Erratum: Synaptic Dysbindin-1 Reductions in Schizophrenia Occur in an Isoform-Specific Manner Indicating Their Subsynaptic Location (PLoS ONE (2021) 6:3 (e16886) DOI: 10.1371/journal.pone.0016886);Synaptic dysbindin-1 reductions in schizophrenia occur in an isoform-specific manner indicating their subsynaptic location

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Talbot, Konrad ^a   Louneva, Natalia ^a   Cohen, Julia W ^a   Kazi, Hala ^a   Blake, Derek J ^b   Arnold, Steven E ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Cardiff University   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DYSBINDIN; DYSBINDIN 1A; DYSBINDIN 1B; DYSBINDIN 1C; ISOPROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; DTNBP1 PROTEIN, HUMAN;

AGED; ARTICLE; AUDITORY CORTEX; BRAIN REGION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NEUROPATHOLOGY; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SCHIZOPHRENIA; SPATIAL MEMORY; SUPERIOR TEMPORAL GYRUS; SYNAPTOSOME; TISSUE DISTRIBUTION; WESTERN BLOTTING; WORKING MEMORY; ANIMAL; ANTIBODY AFFINITY; AUTOPSY; CASE CONTROL STUDY; CELL FRACTIONATION; DEMOGRAPHY; METABOLISM; MOUSE; PATHOLOGY; SYNAPSE; TEMPORAL LOBE;

AGED; ANIMALS; ANTIBODY AFFINITY; AUTOPSY; CARRIER PROTEINS; CASE-CONTROL STUDIES; DEMOGRAPHY; FEMALE; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; PROTEIN ISOFORMS; SCHIZOPHRENIA; SUBCELLULAR FRACTIONS; SYNAPSES; SYNAPTOSOMES; TEMPORAL LOBE;

EID: 79952284133     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0301152     Document Type: Erratum

References (85)

1. Allen NC, Bagade S, McQueen MB, Ioannidis JPA, Kavvoura FK, et al. (2008) Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet 40: 827-834.
2. Sun J, Kuo P-H, Riley BP, Kendler KS, Zhao Z, (2008) Candidate genes for schizophrenia: a survey of association studies and gene ranking. Am J Med Genet B (Neuropsychiatr Genet) 147B: 1173-1181.
3. Réthelyi JM, Bakker SC, Polgár P, Czobor P, Strengman E, et al. (2009) Association study of NRG1, DTNBP1, RGS4, G72/G30, and PIP5K2A with schizophrenia and symptom severity in a Hungarian sample. Am J Med Genet B (Neuropsychiatr Genet) 153B: 792-801.
4. Riley B, Kuo P-H, Maher BS, Fanous AH, Sun J, et al. (2009) The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample. Schiz Res 115: 245-253.
5. Talbot K, Ong WY, Blake DJ, Tang J, Louneva N, et al. (2009) Dysbindin-1 and its protein family with special attention to the potential role of dysbindin-1 in neuronal functions and the pathophysiology of schizophrenia. In: Javitt D, Kantrowitz J, editors. Handbook of neurochemistry and molecular neurobiology, 3rd ed., vol. 27 (Schizophrenia) New York Springer US pp. 107-241.
6. Zuo L, Luo X, Kranzler HR, Lu L, Rosenheck RA, et al. (2009) Association study of DTNBP1 with schizophrenia in a US sample. Psychiatr Genet 19: 292-304.
7. Fanous AH, van den Oord EJ, Riley BP, Aggen SH, Neale MC, et al. (2005) Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophrenia. Am J Psychiatry 162: 1824-1832.
8. DeRosse P, Funke B, Burdick KE, Lencz T, Ekholm JM, et al. (2006) Dysbindin genotype and negative symptoms in schizophrenia. Am J Psychiatry 163: 532-534.
9. Pae C-U, Drago A, Kim J-J, Patkar AA, Jun T-Y, et al. (2008) DTNBP1 haplotype influences baseline assessment scores of schizophrenic in-patients. Neurosci Lett 440: 150-154.
