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Volumn 41, Issue 2, 2010, Pages 73-88

Progress on phytochemical and atopic dermatitis-related study of the root of Lithospermum erythrorhizon

Author keywords

Antiinflammatory; Atopic dermatitis; Lithosperminic acid; Lithospermum erythrorhizon; Shikonin

Indexed keywords

LITHOSPERMUM ERYTHRORHIZON EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

EID: 79952379868     PISSN: 02533073     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (11)

References (88)
  • 1
    • 0033213309 scopus 로고    scopus 로고
    • Propionylshikonin from the roots of Lithospermum erythrorhizon cultivated in Korea
    • Cho, M. H., Paik, Y. S. and Hahn, T. R. (1999) Propionylshikonin from the roots of Lithospermum erythrorhizon cultivated in Korea. J. Agric. Food. Chem. 47: 4117-4120.
    • (1999) J. Agric. Food. Chem. , vol.47 , pp. 4117-4120
    • Cho, M.H.1    Paik, Y.S.2    Hahn, T.R.3
  • 2
    • 79952386169 scopus 로고    scopus 로고
    • Korean source
  • 3
    • 79952400284 scopus 로고    scopus 로고
    • Korean source
  • 4
    • 0033213309 scopus 로고    scopus 로고
    • Physical stability of shikonin derivatives from the roots of Lithospermm erythrorhizon cultivated in Korea
    • Cho, M. H., Paik, Y. S. and Hahn, T. R. (1999) Physical stability of shikonin derivatives from the roots of Lithospermm erythrorhizon cultivated in Korea. J. Agric. Food Chem. 47: 4117-4120.
    • (1999) J. Agric. Food Chem. , vol.47 , pp. 4117-4120
    • Cho, M.H.1    Paik, Y.S.2    Hahn, T.R.3
  • 5
    • 79952428968 scopus 로고    scopus 로고
    • Korean source
  • 8
    • 79952406477 scopus 로고    scopus 로고
    • Shikonin, an active principle of the medicinal plant Lithospermm erythrorhizon, is a potent scavenger of peroxyradicals in cigarette smoke
    • Niwano, Y., Nishizawa, M. and Kohno, M. (2007) Shikonin, an active principle of the medicinal plant Lithospermm erythrorhizon, is a potent scavenger of peroxyradicals in cigarette smoke. Recent Progress in Medicinal Plants 18: 201-214.
    • (2007) Recent Progress in Medicinal Plants , vol.18 , pp. 201-214
    • Niwano, Y.1    Nishizawa, M.2    Kohno, M.3
  • 9
    • 0034192471 scopus 로고    scopus 로고
    • Antioxidant properties of components extracted from puccoon (Lithospermum erythrorhizon Sieb. et Zucc.)
    • DOI 10.1016/S0308-8146(99)00236-8, PII S0308814699002368
    • Weng, X. C., Xiang, G. Q., Jiang, A. L., Liu, Y. P., Wu, L. L., Dong, X. W. and Duan, S. (2000) Antioxidant properties of components extracted from puccoon (Lithospermm erythrorhizon Sieb. et Zucc.). Food Chemistry 69: 143-146. (Pubitemid 30162919)
    • (2000) Food Chemistry , vol.69 , Issue.2 , pp. 143-146
    • Weng, X.C.1    Xiang, G.Q.2    Jiang, A.L.3    Liu, Y.P.4    Wu, L.L.5    Dong, X.W.6    Duan, S.7
  • 10
    • 0029117713 scopus 로고
    • Inhibition of platelet activation by shikonin derivatives isolated from Arnebia euchroma
    • Ko, F. N., Lee, Y. S., Chang, Y. S. and Teng, C. M. (1995) Inhibition of platelet activation by shikonin derivatives isolated from Arnebia euchroma. Biochim. Biophys. Acta 1268: 329-334.
