A continuous membrane microbioreactor system for development of integrated pectin modification and separation processes

Chemical Engineering Journal

Volumn 167, Issue 2-3, 2011, Pages 418-426

  Alam, Muhd Nazrul Hisham Zainal ^a,b   Pinelo, Manuel ^a   Samanta, Kama ^a   Jonsson, Gunnar ^a   Meyer, Anne ^a   Gernaey, Krist V ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b UNIVERSITI TEKNOLOGI MALAYSIA   (Malaysia)

Author keywords

Continuous; Membrane separation; Microbioreactor; Pectin hydrolysis; Scale down

Indexed keywords

CONTINUOUS; MEMBRANE SEPARATION; MICROBIOREACTOR; PECTIN HYDROLYSIS; SCALE DOWN;

BIOPOLYMERS; BIOREACTORS; DEGRADATION; ENZYMES; HYDROLYSIS; REACTOR OPERATION;

MEMBRANES;

EID: 79952449009     PISSN: 13858947     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cej.2010.09.082     Document Type: Article

References (30)

1. Rosgaard L., Pedersen S., Cherry J.R., Harris P., Meyer A.S. Efficiency of new fungal cellulase systems in boosting enzymatic degradation of barley straw lignocellulose. Biotechnology Progress 2006, 22:493-498.
2. Sørensen H.R., Pedersen S., Meyer A.S. Synergistic enzyme mechanisms and effects of sequential enzyme additions on degradation of water insoluble wheat arabinoxylan. Enzyme Microbial Technology 2007, 40:908-918.
3. Arnous A., Meyer A.S. Discriminated release of phenolic substances from red wine grape skins (Vitis vinifera L.) by multicomponent enzymes treatment. Biochemical Engineering 2010, 49:68-77.
4. Lye G.J., Ayazi-Shamlou P., Baganz F., Dalby P.A., Woodley J.M. Accelerated design of bioconversion processes using automated microscale processing techniques. Trends in Biotechnology 2003, 21(1):29-37.
5. Rachinskiy K., Schultze H., Boy M., BornScheuer U., Buchs J. Enzyme test bench' a high-throughput enzyme characterization technique including the long-term stability. Biotechnology and Bioengineering 2009, 103(2):305-322.
6. Pinelo M., Jonsson G., Meyer A.S. Membrane technology for purification of enzymatically produced oligosaccharides: molecular and operational features affecting performance. Separation and Purification Technology 2009, 70:1-11.
7. Schäpper D., Zainal Alam M.N.H., Szita N., Lantz A.E., Gernaey K.V. Application of microbioreactors in fermentation process development: a review. Analytical and Bioanalytical Chemistry 2009, 395(3):679-695.
8. Zhang Z., Boccazzi P., Choi H., Perozziello G., Sinskey A.J., Jensen K.F. Microchemostat-microbial continuous culture in a polymer-based instrumented microbioreactor. Lab on a Chip 2006, 6:906-913.
9. Swarts J.W., Vossenberg P., Meerman M.H., Janssen A.E.M., Boom R.M. Comparison of two-phase lipase-catalyzed esterification on micro and bench scale. Biotechnology and Bioengineering 2008, 99(4):855-861.
10. Muller D.H., Liauw M.A., Greiner L. Microreaction technology in education: miniaturized enzyme membrane reactor. Chemical Engineering Technology 2005, 28(12):1569-1571.
11. de Jong J., Lammertink R.G.H., Wessling M. Membranes and microfluidics: a review. Lab on a Chip 2006, 6:1125-1139.
12. Miyazaki M., Maeda H. Microchannel enzyme reactors and their applications for processing. Trends in Biotechnology 2006, 24(10):463-470.
13. Urban P.L., Goodall D.M., Bruce N.C. Enzyme microreactors in chemical analysis and kinetic studies. Biotechnology Advances 2006, 24:42-57.
