Automated sample preparation for regulated bioanalysis: An integrated multiple assay extraction platform using robotic liquid handling

Bioanalysis

Volumn 2, Issue 6, 2010, Pages 1023-1040

  Tweed, Joseph A ^a   Gu, Zhenhua ^a   Xu, Hui ^a   Zhang, Guodong ^a   Nouri, Parya ^a   Li, Ming ^a   Steenwyk, Rick ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EDETIC ACID; DRUG; PROTEIN;

ACCURACY; ANALYTIC METHOD; ARTICLE; AUTOANALYSIS; BIOASSAY; COMPUTER INTERFACE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTERMETHOD COMPARISON; LABORATORY AUTOMATION; LIMIT OF QUANTITATION; LIQUID LIQUID EXTRACTION; ONLINE ANALYSIS; PRECIPITATION; PROCESS DESIGN; QUALITY CONTROL; REPRODUCIBILITY; ROBOTICS; SOLID PHASE EXTRACTION; VALIDATION PROCESS; ANALYSIS; AUTOMATION; CHEMISTRY; COMPUTER GRAPHICS; DRUG DEVELOPMENT; FRACTIONATION; INSTRUMENTATION; ISOLATION AND PURIFICATION; METHODOLOGY; SYSTEM ANALYSIS;

ANALYTIC SAMPLE PREPARATION METHODS; AUTOMATION; CHEMICAL FRACTIONATION; CHEMICAL PRECIPITATION; COMPUTER GRAPHICS; DRUG DISCOVERY; HUMANS; PHARMACEUTICAL PREPARATIONS; PROTEINS; ROBOTICS; SOLID PHASE EXTRACTION; SYSTEMS INTEGRATION; USER-COMPUTER INTERFACE;

EID: 79952457129     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.10.55     Document Type: Article

References (41)

