Ret finger protein 2 enhances ionizing radiation-induced apoptosis via degradation of AKT and MDM2

European Journal of Cell Biology

Volumn 90, Issue 5, 2011, Pages 420-431

  Joo, Hae Mi ^a   Kim, Ji Young ^a   Jeong, Jae Boon ^a   Seong, Ki Moon ^a   Nam, Seon Young ^a   Yang, Kwang Hee ^a   Kim, Cha Soon ^a   Kim, Hee Sun ^a   Jeong, Meeseon ^a   An, Sungkwan ^b   Jin, Young Woo ^a  

^a Korea Hydro & Nuclear Power Co   (South Korea)

^b Konkuk University   (South Korea)

Author keywords

AKT; Apoptosis; E3 ubiquitin ligase; MDM2; P53; Ret finger protein 2 (RFP2); Ubiquitination

Indexed keywords

PROTEASOME; PROTEIN BAX; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P21; PROTEIN P53; PROTEIN RET; RET FINGER PROTEIN 2; RING FINGER PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STABILITY; RADIATION DOSE; UBIQUITINATION; WILD TYPE;

APOPTOSIS; DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MDM2; RADIATION, IONIZING; RECOMBINANT FUSION PROTEINS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 79952364124     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcb.2010.12.001     Document Type: Article

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