메뉴 건너뛰기




Volumn 117, Issue 1, 2011, Pages 38-47

Gadolinium-induced oxidative stress triggers endoplasmic reticulum stress in rat cortical neurons

Author keywords

Endoplasmic reticulum stress; Gadolinium; Neurotoxicity; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; CCAAT ENHANCER BINDING PROTEIN; GADOLINIUM; INOSITOL; REACTIVE OXYGEN METABOLITE; X BOX BINDING PROTEIN 1;

EID: 79952552796     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.07162.x     Document Type: Article
Times cited : (82)

References (53)
  • 1
    • 38349103948 scopus 로고    scopus 로고
    • Dermal inorganic gadolinium concentrations: Evidence for in vivo transmetallation and long-term persistence in nephrogenic systemic fibrosis
    • Abraham J. L., Thakral C., Skov L., Rossen K. and Marckman P. (2008) Dermal inorganic gadolinium concentrations: evidence for in vivo transmetallation and long-term persistence in nephrogenic systemic fibrosis. Br. J. Dermatol. 158, 273-280.
    • (2008) Br. J. Dermatol. , vol.158 , pp. 273-280
    • Abraham, J.L.1    Thakral, C.2    Skov, L.3    Rossen, K.4    Marckman, P.5
  • 2
    • 0035066984 scopus 로고    scopus 로고
    • Basic experimental studies and clinical aspects of gadolinium salts and chelates
    • Adding L. C., Gerard L. B. and Lars E. G. (2006) Basic experimental studies and clinical aspects of gadolinium salts and chelates. Cardiovasc. Drug Rev. 19, 41-56.
    • (2006) Cardiovasc. Drug Rev. , vol.19 , pp. 41-56
    • Adding, L.C.1    Gerard, L.B.2    Lars, E.G.3
  • 3
    • 30444432257 scopus 로고    scopus 로고
    • CHOP plays a pivotal role in the astrocyte death induced by oxygen and glucose deprivation
    • DOI 10.1002/glia.20242
    • Benavides A., Pastor D., Santos P., Tranque P. and Calvo S. (2005) CHOP plays a pivotal role in the astrocyte death induced by oxygen and glucose deprivation. Glia 52, 261-275. (Pubitemid 43076219)
    • (2005) GLIA , vol.52 , Issue.4 , pp. 261-275
    • Benavides, A.1    Pastor, D.2    Santos, P.3    Tranque, P.4    Calvo, S.5
  • 4
    • 0033782015 scopus 로고    scopus 로고
    • Dynamic interaction of BiP and the ER stress transducers in the unfolded protein response
    • Bertolotti A., Zhang Y., Hendershot L., Hardling H. and Ron D. (2000) Dynamic interaction of BiP and the ER stress transducers in the unfolded protein response. Nat. Cell Biol. 2, 326-332.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 326-332
    • Bertolotti, A.1    Zhang, Y.2    Hendershot, L.3    Hardling, H.4    Ron, D.5
  • 5
    • 38149090207 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis
    • Biagioli M., Pifferi S., Ragghianti M., Bucci S., Rizzuto R. and Pinton P. (2008) Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis. Cell Calcium 43, 184-195.
    • (2008) Cell Calcium , vol.43 , pp. 184-195
    • Biagioli, M.1    Pifferi, S.2    Ragghianti, M.3    Bucci, S.4    Rizzuto, R.5    Pinton, P.6
  • 6
    • 43049114497 scopus 로고    scopus 로고
    • Nephrogenic systemic fibrosis associated with gadolinium based contrast agents: A summary of the medical literature reporting
    • Broome D. R. (2008) Nephrogenic systemic fibrosis associated with gadolinium based contrast agents: a summary of the medical literature reporting. Eur. J. Radiol. 66, 230-234.
