RFP2, c13ORF1, and FAM10A4 are the most likely tumor suppressor gene candidates for B-cell chronic lymphocytic leukemia

Cancer Genetics and Cytogenetics

Volumn 146, Issue 1, 2003, Pages 48-57

  Van Everdink, W J ^a   Baranova, A ^b,c   Lummen, C ^a   Tyazhelova, T ^b   Looman, M W G ^a   Ivanov, D ^b,c   Verlind, E ^a   Pestova, A ^b   Faber, H ^a   Van Der Veen, A Y ^a   Yankovsky, N ^b   Vellenga, E ^d   Buys, C H C M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b VAVILOV INSTITUTE OF GENERAL GENETICS   (Russian Federation)

^c GEORGE MASON UNIVERSITY   (United States)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA;

AMINO ACID SEQUENCE; ARTICLE; B LYMPHOCYTE; CHRONIC LYMPHATIC LEUKEMIA; COSMID; EXON; EXTENSION GENE; GENE; GENE 10A4; GENE C13ORF1; GENE CONSTRUCT; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE RFP2; GENE SEQUENCE; GENETIC SCREENING; HUMAN; INHERITANCE; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PRIORITY JOURNAL; PROMOTER REGION; PUBLICATION; TUMOR SUPPRESSOR GENE;

EID: 0141453649     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(03)00126-2     Document Type: Article

References (45)

