Hippocampus volume and episodic memory in schizophrenia

Journal of the International Neuropsychological Society

Volumn 15, Issue 2, 2009, Pages 182-195

  Thoma, Robert J ^a,b,c   Monnig, Mollie ^b,c   Hanlon, Faith M ^a,b   Miller, Gregory A ^d   Petropoulos, Helen ^e   Mayer, Andrew R ^b   Yeo, Ron ^b,c   Euler, Matt ^b,c   Lysne, Per ^b,c   Moses, Sandra N ^f   Cañive, Jose M ^a,g  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b MIND RESEARCH NETWORK   (United States)

^c UNIVERSITY OF NEW MEXICO   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f ROTMAN RESEARCH INSTITUTE   (Canada)

^g NEW MEXICO VA HEALTH CARE SYSTEM   (United States)

Author keywords

Antipsychotic agents; Cognition; Magnetic resonance imaging; Memory; Neuropsychology; Temporal lobe

Indexed keywords

ADULT; ARTICLE; ATTENTION; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; EPISODIC MEMORY; FEMALE; GRAY MATTER; HIPPOCAMPUS; HUMAN; INTELLIGENCE QUOTIENT; MALE; MENTAL PERFORMANCE; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; SCHIZOPHRENIA; VERBAL MEMORY; VISUAL MEMORY; WHITE MATTER; HEMISPHERIC DOMINANCE; MEMORY DISORDER; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; STATISTICS;

ADULT; FEMALE; FUNCTIONAL LATERALITY; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY DISORDERS; NEUROPSYCHOLOGICAL TESTS; SCHIZOPHRENIA; STATISTICS AS TOPIC;

EID: 65449140961     PISSN: 13556177     EISSN: 14697661     Source Type: Journal    
DOI: 10.1017/S1355617709090225     Document Type: Article

References (79)