    • (2008) Eur. J. Radiol. , vol.66 , pp. 230-234
    • Broome, D.R.1
  • 7
    • 0029060701 scopus 로고
    • Carbonic anhydrase III. Oxidative modification in vivo and loss of phosphatase activity during aging
    • Cabiscol E. and Levine R. L. (1995) Carbonic anhydrase III. Oxidative modification in vivo and loss of phosphatase activity during aging. J. Biol. Chem. 270, 14742-14747.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14742-14747
    • Cabiscol, E.1    Levine, R.L.2
  • 9
    • 4744344331 scopus 로고    scopus 로고
    • Cerebral ischemia and the unfolded protein response
    • DOI 10.1111/j.1471-4159.2004.02703.x
    • DeGracia D. J. and Montie H. L. (2004) Cerebral ischemia and the unfolded protein response. J. Neurochem. 91, 1-8. (Pubitemid 39314931)
    • (2004) Journal of Neurochemistry , vol.91 , Issue.1 , pp. 1-8
    • DeGracia, D.J.1    Montie, H.L.2
  • 10
    • 77649192183 scopus 로고    scopus 로고
    • Endoplasmic reticulum calcium release potentiates the ER stress and cell death caused by an oxidative stress in MCF-7 cells
    • Dejeans N., Tajeddine N., Beck R., Verrax J., Taper H., Gailly P. and Calderon P. B. (2010) Endoplasmic reticulum calcium release potentiates the ER stress and cell death caused by an oxidative stress in MCF-7 cells. Biochem. Pharmacol. 79, 1221-1230.
    • (2010) Biochem. Pharmacol. , vol.79 , pp. 1221-1230
    • Dejeans, N.1    Tajeddine, N.2    Beck, R.3    Verrax, J.4    Taper, H.5    Gailly, P.6    Calderon, P.B.7
  • 11
    • 0023576056 scopus 로고
    • Voltage gating in VDAC is markedly inhibited by micromolar quantities of aluminum
    • Dill E. T., Holden M. J. and Colombini M. (1987) Voltage gating in VDAC is markedly inhibited by micromolar quantities of aluminum. J. Membr. Biol. 99, 187-196.
    • (1987) J. Membr. Biol. , vol.99 , pp. 187-196
    • Dill, E.T.1    Holden, M.J.2    Colombini, M.3
  • 12
    • 71349088127 scopus 로고    scopus 로고
    • 3+on mitochondrial permeability transition pore depending on the concentration
    • 3+ on mitochondrial permeability transition pore depending on the concentration. Biometals 22, 917-926.
    • (2009) Biometals , vol.22 , pp. 917-926
    • Dong, S.1    Zhao, Y.2    Liu, H.3    Yang, X.4    Wang, K.5
  • 13
    • 7044286177 scopus 로고    scopus 로고
    • Manganese exposure and induced oxidative stress in the rat brain
    • DOI 10.1016/j.scitotenv.2004.04.044, PII S0048969704003869, Highway and Urban Pollution
    • Erikson K. M., Dobson A. W., Dorman D. C. and Aschner M. (2004) Manganese exposure and induced oxidative stress in the rat brain. Sci.Total Environ. 334-335, 409-416. (Pubitemid 39420358)
    • (2004) Science of the Total Environment , vol.334-335 , pp. 409-416
    • Erikson, K.M.1    Dobson, A.W.2    Dorman, D.C.3    Aschner, M.4
  • 15
    • 77953538985 scopus 로고    scopus 로고
    • Impaired mitochondrial function and oxidative stress in rat cortical neurons: Implications for gadolinium-induced neurotoxicity
    • Feng X. D., Xia Q., Yuan L., Yang X. D. and Wang K. (2010) Impaired mitochondrial function and oxidative stress in rat cortical neurons: implications for gadolinium-induced neurotoxicity. Neurotoxicology 31, 391-398.
    • (2010) Neurotoxicology , vol.31 , pp. 391-398
    • Feng, X.D.1    Xia, Q.2    Yuan, L.3    Yang, X.D.4    Wang, K.5
  • 16
    • 79251523539 scopus 로고    scopus 로고
    • Gadolinium triggers unfolded protein responses (UPRs) in primary cultured rat cortical astrocytes via promotion of an influx of extracellular Ca(2 + )
    • Feng X. D., Xia Q., Yuan L., Huang H. F., Yang X. D. and Wang K. (2011) Gadolinium triggers unfolded protein responses (UPRs) in primary cultured rat cortical astrocytes via promotion of an influx of extracellular Ca(2 + ). Cell Biol. Toxicol. 27, 1-2.
    • (2011) Cell Biol. Toxicol. , vol.27 , pp. 1-2
    • Feng, X.D.1    Xia, Q.2    Yuan, L.3    Huang, H.F.4    Yang, X.D.5    Wang, K.6
  • 17
    • 33744534027 scopus 로고    scopus 로고
    • The therapeutic application of lanthanides
    • Fricker S. P. (2006) The therapeutic application of lanthanides. Chem. Soc. Rev. 35, 524-533.
