Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier

British Journal of Dermatology

Volumn 143, Issue 3, 2000, Pages 524-531

  Tanno, O ^a   Ota, Y ^a   Kitamura, N ^a   Katsube, T ^a   Inoue, S ^a  

^a KANEBO LTD   (Japan)

Author keywords

Ceramide synthesis; Epidermal permeability barrier; Nicotinamide; Serine palmitoyl transferase; Stratum corneum lipids

Indexed keywords

CERAMIDE; CHOLESTEROL; FATTY ACID; GLUCOSYLCERAMIDE; NICOTINAMIDE; SERINE; SKIN LIPID; SPHINGOLIPID; SPHINGOMYELIN; TRANSFERASE;

ARTICLE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; EPIDERMIS; FATTY ACID SYNTHESIS; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; KERATINOCYTE; LIPOGENESIS; NEWBORN; NORMAL HUMAN; PRIORITY JOURNAL; SKIN PERMEABILITY; STRATUM CORNEUM;

ACYLTRANSFERASES; BLOTTING, NORTHERN; CARBON RADIOISOTOPES; CELLS, CULTURED; CERAMIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMIS; HUMAN; INFANT, NEWBORN; KERATINOCYTES; MALE; NIACINAMIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN ABSORPTION; SPHINGOMYELINS; UP-REGULATION;

EID: 0033801107     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.2000.03705.x     Document Type: Article

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