Involvement of Rac GTPase activation in phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to ICAM-1

Biochemical and Biophysical Research Communications

Volumn 406, Issue 2, 2011, Pages 273-277

  Asai, Akira ^a   Okajima, Fumitaka ^a   Nakajima, Yasushi ^a   Nagao, Mototsugu ^a   Nakagawa, Kiyotaka ^b   Miyazawa, Teruo ^b   Oikawa, Shinichi ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Actin; Cell adhesion; Monocyte; Phosphatidylcholine hydroperoxide; Phospholipid oxidation; Rac

Indexed keywords

ACTIN; CHOLINE DERIVATIVE; CLOSTRIDIUM DIFFICILE TOXIN B; F ACTIN; FLUINDOSTATIN; GERANYLGERANYLTRANSFERASE; INTERCELLULAR ADHESION MOLECULE 1; ISOPRENOID; PHOSPHATIDYLCHOLINE HYDROPEROXIDE; PHOSPHOLIPID; RAC1 PROTEIN; RAC2 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSFERASE; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ARTICLE; CELL ADHESION; CELL MEMBRANE; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIPID OXIDATION; MOLECULAR MECHANICS; PRIORITY JOURNAL; RNA INTERFERENCE;

ACTINS; ALKYL AND ARYL TRANSFERASES; CELL ADHESION; CELL LINE; ENZYME ACTIVATION; FATTY ACIDS, MONOUNSATURATED; HUMANS; INDOLES; INTERCELLULAR ADHESION MOLECULE-1; LEUCINE; PHOSPHATIDYLCHOLINES; PROTEIN PRENYLATION; RAC GTP-BINDING PROTEINS; RNA INTERFERENCE;

CLOSTRIDIUM DIFFICILE;

EID: 79952450625     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.032     Document Type: Article

References (39)