1. Andreone, N., Tansella, M., Cerini, R., Rambaldelli, G., Versace, A., Marrella, G., Perlini, C., Dusi, N., Pelizza, L., Balestrieri, M., Barbui, C., Nosé, M., Gasparini, A., & Brambilla, P. (2007). Cerebral atrophy and white matter disruption in chronic schizophrenia. European Archives of Psychiatry and Clinical Neuroscience, 257, 3-11.
2. Bayley, P.J., O'Reilly, R.C., Curran, T., & Squire, L.R. (2008). New semantic learning in patients with large medial temporal lobe lesions. Hippocampus, 18, 575-583.
3. Bilder, R.M., Bogerts, B., Ashtari, M., Wu, H., Alvir, JM., Jody, D., Reiter, G., Bell, L., & Lieberman, J.A. (1995). Anterior hippocampal volume reductions predict frontal lobe dysfunction in first episode schizophrenia. Schizophrenia Research, 17, 47-58.
4. Bogerts, B., Ashtari, M., Degreef, G., Alvir, J.M.J., Bilder, R.M., & Lieberman, J.A. (1990). Reduced temporal limbic structure volumes on magnetic resonance images in first episode schizophrenia. Psychiatry Research: Neuroimaging, 35, 1-13.
5. Bogerts, B., Lieberman, J.A., Ashtari, M., Bilder, R.M., Degreef, G., Lerner, G., Johns, C., & Masiar, S. (1993). Hippocampusamygdala volumes and psychopathology in chronic schizophrenia. Biological Psychiatry, 33, 236-246.
6. Brewer, W.J., Francey, S.M., Wood, S.J., Pantelis, C., Phillips, L.J., Yung, A.R., Anderson, V.A., & McGorry, P.D. (2005). Memory impairments identified in people at ultra-high risk for psychosis who later develop first-episode psychosis. American Journal of Psychiatry, 192, 71-78.
7. Chakos, M.H., Schobel, S.A., Gu, H., Gerig, G., Bradford, D., Charles, C., & Lieberman, J.A. (2005). Duration of illness and treatment effects on hippocampal volume in male patients with schizophrenia. British Journal of Psychiatry, 186, 26-31.
8. Chapman, L.J., Chapman, J.P., Kwapil, T.R., & Eckblad, M. (1994). Putatively psychosis-prone subjects 10 years later. Journal of Abnormal Psychology, 103, 171-183.
9. Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ : Erlbaum.
10. Conners, C.K. (2000). Conners' CPT II: Continuous Performance Test II Computer program for Windows. North Tonawanda, NY : Multi-Health Systems.
11. DeLisi, L.E., Hoff, A.L., Schwartz, J.E., Shields, G.W., Halthore, S.N., Gupta, S.M., Henn, F.A., & Anand, A.K. (1991). Brain morphology in first-episode schizophrenic-like psychosis: A quantitative magnetic resonance imaging study. Biological Psychiatry, 29, 159-175.
12. Driscoll, I., Hamilton, D.A., Petropoulos, H., Yeo, R.A., Brooks, W.A., Baumgartner, R.N., & Sutherland, R.J. (2003). The aging hippocampus: Cognitive, biochemical and structural findings. Cerebral Cortex, 13, 1344-1351.
13. Eckblad, M. & Chapman, L. (1983). Magical ideation as an indicator of schizotypy. Journal of Consulting and Clinical Psychology, 51, 215-225.
14. Ellison-Wright, I., Glahn, D.C., Laird, A.R., Thelen, S.M., & Bullmore, E. (2008). The anatomy of first-episode and chronic schizophrenia: An anatomical likelihood estimation analysis. American Journal of Psychiatry: AJP in Advance, AiA : 1-9.
15. Eyler, L.T., Jeste, D.V., & Brown, G.G. (2008). Brain response abnormalities during verbal learning among patients with schizophrenia. Psychiatry Research: Neuroimaging, 162, 11-25.
16. First, M.B., Spitzer, R.L, Gibbon, M., & Williams, J.B.W. (1996). Structured Clinical Interview for DSM-IV Axis I Disorders, Clinician Version (SCID-CV). Washington, DC: American Psychiatric Press.
17. Gold, J.M., Randolph, C., Carpenter, C.J., Goldberg, T.E., & Weinberger, D.R (1992). Forms of memory failure in schizophrenia. Journal of Abnormal Psychology, 101, 487-494.
