaB pathway prevents osteoclast bone-resorbing activity. J Bone Miner Metab 2009, 27:131-139
-
(2009)
J Bone Miner Metab
, vol.27
, pp. 131-139
-
-
Soysa, N.S.1
Alles, N.2
Shimokawa, H.3
Jimi, E.4
Aoki, K.5
Ohya, K.6
-
49
-
-
63749114213
-
Cell-permeable Tat-NBD peptide attenuates rat pancreatitis and acinus cell inflammation response
-
Long YM, Chen K, Liu XJ, Xie WR, Wang H: Cell-permeable Tat-NBD peptide attenuates rat pancreatitis and acinus cell inflammation response. World J Gastroenterol 2009, 15:561-569
-
(2009)
World J Gastroenterol
, vol.15
, pp. 561-569
-
-
Long, Y.M.1
Chen, K.2
Liu, X.J.3
Xie, W.R.4
Wang, H.5
-
50
-
-
2942703810
-
Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo
-
DOI 10.1038/nm1054
-
Jimi E, Aoki K, Saito H, D'Acquisto F, May MJ, Nakamura I, Sudo T, Kojima T, Okamoto F, Fukushima H, Okabe K, Ohya K, Ghosh S: Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo. Nat Med 2004, 10:617-624 (Pubitemid 38796853)
-
(2004)
Nature Medicine
, vol.10
, Issue.6
, pp. 617-624
-
-
Jimi, E.1
Aoki, K.2
Saito, H.3
D'Acquisto, F.4
May, M.J.5
Nakamura, I.6
Sudo, T.7
Kojima, T.8
Okamoto, F.9
Fukushima, H.10
Okabe, K.11
Ohya, K.12
Ghosh, S.13
-
51
-
-
38449110152
-
Cutting edge: The IkappaB kinase (IKK) inhibitor. NEMO-binding domain peptide, blocks inflammatory injury in murine colitis
-
Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M: Cutting edge: the IkappaB kinase (IKK) inhibitor. NEMO-binding domain peptide, blocks inflammatory injury in murine colitis J Immunol 2007, 179:2681-2685
-
(2007)
J Immunol
, vol.179
, pp. 2681-2685
-
-
Shibata, W.1
Maeda, S.2
Hikiba, Y.3
Yanai, A.4
Ohmae, T.5
Sakamoto, K.6
Nakagawa, H.7
Ogura, K.8
Omata, M.9
-
52
-
-
70350545937
-
Local treatment with the selective IkappaB kinase beta inhibitor NEMO-binding domain peptide ameliorates synovial inflammation
-
Tas SW, Vervoordeldonk MJ, Hajji N, May MJ, Ghosh S, Tak PP: Local treatment with the selective IkappaB kinase beta inhibitor NEMO-binding domain peptide ameliorates synovial inflammation. Arthritis Res Ther 2006, 8:R86
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Tas, S.W.1
Vervoordeldonk, M.J.2
Hajji, N.3
May, M.J.4
Ghosh, S.5
Tak, P.P.6
-
53
-
-
56049123409
-
The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene
-
Waddell DS, Baehr LM, van den Brandt J, Johnsen SA, Reichardt HM, Furlow JD, Bodine SC: The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene. Am J Physiol Endocrinol Metab 2008, 295:E785-E797
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
-
-
Waddell, D.S.1
Baehr, L.M.2
Van Den Brandt, J.3
Johnsen, S.A.4
Reichardt, H.M.5
Furlow, J.D.6
Bodine, S.C.7
-
54
-
-
2042425906
-
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
-
DOI 10.1016/S1097-2765(04)00211-4, PII S1097276504002114
-
Stitt TN, Drujan D, Clarke BA, Panaro F, Timofeyva Y, Kline WO, Gonzalez M, Yancopoulos GD, Glass DJ: The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell 2004, 14:395-403 (Pubitemid 38591410)
-
(2004)
Molecular Cell
, vol.14
, Issue.3
, pp. 395-403
-
-
Stitt, T.N.1
Drujan, D.2
Clarke, B.A.3
Panaro, F.4
Timofeyva, Y.5
Kline, W.O.6
Gonzalez, M.7
Yancopoulos, G.D.8
Glass, D.J.9
-
55
-
-
4544293878
-
IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1
-
DOI 10.1152/ajpendo.00073.2004
-
Sacheck JM, Ohtsuka A, McLary SC, Goldberg AL: IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1. Am J Physiol Endocrinol Metab 2004, 287:E591-E601 (Pubitemid 39242684)
-
(2004)
American Journal of Physiology - Endocrinology and Metabolism
, vol.287
, Issue.4
-
-
Sacheck, J.M.1
Ohtsuka, A.2
McLary, S.C.3
Goldberg, A.L.4
-
56
-
-
77951464177
-
MAFbx/Atrogin-1 expression is a poor index of muscle proteolysis
-
Attaix D, Baracos VE: MAFbx/Atrogin-1 expression is a poor index of muscle proteolysis. Curr Opin Clin Nutr Metab Care 2010, 13:223-224
-
(2010)
Curr Opin Clin Nutr Metab Care
, vol.13
, pp. 223-224
-
-
Attaix, D.1
Baracos, V.E.2
-
57
-
-
11144357466
-
IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
-
DOI 10.1016/S0092-8674(04)00302-2, PII S0092867404003022
-
