Determination and characterization of new benzimidazoles with activity against Trypanosoma cruzi by UV spectroscopy and HPLC

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 16, 2008, Pages 7622-7630

  Brain Isasi, Stephanie ^a   Quezada, Cristián ^a   Pessoa, Hernán ^a   Morello, Antonio ^b   Kogan, Marcelo J ^a   Álvarez Lueje, Alejandro ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

Antichagasic; Determination; HPLC; log P; Nitrophenylbenzimidazole; pKa; UV

Indexed keywords

1 (4 CHLOROBENZOYL) 2 (2 NITROPHENYL)BENZIMIDAZOLE; 1 (4 METHOXYBENZOYL) 2 (2 NITROPHENYL)BENZIMIDAZOLE; 1 (4 NITROBENZOYL) 2 (2 NITROPHENYL)BENZIMIDAZOLE; 1 BENZOYL 2 (2 NITROPHENYL)BENZIMIDAZOLE; 2 (2 NITROPHENYL)BENZIMIDAZOLE; BENZIMIDAZOLE DERIVATIVE; NIFURTIMOX; NITROBENZIMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG INHIBITION; EPIMASTIGOTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; LIPOPHILICITY; NONHUMAN; OXYGEN CONSUMPTION; POTENTIOMETRY; REPRODUCIBILITY; TRYPANOSOMA CRUZI; ULTRAVIOLET SPECTROSCOPY;

ANIMALS; BENZIMIDAZOLES; ELECTROCHEMISTRY; KINETICS; SPECTROPHOTOMETRY, ULTRAVIOLET; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 49149102278     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.07.021     Document Type: Article

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