    • (1995) Biochim. Biophys. Acta , vol.1268 , pp. 329-334
    • Ko, F.N.1    Lee, Y.S.2    Chang, Y.S.3    Teng, C.M.4
  • 12
    • 0032796797 scopus 로고    scopus 로고
    • Shikonin, an ingredient of Lithospermum erythrorhizon induced apoptosis in HL60 human premyelocytic leukemia cell line
    • DOI 10.1055/s-1999-14010
    • Yoon, Y., Kim, Y.-O., Lim, N.-Y., Jeon, W.-K. and Sung, H. J. (1999) Shikonin, an ingredient of Lithospermm erythrorhizon induced apoptosis in HL60 human premyelocytic leukemia cell line. Planta Medica 65: 532-535. (Pubitemid 29399955)
    • (1999) Planta Medica , vol.65 , Issue.6 , pp. 532-535
    • Yoon, Y.1    Kim, Y.-O.2    Lim, N.-Y.3    Jeon, W.-K.4    Sung, H.J.5
  • 15
    • 69049111714 scopus 로고    scopus 로고
    • Shikonin, an ingredient of Lithospermm erythrorhizon, down-regulates the expression of steroid sulfatase genes in breast cancer cells
    • Zhang, Y., Qian, R.-Q. and Li, P.-Pi. (2009) Shikonin, an ingredient of Lithospermm erythrorhizon, down-regulates the expression of steroid sulfatase genes in breast cancer cells. Cancer Letters 284: 47-54.
    • (2009) Cancer Letters , vol.284 , pp. 47-54
    • Zhang, Y.1    Qian, R.-Q.2    Li, P.-Pi.3
  • 16
    • 79952404756 scopus 로고    scopus 로고
    • Korean source
  • 17
    • 79952427068 scopus 로고    scopus 로고
    • Korean source
  • 18
    • 79952415551 scopus 로고    scopus 로고
    • Korean source
  • 19
    • 0348031261 scopus 로고    scopus 로고
    • Efficacy and tolerability of borage oil in adults and children with atopic eczema: Randomised, double blind, placebo controlled, parallel group trial
    • Takwale, A., Tan, E.; Agarwal, S., Barclay, G., Ahmed, I., Hotchkiss, K., Thompson, J. R., Chapman, T. and Berth-Jones, J. (2003) Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. British Medical Journal 327: 1385-1387. (Pubitemid 37543949)
    • (2003) British Medical Journal , vol.327 , Issue.7428 , pp. 1385-1387
    • Takwale, A.1    Tan, E.2    Agarwal, S.3    Barclay, G.4    Ahmed, I.5    Hotchkiss, K.6    Thompson, J.R.7    Chapman, T.8    Berth-Jones, J.9
  • 20
    • 79952376354 scopus 로고    scopus 로고
    • Korean source
  • 21
    • 77958545948 scopus 로고    scopus 로고
    • Ecological characteristics of Lithospermum erythrorhizon population in habitat
    • Ahn, Y. H., Jin, Y. H., Choe, C. Y., Lee, K. M. and Lee, S. (2009) Ecological characteristics of Lithospermum erythrorhizon population in habitat, Korean Journal of Pharmacognosy 40: 289-297.
    • (2009) Korean Journal of Pharmacognosy , vol.40 , pp. 289-297
    • Ahn, Y.H.1    Jin, Y.H.2    Choe, C.Y.3    Lee, K.M.4    Lee, S.5
  • 23
    • 0035990608 scopus 로고    scopus 로고
    • Cellular pharmacology studies of shikonin derivatives
    • Chen, X., Yang, L., Oppenheim, J. J. and Howard, O. M. Z. (2002) Cellular pharmacology studies of shikonin derivatives. Phytother. Res. 16: 199-209.
    • (2002) Phytother. Res. , vol.16 , pp. 199-209
    • Chen, X.1    Yang, L.2    Oppenheim, J.J.3    Howard, O.M.Z.4
  • 24
    • 61549085024 scopus 로고    scopus 로고
    • Alkannins and Shikonins: A new class of wound healing agents
    • Papageorgiou, V. P., Assimopoulou, A. N. and Ballis, A. C. (2008) Alkannins and Shikonins: A new class of wound healing agents. Curr. Med. Chem. 15: 3248-3267.
    • (2008) Curr. Med. Chem. , vol.15 , pp. 3248-3267
    • Papageorgiou, V.P.1    Assimopoulou, A.N.2    Ballis, A.C.3
  • 25
    • 0345538947 scopus 로고
    • The coloring matter in Lithospermum erythrorhizone
    • Kuroda, C. (1918) The coloring matter in Lithospermum erythrorhizone. Tokyo Kagaku Kaishi 39: 1051-1115.