10. Wirgenes KV, Djurovic S, Agartz I, Jönsson EG, Werge T, et al. (2009) Dysbindin and D-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia. Neuropsychobiology 60: 31-36.
11. Burdick KE, Lencz T, Funke B, Finn CT, Szeszko PR, et al. (2006) Genetic variation in DTNBP1 influences general cognitive ability. Hum Mol Genet 15: 1563-1568.
12. Burdick KE, Goldberg TE, Funke B, Bates JA, Lencz T, et al. (2007) DTNBP1 genotype influences cognitive decline in schizophrenia. Schizophr Res 89: 169-172.
13. Donohoe G, Morris DW, Clarke S, McGhee KA, Schwaiger S, et al. (2007) Variance in neurocognitive performance is associated with dysbindin-1 in schizophrenia: a preliminary study. Neuropsychologia 45: 454-458.
14. Zinkstok JR, deWilde O, van Amelsvoort TAMJ, Tanck MW, Linszen DH, (2007) Association between the DTNBP1 gene and intelligence: a case-control study in young patients with schizophrenia and related disorders and unaffected siblings. Behav Brain Funct 3: 19.
15. Wessman J, Paunio T, Tuulio-Henriksson A, Koivisto M, Partonen T, et al. (2009) Mixture model clustering of phenotype features reveals evidence for association of DTNBP1 to a specific subtype of schizophrenia. Biol Psychiatry 66: 990-996.
16. Talbot K, Eidem WL, Tinsley CL, Benson MA, Thompson EW, et al. (2004) Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia. J Clin Invest 113: 1353-1363.
17. Tang J, LeGros RP, Louneva N, Yeh L, Cohen JW, et al. (2009) Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression. Hum Mol Genet 18: 3851-3863.
18. Howard MA, Volkov IO, Mirsky R, Garell PC, Noh MD, et al. (2000) Auditory cortex on the human superior temporal cortex. J Comp Neurol 416: 79-92.
19. Sweet RA, Dorph-Petersen K-A, Lewis DA, (2005) Mapping auditory core, lateral belt, and parabelt cortices in the human superior temporal gyrus. J Comp Neurol 491: 270-289.
20. Brugge JF, Volkov IO, Oya H, Kawasaki H, Reale RA, et al. (2008) Functional localization of auditory cortical fields of human: click-train stimulation. Hearing Res 238: 12-24.
21. Smiley JF, (2009) Auditory Cortex Anatomy and Asymmetry in Schizophrenia. In: Javitt D, Kantrowitz J, editors. Handbook of neurochemistry and molecular neurobiology, 3rd ed., vol. 27 (Schizophrenia) New York Springer US pp. 353-381.
22. Deng C, Huang X-F, (2005) Decreased density of muscarinic receptors in the superior temporal gyrus in schizophrenia. J Neurosci Res 81: 883-890.
23. Deng C, Huang X-F, (2006) Increased density of GABAA receptors in the superior temporal gyrus in schizophrenia. Exp Brain Res 168: 587-590.
24. Heckers S, (2009) Hippocampus. In: Javitt D, Kantrowitz J, editors. Handbook of neurochemistry and molecular neurobiology, 3rd ed., vol. 27 (Schizophrenia) New York Springer US pp. 315-330.
25. Sweet RA, Bergen SE, Sun Z, Sampson AR, Pierri JN, et al. (2004) Pyramidal cell size reduction in schizophrenia: evidence for involvement of auditory feedforward circuits. Biol Psychiatry 55: 1128-1137.
26. Sweet RA, Bergen SE, Sun Z, Marcsisin MJ, Sampson AR, et al. (2007) Anatomical evidence of impaired feedforward auditory processing in schizophrenia. Biol Psychiatry 61: 854-864.
27. Sweet RA, Henteleff RA, Zhang W, Sampson AR, Lewis DA, (2009) Reduced dendritic spine density in auditory cortex of subjects with schizophrenia. Neuropsychopharamcology 34: 374-389.