18. Goldberg, T.E., Torrey, E.F., Berman, K.F., & Weinberger, D.R. (1994). Relations between neuropsychological performance and brain morphological and physiological measures in monozygotic twins discordant for schizophrenia. Psychiatry Research: Neuroimaging, 55, 51-61.
19. Goldberg, T.E., Torrey, E.F., Gold, J.M., Ragland, J.D., Bigelow, L.B., & Weinberger, D.R. (1993). Learning and memory in monozygotic twins discordant for schizophrenia. Psychological Medicine, 23, 71-85.
20. Gothelf, D., Soreni, N., Nachman, R.P., Tyano, S., Hiss, Y., Reiner, O., & Weizman, A. (2000). Evidence for the involvement of the hippocampus in the pathophysiology of schizophrenia. European Neuropsychopharmacology, 10, 389-395.
21. Griffith, H.R., Pyzalski, R.W., Seidenberg, M., & Hermann, B.P. (2004). Memory relationships between MRI volumes and resting PET metabolism of temporal lobe structures. Epilepsy and Behavior, 5, 669-676.
22. Gruzelier, J., Seymour, K., Wilson, L., Jolley, A., & Hirsch, S. (1988). Impairments on neuropsychological tests of temporohippocampal and frontohippocampal functions and word fluency in remitting schizophrenia and affective disorders. Archives of General Psychiatry, 45, 623-629.
23. Gur, R.E., Turetsky, B.I., Cowell, P.E., Finkelman, C., Maany, V., Grossman, R.I., Arnold, S.E., Bilker, W.B., & Gur, R.C. (2000). Temporolimbic volume reductions in schizophrenia. Archives of General Psychiatry, 57, 769-775.
24. Hanlon, F.M., Weisend, M.P., Yeo, R.A., Huang, M., Lee, R.R., Thoma, R.J., Moses, S.N., Paulson, K.M., Miller, G.A., & Cañive, J.M. (2005). A specific test of hippocampal deficit in schizophrenia. Behavioral Neuroscience, 119, 863-875.
25. Heckers, S., Rauch, S.L., Goff, C.R., Schacter, D.L., Fischman, A.J., & Alpert., N.M. (1998). Impaired recruitment of hippocampus during conscious recollection in schizophrenia. Nature Neuroscience, 1, 318-323.
26. Hickie, I., Naismith, S., Ward, P.B., Turner, K., Scott, E., Mitchell, P., Wilhelm, K., & Parker, G. (2005). Reduced hippocampal volumes and memory loss in patients with early- and late-onset depression. British Journal of Psychiatry, 186, 197-202.
27. Hirayasu, Y., Shenton, M.E., Salisbury, D.F., Dickey, C.C., Fischer, I.A., Mazzoni, P.M., Kisler, T., Arakaki, H., Kwon, J.S., Anderson, J.E., Yurgelun-Todd, D., Tohen, M., & McCarley, R.W. (1998). Lower left temporal lobe MRI volumes in patients with first-episode schizophrenia compared with psychotic patients with first-episode affective disorder and normal subjects. American Journal of Psychiatry, 155, 1384-1391.
28. Honea, R., Crow, T.J., Passingham, D., & Mackay, C.E. (2005). Regional deficits in brain volume in schizophrenia: A metaanalysis of voxel-based morphometry studies. American Journal of Psychiatry, 162, 2233-2245.
29. Jessen, F., Scheef, L., Germeshausen, L., Tawo, Y., Kockler, M., Kuhn, K., Maier, W., Schild, H.H., & Heun, R. (2003). Reduced hippocampal activation during encoding and recognition of words in schizophrenia patients. American Journal of Psychiatry, 160, 1305-1312.
30. Kramer, J.H., Rosen, H.J., Du, A.-T., Schuff, N., Hollnagel, C., Weiner, M.W., Miller, B.L., & Delis, D.C. (2005). Dissociations in hippocampal and frontal contributions to episodic memory performance. Neuropsychology, 19, 799-805.
31. Kramer, J.H., Schuff, N., Reed, B.R., Mungas, D., Du, A.-T., Rosen, H.J., Jagust, W.J., Miller, B.L., Weiner, M.W., & Chui, H.C. (2004). Hippocampal volume and retention in Alzheimer's disease. Journal of the International Neuropsychological Society, 10, 639-643.