    • (1918) Tokyo Kagaku Kaishi , vol.39 , pp. 1051-1115
    • Kuroda, C.1
  • 26
    • 0343729848 scopus 로고
    • The coloring matter of Lithospermum erythrorhizon
    • Miamima, R. and Kuroda, C. (1922) The coloring matter of Lithospermum erythrorhizon. Acta Phytochimica 1: 43-65.
    • (1922) Acta Phytochimica , vol.1 , pp. 43-65
    • Miamima, R.1    Kuroda, C.2
  • 27
    • 84977689700 scopus 로고
    • Constitution of alkannin, shikonin and alkannan
    • Brockmann, H. (1935) Constitution of alkannin, shikonin and alkannan. Justus Liebigs Ann. Chem. 521: 1-47.
    • (1935) Justus Liebigs Ann. Chem. , vol.521 , pp. 1-47
    • Brockmann, H.1
  • 28
    • 0003009208 scopus 로고
    • Absolute configuration of shikonin and alkannin
    • Arakawa, H. and Nakazaki, M. (1961) Absolute configuration of shikonin and alkannin. Chem. Ind. (London) 947.
    • (1961) Chem. Ind. (London) , pp. 947
    • Arakawa, H.1    Nakazaki, M.2
  • 29
    • 0012266078 scopus 로고
    • Formation of stereoisomeric mixtures of naphthoquinone derivatives in Echium lycopsis callus cultures
    • Fukui, H., Tsukada, M., Mizukami, H. and Tabata, M. (1983) Formation of stereoisomeric mixtures of naphthoquinone derivatives in Echium lycopsis callus cultures. Phytochemistry 22: 453-456.
    • (1983) Phytochemistry , vol.22 , pp. 453-456
    • Fukui, H.1    Tsukada, M.2    Mizukami, H.3    Tabata, M.4
  • 30
    • 0021570489 scopus 로고
    • Analysis of naphthoquinone pigments in Chinese medicinal 'zicao'. Arnebia euchroma
    • Fu, S. L., Shang, T. M. and Xiao, P. G. (1984) Analysis of naphthoquinone pigments in Chinese medicinal 'zicao'. Arnebia euchroma. Yaoxue Xuebao 19: 921-920.
    • (1984) Yaoxue Xuebao , vol.19 , pp. 921-1920
    • Fu, S.L.1    Shang, T.M.2    Xiao, P.G.3
  • 31
    • 77957716955 scopus 로고    scopus 로고
    • Identification of shikonin and its derivatives for Lithospermum erythrorhizon
    • Kim, J.-s., Han, Y.-s. and Kang, M.-h. (2006) Identification of shikonin and its derivatives for Lithospermum erythrorhizon. J. Korean Soc Food Sci. Nutr. 35: 177-181.
    • (2006) J. Korean Soc Food Sci. Nutr. , vol.35 , pp. 177-181
    • Kim, J.-S.1    Han, Y.-S.2    Kang, M.-H.3
  • 32
    • 85046244032 scopus 로고
    • New naphthoquinone derivative from Lithospermm erythrorhizon
    • Morimoto, I. and Hirata, Y. (1965) New naphthoquinone derivative from Lithospermm erythrorhizon. Tetrahedron Lett. 7: 4737-4739.
    • (1965) Tetrahedron Lett. , vol.7 , pp. 4737-4739
    • Morimoto, I.1    Hirata, Y.2
  • 33
    • 0006989892 scopus 로고
    • Constituents of shikon. II. Comparison of contents, constituents, and antibacterial effect of fat soluble fraction between nanshikon and kosikon
    • Kyogoku, K., Terayama, H., Tachi, Y., Suzuki, T. and Komatsu, M. (1973) Constituents of shikon. II. Comparison of contents, constituents, and antibacterial effect of fat soluble fraction between nanshikon and kosikon. Shoyakugaku Zasshi 27: 24-30.