1. Hempenius J, Wieling J, Jonkman JH et al. Development of a laboratory robotic system for automated bioanalytical methods. I. The determination of theophylline in human plasma: a comparison between the robotized and manual method. J. Pharm. Biomed. Anal. 8(4), 313-320 (1990). (Pubitemid 20308918)
2. Allanson JP, Biddlecombe RA, Jones AE, Pleasance S. The use of automated solid phase extraction in the '96 well' format for high throughput bioanalysis using liquid chromatography coupled to tandem mass spectrometry. Rapid Commun. Mass Spectrom. 10(7), 811-816 (1996). (Pubitemid 126680248)
3. Kaye B, Herron WJ, Macrae PV et al. Rapid, solid phase extraction technique for the high-throughput assay of darifenacin in human plasma. Anal. Chem. 68(9), 1658-1660 (1996).
4. Janiszewski J, Schneider RP, Hoffmaster K et al. Automated sample-preparation using membrane microtiter extraction for bioanalytical mass spectrometry. Rapid Commun. Mass Spectrom. 11(9), 1033-1037 (1997). (Pubitemid 27269539)
5. Callejas SL, Biddlecombe RA, Jones AE et al. Determination of the glucocorticoid fluticasone propionate in plasma by automated solid-phase extraction and liquid chromatography-tandem mass spectrometry. J. Chromatogr. B 718(2), 243-250 (1998). (Pubitemid 28499998)
6. Joyce KB, Jones AE, Scott RJ, Biddlecombe RA, Pleasance S. Determination of the enantiomers of salbutamol and its 4-O-sulphate metabolites in biological matrices by chiral liquid chromatography tandem mass spectrometry. Rapid Commun. Mass Spectrom. 12(23), 1899-1910 (1998). (Pubitemid 28548083)
7. Simpson H, Berthemy A, Buhrman D et al. High-throughput liquid chromatography- mass spectrometry bioanalysis using 96-well disk solid-phase extraction plate for the sample-preparation. Rapid Commun. Mass Spectrom. 12(2), 75-82 (1998). (Pubitemid 28050423)
8. Chang MS, Ji Q, Zhang J, El-Shourbagy TA. Historical review of sample-preparation for chromatographic bioanalysis: pros and cons. Drug Dev. Res. 68(3), 107-133 (2007). (Pubitemid 47502822)
9. Jemal M, Teitz D, Ouyang Z, Khan S. Comparison of plasma sample purification by manual liquid-liquid extraction, automated 96-well liquid-liquid extraction and automated 96-well solid-phase extraction for analysis by high-performance liquid chromatography with tandem mass spectrometry. J. Chromatogr. B 732(2), 501-508 (1999). (Pubitemid 29460867)
10. Zhang N, Hoffman KL, Li W, Rossi DT. Semi-automated 96-well liquid-liquid extraction for quantitation of drugs in biological fluids. J. Pharm. Biomed. Anal. 22(1), 131-138 (2000). (Pubitemid 30089239)
11. Brignol N, McMahon LM, Luo S, Tse FLS. High-throughput semi-automated 96-well liquid-liquid extraction and liquid chromatography/mass spectrometric analysis of everolimus (RAD 001) and cyclosporin A (CsA) in whole blood. Rapid Commun. Mass Spectrom. 15(12), 898-907 (2001). (Pubitemid 32587177)
12. Peng SX, Branch TM, King SL. Fully automated 96-well liquid-liquid extraction for analysis of biological samples by liquid chromatography with tandem mass spectrometry. Anal. Chem. 73(3), 708-714 (2001).
13. Bolden RD, Hoke Ii SH, Eichhold TH, McCauley-Myers DL, Wehmeyer KR. Semi-automated liquid-liquid back-extraction in a 96-well format to decrease sample-preparation time for the determination of dextromethorphan and dextrorphan in human plasma. J. Chromatogr. B 772(1), 1-10 (2002). (Pubitemid 34450747)
14. Zhang N, Yang A, Rogers JD, Zhao JJ. Quantitative analysis of simvastatin and its -hydroxy acid in human plasma using automated liquid-liquid extraction based on 96-well plate format and liquid chromatography-tandem mass spectrometry. J. Pharm. Biomed. Anal. 34(1), 175-187 (2004). (Pubitemid 38114780)
15. Dotsikas Y, Kousoulos C, Tsatsou G, Loukas YL. Development and validation of a rapid 96-well format based liquid-liquid extraction and liquid chromatography- tandem mass spectrometry analysis method for ondansetron in human plasma. J. Chromatogr. B 836(1-2), 79-82 (2006).
16. Rodila RC, Kim JC, Ji QC, El-Shourbagy TA. A high-throughput, fully automated liquid/liquid extraction liquid chromatography/mass spectrometry method for the quantitation of a new investigational drug ABT-869 and its metabolite A-849529 in human plasma samples. Rapid Commun. Mass Spectrom. 20(20), 3067-3075 (2006). (Pubitemid 44569786)
17. Wang PG, Jun Z, Eric MG et al. A high-throughput liquid chromatography/tandem mass spectrometry method for simultaneous quantification of a hydrophobic drug candidate and its hydrophilic metabolite in human urine with a fully automated liquid/liquid extraction. Rapid Commun. Mass Spectrom. 20(22), 3456-3464 (2006). (Pubitemid 44763946)
18. Wang PG, Wei JS, Kim G, Chang M, El-Shourbagy T. Validation and application of a high-performance liquid chromatography-tandem mass spectrometric method for simultaneous quantification of lopinavir and ritonavir in human plasma using semi-automated 96-well liquid-liquid extraction. J. Chromatogr. A 1130(2), 302-307 (2006). (Pubitemid 44441317)
19. Zhang J, Reimer MT, Nicholas EA, Qin CJ, Tawakol AE-S. Method development and validation for zotarolimus concentration determination in stented swine arteries by liquid chromatography/ tandem mass spectrometry detection. Rapid Commun. Mass Spectrom. 20(22), 3427-3434 (2006). (Pubitemid 44763943)