32. Kuroki, N., Kubicki, M., Nestor, P.G., Salisbury, D.F., Park, H.-J., Levitt, J.J., Woolston, S., Frumin, M., Niznikiewicz, M., Westin, C.-F., Maier, S.E., & Shenton, M.E. (2006). Fornix integrity and hippocampal volume in male schizophrenic patients. Biological Psychiatry, 60, 22-31.
33. Lieberman, J., Chakos, M., Wu, H., Alvir, J., Hoffman, E., Robinson, D., & Bilder, R. (2001). Longitudinal study of brain morphology in first episode schizophrenia. Biological Psychiatry, 49, 487-499.
34. Maguire, E.A., Gadian, D.G., Johnsrude, I.S., Good, C.D., Ashburner, J., Frackowiak, R.S.J., & Frith, C.D. (2000). Navigation-related structural change in the hippocampi of taxi drivers. Proceedings of the National Academy of Sciences, USA, 97, 4398-4403.
35. Marsh, L., Harris, D., Lim, K.O., Beal, M., Hoff, A.L., Minn, K., Csernansky, J.G., DeMent, S., Faustman, W.O., Sullivan, E.V., & Pfefferbaum, A. (1997). Structural magnetic resonance imaging abnormalities in men with severe chronic schizophrenia and an early age at clinical onset. Archives of General Psychiatry, 54, 1104-1112.
36. McCarley, R.W., Wible, C.G., Frumin, M., Hirayasu, Y., Levitt, J.J., Fischer, I.A., & Shenton, M.E. (1999). MRI anatomy of schizophrenia. Biological Psychiatry, 45, 1099-1119.
37. Miller, G.M. & Chapman, J.P. (2001). Misunderstanding analysis of covariance. Journal of Abnormal Psychology, 110, 40-48.
38. Milner, B. (2005). The medial temporal-lobe amnesic syndrome. Psychiatric Clinics of North America, 28, 599-611.
39. Mungas, D., Harvey, D., Reed, B.R., Jagust, W.J., DeCarli, C., Beckett, L., Mack, W.J., Kramer, J.H., Weiner, M.W., Schuff, N., & Chui, H.C. (2005). Longitudinal volumetric MRI change and rate of cognitive decline. Neurology, 65, 565-571.
40. Narr, K.L., Thompson, P.M., Sharma, T., Moussai, J., Blanton, R., Anvar, B., Edris, A., Krupp, R., Rayman, J., Khaledy, M., & Toga, A.W. (2001). Three-dimensional mapping of temporolimbic regions and the lateral ventricles in schizophrenia: Gender effects. Biological Psychiatry, 50, 84-97.
41. Narr, K.L., Thompson, P.M., Szezsko, P., Robinson, D., Jang, S., Woods, R.P., Kim, S., Hayashi, K.M., Asunction, D., Toga, A.W., & Bilder, R.M. (2004). Regional specificity of hippocampal volume reductions in first-episode schizophrenia. NeuroImage, 21, 1563-1575.
42. Nelson, M.D., Saykin, A.J., Flashman, L.A., & Riordan, H.J. (1998). Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging. Archives of General Psychiatry, 55, 433-440.
43. Nemeroff, C.B., Bremner, J.D., Foa, E.B., Mayberg, H.S., North, C.S., & Stein, M.B. (2006). Post-traumatic stress disorder: A state-of-the-science review. Journal of Psychiatric Research, 40, 1-21.
44. Nestor, P.G., Kubicki, M., Kuroki, N., Gurrera, R.J., Niznikiewicz, M., Shenton, M.E., & McCarley, R.W. (2007). Episodic memory and neuroimaging of hippocampus and fornix in chronic schizophrenia. Psychiatry Research: Neuroimaging, 155, 21-28.
45. O'Driscoll, G.A., Florencio, P.S., Gagnon, D., Wolff, A.V., Benkelfat, C., Mikula, L., Lal, S., & Evans, A.C. (2001). Amygdalahippocampal volume and verbal memory in first-degree relatives of schizophrenic patients. Psychiatry Research: Neuroimaging, 107, 75-85.
46. Öngür, D., Cullen, T.J., Wolf, D.H., Rohan, M., Barreira, P., Zalesak, M., & Heckers, S. (2006). The neural basis of relational memory deficits in schizophrenia. Archives of General Psychiatry, 63, 356-365.
47. Pegues, M.P., Rogers, L.J., Amend, D., Vinogradov, S., & Deicken, R.F. (2003). Anterior hippocampal volume reduction in male patients with schizophrenia. Schizophrenia Research, 60, 105-115.
