5-Nitro-2-furoic acid hydrazones: Design, synthesis and in vitro antimycobacterial evaluation against log and starved phase cultures

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 15, 2010, Pages 4313-4316

  Sriram, Dharmarajan ^a   Yogeeswari, Perumal ^a   Vyas, Devambatla Ravi Kumar ^a   Senthilkumar, Palaniappan ^a   Bhat, Pritesh ^a   Srividya, Madala ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

5 Nitrofuranyl derivatives; Antitubercular activity; Dormant tuberculosis; Mycobacterium tuberculosis

Indexed keywords

5 NITRO 2 FUROIC ACID; 5 NITRO N'[(5 NITRO 2 FURYL)METHYLIDENE] 2 FUROHYDRAZIDE; ANTIMYCOBACTERIAL AGENT; HYDRAZONE DERIVATIVE; ISOCITRATE LYASE; N'[1 (4 BROMOPHENYL)ETHYLIDENE] 5 NITRO 2 FUROHYDRAZIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIUM CULTURE; CYTOTOXICITY TEST; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; GROWTH INHIBITION; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CERCOPITHECUS AETHIOPS; COMPUTER SIMULATION; DRUG DESIGN; ENZYME INHIBITORS; FURANS; HYDRAZINES; HYDRAZONES; ISOCITRATE LYASE; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM; VERO CELLS;

MYCOBACTERIUM TUBERCULOSIS;

EID: 77955415635     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.06.096     Document Type: Article

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