Interleukin-15:Interleukin-15 receptor scaffold for creation of multivalent targeted immune molecules

Protein Engineering, Design and Selection

Volumn 24, Issue 4, 2011, Pages 373-383

  Wong, Richard L ^a   Liu, Bai ^b   Zhu, Xiaoyun ^b   You, Lijing ^b   Kong, Lin ^b   Han, Kai Ping ^b   Lee, Hyung Il ^b   Chavaillaz, Pierre Andre ^b   Jin, Moonsoo ^a   Wang, Yi ^a   Rhode, Peter R ^b   Wong, Hing C ^b  

^a Cornell University   (United States)

^b ALTOR BIOSCIENCE CORPORATION   (United States)

Author keywords

bispecific fusion protein; CD8; interleukin 15; protein scaffold; T cell receptor

Indexed keywords

AFFINITY INTERACTIONS; ANTIGEN BINDING; ANTIGEN PRESENTING CELLS; ANTIGEN-BINDING ACTIVITIES; BIOLOGICAL ACTIVITIES; CD8; CYTOKINES; EXTRACELLULAR; FUSION PROTEINS; HUMAN INTERLEUKIN; IMMUNE EFFECTOR CELLS; INTERLEUKIN-15; MULTI DOMAINS; RECEPTOR BINDING; T CELL RECEPTOR;

ANTIBODIES; ANTIGENS; CELL MEMBRANES; COMPLEXATION; MOLECULES;

SCAFFOLDS (BIOLOGY);

HETERODIMER; HYBRID PROTEIN; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR ALPHA; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL PROLIFERATION; COMPLEX FORMATION; CYTOTOXIC T LYMPHOCYTE; EXPRESSION VECTOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TARGETING; RETROVIRUS; VIRUS RECOMBINANT;

CELLS, CULTURED; HUMANS; INTERLEUKIN-15; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, INTERLEUKIN-15; RECOMBINANT FUSION PROTEINS;

EID: 79952658018     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzq116     Document Type: Article

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