1. Liu Y., Hermanson M., Grander D., Merup M., Wu X., Heyman M., Rasool O., Juliusson G., Gahrton G., Detlofsson R. 13q deletions in lymphoid malignancies. Blood. 86:1995;1911-1915.
2. Dohner H., Stilgenbauer S., James M.R., Benner A., Weilguni T., Bentz M., Fischer K., Hunstein W., Lichter P. 11q deletions identify a new subset of B-cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis. Blood. 89:1997;2516-2522.
3. Liu Y., Corcoran M., Rasool O., Ivanova G., Ibbotson R., Grander D., Iyengar A., Baranova A., Kashuba V., Merup M., Wu X., Gardiner A., Mullenbach R., Poltaraus A., Hultstrom A.L., Juliusson G., Chapman R., Tiller M., Cotter F., Gahrton G., Yankovsky N., Zabarovsky E., Einhorn S., Oscier D. Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14 frequently deleted in chronic lymphocytic leukemia. Oncogene. 15:1997;2463-2473.
4. Corcoran M.M., Rasool O., Liu Y., Iyengar A., Grander D., Ibbotson R.E., Merup M., Wu X., Brodyansky V., Gardiner A.C., Juliusson G., Chapman R.M., Ivanova G., Tiller M., Gahrton G., Yankovsky N., Zabarovsky E., Oscier D.G., Einhorn S. Detailed molecular delineation of 13q14.3 loss in B-cell chronic lymphocytic leukemia. Blood. 91:1998;1382-1390.
5. Larramendy M.L., Siitonen S.M., Zhu Y., Hurme M., Vilpo L., Vilpo J.A., Knuutila S. Optimized mitogen stimulation induces proliferation of neoplastic B cells in chronic lymphocytic leukemia: significance for cytogenetic analysis. The Tampere Chronic Lymphocytic Leukemia group. Cytogenet Cell Genet. 82:1998;215-221.
6. Liu Y., Szekely L., Grander D., Soderhall S., Juliusson G., Gahrton G., Linder S., Inhorn S. Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene: evidence for a role of an adjacent locus. Proc Natl Acad Sci USA. 90:1993;8697-8701.
7. Brown A.G., Ross F.M., Dunne E.M., Steel C.M., Weir-Thompson E.M. Evidence for a new tumour suppressor locus (DBM) in human B-cell neoplasia telomeric to the retinoblastoma gene. Nat Genet. 3:1993;67-72.
8. Hawthorn L.A., Chapman R., Oscier D., Cowell J.K. The consistent 13q14 translocation breakpoint seen in chronic B-cell leukaemia (BCLL) involves deletion of the D13S25 locus which lies distal to the retinoblastoma predisposition gene. Oncogene. 8:1993;1415-1419.
9. Chapman R.M., Corcoran M.M., Gardiner A., Hawthorn L.A., Cowell J.K., Oscier D.G. Frequent homozygous deletions of the D13S25 locus in chromosome region 13q14 defines the location of a gene critical in leukaemogenesis in chronic B-cell lymphocytic leukaemia. Oncogene. 9:1994;1289-1293.
10. Jabbar S.A., Ganeshaguru K., Wickremasinghe R.G., Hoffbrand A.V., Foroni L. Deletion of chromosome 13 (band q14) but not trisomy 12 is a clonal event in B-chronic lymphocytic leukaemia (CLL). Br J Haematol. 90:1995;476-478.
11. Stilgenbauer S., Leupolt E., Ohl S., Weiss G., Schroder M., Fischer K., Bentz M., Lichter P., Dohner H. Heterogeneity of deletions involving RB-1 and the D13S25 locus in B-cell chronic lymphocytic leukemia revealed by fluorescence in situ hybridization. Cancer Res. 55:1995;3475-3477.
12. Lichter P, Stilgenbauer S, Nickolenko J, Weiss G, Leupolt E, Dohner H. Deletion mapping by FISH points to a novel potential tumor suppressor gene in B-CLL between D13S273 and D13S272. 87th Annual Meeting of the American Association for Cancer Research.
13. Bullrich F., Veronese M.L., Kitada S., Jurlander J., Caligiuri M.A., Reed J.C., Croce C.M. Minimal region of loss at 13q14 in B-cell chronic lymphocytic leukemia. Blood. 88:1996;3109-3115.
14. Bouyge-Moreau I., Rondeau G., Avet-Loiseau H., André M.T., Bézieau S., Chérel M., Saleün S., Cadoret E., Shaikh T., De Angelis M.M., Arcot S., Batzer M., Moisan J.P., Devilder M.C. Construction of a 780-kb PAC, BAC, and cosmid contig encompassing the minimal critical deletion involved in B cell chronic lymphocytic leukemia at 13q14.3. Genomics. 46:1997;183-190.
