메뉴 건너뛰기




Volumn 10, Issue 10, 2010, Pages 769-776

Evaluation of Effect of Triterpenes and Limonoids on Cell Growth, Cell Cycle and Apoptosis in Human Tumor Cell Lines

Author keywords

Anticancer; Apoptosis; Breast adenocarcinoma; Cell cycle arrest; Limonoids; Melanoma; Non small lung cancer; Triterpenes

Indexed keywords

22 HYDROXYTIRUCALLA 7,24 DIENE 2,3-DIONE; 6 ACETOXYGEDUNIN; 6ALPHA ACETOXY 14BETA,15BETA EPOXYAZADIRONE; 7 DEACETOXY 7 OXOGEDUNIN; 7 DEACETOXYGEDUNIN; ANTINEOPLASTIC AGENT; CABRALEADIOL; CEDRELONE; DOXORUBICIN; GEDUNIN; GUYANIN; LIMONOID; OCOTILLONE; ODORADOL; ODORATOL; ODORATONE; TOONACILIN; TRITERPENE; UNCLASSIFIED DRUG;

EID: 79952740999     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152010794728620     Document Type: Article
Times cited : (29)

References (44)
  • 1
    • 33947717002 scopus 로고    scopus 로고
    • Anticancer drugs from nature-natural products as a unique source of new microtubule-stabilizing agents
    • Altmann, K.-H.; Gertsch, J. Anticancer drugs from nature-natural products as a unique source of new microtubule-stabilizing agents. Nat. Prod. Rep., 2007, 24, 327-357.
    • (2007) Nat. Prod. Rep , vol.24 , pp. 327-357
    • Altmann, K.-H.1    Gertsch, J.2
  • 2
    • 36348987143 scopus 로고    scopus 로고
    • The value of natural products to future pharmaceutical discovery
    • Baker, D. D.; Chu, M.; Oza, U.; Rajgarhia, V. The value of natural products to future pharmaceutical discovery. Nat. Prod. Rep., 2007, 24, 1225-1244.
    • (2007) Nat. Prod. Rep , vol.24 , pp. 1225-1244
    • Baker, D.D.1    Chu, M.2    Oza, U.3    Rajgarhia, V.4
  • 3
    • 39149137869 scopus 로고    scopus 로고
    • Plant-derived compounds in clinical trials
    • Saklani, A.; Kutty, S. K. Plant-derived compounds in clinical trials. Drug Discov. Today, 2007, 13, 161-171.
    • (2007) Drug Discov. Today , vol.13 , pp. 161-171
    • Saklani, A.1    Kutty, S.K.2
  • 6
    • 3042848683 scopus 로고    scopus 로고
    • Cell death induction by betulinic acid, ceramide and TRAIL in primary glioblastoma multiforme cells
    • Jeremias, I.; Steiner, H. H.; Debatin, A.; Harold-Mende, C.; Benner, A. Cell death induction by betulinic acid, ceramide and TRAIL in primary glioblastoma multiforme cells. Acta Neurochir. (Wein),2004, 146, 721-729.
    • (2004) Acta Neurochir. (Wein) , vol.146 , pp. 721-729
    • Jeremias, I.1    Steiner, H.H.2    Debatin, A.3    Harold-Mende, C.4    Benner, A.5
  • 7
    • 11844304366 scopus 로고    scopus 로고
    • Betulinic acid induces apoptosis in human chronic myelogenous leukemia (CML) cell line K-562 without altering the levels of Bcr-Abl
    • Gopal, D. V. R.; Narkar, A. A.; Badrinath, Y.; Mishra, K. P.; Joshi, D. S. Betulinic acid induces apoptosis in human chronic myelogenous leukemia (CML) cell line K-562 without altering the levels of Bcr-Abl. Toxicol. Lett., 2005, 155, 343-351.
    • (2005) Toxicol. Lett , vol.155 , pp. 343-351
    • Gopal, D.V.R.1    Narkar, A.A.2    Badrinath, Y.3    Mishra, K.P.4    Joshi, D.S.5
  • 8
    • 0032545386 scopus 로고    scopus 로고
    • Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid
