The relationship between volumetric brain changes and cognitive function: A family study on schizophrenia

Biological Psychiatry

Volumn 56, Issue 6, 2004, Pages 447-453

  Toulopoulou, Timothea ^a   Grech, Anton ^a   Morris, Robin G ^a   Schulze, Katja ^a   McDonald, Colm ^a   Chapple, Ben ^a   Rabe Hesketh, Sophia ^b   Murray, Robin M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cognition; executive processing; intelligence; intelligence quotient; magnetic resonance imaging; memory

Indexed keywords

ADULT; ARTICLE; BRAIN SIZE; BRAIN THIRD VENTRICLE; CEREBELLUM; COGNITION; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HIPPOCAMPUS; HUMAN; INTELLIGENCE; INTELLIGENCE QUOTIENT; LATERAL BRAIN VENTRICLE; MAJOR CLINICAL STUDY; MALE; MEMORY; MENTAL FUNCTION; NUCLEAR MAGNETIC RESONANCE IMAGING; PREFRONTAL CORTEX; PRIORITY JOURNAL; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; STRUCTURE ACTIVITY RELATION; TEMPORAL LOBE; VOLUMETRY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRAIN; BRAIN MAPPING; COGNITION DISORDERS; FAMILY HEALTH; FEMALE; HUMANS; INTELLIGENCE; INTELLIGENCE TESTS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PROBLEM SOLVING; PSYCHOTIC DISORDERS; SCHIZOPHRENIA; STATISTICS; VERBAL LEARNING;

EID: 4444250625     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2004.06.026     Document Type: Article

References (48)

