TRIM45, a novel human RBCC/TRIM protein, inhibits transcriptional activities of ElK-1 and AP-1

Biochemical and Biophysical Research Communications

Volumn 323, Issue 1, 2004, Pages 9-16

  Wang, Yuequn ^a   Li, Yongqing ^a   Qi, Xinzhu ^a   Yuan, Wuzhou ^a   Ai, Jianping ^a   Zhu, Chuanbing ^a   Cao, Lei ^a   Yang, Hong ^a   Liu, Fang ^a   Wu, Xiushan ^a   Liu, Mingyao ^a  

^a HUNAN NORMAL UNIVERSITY   (China)

Author keywords

Elk 1; MAPK signaling pathway; RBCC TRIM proteins; Transcription factor repressor; TRIM45

Indexed keywords

FILAMIN; IMMUNOGLOBULIN; PROTEIN; RING B BOX COILED COIL DOMAIN PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR ELK 1; TRIPARTITE MOTIF PROTEIN 45; UNCLASSIFIED DRUG; MITOGEN ACTIVATED PROTEIN KINASE;

ADULT; ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CELL STRAIN COS7; CELLULAR DISTRIBUTION; CYTOPLASM; DNA LIBRARY; EMBRYO; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN EMBRYO; HUMAN TISSUE; MOLECULAR WEIGHT; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN MOTIF; TRANSCRIPTION REGULATION; CONTROLLED STUDY; COS 7 CELL LINE; EXON; GENE OVEREXPRESSION; INTRON; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; PROTEIN STRUCTURE; RING FINGER MOTIF; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; BLOTTING, NORTHERN; CELL DIFFERENTIATION; CELL DIVISION; CELL NUCLEUS; CLONING, MOLECULAR; COMPUTATIONAL BIOLOGY; COS CELLS; CYTOPLASM; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; ETS-DOMAIN PROTEIN ELK-1; EXONS; GENE LIBRARY; GENES, REPORTER; HUMANS; MAP KINASE SIGNALING SYSTEM; MOLECULAR SEQUENCE DATA; MYOCARDIUM; OPEN READING FRAMES; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; RNA; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

CERVUS ELAPHUS;

EID: 4444301523     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.08.048     Document Type: Article

References (32)

