Augmentation of adenovirus 5 vector-mediated gene transduction under physiological pH conditions by a chitosan/NaHCO3 solution

Gene Therapy

Volumn 18, Issue 3, 2011, Pages 232-239

  Zhong, H ^a   Lei, X ^a   Qin, L ^a   Wang, J ^a   Hung, T ^a  

^a INSTITUTE OF PATHOGEN BIOLOGY   (China)

Author keywords

cationic polymer; chitosan; NaHCO3; recombinant adenovirus vector

Indexed keywords

ADENOVIRUS VECTOR; BICARBONATE; BOVINE SERUM ALBUMIN; CHITOSAN; COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR;

ANIMAL CELL; ARTICLE; CELL LINE; CHINESE HAMSTER; CONTROLLED STUDY; FEMALE; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MELANOMA B16; MOUSE; NONHUMAN; OVARY CELL; PH; PRIORITY JOURNAL; RAT; SOLUBILITY; TUMOR CELL; TUMOR XENOGRAFT; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; CELL LINE, TUMOR; CHITOSAN; CHO CELLS; CRICETINAE; CRICETULUS; GALACTOSIDES; GENETIC VECTORS; HYDROGEN-ION CONCENTRATION; INDOLES; MICE; MICE, INBRED C57BL; SODIUM BICARBONATE; SOLUBILITY; TOXICITY TESTS; TRANSDUCTION, GENETIC;

ADENOVIRIDAE; BOVINAE; CRICETULUS GRISEUS; HUMAN ADENOVIRUS TYPE 5; MURINAE; MUS;

EID: 79952487063     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2010.129     Document Type: Article

References (49)