    • Fulda, S.; Scaffidi, C.; Susin, S. A.; Krammer, P.H.; Kroemer, G.; Peter, M. E.; Debatin, K.M. Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid. J. Biol. Chem., 1998, 273, 33942-33948.
    • (1998) J. Biol. Chem , vol.273 , pp. 33942-33948
    • Fulda, S.1    Scaffidi, C.2    Susin, S.A.3    Krammer, P.H.4    Kroemer, G.5    Peter, M.E.6    Debatin, K.M.7
  • 9
    • 0033023669 scopus 로고    scopus 로고
    • Betulinic acid-induced apoptosis in glioma cells: A sequential requirement for protein synthesis, formation of reactive oxygen species, and caspase processing
    • Wick, W., Grimmel, C.; Wagenknecht, B.; Dichgans, J.; Weller, M. Betulinic acid-induced apoptosis in glioma cells: A sequential requirement for protein synthesis, formation of reactive oxygen species, and caspase processing. J. Pharmacol. Exp. Ther., 1999, 289, 1306-1312.
    • (1999) J. Pharmacol. Exp. Ther , vol.289 , pp. 1306-1312
    • Wick, W.1    Grimmel, C.2    Wagenknecht, B.3    Dichgans, J.4    Weller, M.5
  • 10
    • 0031757232 scopus 로고    scopus 로고
    • Betulinic acid inhibits aminopeptidase N activity
    • Melzig, M.F.; Bormann, H. Betulinic acid inhibits aminopeptidase N activity. Planta Med., 1998, 64, 655-657.
    • (1998) Planta Med , vol.64 , pp. 655-657
    • Melzig, M.F.1    Bormann, H.2
  • 14
    • 15944422555 scopus 로고    scopus 로고
    • Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells
    • Xia, L.; Chen, D.; Han, R.; Fang, Q.; Waxman, S.; Jing, Y. Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells. Mol. Cancer Ther., 2005, 4, 381-388.
    • (2005) Mol. Cancer Ther , vol.4 , pp. 381-388
    • Xia, L.1    Chen, D.2    Han, R.3    Fang, Q.4    Waxman, S.5    Jing, Y.6
  • 15
    • 58649104212 scopus 로고    scopus 로고
    • Boswellic acid blocks signal transducers and activators of transcription 3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase SHP-1
    • Kunnumakkara, A. B.; Nair, A. S.; Pandey, B. S. M. K; Aggarwal, B. B. Boswellic acid blocks signal transducers and activators of transcription 3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase SHP-1. Mol. Cancer Res., 2009, 7, 118-128.
    • (2009) Mol. Cancer Res , vol.7 , pp. 118-128
    • Kunnumakkara, A.B.1    Nair, A.S.2    Pandey, B.S.M.K.3    Aggarwal, B.B.4
  • 17
    • 0035826816 scopus 로고    scopus 로고
    • Response of radiochemotherapy-associated cerebral edema to a hytotherapeutic agent, H15
    • Streffer, J. R.; Bitzer, M.; Schabet, M.; Dichgans, J.; Keller, M. Response of radiochemotherapy-associated cerebral edema to a hytotherapeutic agent, H15. Neurology, 2001, 56, 1219-1221.
    • (2001) Neurology , vol.56 , pp. 1219-1221
    • Streffer, J.R.1    Bitzer, M.2    Schabet, M.3    Dichgans, J.4    Keller, M.5
  • 18
    • 0034193436 scopus 로고    scopus 로고
    • Usolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells
    • Subbaramaiah, K.; Michaluart, P.; Sporn, M. B.; Dannenberg, A.J. Usolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells. Cancer Res., 2000, 60, 2399-2404.
    • (2000) Cancer Res , vol.60 , pp. 2399-2404
    • Subbaramaiah, K.1    Michaluart, P.2    Sporn, M.B.3    Dannenberg, A.J.4
