PPARγ activation redirects macrophage cholesterol from fecal excretion to adipose tissue uptake in mice via SR-BI

Biochemical Pharmacology

Volumn 81, Issue 7, 2011, Pages 934-941

  Toh, Sue Anne ^a,b   Millar, John S ^a,b   Billheimer, Jeffrey ^a,b   Fuki, Ilia ^b   Naik, Snehal U ^b   Macphee, Colin ^c   Walker, Max ^c   Rader, Daniel J ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c GLAXOSMITHKLINE   (United States)

Author keywords

Adipose tissue; HDL; PPAR ; Reverse cholesterol transport; SR BI

Indexed keywords

2 [1 CARBOXY 2 [4 [2 (5 METHYL 2 PHENYL 4 OXAZOLYL)ETHOXY]PHENYL]ETHYLAMINO]BENZOIC ACID METHYL ESTER; ABC TRANSPORTER A1; CHOLESTEROL H 3; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RADIOISOTOPE; SCAVENGER RECEPTOR BI; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LABELING; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG TARGETING; FECES ANALYSIS; FEMALE; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LIPID DEGRADATION; MACROPHAGE; MACROPHAGE FUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; WILD TYPE;

ADIPOSE TISSUE; ANIMALS; CELL LINE; CHOLESTEROL; FECES; FEMALE; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXAZOLES; PPAR GAMMA; SCAVENGER RECEPTORS, CLASS B; TYROSINE;

EID: 79952575159     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.01.012     Document Type: Article

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