1. Shirakawa T. Clinical trial design for adenoviral gene therapy products. Drug News Perspect 2009; 22: 140-145.
2. Shirakawa T. The current status of adenovirus-based cancer gene therapy. Mol Cells 2008; 25: 462-466.
3. Bergelson JM, Cunningham JA, Droguett G, Kurt-Jones EA, Krithivas A, Hong JS et al. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science 1997; 275: 1320-1323. (Pubitemid 27114163)
4. Anders M, Vieth M, Röcken C, Ebert M, Pross M, Gretschel S et al. Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression. Br J Cancer 2009; 100: 352-359.
5. O'Prey J, Wilkinson S, Ryan KM. Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapy. J Virol 2008; 82: 5933-5939. (Pubitemid 351822266)
6. Hochstein N, Webb D, Hösel M, Seidel W, Auerochs S, Doerfler W. Human CAR gene expression in nonpermissive hamster cells boosts entry of type 12 adenovirions and nuclear import of viral DNA. J Virol 2008; 82: 4159-4163. (Pubitemid 351521251)
7. Sebestyen Z, de Vrij J, Magnusson M, Debets R, Willemsen R. An oncolytic adenovirus redirected with a tumor-specific T-cell receptor. Cancer Res 2007; 67: 11309-11316. (Pubitemid 350248557)
8. Qian W, Liu J, Tong Y, Yan S, Yang C, Yang M et al. Enhanced antitumor activity by a selective conditionally replicating adenovirus combining with MDA-7/interleukin-24 for B-lymphoblastic leukemia via induction of apoptosis. Leukemia 2008; 22: 361-369. (Pubitemid 351250541)
9. Guse K, Ranki T, Ala-Opas M, Bono P, Särkioja M, Rajecki M et al. Treatment of metastatic renal cancer with capsid-modified oncolytic adenoviruses. Mol Cancer Ther 2007; 6: 2728-2736.
10. Wohlfahrt ME, Beard BC, Lieber A, Kiem HP. A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL Leads to enhanced cancer cell killing in human glioblastoma models. Cancer Res 2007; 67: 8783-8790. (Pubitemid 47437454)
11. Singh R, Tian B, Kostarelos K. Artificial envelopment of nonenveloped viruses: enhancing adenovirus tumor targeting in vivo. FA S E B J 2008; 22: 3389-3402.
12. Bonsted A, Engesaeter BØ, Høgset A, Maelandsmo GM, Prasmickaite L, Kaalhus O et al. Transgene expression is increased by photochemically mediated transduction of polycation-complexed adenoviruses. Gene Ther 2004; 11: 152-160. (Pubitemid 38159687)
13. Price AR, Limberis MP, Wilson JM, Diamond SL. Pulmonary delivery of adenovirus vector formulated with dexamethasone-spermine facilitates homologous vector re-administration. Gene Ther 2007; 14: 1594-1604. (Pubitemid 350056231)
14. Soenen SJ, Brisson AR, De Cuyper M. Addressing the problem of cationic lipid-mediated toxicity: the magnetoliposome model. Biomaterials 2009; 30: 3691-3701.
15. Moghimi SM, Symonds P, Murray JC, Hunter AC, Debska G, Szewczyk A. A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy. Mol Ther 2005; 11: 990-995. (Pubitemid 40724119)
16. Croyle MA, Cheng X, Sandhu A, Wilson JM. Development of novel formulations that enhance adenoviral-mediated gene expression in the lung in vitro and in vivo. Mol Ther 2001; 4: 22-28. (Pubitemid 32684698)
17. Kawamata Y, Nagayama Y, Nakao K, Mizuguchi H, Hayakawa T, Sato T et al. Receptor-independent augmentation of adenovirus-mediated gene transfer with chitosan in vitro. Biomaterials 2002; 23: 4573-4579. (Pubitemid 36151609)
18. Romoren K, Pedersen S, Smistad G, Evensen O, Thu BJ. The influence of formulation variables on in vitro transfection efficiency and physicochemical properties of chitosan-based polyplexes. Int J Pharm 2003; 261: 115-127. (Pubitemid 36962750)
19. Köping-Höggaird M, Vairum KM, Issa M, Danielsen S, Christensen BE, Stokke BT et al. Improved chitosan mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers. Gene Ther 2004; 11: 1441-1452.
20. Richardson SC, Kolbe HV, Duncan R. Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA. Int J Pharm 1999; 178: 231-243. (Pubitemid 29078577)
21. Rao SB, Sharma CP. Use of chitosan as a biomaterial: studies on its safety and hemostatic potential. J Biomed Mater Res 1997; 34: 21-28. (Pubitemid 26425214)
22. Morimoto M, Saimoto H, Usui H, Okamoto Y, Minami S, Shigemasa Y. Biological activities of carbohydrate-branched chitosan derivatives. Biomacromolecules 2001; 2: 1133-1136. (Pubitemid 34026889)
23. Kean T, Roth S, Thanou M. Trimethylated chitosans as non-viral gene delivery vectors: cytotoxicity and transfection efficiency. J Control Rel 2005; 103: 643-653. (Pubitemid 40471022)
24. Germershaus O, Mao SR, Sitterberg J, Bakowsky U, Kissel T. Gene delivery using chitosan, trimethyl chitosan, or polyethylenglycolgraft- trimethyl chitosan block copo-lymers: establishment of structure activity relationships in vitro. J Control Rel 2008; 125: 145-154. (Pubitemid 350299611)