  • 19
    • 0028066930 scopus 로고
    • Induction of differentiation in the cultured F9 teratocarcinoma stem cells by triterpene acids
    • Lee, H. Y., Chung, H. Y., Kim, K. H.; Lee, J. J.; Kim, K. W. Induction of differentiation in the cultured F9 teratocarcinoma stem cells by triterpene acids. J. Cancer Res. Clin. Oncol., 1994, 120, 513-518.
    • (1994) J. Cancer Res. Clin. Oncol , vol.120 , pp. 513-518
    • Lee, H.Y.1    Chung, H.Y.2    Kim, K.H.3    Lee, J.J.4    Kim, K.W.5
  • 20
    • 0027162237 scopus 로고
    • Isolation of substances from glossy privet (Ligustrum lucidum Ait.) inhibiting the mutagenicity of benzo[a]pyrene in bacteria
    • Niikawa, M.; Hayashi, H.; Sato, T.; Nagase, H.; Kito H. Isolation of substances from glossy privet (Ligustrum lucidum Ait.) inhibiting the mutagenicity of benzo[a]pyrene in bacteria. Mutat. Res., 1993, 319, 1-9.
    • (1993) Mutat. Res , vol.319 , pp. 1-9
    • Niikawa, M.1    Hayashi, H.2    Sato, T.3    Nagase, H.4    Kito, H.5
  • 22
    • 56349099145 scopus 로고    scopus 로고
    • Maslinic acid, a natural triterpene from Olea europea L.; induces apoptosis in HT29 human cólon-cancer cells via the mitochondrial apoptotic pathway
    • Reyes-Zurita, F.; Rufino-Palomares, E. E.; Lupiáñez, J. A.; Cascante, M. Maslinic acid, a natural triterpene from Olea europea L.; induces apoptosis in HT29 human cólon-cancer cells via the mitochondrial apoptotic pathway. Cancer Lett., 2009, 273, 44-54.
    • (2009) Cancer Lett , vol.273 , pp. 44-54
    • Reyes-Zurita, F.1    Rufino-Palomares, E.E.2    Lupiáñez, J.A.3    Cascante, M.4
  • 23
    • 0034664936 scopus 로고    scopus 로고
    • Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase
    • Mizushina, Y.; Iida, A.; Ohta, K.; Sugawara, F.; Sakagichi, K. Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase. Biochem. J., 2000, 350, 757-763.
    • (2000) Biochem. J , vol.350 , pp. 757-763
    • Mizushina, Y.1    Iida, A.2    Ohta, K.3    Sugawara, F.4    Sakagichi, K.5
  • 25
    • 34249053170 scopus 로고    scopus 로고
    • Triterpenoids from the floral spikes of Betula platyphylla var. japonica and their reversing activity against multidrug-resistant cancer cell
    • Kashiwada, Y.; Sekiya, M.; Yamazaki, K.; Ikeshiro, Y.; Fujioka, T.; Yamagushi, T.; Kitagawa, S.; Takaishi, Y. Triterpenoids from the floral spikes of Betula platyphylla var. japonica and their reversing activity against multidrug-resistant cancer cell. J. Nat. Prod., 2007, 70, 623-627.
    • (2007) J. Nat. Prod , vol.70 , pp. 623-627
    • Kashiwada, Y.1    Sekiya, M.2    Yamazaki, K.3    Ikeshiro, Y.4    Fujioka, T.5    Yamagushi, T.6    Kitagawa, S.7    Takaishi, Y.8
  • 26
    • 60549097729 scopus 로고    scopus 로고
    • Isolation of limonoidsfrom seeds of Carapa guianensis Aublet (Meliaceae) by high-speed countercurrent chromatography
    • Silva, V. P.; Oliveira, R.R.; Figueiredo, M.R. Isolation of limonoidsfrom seeds of Carapa guianensis Aublet (Meliaceae) by high-speed countercurrent chromatography. Phytochem. Anal., 2008, 26, 77-81.
    • (2008) Phytochem. Anal , vol.26 , pp. 77-81