48. Petersen, R.C., Jack, C.R. Jr., Xu, Y.-C., Waring, S.C., O'Brien, P.C., Smith, G.E., Ivnik, R.J., Tangalos, E.G., Boeve, B.F., & Kokmen, E. (2000). Memory and MRI-based hippocampal volumes in aging and AD. Neurology, 54, 581-587.
49. Petropoulos, H., Sibbitt, W.L., & Brooks, W.M. (1999). Automated T2 quantitation in neuropsychiatric lupus erythematosus: A marker of active disease. Journal of Magnetic Resonance Imaging, 9, 39-43.
50. Reminger, S.L., Kaszniak, A.W., Labiner, D.M., Littrell, L.D., David, B.T., Ryan, L., Herring, A.M., & Kaemingk, K.L. (2004). Bilateral hippocampal volume predicts verbal memory function in temporal lobe epilepsy. Epilepsy & Behavior, 5, 687-695.
51. Sachdev, P., Brodaty, H., Cheang, D., & Cathcart, S. (2000). Hippocampus and amygdala volumes in elderly schizophrenic patients as assessed by magnetic resonance imaging. Psychiatry and Clinical Neurosciences, 54 105-112.
52. Sanfilipo, M., Lafargue, T., Rusinek, H., Arena, L., Loneragan, C., Lautin, A., Feiner, D., Rotrosen, J., & Wolkin, A. (2000). Volumetric measure of the frontal and temporal lobe regions in schizophrenia: Relationship to negative symptoms. Archives of General Psychiatry, 57 471-480.
53. Sanfilipo, M., Lafargue, T., Rusinek, H., Arena, L., Loneragan, C., Lautin, A., Rotrosen, J., & Wolkin, A. (2002). Cognitive performance in schizophrenia: Relationship to regional brain volumes and psychiatric symptoms. Psychiatry Research, 116, 1-23.
54. Saykin, A.J., Gur, R.C., Gur, R.E., Mozley, P.D., Mosley, L.H., Resnick, S.M., Kester, B., & Stafaniak, P. (1991). Neuropsychological function in schizophrenia. Archives of General Psychiatry, 48, 618-624.
55. Saykin, A.J., Shtasel, D.L., Gur, R.E., Kester, D.B., Mozley, L.H., Stafiniak, P., & Gur, R.C. (1994). Neuropsychological deficits in neuroleptic naïve patients with first-episode schizophrenia. Archives of General Psychiatry, 51, 124-131.
56. Seidman, L.J., Faraone, S.V., Goldstein, J.M., Kremen, W.S., Horton, N.J., Makris, N., Toomey, R., Kennedy, D., Caviness, V.S., & Tsuang, M.T. (2002). Left hippocampal volume as a vulnerability indicator for schizophrenia. Archives of General Psychiatry, 59, 839-849.
57. Shenton, M.E., Kikinis, R., Jolesz, F.A., Pollak, S.D., LeMay, M., Wible, C.G., Hokama, H., Martin, J., Metcalf, D., Coleman, M., & McCarley, R.W. (1992). Abnormalities of the left temporal lobe and thought disorder in schizophrenia: A quantitative magnetic resonance imaging study. New England Journal of Medicine, 327, 604-612.
58. Shipley, W.C. (1940). A self-administered scale for measuring intellectual impairment and deterioration. Journal of Psychology, 9 371-377.
59. Silver, H., Feldman, P., Bilker, W., & Gur, R.C. (2003). Working memory as a core neuropsychological dysfunction in schizophrenia. American Journal of Psychiatry, 160, 1809-1816.
60. Steen, R.G., Mull, C., McClure, R. Hamer, R.M., & Lieberman, J.A. (2006). Brain volume in first-episode schizophrenia. British Journal of Psychiatry, 188, 510-518.
61. Sullivan, E.V., Marsh, L., Mathalon, D.H., Lim, K.O., & Pfefferbaum, A. (1995). Age-related decline in MRI volumes of temporal lobe gray matter but not hippocampus. Neurobiology of Aging, 16, 591-606.
62. Sweatt, J.D. (2004). Hippocampal function in cognition. Psychopharmacology, 174, 99-110.
63. Szeszko, P.R., Goldberg, E., Gunduz-Bruce, H., Ashtari, M., Robinson, D., Malhotra, A.K., Lencz, T., Bates, J., Crandall, D.T., Kane, J.M., & Bilder, R.M. (2003). Smaller anterior hippocampal formation in antipsychotic-naïve patients with first-episode schizophrenia. American Journal of Psychiatry, 160, 2190-2197.