    • (1973) Shoyakugaku Zasshi , vol.27 , pp. 24-30
    • Kyogoku, K.1    Terayama, H.2    Tachi, Y.3    Suzuki, T.4    Komatsu, M.5
  • 34
    • 44349145027 scopus 로고    scopus 로고
    • Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones
    • Cui, X.-R., Tsukada, M., Suzuki, N., Shimamura, T., Gao, L., Koyanagi, J., Komada, F. and Saito, S. (2008) Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones. European J. Med. Chem. 43: 1206-1215.
    • (2008) European J. Med. Chem. , vol.43 , pp. 1206-1215
    • Cui, X.-R.1    Tsukada, M.2    Suzuki, N.3    Shimamura, T.4    Gao, L.5    Koyanagi, J.6    Komada, F.7    Saito, S.8
  • 35
    • 34548206402 scopus 로고    scopus 로고
    • Antioxidants from a Chinese medicinal herb. Lithospermm erythrorhizon
    • Han, J., Weng, X. and Bi, K. (2008) Antioxidants from a Chinese medicinal herb. Lithospermm erythrorhizon. Food Chemistry 106: 2-10.
    • (2008) Food Chemistry , vol.106 , pp. 2-10
    • Han, J.1    Weng, X.2    Bi, K.3
  • 36
    • 0001124861 scopus 로고
    • Studies on the shikon I. Structures of new minor pigments and isolation of two isomers of shikonin derivatives from Lithospermum erythrorhizon Sieb. et Zucc
    • Hisamichi, S. and Yoshizaki, F. (1982) Studies on the shikon I. Structures of new minor pigments and isolation of two isomers of shikonin derivatives from Lithospermum erythrorhizon Sieb. et Zucc. Shoyakugaku Zasshi 36: 154-159.
    • (1982) Shoyakugaku Zasshi , vol.36 , pp. 154-159
    • Hisamichi, S.1    Yoshizaki, F.2
  • 37
    • 0020459489 scopus 로고
    • Studies on shikon. III. New furylhydroquinone derivatives, shikonofurans A, B, C, D and E, from Lithospermum erythrorhizon Sieb. et Zucc
    • Yoshizaki, F., Hisamichi, S., Kondo, Y., Sato, Y. and Nozoe, S. (1982) Studies on shikon. III. New furylhydroquinone derivatives, shikonofurans A, B, C, D and E, from Lithospermum erythrorhizon Sieb. et Zucc. Chem. Pharm. Bull. 30: 4407-4411.
    • (1982) Chem. Pharm. Bull. , vol.30 , pp. 4407-4411
    • Yoshizaki, F.1    Hisamichi, S.2    Kondo, Y.3    Sato, Y.4    Nozoe, S.5
  • 38
    • 0036227108 scopus 로고    scopus 로고
    • Determination of naturally occurring hydroxynaphthoquinone polymers by size-exclusion chromatography
    • Papageorgiou, V. P., Assimopoulou, A. N. and Kyriacou, G. (2002) Determination of naturally occurring hydroxynaphthoquinone polymers by size-exclusion chromatography. Chromatographia 55: 423-430. (Pubitemid 34415791)
    • (2002) Chromatographia , vol.55 , Issue.7-8 , pp. 423-430
    • Papageorgiou, V.P.1    Assimopoulou, A.N.2    Kyriacou, G.3
  • 39
    • 65349167373 scopus 로고    scopus 로고
    • Preparative isolation and purification of alkannin/shikonin derivatives from natural products by high-speed counter-current chromatography
    • Assimopoulou, A. N., Sturm, S., Stuppner H. and Papageorgiou, V. P. (2009) Preparative isolation and purification of alkannin/shikonin derivatives from natural products by high-speed counter-current chromatography. Biomed. Chromatogr. 23: 182-198.
    • (2009) Biomed. Chromatogr. , vol.23 , pp. 182-198
    • Assimopoulou, A.N.1    Sturm, S.2    Stuppner, H.3    Papageorgiou, V.P.4
  • 40
    • 0001513503 scopus 로고
    • Two phenolic acids from Lithospermm erythrorhizon cell suspension cultures
    • Fukui, H., Yazaki, K. and Tabata, M. (1984) Two phenolic acids from Lithospermm erythrorhizon cell suspension cultures. Phytochemistry 23: 2398-2399.