20. Eichhold TH, McCauley-Myers DL, Khambe DA, Thompson GA, Hoke SH. Simultaneous determination of dextromethorphan, dextrorphan, and guaifenesin in human plasma using semi-automated liquid/liquid extraction and gradient liquid chromatography tandem mass spectrometry. J. Pharm. Biomed. Anal. 43(2), 586-600 (2007). (Pubitemid 44960549)
21. Antonian L, DeMontigny P, Wislocki PG. An automated method for the determination of subnanogram concentrations of eprinomectin in bovine plasma. J. Pharm. Biomed. Anal. 16(8), 1363-1371 (1998). (Pubitemid 28191791)
22. Kronkvist K, Gustavsson M, Wendel AK, Jaegfeldt H. Automated sample-preparation for the determination of budesonide in plasma samples by liquid chromatography and tandem mass spectrometry. J. Chromatogr. A 823(1-2), 401-409 (1998). (Pubitemid 28463506)
23. Zhang H, Henion J. Quantitative and qualitative determination of estrogen sulfates in human urine by liquid chromatography/tandem mass spectrometry using 96-well technology. Anal. Chem. 71(18), 3955-3964 (1999).
24. McMahon LM, Luo S, Hayes M, Tse FLS. High throughput analysis of everolimus (RAD001) and cyclosporin A (CsA) in whole blood by liquid chromatography/mass spectrometry using a semi-automated 96-well solid-phase extraction system. Rapid Commun. Mass Spectrom. 14(21), 1965-1971 (2000).
25. Rossi DT, Zhang N. Automating solid-phase extraction: current aspecs and future prospekts. J. Chromatogr. A 885(1-2), 97-113 (2000). (Pubitemid 30392473)
26. Biddlecombe RA, Benevides C, Pleasance S. A clinical trial on a plate? The potential of 384-well format solid phase extraction for high throughput bioanalysis using liquid chromatography tandem mass spectrometry. Rapid Commun. Mass Spectrom. 15(1), 33-40 (2001). (Pubitemid 32094789)
27. Matthews CZ, Woolf EJ, Lin L et al. High-throughput, semi-automated determination of a cyclooxygenase II inhibitor in human plasma and urine using solid-phase extraction in the 96-well format and high-performance liquid chromatography with post-column photochemical derivatization-fluorescence detection. J. Chromatogr. B 751(2), 237-246 (2001). (Pubitemid 32126311)
28. Rule G, Chapple M, Henion J. A 384-well solid-phase extraction for LC/MS/MS determination of methotrexate and its 7-hydroxy metabolite in human urine and plasma. Anal. Chem. 73(3), 439-443 (2001).
29. Shou WZ, Jiang X, Beato BD, Naidong W. A highly automated 96-well solid phase extraction and liquid chromatography/tandem mass spectrometry method for the determination of fentanyl in human plasma. Rapid Commun. Mass Spectrom. 15(7), 466-476 (2001). (Pubitemid 32294642)
30. Naidong W, Shou WZ, Addison T, Maleki S, Jiang X. Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE. Rapid Commun. Mass Spectrom. 16(20), 1965-1975 (2002).
31. Shou WZ, Pelzer M, Addison T, Jiang X, Naidong W. An automatic 96-well solid phase extraction and liquid chromatography-tandem mass spectrometry method for the analysis of morphine, morphine-3-glucuronide and morphine-6- glucuronide in human plasma. J. Pharm. Biomed. Anal. 27(1-2), 143-152 (2002). (Pubitemid 33001391)
32. Yang L, Clement RP, Kantesaria B et al. Validation of a sensitive and automated 96-well solid-phase extraction liquid chromatography-tandem mass spectrometry method for the determination of desloratadine and 3-hydroxydesloratadine in human plasma. J. Chromatogr. B 792(2), 229-240 (2003). (Pubitemid 36830873)
33. Tong XS, Wang J, Zheng S, Pivnichny JV. High-throughput pharmacokinetics screen of VLA-4 antagonists by LC/MS/MS coupled with automated solid-phase extraction sample-preparation. J. Pharm. Biomed. Anal. 35(4), 867-877 (2004). (Pubitemid 38757677)
34. Song Q, Junga H, Tang Y et al. Automated 96-well solid phase extraction and hydrophilic interaction liquid chromatography-tandem mass spectrometric method for the analysis of cetirizine (ZYRTEC®) in human plasma - with emphasis on method ruggedness. J. Chromatogr. B 814(1), 105-114 (2005). (Pubitemid 40017942)
35. Xue YJ, Akinsanya JB, Jane L, Steve EU. A simplified protein precipitation/mixed-mode cation-exchange solid-phase extraction, followed by high-speed liquid chromatography/mass spectrometry, for the determination of a basic drug in human plasma. Rapid Commun. Mass Spectrom. 20(18), 2660-2668 (2006). (Pubitemid 44497393)
36. Ma J, Shi J, Le H et al. A fully automated plasma protein precipitation sample-preparation method for LC-MS/MS bioanalysis. J. Chromatogr. B 862(1-2), 219-226 (2008).
37. Xue YJ, Liu J, Pursley J, Unger S. A 96-well single-pot protein precipitation, liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of muraglitazar, a novel diabetes drug, in human plasma. J. Chromatogr. B 831(1-2), 213-222 (2006). (Pubitemid 43155798)
38. Palandra J, Weller D, Hudson G et al. Flexible automated approach for quantitative liquid-handling of complex biological samples. Anal. Chem. 79(21), 8010-8015 (2007). (Pubitemid 350059995)
39. Xu RN, Fan L, Rieser MJ, El-Shourbagy TA. Recent advances in high-throughput quantitative bioanalysis by LC-MS/MS. J. Pharm. Biomed. Anal. 44(2), 342-355 (2007). (Pubitemid 46880094)
40. Xu S, Zheng S, Shen X et al. Automated sample-preparation and purification of homogenized brain tissues. J. Pharm. Biomed. Anal. 44(2), 581-585 (2007). (Pubitemid 46880098)
41. Deng Y, Wu JT, Lloyd TL et al. High-speed gradient parallel liquid chromatography/tandem mass spectrometry with fully automated sample-preparation for bioanalysis: 30 seconds per sample from plasma. Rapid Commun. Mass Spectrom. 16(11), 1116-1123 (2002). (Pubitemid 34555915)