    • (2006) Chem. Soc. Rev. , vol.35 , pp. 524-533
    • Fricker, S.P.1
  • 18
    • 0035872485 scopus 로고    scopus 로고
    • Gadolinium in human glioblastoma cells for gadolinium neutron capture therapy
    • Gelsomina D. S., Patrizia C., Roberto P. et al. (2001) Gadolinium in human glioblastoma cells for gadolinium neutron capture therapy. Cancer Res. 61, 4272-4277.
    • (2001) Cancer Res. , vol.61 , pp. 4272-4277
    • Gelsomina, D.S.1    Patrizia, C.2    Roberto, P.3
  • 19
    • 0034967586 scopus 로고    scopus 로고
    • Abnormalities in oxidative processes in non-neuronal tissues from patients with Alzheimer's disease
    • Gibson G. E. and Zhang H. (2001) Abnormalities in oxidative processes in non-neuronal tissues from patients with Alzheimer's disease. J. Alzheimers Dis. 3, 329-338. (Pubitemid 32577637)
    • (2001) Journal of Alzheimer's Disease , vol.3 , Issue.3 , pp. 329-338
    • Gibson, G.E.1    Zhang, H.2
  • 20
    • 0041568574 scopus 로고    scopus 로고
    • Induction of GRP78 by ischemic preconditioning reduces endoplasmic reticulum stress and prevents delayed neuronal cell death
    • Hayashi T., Saito A., Okuno S., Ferrand-Drake M. and Chan P. H. (2003) Induction of GRP78 by ischemic preconditioning reduces endoplasmic reticulum stress and prevents delayed neuronal cell death. J. Cereb. Blood Flow Metab. 23, 949-961.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 949-961
    • Hayashi, T.1    Saito, A.2    Okuno, S.3    Ferrand-Drake, M.4    Chan, P.H.5
  • 21
    • 11844282198 scopus 로고    scopus 로고
    • Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons
    • Hayashi T., Saito A., Okuno S., Ferrand-Drake M., Dodd R. L. and Chan P. H. (2005) Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons. J. Cereb. Blood Flow. Metab. 25, 41-53.
    • (2005) J. Cereb. Blood Flow. Metab. , vol.25 , pp. 41-53
    • Hayashi, T.1    Saito, A.2    Okuno, S.3    Ferrand-Drake, M.4    Dodd, R.L.5    Chan, P.H.6
  • 22
    • 33748707584 scopus 로고    scopus 로고
    • Oxidative stress-triggered unfolded protein response is upstream of intrinsic cell death evoked by parkinsonian mimetics
    • DOI 10.1111/j.1471-4159.2006.04025.x
    • Holtz W. A., Turetzky J. M., Jong Y. J. and O'Malley K. L. (2006) Oxidative stress-triggered unfolded protein response is upstream of intrinsic cell death evoked by parkinsonian mimetics. J. Neurochem. 99, 54-69. (Pubitemid 44395130)
    • (2006) Journal of Neurochemistry , vol.99 , Issue.1 , pp. 54-69
    • Holtz, W.A.1    Turetzky, J.M.2    Jong, Y.-J.I.3    O'Malley, K.L.4
  • 23
    • 38449090079 scopus 로고    scopus 로고
    • Neurotoxic potential of depleted uranium effects in primary cortical neuron cultures and in Caenorhabditis elegans
    • Jiang G. C. T., Tidwell K., McLaughlin B. A., Cai J., Gupta R. C., Milatovic D., Nass R. and Aschner M. (2007) Neurotoxic potential of depleted uranium effects in primary cortical neuron cultures and in Caenorhabditis elegans. Toxicol. Sci. 99, 553-565.
    • (2007) Toxicol. Sci. , vol.99 , pp. 553-565
    • Jiang, G.C.T.1    Tidwell, K.2    McLaughlin, B.A.3    Cai, J.4    Gupta, R.C.5    Milatovic, D.6    Nass, R.7    Aschner, M.8
  • 24
    • 0037423392 scopus 로고    scopus 로고
    • Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth
    • Jung S., Mühle A., Schaefer M., Strotmann R., Schultz G. and Plant T. D. (2003) Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth. J. Biol. Chem. 278, 3562-3571.
