Targeting PI3K/Akt/HSP90 signaling sensitizes gastric cancer cells to deoxycholate-induced apoptosis

Digestive Diseases and Sciences

Volumn 56, Issue 2, 2011, Pages 323-329

  Redlak, Maria J ^a   Miller, Thomas A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AGS cell line; Apoptosis; Cell signaling; Heat shock proteins

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; CASPASE 9; DEOXYCHOLIC ACID; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SMALL INTERFERING RNA; WORTMANNIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL STRUCTURE; CELL SURVIVAL; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME DEGRADATION; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; REGULATORY MECHANISM; RNA INTERFERENCE; SENSITIZATION; SIGNAL TRANSDUCTION; STOMACH CANCER; STOMACH EPITHELIUM; WESTERN BLOTTING;

ANDROSTADIENES; APOPTOSIS; BENZOQUINONES; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CHROMONES; DEOXYCHOLIC ACID; DRUG DELIVERY SYSTEMS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

EID: 79952440468     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-010-1294-2     Document Type: Article

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