The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Dao, Khanh K ^a   Pey, Angel L ^b   Gjerde, Anja Underhaug ^a   Teigen, Knut ^a   Byeon, In Ja L ^c   Døskeland, Stein O ^a   Gronenborn, Angela M ^c   Martinez, Aurora ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b UNIVERSITY OF GRANADA   (Spain)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT IALPHA; CYCLIC NUCLEOTIDE; PROTEIN SERINE THREONINE KINASE; CYCLIC AMP; THIAZOLE DERIVATIVE; THIOFLAVINE;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; ATOMIC FORCE MICROSCOPY; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; ENZYME DENATURATION; ENZYME STRUCTURE; HUMAN; HUMAN CELL; LIGHT SCATTERING; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; TEMPERATURE SENSITIVITY; CHEMISTRY; DRUG EFFECT; ENZYME STABILITY; FLUORESCENCE; LIGHT; METABOLISM; MOLECULAR DYNAMICS; PROTEIN DENATURATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN UNFOLDING; RADIATION SCATTERING; TEMPERATURE;

CALORIMETRY, DIFFERENTIAL SCANNING; CIRCULAR DICHROISM; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASE RIALPHA SUBUNIT; ENZYME STABILITY; FLUORESCENCE; HUMANS; LIGHT; MICROSCOPY, ATOMIC FORCE; MOLECULAR DYNAMICS SIMULATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN UNFOLDING; SCATTERING, RADIATION; TEMPERATURE; THIAZOLES;

EID: 79952323827     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017602     Document Type: Article

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