Discovery and synthesis of novel 3-phenylcoumarin derivatives as antidepressant agents

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 7, 2011, Pages 1937-1941

  Sashidhara, Koneni V ^a   Kumar, Abdhesh ^a   Chatterjee, Manavi ^a   Rao, K Bhaskara ^a   Singh, Seema ^a   Verma, Anil Kumar ^a   Palit, Gautam ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Antidepressant activity; Coumarin; Forced swim test; Synthesis; Tail suspension test

Indexed keywords

3 PHENYLCOUMARIN DERIVATIVE; ANTIDEPRESSANT AGENT; FLUOXETINE; IMIPRAMINE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ARTICLE; DRUG ACTIVITY; DRUG EFFICACY; DRUG MEGADOSE; DRUG POTENCY; DRUG PURITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FORCED SWIMMING TEST; LOW DRUG DOSE; NONHUMAN; ROTAROD TEST; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIDEPRESSIVE AGENTS; COUMARINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; MALE; MICE; SPECTROPHOTOMETRY, INFRARED; STRESS, PHYSIOLOGICAL; SWIMMING;

ANIMALIA; MUS;

EID: 79952484119     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.02.040     Document Type: Article

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