14. Pijanowska D.G., Baraniecka A., Wiater R., Ginalska G., Lobarzewski J., Torbicz W. The pH-detection of triglycerides. Sensors and Actuators B 2001, 78:263-266.
15. Gao J., Xu J., Locasscio L.E., Lee C.S. Integrated microfluidics system enabling protein digestion, peptide separation, and protein identification. Analytical Chemistry 2001, 73(11):2648-2655.
16. Diano N., Grimaldi T., Bianco M., Rossi S., Gabrovska K., Yordanova G., Godjevargova T., Grano V., Nicolucci C., Mita L., Bencivenga U., Canciglia P., Mita D.G. Apple juice clarification by immobilized pectolytic enzymes in packed or fluidized bed reactors. Agricultural, Food and Chemistry 2008, 56:11471-11477.
17. Kee S., Gavriilidis A. Design and performance of a microstructured PEEK reactor for continuous poly-l-leucine-catalysed chalcone epoxidation. Organic Process Research and Development 2009, 13:941-951.
18. Znidarsic-Plazl P., Plazl I. Modelling and experimental studies on lipase-catalysed isoamyl acetated synthesis in a microreactor. Process Biochemistry 2009, 44:1115-1121.
19. Li X., van der Steen G., van Dedem G.W.K., Van der Wielen L.A.M., Van Leeuwen M., Van Gulik W.M., Heijnen J.J., Krommenhoek E.E., Gardeniers J.G.E., van den Berg A., Ottens M. Improving mixing in microbioreactors. Chemical Engineering Science 2008, 63:3036-3046.
20. Nikolic M.V., Mojovic L. Hydrolysis of apple pectin by coordinated activity of pectic enzymes. Food Chemistry 2007, 101:1-9.
21. Zainal Alam M.N.H., Schäpper D., Gernaey K.V. Embedded resistance wire as heating element for temperature control in microbioreactors. Journal of Micromechanics and Microengineering 2010, 20:055014. 10.1088/0960-1317/20/5/055014.
22. Yadav S., Yadav P.K., Yadav D., Yadav K.D.S. Pectin lyase: a review. Process Biochemistry 2009, 44:1-10.
23. van den Broek L.A.M., den Aantrekker E.D., Voragen A.G.J., Beldman G., Vincken J.P. Pectin lyase is a key enzyme in the maceration of potato tuber. Science of Food and Agriculture 1997, 75:167-172.
24. Ryu K.S., Shaikh K., Goluch E., Fan Z., Liu C. Micro magnetic stir-bar mixer integrated with paralene microfluidics channels. Lab on a Chip 2004, 4:608-613.
25. Gallifuoco A., Alfani F., Cantarella M., Viparelli P. New experimental procedure for monitoring molecular weight breakdown during enzymatic degradation of polygalacturonic acid in continuous membrane reactors. Industrial and Engineering Chemistry Research 2003, 42:3937-3942.
26. I.C.R. Silva, Characterization of Aspergillus enzymes for pectin modification, MSc Thesis, Center for BioProcess Engineering, Department of Chemical and Biochemical Engineering, Technical University of Denmark (DTU), 2008.
27. Rodriguez-Nogales J.M., Ortega N., Perez-Mateos M., Busto M.D. Pectin hydrolysis in a free enzyme membrane reactor: an approach to the wine and juice clarification. Food Chemistry 2008, 107:112-119.
28. Delattre C., Michaud P., Vijayalakshmi M.A. New monolithic enzymatic micro-reactor for the fast production and purification of oligogalacturonides. Chromatography 2008, 861:203-208.
29. Mannheim A., Cheryan M. Continuous hydrolysis of milk protein in a membrane reactor. Food Science 1990, 55:381-385.
30. Jonsson G. Selectivity in membrane filtration. Synthetic Membranes: Science, Engineering and Applications 2004, Springer. J.K. Bungay, P.M. Bungay, H.K. Lonslade, M.N. Pinho (Eds.).