    • (2003) J. Biol. Chem. , vol.278 , pp. 3562-3571
    • Jung, S.1    Mühle, A.2    Schaefer, M.3    Strotmann, R.4    Schultz, G.5    Plant, T.D.6
  • 27
    • 0025811786 scopus 로고
    • Competitive inhibition of a set of endoplasmic reticulum protein genes (GRP78, GRP94, and ERp72) retards cell growth and lowers viability after ionophore treatment
    • Li X. A. and Lee A. S. (1991) Competitive inhibition of a set of endoplasmic reticulum protein genes (GRP78, GRP94, and ERp72) retards cell growth and lowers viability after ionophore treatment. Mol. Cell. Biol. 11, 3446-3453.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3446-3453
    • Li, X.A.1    Lee, A.S.2
  • 28
    • 0042208330 scopus 로고    scopus 로고
    • 3+ induced changes in mitochondrial structure, membrane permeability, cytochrome c release and intracellular ROS level
    • 3+ induced changes in mitochondrial structure, membrane permeability, cytochrome c release and intracellular ROS level. Chem. Biol. Interact. 146, 27-37.
    • (2003) Chem. Biol. Interact. , vol.146 , pp. 27-37
    • Liu, H.1    Yuan, L.2    Yang, X.3    Wang, K.4
  • 29
    • 0037349147 scopus 로고    scopus 로고
    • Apoptosis and necrosis: Two distinct events induced by cadmium in cortical neurons in culture
    • López E., Figueroa S., Oset-Gasque M. J. and González M. P. (2003) Apoptosis and necrosis: two distinct events induced by cadmium in cortical neurons in culture. Br. J. Pharmacol. 138, 901-911.
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 901-911
    • López, E.1    Figueroa, S.2    Oset-Gasque, M.J.3    González, M.P.4
  • 30
    • 33749492425 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress signaling in disease
    • Marciniak S. J. and Ron D. (2006) Endoplasmic reticulum stress signaling in disease. Physiol. Rev. 86, 1133-1149.
    • (2006) Physiol. Rev. , vol.86 , pp. 1133-1149
    • Marciniak, S.J.1    Ron, D.2
  • 31
    • 33748049106 scopus 로고    scopus 로고
    • Nephrogenic systemic fibrosis: Suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging
    • Marckmann P., Skov L., Rossen K., Dupont A., Damholt M. B., Heaf J. G. and Thomsen H. S. (2006) Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging. J. Am. Soc. Nephrol. 17, 2359-2362.
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 2359-2362
    • Marckmann, P.1    Skov, L.2    Rossen, K.3    Dupont, A.4    Damholt, M.B.5    Heaf, J.G.6    Thomsen, H.S.7
  • 33
    • 58349088980 scopus 로고    scopus 로고
    • Inhibition of alpha-mannosidase attenuates endoplasmic reticulum stress induced neuronal cell death
    • Miyake K. and Nagai K. (2009) Inhibition of alpha-mannosidase attenuates endoplasmic reticulum stress induced neuronal cell death. Neurotoxicology 30, 144-150.
    • (2009) Neurotoxicology , vol.30 , pp. 144-150
    • Miyake, K.1    Nagai, K.2
  • 35
    • 62549147038 scopus 로고    scopus 로고
    • The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells
    • Nishitsuji K., Tomiyama T., Ishibashi K., Ito K., Teraoka R., Lambert M. P., Klein W. L. and Mori H. (2009) The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells. Am. J. Pathol. 174, 957-969.
    • (2009) Am. J. Pathol. , vol.174 , pp. 957-969
    • Nishitsuji, K.1    Tomiyama, T.2    Ishibashi, K.3    Ito, K.4    Teraoka, R.5    Lambert, M.P.6    Klein, W.L.7    Mori, H.8
  • 37
    • 0043037253 scopus 로고    scopus 로고
    • Endoplasmic reticulum: A primary target in various acute disorders and degenerative diseases of the brain
    • Paschen W. (2003) Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain. Cell Calcium 34, 365-383.
    • (2003) Cell Calcium , vol.34 , pp. 365-383
    • Paschen, W.1
  • 38
    • 34250025385 scopus 로고    scopus 로고
    • Gadlinium use in patients with kidney disease: A cause of concern
    • Perazella M. A. and Rodby R. A. (2007) Gadlinium use in patients with kidney disease: a cause of concern. Semin. Dial. 20, 179-185.
