Anti-inflammatory and barrier protecting effect of Lithospermum erythrorhizon extracts in chronic oxazolone-induced murine atopic dermatitis

Journal of Dermatological Science

Volumn 56, Issue 1, 2009, Pages 64-66

  Lee, Ji Hae ^a   Jung, Kyoung Mi ^a   Bae, Il Hong ^a   Cho, SiYoung ^a   Seo, Dae Bang ^a   Lee, Sang Jun ^a   Park, Young Ho ^a   Lim, Kyung Min ^a  

^a AmorePacific Corporation   (South Korea)

Author keywords

Atopic dermatitis; Lithospermum erythrorhizon; Oxazolone; Skin barrier

Indexed keywords

IMMUNOGLOBULIN E; LITHOSPERMUM ERYTHRORHIZON EXTRACT; OXAZOLONE; PLANT EXTRACT; PREDNISOLONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ATOPIC DERMATITIS; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; HISTOPATHOLOGY; IMMUNOGLOBULIN BLOOD LEVEL; LETTER; LITHOSPERMUM; LITHOSPERMUM ERYTHRORHIZON; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN PROTECTION; SKIN WATER LOSS;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHRONIC DISEASE; CYCLOOXYGENASE 2; DERMATITIS, ATOPIC; FEMALE; I-KAPPA B PROTEINS; LITHOSPERMUM; MICE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; OXAZOLONE; PHYTOTHERAPY; PLANT EXTRACTS; PREDNISOLONE; SKIN;

EID: 69249221221     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2009.07.001     Document Type: Letter

References (10)

1. Leung D.Y., Boguniewicz M., Howell M.D., Nomura I., and Hamid Q.A. New insights into atopic dermatitis. J Clin Invest 113 5 (2004) 651-657
2. Abramovits W., and Perlmutter A. Steroids versus other immune modulators in the management of allergic dermatoses. Curr Opin Allergy Clin Immunol 6 5 (2006) 345-354
3. Staniforth V., Wang S.Y., Shyur L.F., and Yang N.S. Shikonins, phytocompounds from Lithospermum erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor α promoter in vivo. J Biol Chem 279 7 (2004) 5877-5885
4. Thuong P.T., Kang K.W., Kim J.K., Seo D.B., Lee S.J., Kim S.H., et al. Lithospermic acid derivatives from Lithospermum erythrorhizon increased expression of serine palmitoyltransferase in human HaCaT cells. Bioorg Med Chem Lett 19 6 (2009) 1815-1817
5. Kim E.K., Kim E.Y., Moon P.D., Um J.Y., Kim H.M., Lee H.S., et al. Lithospermi radix extract inhibits histamine release and production of inflammatory cytokine in mast cells. Biosci Biotechnol Biochem 71 (2007) 2886-2892
6. Kim J., Kim H., Jeong do H., Kim S.H., Park S.K., and Cho Y. Comparative effect of gromwell (Lithospermum erythrorhizon) extract and borage oil on reversing epidermal hyperproliferation in guinea pigs. Biosci Biotechnol Biochem 70 9 (2006) 2086-2095
7. Man M.Q., Hatano Y., Lee S.H., Man M., Chang S., Feingold K.R., et al. Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges. J Invest Dermatol 128 (2008) 79-86
8. Han K.Y., Kwon T.H., Lee T.H., Lee S.J., Kim S.H., and Kim J. Suppressive effects of Lithospermum erythrorhizon extracts on lipopolysaccharide-induced activation of AP-1 and NF-kappaB via mitogen-activated protein kinase pathways in mouse macrophage cells. BMB Rep 41 4 (2008) 328-333
9. Lee K.M., Kang B.S., Lee H.L., Son S.J., Hwang S.H., Kim D.S., et al. Spinal NF-κB activation induces COX-2 upregulation and contributes to inflammatory pain hypersensitivity. Eur J Neurosci 19 12 (2004) 3375-3381
10. Lim K.M., Lee J.Y., Lee S.M., Bae O.N., Noh J.Y., Kim E.J., et al. Potent anti-inflammatory effects of two quinolinedione compounds, OQ1 and OQ21, mediated by dual inhibition of inducible NO synthase and cyclooxygenase-2. Br J Pharmacol 156 2 (2009) 328-337