메뉴 건너뛰기




Volumn 30, Issue 1, 2011, Pages 97-109

Immunomodulating antibodies and drugs for the treatment of hematological malignancies

Author keywords

Cancer; CpG; Cytokine; Hematological malignancies; Immunomodulation; Immunotherapy; Lenalidomide; Leukemia; Lymphoma; Monoclonal antibodies; Myeloma; Thalidomide

Indexed keywords

ALPHA INTERFERON; ANTINEOPLASTIC AGENT; BLINATUMOMAB; CD134 ANTIGEN; CD137 ANTIGEN; CD27 ANTIGEN; CD40 ANTIGEN; CT 011; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DACETUZUMAB; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 21; IPILIMUMAB; LENALIDOMIDE; LUCATUMUMAB; PROGRAMMED DEATH 1 RECEPTOR; RITUXIMAB; THALIDOMIDE; UNCLASSIFIED DRUG;

EID: 79952283445     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10555-011-9274-3     Document Type: Article
Times cited : (14)

References (120)
  • 1
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • DOI 10.1038/nrc1586
    • W Zou 2005 Immunosuppressive networks in the tumour environment and their therapeutic relevance Nature Reviews. Cancer 5 263 274 15776005 1:CAS:528:DC%2BD2MXivVars7g%3D (Pubitemid 40488632)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.4 , pp. 263-274
    • Zou, W.1
  • 2
    • 7244248664 scopus 로고    scopus 로고
    • From the bench to the bedside: Ways to improve rituximab efficacy
    • DOI 10.1182/blood-2004-03-1110
    • G Cartron H Watier J Golay P Solal-Celigny 2004 From the bench to the bedside: Ways to improve rituximab efficacy Blood 104 2635 2642 15226177 1:CAS:528:DC%2BD2cXpslKjs70%3D (Pubitemid 39434941)
    • (2004) Blood , vol.104 , Issue.9 , pp. 2635-2642
    • Cartron, G.1    Watier, H.2    Golay, J.3    Solal-Celigny, P.4
  • 4
    • 48049118634 scopus 로고    scopus 로고
    • Approved monoclonal antibodies for cancer therapy
    • 18613766 1:CAS:528:DC%2BD1cXos1Chtro%3D
    • M Boyiadzis KA Foon 2008 Approved monoclonal antibodies for cancer therapy Expert Opinion on Biological Therapy 8 1151 1158 18613766 1:CAS:528:DC%2BD1cXos1Chtro%3D
    • (2008) Expert Opinion on Biological Therapy , vol.8 , pp. 1151-1158
    • Boyiadzis, M.1    Foon, K.A.2
  • 5
    • 33846465547 scopus 로고    scopus 로고
    • Immunostimulatory monoclonal antibodies for cancer therapy
    • DOI 10.1038/nrc2051, PII NRC2051
    • I Melero S Hervas-Stubbs M Glennie DM Pardoll L Chen 2007 Immunostimulatory monoclonal antibodies for cancer therapy Nature Reviews. Cancer 7 95 106 17251916 1:CAS:528:DC%2BD2sXotFOjtQ%3D%3D (Pubitemid 46160986)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.2 , pp. 95-106
    • Melero, I.1    Hervas-Stubbs, S.2    Glennie, M.3    Pardoll, D.M.4    Chen, L.5
  • 8
    • 79952124960 scopus 로고    scopus 로고
    • CD137 stimulation enhances the anti-lymphoma activity of anti-CD20 antibodies
    • doi: 10.1182/blood-2010-08-301945
    • Kohrt, H. E., Houot, R., Goldstein, M. J., Weiskopf, K., Alizadeh, A. A., Brody, J., et al. (2010) CD137 stimulation enhances the anti-lymphoma activity of anti-CD20 antibodies. Blood, doi: 10.1182/blood-2010-08-301945.
    • (2010) Blood
    • Kohrt, H.E.1    Houot, R.2    Goldstein, M.J.3    Weiskopf, K.4    Alizadeh, A.A.5    Brody, J.6
  • 10
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: New insights into its biological function and use in tumor immunotherapy
    • DOI 10.1038/ni0702-611
    • JG Egen MS Kuhns JP Allison 2002 CTLA-4: New insights into its biological function and use in tumor immunotherapy Nature Immunology 3 611 618 12087419 1:CAS:528:DC%2BD38Xksl2mtbs%3D (Pubitemid 34752469)
    • (2002) Nature Immunology , vol.3 , Issue.7 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 11
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • 16557261 1:CAS:528:DC%2BD28XivVyru7k%3D
    • W Zou 2006 Regulatory T cells, tumour immunity and immunotherapy Nature Reviews. Immunology 6 295 307 16557261 1:CAS:528:DC%2BD28XivVyru7k%3D
    • (2006) Nature Reviews. Immunology , vol.6 , pp. 295-307
    • Zou, W.1
  • 12