    • (1984) Phytochemistry , vol.23 , pp. 2398-2399
    • Fukui, H.1    Yazaki, K.2    Tabata, M.3
  • 41
    • 0034620735 scopus 로고    scopus 로고
    • Caffeic acid oligomers in Lithospermum erythrorhizon cell suspension cultures
    • DOI 10.1016/S0031-9422(99)00623-8, PII S0031942299006238
    • Yamamoto, H., Inoue, K. and Yazaki, K. (2000) Caffeic acid oligomers in Lithospermum erythrorhizon cell suspension cultures. Phytochemistry 53: 651-657. (Pubitemid 30148783)
    • (2000) Phytochemistry , vol.53 , Issue.6 , pp. 651-657
    • Yamamoto, H.1    Inoue, K.2    Yazaki, K.3
  • 42
    • 0036690360 scopus 로고    scopus 로고
    • Regulation of lithospermic Acid B and shikonin production in Lithospermm erythrorhizon cell suspension cultures
    • Yamamoto, H., Zhao, P., Yazaki, K. and Inoue, K. (2002) Regulation of lithospermic Acid B and shikonin production in Lithospermm erythrorhizon cell suspension cultures. Chem. Pharm. Bull. 50: 1086-1090.
    • (2002) Chem. Pharm. Bull. , vol.50 , pp. 1086-1090
    • Yamamoto, H.1    Zhao, P.2    Yazaki, K.3    Inoue, K.4
  • 43
    • 84966142151 scopus 로고
    • Harvesting profitable products from plant tissue culture
    • Curtin, M. E. (1983) Harvesting profitable products from plant tissue culture. Biotechnology 1: 649-657.
    • (1983) Biotechnology , vol.1 , pp. 649-657
    • Curtin, M.E.1
  • 44
    • 0037023673 scopus 로고    scopus 로고
    • Enhancement of shikonin production in single- And two-phase suspension cultures of Lithospermum erythrorhizon cells using low-energy ultrasound
    • DOI 10.1002/bit.10180
    • Lin, L. and Wu, J. (2002) Enhancement of shikonin production in single- and two-phase suspension cultures of Lithospermm erythrorhizon cells using low-energy ultra-sound. Biotechnology and Bioengineering 78: 81-88. (Pubitemid 34712175)
    • (2002) Biotechnology and Bioengineering , vol.78 , Issue.1 , pp. 81-88
    • Lin, L.1    Wu, J.2
  • 45
    • 0032896184 scopus 로고    scopus 로고
    • Worldwide variations in the prevalence of symptoms of atopic eczema in the international study of asthma and allergies in childhood
    • Williams, H., Robertson, C., Stewart, A., Ait-Khaled, N., Anabwani, G. A., Anderson, R. et al. (1999) Worldwide variations in the prevalence of symptoms of atopic eczema in the international study of asthma and allergies in childhood. J. Allergy Clin. Immunol. 103: 125-138.
    • (1999) J. Allergy Clin. Immunol. , vol.103 , pp. 125-138
    • Williams, H.1    Robertson, C.2    Stewart, A.3    Ait-Khaled, N.4    Anabwani, G.A.5    Anderson, R.6
  • 46
    • 77952752109 scopus 로고    scopus 로고
    • Korean ISAAC Study Group of Korean Association of Allergy and Respiratory Diseases: Report of Korean ISAAC epidemiologic study for asthma and allergic diseases in children
    • Hong, S. J. (2007) Korean ISAAC Study Group of Korean Association of Allergy and Respiratory Diseases: Report of Korean ISAAC epidemiologic study for asthma and allergic diseases in children. Pediatr. Allergy Respir. Dis. (Korea) 17: Suppl 1: S55-66.
    • (2007) Pediatr. Allergy Respir. Dis. (Korea) , vol.17 , Issue.SUPPL. 1
    • Hong, S.J.1
  • 47
    • 0028087325 scopus 로고
    • Atopic dermatitis: Recent trends in pathogenesis and therapy
    • Cooper, K. D. (1994) Atopic dermatitis: recent trends in pathogenesis and therapy. J. Invest. Dermatol. 102: 128-37.