    • Silva, V.P.1    Oliveira, R.R.2    Figueiredo, M.R.3
  • 31
    • 64349096428 scopus 로고    scopus 로고
    • Isolation ofsecondary metabolites from Hortia oreadica (Rutaceae) leaves throgh highspeed counter current chromatography
    • Severina, V. G.; Cazal, C. M.; Forim, C. M.; Silva, M. F.; Rodrigues-Filho, E.; Fernandes, J. B.; Vieira, P. C. Isolation ofsecondary metabolites from Hortia oreadica (Rutaceae) leaves throgh highspeed counter current chromatography. J. Chromatogr. A, 2009, 1216, 4275-4281.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 4275-4281
    • Severina, V.G.1    Cazal, C.M.2    Forim, C.M.3    Silva, M.F.4    Rodrigues-Filho, E.5    Fernandes, J.B.6    Vieira, P.C.7
  • 35
    • 40349084065 scopus 로고    scopus 로고
    • A new sesquiterpene and other terpenoid constituents of Chisocheton penduliflorus
    • Phongmaykin, J.; Kumamoto, T.; Ishikawa, T.; Suttisri, R.; Saifah, E. A new sesquiterpene and other terpenoid constituents of Chisocheton penduliflorus. Arch. Pharm. Res., 2008, 31, 21-27.
    • (2008) Arch. Pharm. Res , vol.31 , pp. 21-27
    • Phongmaykin, J.1    Kumamoto, T.2    Ishikawa, T.3    Suttisri, R.4    Saifah, E.5
  • 36
    • 0027075326 scopus 로고
    • Toxicity of the limonoids allelochemical cedrelone to noctuid larvae
    • Koul, O.; Isman, M. B. Toxicity of the limonoids allelochemical cedrelone to noctuid larvae. Entomol. Exp. Appl., 1992, 64, 281-287.
    • (1992) Entomol. Exp. Appl , vol.64 , pp. 281-287
    • Koul, O.1    Isman, M.B.2
  • 39
    • 56549109932 scopus 로고    scopus 로고
    • Antimalarial, antimycobacterial and cytotoxic limonoids from Chisocheton siamensis
    • Maneerat, W.; Laphookhieo, Koysomboon, S.; Chantrapromma, K. Antimalarial, antimycobacterial and cytotoxic limonoids from Chisocheton siamensis. Phytomedicine, 2008, 15, 1130-1134.
    • (2008) Phytomedicine , vol.15 , pp. 1130-1134
    • Maneerat, W.1    Laphookhieo, K.S.2    Chantrapromma, K.3
  • 40
    • 54549105458 scopus 로고    scopus 로고
    • Gedunin, a novel Hsp90 inhibitor: Semisynthesis of derivativesand preliminary structure-activity relationships
    • Brandt, G. E. L.; Schmidt, M. D.; Prisinzano, T. E.; Blagg, B. S. J. Gedunin, a novel Hsp90 inhibitor: semisynthesis of derivativesand preliminary structure-activity relationships. J. Med. Chem., 2008, 51, 6495-6502.
    • (2008) J. Med. Chem , vol.51 , pp. 6495-6502
    • Brandt, G.E.L.1    Schmidt, M.D.2    Prisinzano, T.E.3    Blagg, B.S.J.4
  • 43
    • 70350317603 scopus 로고    scopus 로고
    • Induction of apoptosis by lupeol in human epidermoid carcinoma A431 cells through regulation of mitochondrial, Akt/PKB and NFkappaB signaling pathways
    • Prasad, S.; Madan, E.; Nigam, N.; Roy, P.; George, J.; Shukla, Y.; Induction of apoptosis by lupeol in human epidermoid carcinoma A431 cells through regulation of mitochondrial, Akt/PKB and NFkappaB signaling pathways. Cancer Biol. Ther., 2009, 8, 1632-1639.
    • (2009) Cancer Biol. Ther , vol.8 , pp. 1632-1639
    • Prasad, S.1    Madan, E.2    Nigam, N.3    Roy, P.4    George, J.5    Shukla, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.