1. Bochkov V.N., Oskolkova O.V., Birukov K.G., Levonen A.L., Binder C.J., Stökl J. Generation and biological activities of oxidized phospholipids. Antioxid. Redox Signal. 2010, 12:1009-1059.
2. Berliner J.A., Leitinger N., Tsimikas S. The role of oxidized phospholipids in atherosclerosis. J. Lipid Res. 2009, 50(Suppl.):S207-S212.
3. Fruhwirth G.O., Loidl A., Hermetter A. Oxidized phospholipids: from molecular properties to disease. Biochim. Biophys. Acta 2007, 1772:718-736.
4. Piotrowski J.J., Shah S., Alexander J.J. Mature human atherosclerotic plaque contains peroxidized phosphatidylcholine as a major lipid peroxide. Life Sci. 1996, 58:735-740.
5. Ravandi A., Babaei S., Leung R., Monge J.C., Hoppe G., Hoff H., Kamido H., Kuksis A. Phospholipids and oxophospholipids in atherosclerotic plaques at different stages of plaque development. Lipids 2004, 39:97-109.
6. Tokita Y., Hirayama Y., Sekikawa A., Kotake H., Toyota T., Miyazawa T., Sawai T., Oikawa S. Fructose ingestion enhances atherosclerosis and deposition of advanced glycated end-products in cholesterol-fed rabbits. J. Atheroscler. Thromb. 2005, 12:260-267.
7. Kinoshita M., Oikawa S., Hayasaka K., Sekikawa A., Nagashima T., Toyota T., Miyazawa T. Age-related increases in plasma phosphatidylcholine hydroperoxide concentrations in control subjects and patients with hyperlipidemia. Clin. Chem. 2000, 46:822-828.
8. Chien C.T., Chang W.T., Chen H.W., Wang T.D., Liou S.Y., Chen T.J., Chang Y.L., Lee Y.T., Hsu S.M. Ascorbate supplement reduces oxidative stress in dyslipidemic patients undergoing apheresis. Arterioscler. Thromb. Vasc. Biol. 2004, 24:1111-1117.
9. Nagashima T., Oikawa S., Hirayama Y., Tokita Y., Sekikawa A., Ishigaki Y., Yamada R., Miyazawa T. Increase of serum phosphatidylcholine hydroperoxide dependent on glycemic control in type 2 diabetic patients. Diabetes Res. Clin. Pract. 2002, 56:19-25.
10. Adachi J., Matsushita S., Yoshioka N., Funae R., Fujita T., Higuchi S., Ueno Y. Plasma phosphatidylcholine hydroperoxide as a new marker of oxidative stress in alcoholic patients. J. Lipid Res. 2004, 45:967-971.
11. Beckman J.A., Creager M.A., Libby P. Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA 2002, 287:2570-2581.
12. Hurst R.T., Lee R.W. Increased incidence of coronary atherosclerosis in type 2 diabetes mellitus: mechanisms and management. Ann. Intern. Med. 2003, 139:824-834.
13. Steinberg D. An interpretive history of the cholesterol controversy, part III: mechanistically defining the role of hyperlipidemia. J. Lipid Res. 2005, 46:2037-2051.
14. Asai A., Okajima F., Nakagawa K., Ibusuki D., Tanimura K., Nakajima Y., Nagao M., Sudo M., Harada T., Miyazawa T., Oikawa S. Phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to intracellular adhesion molecule-1. J. Lipid Res. 2009, 50:957-965.
15. Øterud B., Bjøklid E. Role of monocytes in atherogenesis. Physiol. Rev. 2003, 83:1069-1112.
16. Ibusuki D., Nakagawa K., Asai A., Oikawa S., Masuda Y., Suzuki T., Miyazawa T. Preparation of pure lipid hydroperoxides. J. Lipid Res. 2008, 49:2668-2677.
17. Hui S.P., Chiba H., Sakurai T., Asakawa C., Nagasaka H., Murai T., Ide H., Kurosawa T. An improved HPLC assay for phosphatidylcholine hydroperoxides (PCOOH) in human plasma with synthetic PCOOH as internal standard. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2007, 857:158-163.
18. Jaffe A.B., Hall A. Rho GTPases: biochemistry and biology. Annu. Rev. Cell Dev. Biol. 2005, 21:247-269.
19. Takai Y., Sasaki T., Matozaki T. Small GTP-binding proteins. Physiol. Rev. 2001, 81:153-208.
20. Wennerberg K., Der C.J. Rho-family GTPases: it's not only Rac and Rho (and I like it). J. Cell Sci. 2004, 117:1301-1312.
21. Didsbury J., Weber R.F., Bokoch G.M., Evans T., Snyderman R. Rac, a novel ras-related family of proteins that are botulinum toxin substrates. J. Biol. Chem. 1989, 264:16378-16382.
22. Guo F., Cancelas J.A., Hildeman D., Williams D.A., Zheng Y. Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development. Blood 2008, 112:1767-1775.
23. Sun C.X., Magalhãs M.A., Glogauer M. Rac1 and Rac2 differentially regulate actin free barbed end formation downstream of the fMLP receptor. J. Cell Biol. 2007, 179:239-245.
24. Kalfa T.A., Pushkaran S., Mohandas N., Hartwig J.H., Fowler V.M., Johnson J.F., Joiner C.H., Williams D.A., Zheng Y. Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton. Blood 2006, 108:3637-3645.
25. Wheeler A.P., Wells C.M., Smith S.D., Vega F.M., Henderson R.B., Tybulewicz V.L., Ridley A.J. Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. J. Cell Sci. 2006, 119:2749-2757.
26. Hoppe A.D., Swanson J.A. Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis. Mol. Biol. Cell 2004, 15:3509-3519.
27. Sun C.X., Downey G.P., Zhu F., Koh A.L., Thang H., Glogauer M. Rac1 is the small GTPase responsible for regulating the neutrophil chemotaxis compass. Blood 2004, 104:3758-3765.
28. Gu Y., Filippi M.D., Cancelas J.A., Siefring J.E., Williams E.P., Jasti A.C., Harris C.E., Lee A.W., Prabhakar R., Atkinson S.J., Kwiatkowski D.J., Williams D.A. Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Science 2003, 302:445-449.
29. Rosenfeldt H., Castellone M.D., Randazzo P.A., Gutkind J.S. Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk. J. Mol. Signal. 2006, 1:8.
30. Wozniak M.A., Kwong L., Chodniewicz D., Klemke R.L., Keely P.J. R-Ras controls membrane protrusion and cell migration through the spatial regulation of Rac and Rho. Mol. Biol. Cell 2005, 16:84-96.
31. Nimnual A.S., Taylor L.J., Bar-Sagi D. Redox-dependent downregulation of Rho by Rac. Nat. Cell Biol. 2003, 5:236-241.
32. Li Z., Aizenman C.D., Cline H.T. Regulation of rho GTPases by crosstalk and neuronal activity in vivo. Neuron 2002, 33:741-750.
33. Cox E.A., Sastry S.K., Huttenlocher A. Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases. Mol. Biol. Cell 2001, 12:265-277.
34. Zondag G.C., Evers E.E., ten Klooster J.P., Janssen L., van der Kammen R.A., Collard J.G. Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition. J. Cell Biol. 2000, 149:775-782.
35. Sander E.E., ten Klooster J.P., van Delft S., van der Kammen R.A., Collard J.G. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J. Cell Biol. 1999, 147:1009-1022.
36. Rottner K., Hall A., Small J.V. Interplay between Rac and Rho in the control of substrate contact dynamics. Curr. Biol. 1999, 9:640-648.
37. Wang Z., Thurmond D.C. Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins. J. Cell Sci. 2009, 122:893-903.
38. Papakonstanti E.A., Stournaras C. Cell responses regulated by early reorganization of actin cytoskeleton. FEBS Lett. 2008, 582:2120-2127.
39. Etienne-Manneville S., Hall A. Rho GTPases in cell biology. Nature 2002, 420:629-635.