Hepatitis C NS5B polymerase inhibitors: Functional equivalents for the benzothiadiazine moiety

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 6, 2011, Pages 1876-1879

  Hutchinson, Douglas K ^a   Flentge, Charles A ^a   Donner, Pamela L ^a   Wagner, Rolf ^a   Maring, Clarence J ^a   Kati, Warren M ^a   Liu, Yaya ^a   Masse, Sherie V ^a   Middleton, Tim ^a   Mo, Hongmei ^a   Montgomery, Debra ^a   Jiang, Wen W ^a   Koev, Gennadiy ^a   Beno, David W A ^a   Stewart, Kent D ^a   Stoll, Vincent S ^a   Molla, Akhteruzzaman ^a   Kempf, Dale J ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Benzothiadiazine; Bioisosteres; Hepatitis C; NS5B polymerase inhibitors

Indexed keywords

BENZOTHIADIAZINE DERIVATIVE; NONSTRUCTURAL PROTEIN 5B; QUINOLINE DERIVATIVE; RNA DIRECTED RNA POLYMERASE; RNA DIRECTED RNA POLYMERASE INHIBITOR;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ASSAY; HEPATITIS C VIRUS; REPLICON;

BENZOTHIADIAZINES; HEPACIVIRUS; PROTEASE INHIBITORS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

HEPATITIS C VIRUS;

EID: 79952360002     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.12.067     Document Type: Article

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