1. D.N. Allen, G. Goldstein, C. Weiner Differential neuropsychological patterns of frontal- and temporal-lobe dysfunction in patients with schizophrenia Schizophr Res 48 2001 7 15
2. M. Allin, H. Matsumoto, A.M. Santhouse, C. Nosarti, M.H.S. Alasady, A.L Stewart Cognitive and motor function and the size of the cerebellum in adolescents born very pre-term Brain 124 2001 60 66
3. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders 4th ed 1994 American Psychiatric Association Washington, DC
4. N.C. Andreasen, L. Flashman, M. Flaum, S. Arndt, V. Swayze, D.S Oleary Regional brain abnormalities in schizophrenia measured with magnetic-resonance- imaging JAMA 272 1994 1763 1769
5. N.C. Andreasen, M. Flaum, V. Swayze, D.S. Oleary, R. Alliger, G Cohen Intelligence and brain structure in normal individuals Am J Psychiatry 150 1993 130 134
6. N.C. Andreasen, S. Paradiso, D.S. O'Leary "Cognitive dysmetria" as an integrative theory of schizophrenia A dysfunction in cortical subcortical-cerebellar circuitry? Schizophr Bull 24 1998 203 218
7. W.F.C. Baare, C.J. van Oel, H.E.H. Pol, H.G. Schnack, S. Durston, M.M Sitskoorn Volumes of brain structures in twins discordant for schizophrenia Arch Gen Psychiatry 58 2001 33 40
8. P.E. Barta, R.E. Powers, E.H. Aylward, G.A. Chase, G.J. Harris, P.V Rabins Quantitative MRI volume changes in late onset schizophrenia and Alzheimer's disease compared to normal controls Psychiatry Res 68 1997 65 75
9. J.S. Bedwell, B. Keller, A.K. Smith, S. Hamburger, S. Kumra, J.L. Rapoport Why does postpsychotic IQ decline in childhood-onset schizophrenia? Am J Psychiatry 156 1999 1996 1997
10. R.M. Bilder, B. Bogerts, M. Ashtari, H.W. Wu, J.M. Alvir, D Jody Anterior hippocampal volume reductions predict frontal-lobe dysfunction in first episode schizophrenia Schizophr Res 17 1995 47 58
11. R. Cabeza, F. Dolcos, R. Graham, L. Nyberg Similarities and differences in the neural correlates of episodic memory retrieval and working memory Neuroimage 16 2002 317 330
12. T.D. Cannon, M.O. Huttunen, J. Lonnqvist, A. Tuulio-Henriksson, T. Pirkola, D Glahn The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia Am J Hum Genet 67 2000 369 382
13. L.L. Davidson, R.W. Heinrichs Quantification of frontal and temporal lobe brain-imaging findings in schizophrenia A meta-analysis Psychiatry Res 122 2003 69 87
14. L.E. Delisi, A.L. Hoff, J.E. Schwartz, G.W. Shields, S.N. Halthore, S.M Gupta Brain morphology in 1st-episode schizophrenic-like psychotic patients - a quantitative magnetic-resonance-imaging study Biol Psychiatry 29 1991 159 175
15. J.E. Desmond Cerebellar involvement in cognitive function Evidence from neuroimaging Int Rev Psychiatry 13 2001 283 294
16. S. Frangou, T. Sharma, G. Alarcon, T. Sigmudsson, N. Takei, C Binnie The Maudsley family study 2. Endogenous event-related potentials in familial schizophrenia Schizophr Res 23 1997 45 53
17. S. Frangou, T. Sharma, T. Sigmudsson, P. Barta, G. Pearlson, R.M. Murray The Maudsley Family Study 4. Normal planum temporale asymmetry in familiar schizophrenia - a volumetric MRI study Br J Psychiatry 170 1997 328 333
18. T.E. Goldberg, E.F. Torrey, K.F. Berman, D.R. Weinberger Relations between neuropsychological performance and brain morphological and physiological measures in monozygotic twins discordant for schizophrenia Psychiatry Res 55 1994 51 61
19. T.D. Griffiths, T. Sigmundsson, N. Takei, S. Frangou, P.B. Birkett, T Sharma Minor physical anomalies in familial and sporadic schizophrenia The Maudsley family study Journal of Neurology Neurosurgery and Psychiatry 64 1998 56 60
20. E.A. Hazlett, M.S. Buchsbaum, R.C. Mohs, J. Spiegel-Cohen, T.C. Wei, R Azueta Age-related shift in brain region activity during successful memory performance Neurobiol Aging 19 1998 437 445
21. R.W. Heinrichs, K.K. Zakzanis Neurocognitive deficit in schizophrenia A quantitative review of the evidence Neuropsychology 12 1998 426 445
22. T.C. Justus, R.B. Ivry The cognitive neuropsychology of the cerebellum Int Rev Psychiatry 13 2001 276 282
23. S.M. Lawrie, H. Whalley, J.N. Kestelman, S.S. Abukmeil, M. Byrne, A Hodges Magnetic resonance imaging of brain in people at high risk of developing schizophrenia Lancet 353 1999 30 33