    • (1994) J. Invest. Dermatol. , vol.102 , pp. 128-137
    • Cooper, K.D.1
  • 48
    • 79952425645 scopus 로고    scopus 로고
    • Korean source
  • 49
    • 79952381757 scopus 로고    scopus 로고
    • Korean source
  • 50
    • 79952417640 scopus 로고    scopus 로고
    • Korean source
  • 51
    • 79952372887 scopus 로고    scopus 로고
    • Korean source
  • 52
    • 79952381384 scopus 로고    scopus 로고
    • Korean source
  • 53
    • 79952370572 scopus 로고    scopus 로고
    • Korean source
  • 55
    • 79952422076 scopus 로고    scopus 로고
    • Effects of Lithospermi radix on anti-CD40 and recombinant interleukin-A4-induced cytokine production in murine B-cells
    • Park, D. W., Lee, Y. S., Seo, Y. B., Ahn, D.-K., Seo, Y.-B. and Choi, H.-Y. (2003) Effects of Lithospermi radix on anti-CD40 and recombinant interleukin-A4-induced cytokine production in murine B-cells. The Korean Journal of Herbology 18: 73-81.
    • (2003) The Korean Journal of Herbology , vol.18 , pp. 73-81
    • Park, D.W.1    Lee, Y.S.2    Seo, Y.B.3    Ahn, D.-K.4    Seo, Y.-B.5    Choi, H.-Y.6
  • 56
    • 79952373241 scopus 로고    scopus 로고
    • Korean source
  • 59
    • 43249124764 scopus 로고    scopus 로고
    • Suppressive effects of Lithospermm erythrorhizon extracts on lipopolysaccharide-induced activation of AP-1 and NF-kappaB via mitogen-activated protein kinase pathways in mouse macrophage cells
    • Han, K. Y., Kwon, T. H., Lee, T. H., Lee, S. J., Kim, S. H. and Kim J. (2008) Suppressive effects of Lithospermm erythrorhizon extracts on lipopolysaccharide-induced activation of AP-1 and NF-kappaB via mitogen-activated protein kinase pathways in mouse macrophage cells. BMB Rep. 41: 328-333.
    • (2008) BMB Rep. , vol.41 , pp. 328-333
    • Han, K.Y.1    Kwon, T.H.2    Lee, T.H.3    Lee, S.J.4    Kim, S.H.5    Kim, J.6
  • 60
    • 34248233499 scopus 로고    scopus 로고
    • Protection of human keratinocytes from UVB-induced inflammation using root extract of Lithospermm erythrorhizon
    • Ishida, T. and Sakaguchi, I. (2007) Protection of human keratinocytes from UVB-induced inflammation using root extract of Lithospermm erythrorhizon. Biol. Pharm. Bull. 30: 928-934.
    • (2007) Biol. Pharm. Bull. , vol.30 , pp. 928-934
    • Ishida, T.1    Sakaguchi, I.2
  • 61
    • 50849096377 scopus 로고    scopus 로고
    • Shikonins attenuate microglial inflammatory responses by inhibition of ERK, Akt, and NF-κB: Neuroprotective implications
    • Nam, K. N., Son, M. S., Park, J. H. and Lee, E. H. (2008) Shikonins attenuate microglial inflammatory responses by inhibition of ERK, Akt, and NF-κB: neuroprotective implications. Neuropharmacology 55: 819-825.
    • (2008) Neuropharmacology , vol.55 , pp. 819-825
    • Nam, K.N.1    Son, M.S.2    Park, J.H.3    Lee, E.H.4
  • 62
    • 0035111811 scopus 로고    scopus 로고
    • Shikonin, a component of antiinflammatory Chinese herbal medicine, selectively blocks chemokine binding to CC chemokine receptor-1
    • Chen, X., Oppenheim, J. and Howard, O. M. (2001) Shikonin, a component of antiinflammatory Chinese herbal medicine, selectively blocks chemokine binding to CC chemokine receptor-1. Int. Immunopharmacol. 1: 229-236.