15. Kalachikov S., Migliazza A., Cayanis E., Fracchiolla N.S., Bonaldo M.F., Lawton L., Jelenc P., Ye X., Qu X., Chien M., Hauptschein R., Gaidano G., Vitolo U., Saglio G., Resegotti L., Brodjansky V., Yankovsky N., Zhang P., Soares M.B., Russo J., Edelman I.S., Efstratiadis A., Dalla-Favera R., Fischer S.G. Cloning and gene mapping of the chromosome 13q14 region deleted in chronic lymphocytic leukemia. Genomics. 42:1997;369-377.
16. Devilder M.C., Francois S., Bosic C., Moreau A., Mellerin M.P., Le Paslier D., Bataille R., Moisan J.P. Deletion cartography around the D13S25 locus in B cell chronic lymphocytic leukemia and accurate mapping of the involved tumor suppressor gene. Cancer Res. 55:1995;1355-1357.
17. Kapanadze B., Kashuba V., Baranova A., Rasool O., van Everdink W., Liu Y., Syomov A., Corcoran M., Poltaraus A., Brodyansky V., Syomova N., Kazakov A., Ibbotson R., van den Berg A., Gizatullin R., Fedorova L., Sulimova G., Zelenin A., Deaven L., Lehrach H., Grander D., Buys C., Oscier D., Zabarovsky E.R., Yankovsky N. A cosmid and cDNA fine physical map of a human chromosome 13q14 region frequently lost in B-cell chronic lymphocytic leukemia and identification of a new putative tumor suppressor gene Leu5. FEBS Lett. 426:1998;266-270.
18. Hawthorn L., Roberts T., Verlind E., Kooy R.F., Cowell J.K. A yeast artificial chromosome contig that spans the RB1-D13S31 interval on human chromosome 13 and encompasses the frequently deleted region in B-cell chronic lymphocytic leukemia. Genomics. 30:1995;425-430.
19. Brodyanskii V.M., Sulimova G., Udina I.G., Aitova S.S., Shaikhaev G.O., Sharikova O.A., Zakhar'ev V.M., Fedorova L.I., Zelenin A.V., Einhorn S., Buys C.H.C.M., Laland M., Ross M., Yankovsky N.K. Screening of YAC clones and building a map of the chromosome 13 region often deleted during chronic B-cell lymphocytic leucosis. Mol Biol. 29:1995;665-672.
20. Riley J., Butler R., Ogilvie D., Finniear R., Jenner D., Powell S., Anand R., Smith J.C., Markham A.F. A novel rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones. Nucleic Acids Res. 18:1990;2887-2890.
21. van der Steege G., Draaijers T.G., Grootscholten P.M., Osinga J., Anzevino R., Velona I., Den Dunnen J.T., Scheffer H., Brahe C., van Ommen G.J., Buys C.H.C.M. A provisional transcript map of the spinal muscular atrophy (SMA) critical region. Eur J Hum Genet. 3:1995;87-95.
22. Giles R.H., Petrij F., Dauwerse H.G., den Hollander A.I., Lushnikova T., van Ommen G.J., Goodman R.H., Deaven L.L., Doggett N.A., Peters D.J., Breuning M.H. Construction of a 1.2-Mb contig surrounding and molecular analysis of the human CREB-binding protein (CBP/CREBBP) gene on chromosome 16p13.3. Genomics. 42:1997;96-114.
23. Santos M.A. An improved method for the small scale preparation of bacteriophage DNA based on phage precipitation by zinc chloride. Nucleic Acids Res. 19:1991;5442.
24. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J Mol Biol. 215:1990;403-410.
25. Mertens D., Wolf S., Bullinger L., Ohl S., Schaffner C., Dohner H., Stilgenbauer S., Lichter P. BCMSUN a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma has an independently expressed homolog on 1p22-p31 BCMSUN-like. Int J Cancer. 88:2000;692-697.
26. Timmer T., Terpstra P., van den Berg A., Veldhuis P.M., Ter Elst A., Voutsinas G., Hulsbeek M.M., Draaijers T.G., Looman M.W., Kok K., Naylor S.L., Buys C.H.C.M. A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3. Eur J Hum Genet. 7:1999;478-486.
27. Takeda S., Fujiwara T., Shimizu F., Kawai A., Shinomiya K., Okuno S., Ozaki K., Katagiri T., Shimada Y., Nagata M., Watanabe T., Takaichi A., Kuga Y., Suzuki M., Hishigaki H., Takahashi E., Shin S., Nakamura Y., Hirai Y. Isolation and mapping of karyopherin alpha 3 (KPNA3) a human gene that is highly homologous to genes encoding Xenopus importin yeast SRP1 and human RCH1. Cytogenet Cell Genet. 76:1997;87-93.