    • (2007) Semin. Dial. , vol.20 , pp. 179-185
    • Perazella, M.A.1    Rodby, R.A.2
  • 39
    • 39649114320 scopus 로고    scopus 로고
    • Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins
    • Reijonen S., Putkonen N., Nørremølle A., Lindholm D. and Korhonen L. (2008) Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins. Exp. Cell Res. 314, 950-960.
    • (2008) Exp. Cell Res. , vol.314 , pp. 950-960
    • Reijonen, S.1    Putkonen, N.2    Nørremølle, A.3    Lindholm, D.4    Korhonen, L.5
  • 40
    • 5444222234 scopus 로고    scopus 로고
    • XBP1: A link between the unfolded protein response,lipid biosynthesis, and biogenesis of the endoplasmic reticulum
    • Rungtawan S., Suzanne J., Kazutoshi M. and Joseph W. B. (2004) XBP1: a link between the unfolded protein response,lipid biosynthesis, and biogenesis of the endoplasmic reticulum. J. Cell Biol. 167, 35-41.
    • (2004) J. Cell Biol. , vol.167 , pp. 35-41
    • Rungtawan, S.1    Suzanne, J.2    Kazutoshi, M.3    Joseph, W.B.4
  • 41
    • 0347285295 scopus 로고    scopus 로고
    • A trip to the ER: Coping with stress
    • DOI 10.1016/j.tcb.2003.11.001
    • Rutkowski D. T. and Kaufman R. J. (2004) A trip to the ER: coping with stress. Trends Cell Biol. 14, 20-28. (Pubitemid 38076857)
    • (2004) Trends in Cell Biology , vol.14 , Issue.1 , pp. 20-28
    • Rutkowski, D.T.1    Kaufman, R.J.2
  • 42
    • 0030020028 scopus 로고    scopus 로고
    • Neurofibrillary tangles of Guam parkinson-dementia are associated with reactive microglia and complement proteins
    • DOI 10.1016/0006-8993(95)01257-5
    • Schwab C., Steele J. C. and McGeer P. L. (1996) Neurofibrillary tangles of Guam parkinson-dementia are associated with reactive microglia and complement proteins. Brain Res. 707, 196-205. (Pubitemid 26057584)
    • (1996) Brain Research , vol.707 , Issue.2 , pp. 196-205
    • Schwab, C.1    Steele, J.C.2    McGeer, P.L.3
  • 43
    • 55249083008 scopus 로고    scopus 로고
    • 3+ binds to BiP/GRP78 and induces unfolded protein response in HepG2 cells
    • 3+ binds to BiP/GRP78 and induces unfolded protein response in HepG2 cells. Chem. Biol. Interact. 176, 196-203.
    • (2008) Chem. Biol. Interact. , vol.176 , pp. 196-203
    • Shen, C.1    Li, Z.2    Yang, X.3    Wang, K.4
  • 44
    • 34247348628 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced apoptosis requires bax for commitment and Apaf-1 for execution in primary neurons
    • DOI 10.1038/sj.cdd.4402089, PII 4402089
    • Smith M. I. and Deshmukh M. (2007) Endoplasmic reticulum stress-induced apoptosis requires bax for commitment and Apaf-1 for execution in primary neurons. Cell Death Differ. 14, 1011-1019. (Pubitemid 46629839)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.5 , pp. 1011-1019
    • Smith, M.I.1    Deshmukh, M.2
  • 45
    • 1842854719 scopus 로고    scopus 로고
    • Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP
    • DOI 10.1038/sj.cdd.4401365
    • Tajiri S., Oyadomari S., Yano S., Morioka M., Gotoh T., Hamada J. I., Ushio Y. and Mori M. (2004) Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP. Cell Death Differ. 11, 403-415. (Pubitemid 38489418)
    • (2004) Cell Death and Differentiation , vol.11 , Issue.4 , pp. 403-415
    • Tajiri, S.1    Oyadomari, S.2    Yano, S.3    Morioka, M.4    Gotoh, T.5    Hamada, J.-I.6    Ushio, Y.7    Mori, M.8
  • 46
    • 9744243587 scopus 로고    scopus 로고
    • Mitochondrial viability and apoptosis induced by aluminum, mercuric mercury and methylmercury in cell lines of neural origin
    • Toimela T. and Tähti H. (2004) Mitochondrial viability and apoptosis induced by aluminum, mercuric mercury and methylmercury in cell lines of neural origin. Arch. Toxicol. 78, 565-574.