25. Thanou M, Florea BI, Geldof M, Junginger HE, Borchard G. Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines. Biomaterials 2002; 23: 153-159. (Pubitemid 33041349)
26. Jiang X, Dai H, Leong KW, Goh SH, Mao HQ, Yang YY. Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions. J Gene Med 2006; 8: 477-487.
27. Zhang YQ, Chen JJ, Zhang YD, Pan YF, Zhao JF, Ren LF et al. A novel PEGylation of chitosan nanoparticles for gene delivery. Biotechnol Appl Biochem 2007; 46: 197-204.
28. Merdan T, Kunath K, Petersen H, Bakowsky U, Voigt KH, Kopecek J et al. PEGylation of poly(ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice. Biocon-jugate Chem 2005; 16: 785-792. (Pubitemid 41026164)
29. Mishra S, Webster P, Davis ME. PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles. Eur J Cell Biol 2004; 83: 97-111. (Pubitemid 38765217)
30. Strand SP, Issa MM, Christensen BE, Vairum KM, Artursson P. Tailoring of chitosans for gene delivery: novel self-branched glycosylated chitosan oligomers with improved functional properties. Biomacromolecules 2008; 9: 3268-3276.
31. Mizuguchi H, Hayakawa T. Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase. Cancer Gene Ther 2002; 9: 236-242. (Pubitemid 34205497)
32. Loré K, Adams WC, Havenga MJ, Precopio ML, Holterman L, Goudsmit J et al. Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses. J Immunol 2007; 179: 1721-1729.
33. Reagan KJ, Goldberg B, Crowell RL. Altered receptor specificity of coxsackievirus B3 after growth in rhabdomyosarcoma cells. J Virol 1984; 49: 635-640. (Pubitemid 14191119)
34. Niu G, Xiong Z, Cheng Z, Cai W, Gambhir SS, Xing L et al. In vivo bioluminescence tumor imaging of RGD peptide-modified adenoviral vector encoding firefly luciferase reporter gene. Mol Imaging Biol 2007; 9: 126-134. (Pubitemid 46705706)
35. Wu JC, Sundaresan G, Iyer M, Gambhir SS. Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice. Mol Ther 2001; 4: 297-306. (Pubitemid 33040513)
36. Alemany R. Cancer selective adenoviruses. Mol Aspects Med 2007; 28: 42-58.
37. Lee TW, Matthews DA, Blair GE. Novel molecular approaches to cystic fibrosis gene therapy. Biochem J 2005; 387 (Part 1): 1-15. (Pubitemid 40524069)
38. Descamps D, Benihoud K. Two key challenges for effective adenovirus-mediated liver gene therapy: innate immune responses and hepatocyte-specific transduction. Curr Gene Ther 2009; 9: 115-127.
39. Smits EL, Anguille S, Cools N, Berneman ZN, Van Tendeloo VF. Dendritic cell-based cancer gene therapy. Hum Gene Ther 2009; 20: 1106-1118.
40. Muzzarelli C, Tosi G, Francescangeli O, Muzzarelli RA. Alkaline chitosan solutions. Carbohydr Res 2003; 338: 2247-2255. (Pubitemid 38352690)
41. Senel S, McClure SJ. Potential applications of chitosan in veterinary medicine. Adv Drug Deliv Rev 2004; 56: 1467-1480. (Pubitemid 38748827)
42. Kuge H, Ohashi K, Yokoyama T, Kanehiro H, Hisanaga M, Koyama F et al. Genetic modification of hepatocytes towards hepatocyte transplantation and liver tissue engineering. Cell Transplant 2006; 15: 1-12.
43. Di Nicola M, Carlo-Stella C, Milanesi M, Magni M, Longoni P, Mortarini R et al. Large-scale feasibility of gene transduction into human CD34+ cell-derived dendritic cells by adenoviral/polycation complex. Br J Haematol 2000; 111: 344-350.
44. Bourbeau D, Lavoie G, Nalbantoglu J, Massie B. Suicide gene therapy with an adenovirus expressing the fusion gene CD::UPRT in human glioblastomas: different sensitivities correlate with p53 status. J Gene Med 2004; 6: 1320-1332. (Pubitemid 40287704)
45. Teramoto S, Ito H, Ouchi Y. Variables affecting the transduction efficiency of adenovirus vectors in bovine aortic endothelial cells. Thromb Res 1999; 93: 35-42. (Pubitemid 29012757)
46. Xiang YZ, Feng ZH, Zhang J, Liao YL, Yu CJ, Yi WJ et al. Linear cyclen-based polyamine as a novel and efficient reagent in gene delivery. Org Biomol Chem 2010; 8: 640-647.
47. Germershaus O, Merdan T, Bakowsky U, Behe M, Kissel T. Trastuzumab- polyethyle-nimine-polyethylene glycol conjugates for targeting Her2-expressing tumors. Bioconjug Chem 2006; 17: 1190-1199. (Pubitemid 44455327)
48. Miyake S, Makimura M, Kanegae Y, Harada S, Sato Y, Takamori K et al. Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc Natl Acad Sci USA 1996; 93: 1320-1324.
49. Yao H, Ng SS, Tucker WO, Tsang YK, Man K, Wang XM et al. The gene transfection efficiency of a folate-PEI600-cyclodextrin nanopolymer. Biomaterials 2009; 30: 5793-5803.