1. A. Reymond, G. Meroni, A. Fantozzi, G. Merla, S. Cairo, and L. Luzi The tripartite motif family identifies cell compartments EMBO J. 20 2001 2140 2151
2. B.A. Reddy, L.D. Etkin, and P.S. Freemont A novel zinc finger coiled-coil domain in a family of nuclear proteins Trends Biochem. Sci. 17 1992 344 345
3. P.S. Freemont RING for destruction? Curr. Biol. 10 2000 R84 R87
4. K.L. Borden, J.M. Lally, S.R. Martin, N.J. O'Reilly, E. Solomon, and P.S. Freemont In vivo and in vitro characterization of the B1 and B2 zinc-binding domains from the acute promyelocytic leukemia protooncoprotein PML Proc. Natl. Acad. Sci. USA 93 1996 1601 1606
5. F.J. Slack, and G. Ruvkun A novel repeat domain that is often associated with RING finger and B-box motifs Trends Biochem. Sci. 23 1998 474 475
6. H. Peng, G.E. Begg, D.C. Schultz, J.R. Friedman, D.E. Jensen, D.W. Speicher, and F.J. Rauscher III Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B-Box-Coiled-coil domain-mediated protein-protein interactions J. Mol. Biol. 295 2000 1139 1162
7. X. Li, and L.D. Etkin Xenopus nuclear factor 7 (xnf7) possesses an NLS that functions efficiently in both oocytes and embryos J. Cell Sci. 105 1993 389 395
8. K.L. Borden RING fingers and B-boxes: zinc-binding protein-protein interaction domains Biochem. Cell Biol. 76 1998 351 358
9. E. Remboutsika, Y. Lutz, A. Gansmuller, J.L. Vonesch, R. Losson, and P. Chambon The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin J. Cell Sci. 112 1999 1671 1683
10. R.F. Ryan, D.C. Schultz, K. Ayyanathan, P.B. Singh, J.R. Friedman, W.J. Fredericks, and F.J. Rauscher III KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing Mol. Cell. Biol. 19 1999 4366 4378
11. K. Jensen, C. Shiels, and P.S. Freemont PML protein isoforms and the RBCC/TRIM motif Oncogene 20 2001 7223 7233
12. M. Takahashi, Y. Inaguma, H. Hiai, and F. Hirose Develop mentally regulated expression of a human 'finger'-containing gene encoded by the 5′ half of the ret transforming gene Mol. Cell. Biol. 8 1988 1853 1856
13. F. Grignani, M. Fagioli, M. Alcalay, L. Longo, P.P. Pandolfi, E. Donti, A. Biondi, F. Lo Coco, and P.G. Pelicci Acute promyelocytic leukemia: from genetics to treatment Blood 83 1994 10 25
14. B. Le Douarin The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18 EMBO J. 14 1995 2020 2033
15. Z.G. Wang, D. Ruggero, S. Ronchetti, S. Zhong, M. Gaboli, R. Rivi, and P.P. Pandolfi PML is essential for multiple apoptotic pathways Nat. Genet. 20 1998 266 272
16. F. Quignon, F. De Bels, M. Koken, J. Feunteun, J.C. Ameisen, and H. de The PML induces a novel caspase-independent death process Nat. Genet. 20 1998 259 265
17. S.H. Dho, and K.S. Kwon The Ret finger protein induces apoptosis via its RING finger-B box-coiled-coil motif J. Biol. Chem. 278 2003 31902 31908
18. T.I.F. Consortium Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever Cell 90 1997 797 807
19. N.A. Quaderi, S. Schweiger, K. Gaudenz, B. Franco, E.I. Rugarli, W. Berger, G.J. Feldman, M. Volta, G. Andolfi, S. Gilgenkrantz, R.W. Marion, R.C. Hennekam, J.M. Opitz, M. Muenke, H.H. Ropers, and A. Ballabio Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22 Nat. Genet. 17 1997 285 291
20. K. Avela, M. Lipsanen-Nyman, N. Idanheimo, E. Seemanova, S. Rosengren, T.P. Makela, J. Perheentupa, A.D. Chapelle, and A.E. Lehesjoki Gene encoding a new RING-B-box-coiled-coil protein is mutated in mulibrey nanism Nat. Genet. 25 2000 298 301
21. L. Zhou, C. Zhu, K. Luo, Y. Li, H. Pi, W. Yuan, Y. Wang, C. Huang, M. Liu, and X. Wu Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development Biochem. Biophys. Res. Commun. 295 2002 862 868
22. W. Zeng, W. Yuan, Y. Wang, W. Jiao, Y. Zhu, C. Huang, D. Li, Y. Li, C. Zhu, X. Wu, and M. Liu Expression of a novel member of sorting nexin gene family, SNX-L, in human liver development Biochem. Biophys. Res. Commun. 299 2002 542 548
23. C. Huang, Y. Wang, D. Li, Y. Li, J. Luo, W. Yuan, Y. Ou, C. Zhu, Y. Zhang, Z. Wang, X. Wu, and M. Liu Inhibition of transcriptional activities of AP-1 and c-Jun by a new zinc-finger protein ZNF394 Biochem. Biophys. Res. Commun. 320 2004 1298 1305
24. C. Xia, W. Ma, L.J. Stafford, S. Marcus, W.C. Xiong, and M. Liu Regulation of the p21-activated kinase (PAK) by a human G-beta-like WD-repeat protein, hPIP1 Proc. Natl. Acad. Sci. USA 98 2001 6174 6179
25. Y. Zhu, Y. Wang, C. Xia, D. Li, Y. Li, W. Zeng, W. Yuan, H. Liu, C. Zhu, X. Wu, M. Liu, WDR26, a novel G-beta-like protein, suppresses MAPK signaling pathway, J. Cell Biochem, (2004), in press. Published online 11 August 2004, doi:10.1002/jcb.20175
26. L. Venturini, J. You, M. Stadler, R. Galien, V. Lallemand, M.H. Koken, M.G. Mattei, A. Ganser, P. Chambon, R. Losson, and H. de Thé TIF1γ, a novel member of the transcriptional intermediary factor 1 family Oncogene 18 1999 1209 1217
27. H. Peng, I. Feldman, and F.J. Rauscher III Hetero-oligomerization Among the TIF Family of RBCC/TRIM motif-containing nuclear cofactors: a potential mechanism for regulating the switch between coactivation and corepression J. Mol. Biol. 320 2002 629 644
28. R.J. Davis MAPKs: new JN K expands the group Trends Biochem. Sci. 19 1994 470 473
29. J.M. Kyriakis, and J. Avruch Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation Physiol. Rev. 81 2001 807 869
30. R. Treisman Regulation of transcription by MAP kinase cascades Curr. Opin. Cell Biol. 8 1996 205 215
31. H. Gille, M. Kortenjann, O. Thomae, C. Moomaw, C. Slaughter, M.H. Cobb, and P.E. Shaw ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation EMBO J. 14 1995 951 962
32. F. Jeanmougin, J.D. Thompson, M. Gouy, D.G. Higgins, and T.J. Gibson Multiple sequence alignment with Clustal X Trends Biochem. Sci. 23 1998 403 405