28. Konopaske GT, Sweet RA, Wu Q, Sampson A, Lewis DA, (2006) Regional specificity of chandelier neuron axon terminal alterations in schizophrenia. Neuroscience 138: 189-196.
29. Chance SA, Casanova MF, Switala AE, Crow TJ, (2008) Auditory cortex asymmetry, altered minicolumn spacing and absence of ageing effects in schizophrenia. Brain 131: 3178-3192.
30. Takahashi T, Suzuki M, Zhou S-Y, Tanino R, Hagino H, et al. (2006) Morphological alterations of the parcellated superior temporal gyrus in schizophrenia spectrum. Schizophr Res 83: 131-143.
31. Velakoulis D, Wood SJ, Wong MTH, McGorry PD, Yung A, et al. (2006) Hippocampal and amygdala volumes according to psychosis stage and diagnosis, a magnetic resonance imaging study of chronic schizophrenia, first-episode psychosis, and ultra-high risk individuals. Arch Gen Psychiatry 63: 139-149.
32. Sun J, Maller JJ, Guo L, Fitzgerald PB, (2009) Superior temporal gyrus volume change in schizophrenia: a review on region of interest volumetric studies. Brain Res Rev 61: 14-32.
33. Kasai K, Shenton ME, Salisbury DF, Hirayasu Y, Lee C-U, et al. (2003) Progressive decrease of left superior temporal gyrus gray matter volume in patients with first-episode schizophrenia. Am J Psychiatry 160: 156-164.
34. Steen RG, Mull C, McClure R, Hamer RM, Lieberman JA, (2006) Brain volume in first-episode schizophrenia, systematic review and meta-analysis of magnetic resonance imaging studies. Brit J Psychiatry 188: 510-518.
35. Szeszko PR, Strous RD, Goldman RS, Ashtari M, Knuth KH, et al. (2002) Neuropsychological correlates of hippocampal volumes in patients experiencing a first episode of schizophrenia. Am J Psychiatry 159: 217-226.
36. Toulopoulou T, Grech A, Morris RG, Schulze K, McDonald C, et al. (2004) The relationship between volumetric brain changes and cognitive function: a family study on schizophrenia. Biol Psychiatry 56: 447-453.
37. Nestor PG, Kubicki M, Kuroki N, Gurrera RJ, Niznikiewicz M, et al. (2007) Episodic memory and neuroimaging of hippocampus and fornix in chronic schizophrenia. Psychiatry Res: Neuroimaging 155: 21-28.
38. Thoma RJ, Monnig M, Hanlon FM, Miller GA, Petropoulos H, et al. (2009) Hippocampus volume and episodic memory in schizophrenia. J Int Neuropsychol Soc 15: 182-195.
39. Sumich A, Chitnis XA, Fannon DG, O'Ceallaigh S, Doku VC, et al. (2005) Unreality symptoms and volumetric measures of Heschl's gyrus and planum temporal in first-episode psychosis. Biol Psychiatry 57: 947-950.
40. Neckelmann G, Specht K, Lund A, Ersland L, (2006) MR morphometry analysis of grey matter volume reduction in schizophrenia: association with hallucinations. Int J Neurosci 116: 9-23.
41. Aguilar EJ, Sanjuan J, García-Martí G, Lull JJ, Robles M, (2008) MR and genetics in schizophrenia: focus on auditory hallucinations. Eur J Radiol 67: 434-439.
42. García-Martí G, Aguilar EJ, Lull JJ, Martí-Bonmatí L, Escartí MJ, et al. (2008) Schizophrenia with auditory hallucinations: a voxel-based morphometric study. Prog Neuro-Psychopharamcol & Biol Psychiatry 32: 72-80.
43. Talbot K, Cho D-S, Ong W-Y, Benson MA, Han L-Y, et al. (2006) Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin. Hum Mol Genet 15: 3041-3054.
44. Phillips GR, Huang JK, Wang Y, Tanaka H, Shapiro L, et al. (2001) The presynaptic particle web: ultrastructure, composition, dissolution, and reconstitution. Neuron 32: 63-77.