24. C. McDonald, A. Grech, T. Toulopoulou, K. Schulze, B. Chapple, P Sham Brain volumes in familial and non-familial schizophrenic probands and their unaffected relatives Am J Med Genet 114 2002 616 625
25. R.G. Morris, J.J. Downes, B.J. Sahakian, J.L. Evenden, A. Heald, T.W. Robbins Planning and spatial working memory in Parkinson's disease J Neurol Neurosurg Psychiatry 51 1988 757 766
26. R.G. Morris, T. Rushe, P.W.R. Woodruffe, R.M. Murray Problem-solving in schizophrenia A specific deficit in planning ability Schizophr Res 14 1995 235 246
27. R.M. Murray, S.W. Lewis Is schizophrenia a neurodevelopmental disorder? Br Med J 295 1987 681 682
28. G.A. O'Driscoll, P.S. Florencio, D. Gagnon, A.V. Wolff, C. Benkelfat, L Mikula Amygdala-hippocampal volume and verbal memory in first-degree relatives of schizophrenic patients Psychiatry Res 107 2001 75 85
29. A.M. Owen, J.J. Downes, B.J. Sahakian, C.E. Polkey, T.W. Robbins Planning and spatial working memory following frontal-lobe lesions in man Neuropsychologia 28 1990 1021 1034
30. A.M. Owen, R.G. Morris, B.J. Sahakian, C.E. Polkey, T.W. Robbins Double dissociations of memory and executive functions in working memory tasks following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man Brain 119 1996 1597 1615
31. D. Posthuma, E.J.C. De Geus, W.F.C. Baare, H.E.H. Pol, R.S. Kahn, D.I. Boomsma The association between brain volume and intelligence is of genetic origin Nat Neurosci 5 2002 83 84
32. M. Rapoport The cerebellum in psychiatric disorders Int Rev Psychiatry 13 2001 295 301
33. M. Sanfilipo, T. Lafargue, H. Rusinek, L. Arena, C. Loneragan, A Lautin Cognitive performance in schizophrenia Relationship to regional brain volumes and psychiatric symptoms Psychiatry Res 116 2002 1 23
34. K. Schulze, C. McDonald, S. Frangou, P. Sham, A. Grech, T Toulopoulou Hippocampal volume in familial and nonfamilial schizophrenic probands and their unaffected relatives Biol Psychiatry 53 2003 562 570
35. L.J. Seidman, S.V. Faraone, J.M. Goldstein, W.S. Kremen, N.J. Horton, N Makris Left hippocampal volume as a vulnerability indicator for schizophrenia A magnetic resonance imaging morphometric study of nonpsychotic first-degree relatives Arch Gen Psychiatry 59 2002 839 849
36. T. Sharma, E. Lancaster, D. Lee, S. Lewis, T. Sigmundsson, N Takei Brain changes in schizophrenia Volumetric MRI study of families multiply affected with schizophrenia - The Maudsley Family Study 5 Br J Psychiatry 173 1998 132 138
37. W.G. Staal, R. Hijman, H.E.H. Pol, R.S. Kahn Neuropsychological dysfunctions in siblings discordant for schizophrenia Psychiatry Res 95 2000 227 235
38. W.G. Staal, H.E.H. Pol, H.G. Schnack, M.L.C. Hoogendoorn, K. Jellema, R.S. Kahn Structural brain abnormalities in patients with schizophrenia and their healthy siblings Am J Psychiatry 157 2000 416 421
39. U. Tan, M. Tan, P. Polat, Y. Ceylan, S. Suma, A. Okur Magnetic resonance imaging brain size/IQ relations in Turkish university students Intelligence 27 1999 83 92
40. T. Toulopoulou, R.G. Morris, S. Rabe-Hesketh, R.M. Murray Selectivity of verbal memory deficit in schizophrenic patients and their relatives Am J Med Genet 116B 2003 1 7
41. T. Toulopoulou, S. Rabe-Hesketh, H. King, R.M. Murray, R.G. Morris Episodic memory in schizophrenic patients and their relatives Schizophr Res 63 2003 261 271
42. D. Wechsler Wechsler Adult Intelligence Scale-Revised Manual 1981 Psychological Corporation New York
43. D. Wechsler, C.P. Stone Manual for the Wechsler Memory Scale 1945 Psychological Corporation New York
44. D.R. Weinberger Implications of normal brain-development for the pathogenesis of schizophrenia Arch Gen Psychiatry 44 1987 660 669
45. A.P. Weiss, S. Heckers Neuroimaging of declarative memory in schizophrenia Scand J Psychol 42 2001 239 250
46. J.C. Wickett, P.A. Vernon, D.H. Lee Relationships between factors of intelligence and brain volume Pers Individual Differences 29 2000 1095 1122
47. R.L. Williams A note on robust variance estimation for cluster-correlated data Biometrics 56 2000 645 646
48. I.C. Wright, S. Rabe-Hesketh, P.W.R. Woodruff, A.S. David, R.M. Murray, E.T. Bullmore Meta-analysis of regional brain volumes in schizophrenia Am J Psychiatry 157 2000 16 25