64. Szezsko, P.R., Strous, R.D., Goldman, R.S., Ashtari, M., Knuth, K.H., Lieberman, J.A., & Bilder, R.M. (2002). Neuropsychological correlates of hippocampal volumes in patients experiencing a first episode of schizophrenia. American Journal of Psychiatry, 159, 217-226.
65. Tamlyn, D., McKenna, P.J., Mortimer, A.M., Lund, C.E., Hammond, S., & Baddeley, A.D. (1992). Memory impairment in schizophrenia: Its extent, affi liations and neuropsychological character. Psychological Medicine, 22, 101-115.
66. Thoma, R.J., Hanlon, F.M., Moses, S.N., Ricker, D., Huang, M., Edgar, C., Irwin, J., Torres, F., Weisend, M.P., Adler, L.E., Miller, G.A., & Cañive, J.M. (2005). M50 sensory gating predicts negative symptoms in schizophrenia. Schizophrenia Research, 73, 311-318.
67. Thoma, R.J., Hanlon, F.M., Petropoulos, H., Miller, G.A., Moses, S.N., Smith, A., Parks, L., Lundy, S.L., Sanchez, N.M., Jones, A., Huang, M., Weisend, M.P., & Cañive, J.M. (2008). Schizophrenia diagnosis and anterior hippocampal volume make separate contributions to sensory gating. Psychophysiology, 45(6), 926-935.
68. Torres, I.J., Flashman, L.A., O'Leary, D.S., Swayze, V. II, & Andreasen, N.C. (1997). Lack of an association between delayed memory and hippocampal and temporal lobe size in patients with schizophrenia and healthy controls. Biological Psychiatry, 42, 1087-1096.
69. Toulopoulou, T., Grech, A., Morris, R.G., Schulze, K., McDonald, C., Chapple, B., Rabe-Hesketh, S., & Murray, R.M. (2004). The relationship between volumetric brain changes and cognitive function: A family study on schizophrenia. Biological Psychiatry, 56, 447-453.
70. Van Petten, C. (2004). Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: Review and meta-analysis. Neuropsychologia, 42, 1394-1413.
71. Velakoulis, D., Wood, S.J., Wong, M.T.H., McGorry, P.D., Yung, A., Phillips, L., Smith, D., Brewer, W., Proffitt, T., Desmond, P., & Pantelis, C. (2006). Hippocampal and amygdala volumes according to psychosis stage and diagnosis. Archives of General Psychiatry, 63, 139-149.
72. Walhovd, K.B., Fjell, A.M., Reinvang, I., Lundervold, A., Fishl, B., Quinn, B.T., & Dale, A.M. (2004). Size does matter in the long run: Hippocampal and cortical volume predict recall across weeks. Neurology, 63, 1193-1197.
73. Watson, C., Andermann, F., Gloor, P., Jones-Gotman, M., Peters, T., Evans, A., Olivier, A., Melanson, D., & Leroux, G. (1992). Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging. Neurology, 42, 1743-1750.
74. Wechsler, D. (1987). Wechsler Memory Scale-Revised manual. New York : Psychological Corporation.
75. Weiss, A.P., DeWitt, I., Goff, D., Ditman, T., & Heckers, S. (2005). Anterior and posterior hippocampal volumes in schizophrenia. Schizophrenia Research, 73, 103-112.
76. White, T., Cullen, K., Rohrer, L.M., Karatekin, C., Luciana, M., Schmidt, M., Hongwanishkul, D., Kumra, S., Schulz, S.C., & Lim, K.O. (2008). Limbic structures and networks in children and adolescents with schizophrenia. Schizophrenia Bulletin, 34, 18-29.
77. Wright, I.C., Rabe-Hesketh, S., Woodruff, P.W.R., David, A.S., Murray, R.M., & Bullmore, E.T. (2000). Meta-analysis of regional brain volumes in schizophrenia. American Journal of Psychiatry, 157, 16-25.
78. Yeo, R.A., Gangestad, S.G., & Thoma, R.J. (2007). Developmental instability and individual variation in brain development: Implications for the etiology of neurodevelopmental disorders. Current Directions in Psychological Science, 15, 245-249.
79. Zipursky, R.B., Lambe, E.K., Kapur, S., & Mikulis, D.J. (1998). Cerebral gray matter volume deficits in first episode psychosis. Archives of General Psychiatry, 55, 540-546.