    • (2001) Int. Immunopharmacol. , vol.1 , pp. 229-236
    • Chen, X.1    Oppenheim, J.2    Howard, O.M.3
  • 64
    • 0034716986 scopus 로고    scopus 로고
    • D-Serine inhibits serine palmitoyltransferase, the enzyme catalyzing the initial step of sphingolipid biosynthesis
    • DOI 10.1016/S0014-5793(00)01579-9, PII S0014579300015799
    • Hanada, K., Hara, T. and Nishijima, M. (2000) D-Serine inhibits serine palmitoyltransferase, the enzyme catalyzing the initial step of sphingolipid biosynthesis. FEBS Letters 474: 63-65. (Pubitemid 30320833)
    • (2000) FEBS Letters , vol.474 , Issue.1 , pp. 63-65
    • Hanada, K.1    Hara, T.2    Nishijima, M.3
  • 65
    • 0033801107 scopus 로고    scopus 로고
    • Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier
    • Tanno, O., Ota, Y., Kitamura, N., Katsube, T. and Inoue, S., (2000) Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier. Br. J. Dermatol. 143: 524-531.
    • (2000) Br. J. Dermatol. , vol.143 , pp. 524-531
    • Tanno, O.1    Ota, Y.2    Kitamura, N.3    Katsube, T.4    Inoue, S.5
  • 66
    • 61449218775 scopus 로고    scopus 로고
    • Lithospermic acid derivatives from Lithospermm erythrorhizon increased expression of serine palmitoyltransferase in human HaCaT cells
    • Thuong, P. T., Kang, K. W., Kim, J. K,, Seo, D. B., Lee, S. J., Kim, S. H. and Oh, W. K. (2009) Lithospermic acid derivatives from Lithospermm erythrorhizon increased expression of serine palmitoyltransferase in human HaCaT cells. Bioorg. Med. Chem. Lett. 19: 1815-1817.
    • (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 1815-1817
    • Thuong, P.T.1    Kang, K.W.2    Kim, J.K.3    Seo, D.B.4    Lee, S.J.5    Kim, S.H.6    Oh, W.K.7
  • 67
    • 79952394900 scopus 로고    scopus 로고
    • Korean source
  • 68
    • 79952399903 scopus 로고    scopus 로고
    • Korean source
  • 71
    • 79952391319 scopus 로고    scopus 로고
    • Korean source
  • 72
    • 69749103899 scopus 로고    scopus 로고
    • Oral supplementation of Lithospermm erythrorhizon prevents the development of atopic dermatitis with reducing ceramide degradation in the epidermis of NC/Nga mice
    • Kim, J.-.M., Kim, Y.-R., Seo, D.-B., Kim, S.-H., Lee, S.-J. and Cho, Y. (2009) Oral supplementation of Lithospermm erythrorhizon prevents the development of atopic dermatitis with reducing ceramide degradation in the epidermis of NC/Nga mice. Phytother. Res. 23: 1250-1256.
    • (2009) Phytother. Res. , vol.23 , pp. 1250-1256
    • Kim, J.-M.1    Kim, Y.-R.2    Seo, D.-B.3    Kim, S.-H.4    Lee, S.-J.5    Cho, Y.6
  • 74
    • 33748987046 scopus 로고    scopus 로고
    • Comparative effect of gromwell (Lithospermm erythrorhizon) extract and borage oil on reversing epidermal hyperproliferation in guinea pigs
    • Kim, J., Kim, H., Jeong, D. H., Kim, S. H., Park, S. K. and Cho, Y. (2006) Comparative effect of gromwell (Lithospermm erythrorhizon) extract and borage oil on reversing epidermal hyperproliferation in guinea pigs. Biosci. Biotechnol. Biochem. 70: 2086-95.
    • (2006) Biosci. Biotechnol. Biochem. , vol.70 , pp. 2086-2095
    • Kim, J.1    Kim, H.2    Jeong, D.H.3    Kim, S.H.4    Park, S.K.5    Cho, Y.6
  • 75
    • 79952418043 scopus 로고    scopus 로고
    • Korean source
  • 76
    • 79952406476 scopus 로고    scopus 로고
    • Korean source
  • 77
    • 1242339613 scopus 로고    scopus 로고
    • Shikonins, phytocompounds from Lithospermm erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor alpha promoter in vivo
    • Staniforth, V., Wang, S. Y., Shyur, L. F. and Yang, N. S. (2004) Shikonins, phytocompounds from Lithospermm erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor alpha promoter in vivo. J. Biol. Chem. 279: 5877-5885.
