GABAergic disinhibition induced pain hypersensitivity by upregulating NMDA receptor functions in spinal dorsal horn

Neuropharmacology

Volumn 60, Issue 6, 2011, Pages 921-929

  Cao, Jing ^a   Yang, Xian ^a   Liu, Yan Ni ^a   Suo, Zhan Wei ^a   Shi, Lei ^a   Zheng, Cheng Rong ^a   Yang, Hong Bin ^a   Li, Shuai ^a   Hu, Xiao Dong ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

Benzodiazepines; cAMP dependent protein kinase; GABAA receptor; Inflammatory pain; NMDA receptor

Indexed keywords

4 AMINOBUTYRIC ACID; BICUCULLINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIAZEPAM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; SERINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; GABAERGIC SYSTEM; HYPERALGESIA; INFLAMMATION; LOW DRUG DOSE; MALE; MOUSE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SPINAL CORD DORSAL HORN; SYNAPTIC TRANSMISSION; UPREGULATION;

2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; BICUCULLINE; DIAZEPAM; DRUG INTERACTIONS; EXCITATORY AMINO ACID ANTAGONISTS; GABA-A RECEPTOR ANTAGONISTS; HYPERALGESIA; ISOQUINOLINES; MALE; MICE; MICE, INBRED C57BL; NEURAL INHIBITION; PHOSPHORYLATION; POSTERIOR HORN CELLS; PROTEIN KINASE INHIBITORS; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE; SULFONAMIDES;

EID: 79952449552     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.01.034     Document Type: Article

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