45. Phillips GR, Florens L, Tanaka H, Khaing ZZ, Fidler L, et al. (2005) Proteomic comparison of two fractions derived from the transsynaptic scaffold. J Neurosci Res 81: 762-775.
46. Louneva N, Cohen JW, Han L-Y, Talbot K, Wilson RS, et al. (2008) Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease. Am J Pathol 173: 1488-1495.
47. Hahn CG, Banerjee A, MacDonald ML, Cho DS, Kamins J, et al. (2009) The post-synaptic density of human postmortem brain tissues: an experimental study paradigm for neuropsychiatric illnesses. PLoS One 4 (4): e5251.
48. Fountoulakis M, Hardmeier R, Höger H, Lubec G, (2001) Postmortem changes in the level of brain proteins. Exp Neurol 167: 86-94.
49. Chiba S, Hashimoto R, Hattori S, Yohda M, Lipska B, et al. (2006) Effect of antipsychotic drugs on DISC1 and dysbindin expression in mouse frontal cortex and hippocampus. J Neural Transm 113: 1337-1346.
50. Ultanir SK, Kim J-E, Hall BJ, Deerinck T, Ellisman M, Ghosh A, (2007) Regulation of spine morphology and spine density by NMDA receptor signaling in vivo. Proc Natl Acad USA 104: 19553-19558.
51. Karlsgodt KH, Robleto K, Trantham-Davidson H, Jairl C, Cannon TD, et al. (2011) Reduced dysbindin expression mediates NMDA receptor hypofunction and impaired working memory performance. Biol Psychiatry 69: 28-34.
52. Camargo LM, Collura V, Rain J-C, Mizuguchi K, Hermjakob H, et al. (2007) Disrupted in schizophrenia 1 interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. Mol Psychiatry 12: 74-86.
53. Falcón-Péréz JM, Dell'Angelica EC, (2002) The pallidin (Pldn) gene and the role of SNARE proteins in melanosome biogenesis. Pigment Cell Res 15: 82-86.
54. Nazarian R, Starcevic M, Spencer MJ, Dell'Angelica EC, (2006) Reinvestigation of the dysbindin subunit of BLOC-1 (biogenesis of lysosome-related organelles complex-1) as a dystrobrevin-binding protein. Biochem J 395: 587-598.
55. Park M, Salgado JM, Ostroff L, Helton TD, Robinson CG, et al. (2006) Plasticity-induced growth of dendritic spines by exocytic trafficking from recycling endosomes. Neuron 52: 817-830.
56. Alvarez VA, Sabatini BL, (2007) Anatomical and physiological plasticity of dendritic spines. Annu Rev Neurosci 30: 79-97.
57. Okabe S, (2007) Molecular anatomy of the postsynaptic density. Mol Cell Neurosci 34: 503-518.
58. Ryder PV, Faundez V, (2009) Schizophrenia: the "BLOC" may be in the endosomes. Sci Signal 2: pe66.
59. Stephan KE, Friston KJ, Frith CD, (2009) Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring. Schiz Bull 35: 509-527.
60. Uhlhaas PJ, Singer W, (2006) Neuronal synchrony in brain disorders: relevance for cognitive dysfunctions and pathophysiology. Neuron 52: 155-168.
61. Bramon E, Rabe-Hesketh S, Sham P, Murray RM, Frangou S, (2004) Meta-analysis of the P300 and P50 waveforms in schizophrenia. Schizophr Res 70: 315-329.
62. Näätänen R, Kähkönen S, (2009) Central auditory dysfunction in schizophrenia as revealed by the mismatch negativity (MMN) and its magnetic equivalent MMNn: a review. Int J Neuropsychopharm 12: 125-135.
63. Weickert CS, Rothmond DA, Hyde TM, Kleinman JE, Straub RE, (2008) Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients. Schiz Res 98: 105-110.
64. Locke M, Tinsley CL, Benson MA, Blake DJ, (2009) TRIM32 is an E3 ubiquitin ligase for dysbindin. Hum Mol Genet 18: 2344-2358.
