Targeting IL-15 receptor-bearing cells with an antagonist mutant IL-15/Fc protein prevents disease development and progression in murine collagen-induced arthritis

Journal of Immunology

Volumn 173, Issue 9, 2004, Pages 5818-5826

  Ferrari Lacraz, Sylvie ^a,d   Zanelli, Eric ^b   Neuberg, Manfred ^b   Donskoy, Elina ^b   Kim, Yon Su ^a,e   Zheng, Xin Xiao ^a   Hancock, Wayne W ^c   Maslinski, Wlodzimierz ^a,f   Li, Xian Chang ^a   Strom, Terry B ^a   Moll, Thomas ^a,g  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b Cardion AG   (Germany)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d University Hospital ^*  (Switzerland)

^e Seoul National University   (South Korea)

^f INSTITUTE OF RHEUMATOLOGY   (Poland)

^g San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; COLLAGEN TYPE 2; CRB 15 PROTEIN; CYTOKINE; FC RECEPTOR; HYBRID PROTEIN; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; BONE EROSION; CARTILAGE DEGENERATION; COLLAGEN INDUCED ARTHRITIS; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DRUG MECHANISM; IMMUNE RESPONSE; IMMUNIZATION; INFLAMMATION; JOINT DESTRUCTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; RELAPSE; RHEUMATOID ARTHRITIS; SYNOVITIS; T LYMPHOCYTE;

EID: 6344269986     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.9.5818     Document Type: Article

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