LMP1 antagonizes WNT/β-catenin signalling through inhibition of WTX and promotes nasopharyngeal dysplasia but not tumourigenesis in LMP1 B95-8 transgenic mice

Journal of Pathology

Volumn 223, Issue 5, 2011, Pages 574-583

  Zhang, QingLing ^a   Yu, LiNa ^a   Liu, Li ^a   Wang, Shuang ^a   Yang, YuFang ^a   Ding, Yi ^a   Divakaran, Jeevan ^a   Li, Xin ^a   Ding, YanQing ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

catenin; E cadherin; Epstein Barr virus (EBV); Latent membrane protein 1 (LMP1); Transgenic mouse; Wilms' tumour gene on the X chromosome (WTX)

Indexed keywords

BETA CATENIN; LATENT MEMBRANE PROTEIN 1; SMALL INTERFERING RNA; UVOMORULIN; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM; EPITHELIUM DYSPLASIA; FEMALE; GENE SILENCING; HISTOPATHOLOGY; IN VIVO STUDY; MOUSE; NASOPHARYNGEAL DYSPLASIA; NASOPHARYNX; NONHUMAN; OROPHARYNGEAL DYSPLASIA; OROPHARYNX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TUMOR SUPPRESSOR GENE;

ANIMALS; BETA CATENIN; CADHERINS; GENES, WILMS TUMOR; GENETIC VECTORS; HUMANS; LENTIVIRUS; MICE; MICE, TRANSGENIC; NASOPHARYNGEAL NEOPLASMS; NEOPLASM PROTEINS; PRECANCEROUS CONDITIONS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS; VIRAL MATRIX PROTEINS; WNT PROTEINS;

EID: 79952566520     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2820     Document Type: Article

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