65. Louneva N, Talbot K, Locke M, Cohen JW, Blake DJ, et al. (2009) Decreased TRIM32 in schizophrenia may alter synaptic regulation of dysbindin-1C and AMPA receptor recycling in the hippocampal formation. Society for Neuroscience Annual Meeting (Chicago, IL): abstract 155.10.
66. Numakawa T, Yagasaki Y, Ishimoto T, Okada T, Suzuki T, et al. (2004) Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia. Hum Mol Genet 13: 2699-2708.
67. Chen X-W, Feng Y-Q, Hoo C-J, Guo X-L, He X, et al. (2008) DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release. J Cell Biol 181: 791-801.
68. Dickman DK, Davis GW, (2009) The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis. Science 326: 1127-1130.
69. Jentsch JD, Tinsley M, Jairl C, Horowitz B, Seu E, et al. (2009) Dysbindin modulates prefrontal cortical glutamatergic circuits and working memory function in mice. Neuropsychopharmacology 34: 2601-2608.
70. Law AJ, Weickert CS, Hyde TM, Kleinman JE, Harrison PJ, (2004) Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines. Am J Psychiatry 161: 1848-1855.
71. Rosoklija G, Toomayan G, Ellis SP, Keilp J, Mann J, et al. (2000) Structural abnormalities of subicular dendrites in subjects with schizophrenia and mood disorders, preliminary findings. Arch Gen Psychiatry 57: 349-356.
72. Cox MM, Tucker AM, Tang J, Talbot K, Richer DC, et al. (2009) Neurobehavioral abnormalities in the sandy mouse, a dysbindin-1 mutant, on a C57BL/6J background. Genes Brain Behav 8: 390-397.
73. Talbot K, (2009) The sandy (sdy) mouse: a dysbindin-1 mutant relevant to schizophrenia research. Prog Brain Res 179 (Genetic models of schizophrenia): 87-94.
74. Bhardwaj SK, Baharnoori M, Sharif-Askari B, Kamath A, Williams S, et al. (2009) Behavioral characterization of dysbindin-1 deficient sandy mice. Behav Brain Res 197: 435-441.
75. Barch DM, (2005) The cognitive neuroscience of schizophrenia. Annu Rev Clin Neurosci 1: 321-353.
76. Hanlon FM, Weisend MP, Hamilton DA, Jones AP, Thoma RJ, et al. (2006) Impairment on the hippocampal-dependent virtual Morris water task in schizophrenia. Schizophr Res 87: 67-80.
77. Elvevåg B, Goldberg TE, (2000) Cognitive impairment in schizophrenia is the core of the disorder. Crit Rev Neurobiol 14: 1-21.
78. Kraus MS, Keefe RE, (2007) Cognition as an outcome measure in schizophrenia. Brit J Psychiatry 191 (suppl. 50): s46-s51.
79. Reichenberg A, Harvey PD, (2007) Neuropsychological impairments in schizophrenia: integration of performance-based and brain imaging studies. Psychol Bull 133: 833-858.
80. Arnold SE, Gur RE, Shapiro RM, Fisher KR, Moberg PJ, et al. (1995) Prospective clinicopathologic studies of schizophrenia: accrual and assessment of patients. Am J Psychiatry 152: 731-737.
81. American Psychiatric Association (1994) Diagnostic and statistics manual of mental disorders, 4th ed (DSM-IV) Washington, D.C. American Psychiatric Press.
82. Li Y-T, Woodruff-Pak DS, Trojanowski JQ, (1994) Amyloid plaques in cerebellar cortex and the integrity of Purkinje cell dendrites. Neurobiol Aging 15: 1-9.
83. Albert KA, Hemmings HC Jr, Adamo AIB, Potkin SG, Akbarian S, et al. (2002) Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia. Arch Gen Psychiatry 59: 705-712.
84. Hashimoto T, Arion D, Unger T, Maldonado-Aviles JG, Morris HM, et al. (2008) Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia. Mol Psychiatry 13: 147-161.
85. Nieuwenhuys R, Voogd J, van Huijzen C, (2008) The human central nervous system, 4th ed New York Springer.