28. Bézieau S., Devilder M.C., Rondeau G., Cadoret E., Moisan J.P., Moreau I. Assignment of 48 ESTs to chromosome 13 band q14.3 and expression pattern for ESTs located in the core region deleted in B-CLL. Genomics. 52:1998;369-373.
29. Hohfeld J., Minami Y., Hartl F.U. Hip, a novel cochaperone involved in the eukaryotic Hsc70/Hsp40 reaction cycle. Cell. 83:1995;589-598.
30. Cao J., Cai X., Zheng L., Shi Z., Pao C.C., Zheng S. Characterization of colorectal-cancer-related cDNA clones obtained by subtractive hybridization screening. J Cancer Res Clin Oncol. 123:1997;447-451.
31. Reymond A., Meroni G., Fantozzi A., Merla G., Cairo S., Luzi L., Riganelli D., Zanaria E., Messali S., Cainarca S., Guffanti A., Minucci S., Pelicci P.G., Ballabio A. The tripartite motif family identifies cell compartments. EMBO J. 20:2001;2140-2151.
32. Wolf S., Mertens D., Schaffner C., Korz C., Dohner H., Stilgenbauer S., Lichter P. B-cell neoplasia associated gene with multiple splicing (BCMS): the candidate B-CLL gene on 13q14 comprises more than 560 kb covering all critical regions. Hum Mol Genet. 10:2001;1275-1285.
33. Mabuchi H., Fujii H., Calin G., Alder H., Begrini M., Rassente L., Kipps T.J., Bullrich F., Croce C.M. Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia. Cancer Res. 61:2001;2870-2877.
34. Talcott B., Moore M.S. The nuclear import of RCC1 requires a specific nuclear localization sequence receptor, karyopherin alpha3/Qip. J Biol Chem. 275:2000;10099-10104.
35. Stilgenbauer S., Nickolenko J., Wilhelm J., Wolf S., Weitz S., Dohner K., Boehm T., Dohner H., Lichter P. Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma. Oncogene. 16:1998;1891-1897.
36. Sossey-Alaoui K., Kitamura E., Head K., Cowell J.K. Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with b-cell leukemia, multiple myeloma, and prostate cancer. Genomics. 80:2002;5-7.
37. Rondeau G., Moreau I., Bezieau S., Cadoret E., Moisan J.P., Devilder M.C. Exclusion of Leu1 and Leu2 genes as tumor suppressor genes in 13q14.3-deleted B-CLL. Leukemia. 13:1999;1630-1632.
38. Bullrich F., Fujii H., Calin G., Mabuchi H., Negrini M., Pekarsky Y., Rassenti L., Alder H., Reed J.C., Keating M.J., Kipps T.J., Croce C.M. Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene. Cancer Res. 61:2001;6640-6648.
39. Migliazza A., Bosch F., Komatsu H., Cayanis E., Martinotti S., Toniato E., Guccione E., Qu X., Chien M., Murty V.V., Gaidano G., Inghirami G., Zhang P., Fischer S., Kalachikov S.M., Russo J., Edelman I., Efstratiadis A., Dalla-Favera R. Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia. Blood. 97:2001;2098-2104.
40. Rondeau G., Moreau I., Bezieau S., Petit J.L., Heilig R., Fernandez S., Pennarun E., Myers J.S., Batzer M.A., Moisan J.P., Devilder M.C. Comprehensive analysis of a large genomic sequence at the putative B-cell chronic lymphocytic leukaemia (B-CLL) tumour suppresser gene locus. Mutat Res. 458:2001;55-70.
41. Mertens D., Wolf S., Schroeter P., Schaffner C., Dohner H., Stilgenbauer S., Lichter P. Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemia. Blood. 99:2002;4116-4121.
42. Chang H., Bouman D., Boerkoel C.F., Stewart A.K., Squire J.A. Frequent monoallelic loss of D13S319 in multiple myeloma patients shown by interphase fluorescence in situ hybridization. Leukemia. 13:1999;105-109.
43. Gupta V.K., Schmidt A.P., Pashia M.E., Sunwoo J.B., Scholnick S.B. Multiple regions of deletion on chromosome arm 13q in head-and-neck squamous-cell carcinoma. Int J Cancer. 22:1999;453-457.
44. Rosenwald A., Ott G., Krumdiek A.K., Dreyling M.H., Katzenberger T., Roth S., Ott M.M., Muller-Hermelink H.K. A biological role for deletions in chromosomal band 13q14 in mantle cell and peripheral t-cell lymphomas? Genes Chromosomes Cancer. 26:1999;210-214.
45. Ueda T., Emi M., Suzuki H., Komiya A., Akakura K., Ichikawa T., Watanebe M., Shiraishi T., Masai M., Igarashi T., Ito H. Identification of a 1-cM region of common deletion on 13q14 associated with human prostate cancer. Genes Chromosomes Cancer. 24:1999;183-190.