    • (2004) Arch. Toxicol. , vol.78 , pp. 565-574
    • Toimela, T.1    Tähti, H.2
  • 47
    • 0035155633 scopus 로고    scopus 로고
    • Acute and subacute physiological and histological studies of the central nervous system after intrathecal gadolinium injection in the anesthetized rat
    • Toney G. M., Chavez H. A. and Ibarra R. (2001) Acute and subacute physiological and histological studies of the central nervous system after intrathecal gadolinium injection in the anesthetized rat. Invest. Radiol. 36, 33-40.
    • (2001) Invest. Radiol. , vol.36 , pp. 33-40
    • Toney, G.M.1    Chavez, H.A.2    Ibarra, R.3
  • 48
    • 78049452644 scopus 로고    scopus 로고
    • Brainderived neurotrophic factor protects neurons from GdCl3-induced impairment in neuron-astrocyte co-cultures
    • Xia Q., Feng X. D., Yuan L., Yang X. D. and Wang K. (2010) Brainderived neurotrophic factor protects neurons from GdCl3-induced impairment in neuron-astrocyte co-cultures. Sci. China Chem. 53, 2193-2199.
    • (2010) Sci. China Chem. , vol.53 , pp. 2193-2199
    • Xia, Q.1    Feng, X.D.2    Yuan, L.3    Yang, X.D.4    Wang, K.5
  • 49
    • 4043048649 scopus 로고    scopus 로고
    • Opposed regulation of aluminum-induced apoptosis by glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor in rat brains
    • Yang S. J., Lee J. E., Lee K. H., Huh J. W., Choi S. Y. and Cho S. W. (2004) Opposed regulation of aluminum-induced apoptosis by glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor in rat brains. Mol. Brain Res. 127, 146-149.
    • (2004) Mol. Brain Res. , vol.127 , pp. 146-149
    • Yang, S.J.1    Lee, J.E.2    Lee, K.H.3    Huh, J.W.4    Choi, S.Y.5    Cho, S.W.6
  • 50
    • 33748126686 scopus 로고    scopus 로고
    • 3+in drinking water on gene expression in brains of rats
    • 3+ in drinking water on gene expression in brains of rats. J. Rare Earths 24, 369-373.
    • (2006) J. Rare Earths , vol.24 , pp. 369-373
    • Yang, W.1    Zhang, P.2    Liu, J.3    Xue, Y.4
  • 51
    • 0035966269 scopus 로고    scopus 로고
    • XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
    • DOI 10.1016/S0092-8674(01)00611-0
    • Yoshida H., Matsui T., Yamamoto A., Okada T. and Mori K. (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107, 881-891. (Pubitemid 34084979)
    • (2001) Cell , vol.107 , Issue.7 , pp. 881-891
    • Yoshida, H.1    Matsui, T.2    Yamamoto, A.3    Okada, T.4    Mori, K.5
  • 52
    • 0033015485 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: Suppression of oxidative stress and stabilization of calcium homeostasis
    • Yu Z., Luo H., Fu W. and Mattson M. P. (1999) The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp. Neurol. 155, 302-314.
    • (1999) Exp. Neurol. , vol.155 , pp. 302-314
    • Yu, Z.1    Luo, H.2    Fu, W.3    Mattson, M.P.4
  • 53
    • 33748857226 scopus 로고    scopus 로고
    • 3+-induced extracellular signal-regulated kinase (ERK) signaling via a metal-sensing mechanism linking proliferation and apoptosis in NIH 3T3 cells
    • DOI 10.1021/bi060895d
    • Yu S., Hu J., Yang X., Wang K. and Qian Z. M. (2006) La3+-induced extracellular signal-regulated kinase (ERK) signaling via a metalsensing mechanism linking proliferation and apoptosis in NIH 3T3 cells. Biochemistry 45, 11217-11225. (Pubitemid 44418955)
    • (2006) Biochemistry , vol.45 , Issue.37 , pp. 11217-11225
    • Yu, S.1    Hu, J.2    Yang, X.3    Wang, K.4    Qian, Z.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.