Hu MC, Lee DF, Xia W, Golfman LS, Ou-Yang F, Yang JY, Zou Y, Bao S, Hanada N, Saso H, Kobayashi R, Hung MC: IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 2004, 117:225-237 (Pubitemid 38496242)
-
(2004)
Cell
, vol.117
, Issue.2
, pp. 225-237
-
-
Hu, M.C.-T.1
Lee, D.-F.2
Xia, W.3
Golfman, L.S.4
Ou-Yang, F.5
Yang, J.-Y.6
Zou, Y.7
Bao, S.8
Hanada, N.9
Saso, H.10
Kobayashi, R.11
Hung, M.-C.12
-
58
-
-
34447131534
-
Regulation of mammalian target of rapamycin activity in PTEN-inactive prostate cancer cells by I kappa B kinase alpha
-
DOI 10.1158/0008-5472.CAN-07-1232
-
Dan HC, Adli M, Baldwin AS: Regulation of mammalian target of rapamycin activity in PTEN-inactive prostate cancer cells by I kappa B kinase alpha. Cancer Res 2007, 67:6263-6269 (Pubitemid 47037508)
-
(2007)
Cancer Research
, vol.67
, Issue.13
, pp. 6263-6269
-
-
Dan, H.C.1
Adli, M.2
Baldwin, A.S.3
-
59
-
-
35648958721
-
IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway
-
DOI 10.1128/MCB.01101-07
-
Hutti JE, Turk BE, Asara JM, Ma A, Cantley LC, Abbott DW: IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway. Mol Cell Biol 2007, 27:7451-7461 (Pubitemid 350033652)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.21
, pp. 7451-7461
-
-
Hutti, J.E.1
Turk, B.E.2
Asara, J.M.3
Ma, A.4
Cantley, L.C.5
Abbott, D.W.6
-
60
-
-
62449257012
-
Phosphorylation of p53 by IkappaB kinase 2 promotes its degradation by beta-TrCP
-
Xia Y, Padre RC, De Mendoza TH, Bottero V, Tergaonkar VB, Verma IM: Phosphorylation of p53 by IkappaB kinase 2 promotes its degradation by beta-TrCP. Proc Natl Acad Sci U S A 2009, 106:2629-2634
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2629-2634
-
-
Xia, Y.1
Padre, R.C.2
De Mendoza, T.H.3
Bottero, V.4
Tergaonkar, V.B.5
Verma, I.M.6
-
61
-
-
77957725489
-
JunB transcription factor maintains skeletal muscle mass and promotes hypertrophy
-
Raffaello A, Milan G, Masiero E, Carnio S, Lee D, Lanfranchi G, Goldberg AL, Sandri M: JunB transcription factor maintains skeletal muscle mass and promotes hypertrophy. J Cell Biol 2010, 191:101-113
-
(2010)
J Cell Biol
, vol.191
, pp. 101-113
-
-
Raffaello, A.1
Milan, G.2
Masiero, E.3
Carnio, S.4
Lee, D.5
Lanfranchi, G.6
Goldberg, A.L.7
Sandri, M.8
-
62
-
-
50449101139
-
Evidences of apoptosis during the early phases of soleus muscle atrophy in hindlimb suspended mice
-
Ferreira R, Neuparth MJ, Vitorino R, Appell HJ, Amado F, Duarte JA: Evidences of apoptosis during the early phases of soleus muscle atrophy in hindlimb suspended mice. Physiol Res 2008, 57:601-611
-
(2008)
Physiol Res
, vol.57
, pp. 601-611
-
-
Ferreira, R.1
Neuparth, M.J.2
Vitorino, R.3
Appell, H.J.4
Amado, F.5
Duarte, J.A.6
-
63
-
-
33645831979
-
Hindlimb unloading increases muscle content of cytosolic but not nuclear Id2 and p53 proteins in young adult and aged rats
-
DOI 10.1152/japplphysiol.01012.2005
-
Siu PM, Pistilli EE, Murlasits Z, Alway SE: Hindlimb unloading increases muscle content of cytosolic but not nuclear Id2 and p53 proteins in young adult and aged rats. J Appl Physiol 2006, 100:907-916 (Pubitemid 43671547)
-
(2006)
Journal of Applied Physiology
, vol.100
, Issue.3
, pp. 907-916
-
-
Siu, P.M.1
Pistilli, E.E.2
Murlasits, Z.3
Alway, S.E.4
-
64
-
-
77953745513
-
Molecular mechanisms in aging and current strategies to counteract sarcopenia
-
Sakuma K, Yamaguchi A: Molecular mechanisms in aging and current strategies to counteract sarcopenia. Curr Aging Sci 2010, 3:90-101
-
(2010)
Curr Aging Sci
, vol.3
, pp. 90-101
-
-
Sakuma, K.1
Yamaguchi, A.2
-
65
-
-
77953042829
-
Muscle weakness and atrophy are associated with decreased regenerative capacity and changes in mTOR signaling in skeletal muscles of venerable (18-24-month-old) dystrophic mdx mice
-
Mouisel E, Vignaud A, Hourde C, Butler-Browne G, Ferry A: Muscle weakness and atrophy are associated with decreased regenerative capacity and changes in mTOR signaling in skeletal muscles of venerable (18-24-month-old) dystrophic mdx mice. Muscle Nerve 2010, 41:809-818
-
(2010)
Muscle Nerve
, vol.41
, pp. 809-818
-
-
Mouisel, E.1
Vignaud, A.2
Hourde, C.3
Butler-Browne, G.4
Ferry, A.5
|