GDNF-induced osteopontin from Müller glial cells promotes photoreceptor survival in the Pde6brd1 mouse model of retinal degeneration

GLIA

Volumn 59, Issue 5, 2011, Pages 821-832

  Del Río, Patricia ^a   Irmler, Martin ^a   Arango González, Blanca ^b   Favor, Jack ^a   Bobe, Caroline ^a   Bartsch, Udo ^c   Vecino, Elena ^d   Beckers, Johannes ^a,e   Hauck, Stefanie M ^a   Ueffing, Marius ^a,b  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^d UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Apoptosis; Illumina transcriptome arrays; Neuron glia interaction; Neuroprotection; OPN; PI3K; Retinitis pigmentosa

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLYCOPROTEIN; OSTEOPONTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT OSTEOPONTIN; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVATION; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; GLIA CELL; HUMAN; MOUSE; MUELLER CELL; NEUROPROTECTION; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA DEGENERATION; RNA ISOLATION; SWINE; UPREGULATION; WILD TYPE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL SURVIVAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MICE; MICE, TRANSGENIC; NEUROGLIA; OSTEOPONTIN; PHOTORECEPTOR CELLS, VERTEBRATE; RETINAL DEGENERATION;

EID: 79952653281     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.21155     Document Type: Article

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