    • (2004) J. Biol. Chem. , vol.279 , pp. 5877-5885
    • Staniforth, V.1    Wang, S.Y.2    Shyur, L.F.3    Yang, N.S.4
  • 78
    • 34347378942 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-alpha through selective blockade of Pre-mRNA splicing by shikonin
    • Chiu, S. C. and Yang, N. S. (2007) Inhibition of tumor necrosis factor-alpha through selective blockade of Pre-mRNA splicing by shikonin. Mol. Pharmacol. 71: 1640-1645.
    • (2007) Mol. Pharmacol. , vol.71 , pp. 1640-1645
    • Chiu, S.C.1    Yang, N.S.2
  • 80
    • 69249221221 scopus 로고    scopus 로고
    • Anti-inflammatory and barrier protecting effect of Lithospermm erythrorhizon extracts in chronic oxazolone-induced murine atopic dermatitis
    • Lee, J. H., Jung, K.-M., Bae, I.-H., Cho, S. Y., Seo, D.-B., Lee, S.-J., Park Y. H. and Lim, K.-M. (2009) Anti-inflammatory and barrier protecting effect of Lithospermm erythrorhizon extracts in chronic oxazolone-induced murine atopic dermatitis. Journal of Dermatological Science 256: 64-66.
    • (2009) Journal of Dermatological Science , vol.256 , pp. 64-66
    • Lee, J.H.1    Jung, K.-M.2    Bae, I.-H.3    Cho, S.Y.4    Seo, D.-B.5    Lee, S.-J.6    Park, Y.H.7    Lim, K.-M.8
  • 81
    • 84982560368 scopus 로고
    • Feeding trial with alkannin on mice
    • Majlathova, L. (1971) Feeding trial with alkannin on mice. Die Nahrung 15: 505-508
    • (1971) Die Nahrung , vol.15 , pp. 505-508
    • Majlathova, L.1
  • 82
    • 79952396619 scopus 로고
    • [Chem. Abstr. 1971, 76: 122 513].
    • (1971) Chem. Abstr. , vol.76
  • 83
    • 0017462605 scopus 로고
    • Pharmacological studies of shikon and tooki. (2) Pharmacological effects of the pigment components, shikonin and acetylshikonin
    • Hayashi, M. (1977) Pharmacological studies of shikon and tooki. (2) Pharmacological effects of the pigment components, shikonin and acetylshikonin. Nippon Yakurigaku Zasshi 73: 193-203
    • (1977) Nippon Yakurigaku Zasshi , vol.73 , pp. 193-203
    • Hayashi, M.1
  • 84
    • 85030284475 scopus 로고
    • [Chem. Abstr. 1977, 88: 44863e].
    • (1977) Chem. Abstr. , vol.88
  • 85
    • 0017460914 scopus 로고
    • Pharmaceutical studies on crude plant drugs, shikonin and tooki
    • Hayashi, M. (1977) Pharmaceutical studies on crude plant drugs, shikonin and tooki. Nippon Yakurigaku Zasshi 73: 177-191.
    • (1977) Nippon Yakurigaku Zasshi , vol.73 , pp. 177-191
    • Hayashi, M.1
  • 86
    • 79952415195 scopus 로고    scopus 로고
    • Determination of shikonin content in Arnebia euchroma extracts from four kinds of solvent systems and experimental observation on its acute toxicity
    • CAN 146: 344647
    • Dai, B., Zhou, X.-b., Yin, A.-w., Pan, Y.-s. and Zou, S.-h. (2005) Determination of shikonin content in Arnebia euchroma extracts from four kinds of solvent systems and experimental observation on its acute toxicity. Zhongguo Zhongyiyao Keji 12: 168-169, CAN 146: 344647.
    • (2005) Zhongguo Zhongyiyao Keji , vol.12 , pp. 168-169
    • Dai, B.1    Zhou, X.-B.2    Yin, A.-W.3    Pan, Y.-S.4    Zou, S.-H.5
  • 88
    • 79952424481 scopus 로고
    • [Chem. Abstr. 1988, 109: 47 792u].
    • (1988) Chem. Abstr. , vol.109


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