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • 20525992 1:CAS:528:DC%2BC3cXhtVCrtrbN
    • FS Hodi SJ O'Day DF McDermott, et al. 2010 Improved survival with ipilimumab in patients with metastatic melanoma New England Journal of Medicine 363 711 723 20525992 1:CAS:528:DC%2BC3cXhtVCrtrbN
    • (2010) New England Journal of Medicine , vol.363 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 13
    • 2442585121 scopus 로고    scopus 로고
    • Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity
    • L Chen 2004 Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity Nature Reviews. Immunology 4 336 347 15122199 1:CAS:528:DC%2BD2cXjsFChsrY%3D (Pubitemid 38649276)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.5 , pp. 336-347
    • Chen, L.1
  • 15
    • 33745195264 scopus 로고    scopus 로고
    • The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans
    • 16797416 1:CAS:528:DC%2BD28XlvFGru74%3D
    • HR Salih S Wintterle M Krusch, et al. 2006 The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans Experimental Hematology 34 888 894 16797416 1:CAS:528:DC%2BD28XlvFGru74%3D
    • (2006) Experimental Hematology , vol.34 , pp. 888-894
    • Salih, H.R.1    Wintterle, S.2    Krusch, M.3
  • 16
    • 45049087313 scopus 로고    scopus 로고
    • Programmed death 1 is a marker of angioimmunoblastic T-cell lymphoma and B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia
    • 18479731 1:CAS:528:DC%2BD1cXnsF2qu78%3D
    • L Xerri B Chetaille N Seriari, et al. 2008 Programmed death 1 is a marker of angioimmunoblastic T-cell lymphoma and B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia Human Pathology 39 1050 1058 18479731 1:CAS:528:DC%2BD1cXnsF2qu78%3D
    • (2008) Human Pathology , vol.39 , pp. 1050-1058
    • Xerri, L.1    Chetaille, B.2    Seriari, N.3
  • 17
    • 23844439584 scopus 로고    scopus 로고
    • Expression of functional B7-H2 and B7.2 costimulatory molecules and their prognostic implications in de novo acute myeloid leukemia
    • DOI 10.1158/1078-0432.CCR-04-2672
    • H Tamura K Dan K Tamada, et al. 2005 Expression of functional B7-H2 and B7.2 costimulatory molecules and their prognostic implications in de novo acute myeloid leukemia Clinical Cancer Research 11 5708 5717 16115907 1:CAS:528:DC%2BD2MXos1CjsLk%3D (Pubitemid 41170294)
    • (2005) Clinical Cancer Research , vol.11 , Issue.16 , pp. 5708-5717
    • Tamura, H.1    Dan, K.2    Tamada, K.3    Nakamura, K.4    Shioi, Y.5    Hyodo, H.6    Wang, S.-D.7    Dong, H.8    Chen, L.9    Ogata, K.10
  • 18
    • 56149113642 scopus 로고    scopus 로고
    • Clinical significance of B7-H1 (PD-L1) expression in human acute leukemia
    • 1:CAS:528:DC%2BD1cXhtVeisLvI
    • X Chen S Liu L Wang W Zhang Y Ji X Ma 2008 Clinical significance of B7-H1 (PD-L1) expression in human acute leukemia Cancer Biology & Therapy 7 622 627 1:CAS:528:DC%2BD1cXhtVeisLvI
    • (2008) Cancer Biology & Therapy , vol.7 , pp. 622-627
    • Chen, X.1    Liu, S.2    Wang, L.3    Zhang, W.4    Ji, Y.5    Ma, X.6
  • 23
    • 0028073505 scopus 로고
    • A monoclonal antibody against a human B lymphoblastoid cell line induces tumor regression in mice
    • B Hardy I Yampolski R Kovjazin M Galli A Novogrodsky 1994 A monoclonal antibody against a human B lymphoblastoid cell line induces tumor regression in mice Cancer Research 54 5793 5796 7954401 1:CAS:528:DyaK2cXmvFykurk%3D (Pubitemid 24375206)
    • (1994) Cancer Research , vol.54 , Issue.22 , pp. 5793-5796
    • Hardy, B.1    Yampolski, I.2    Kovjazin, R.3    Galli, M.4    Novogrodsky, A.5
  • 24
    • 49649114804 scopus 로고    scopus 로고
    • Phase i safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
    • 18483370 1:CAS:528:DC%2BD1cXmtVCmtbw%3D
    • R Berger R Rotem-Yehudar G Slama, et al. 2008 Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies Clinical Cancer Research 14 3044 3051 18483370 1:CAS:528:DC%2BD1cXmtVCmtbw%3D
    • (2008) Clinical Cancer Research , vol.14 , pp. 3044-3051
    • Berger, R.1    Rotem-Yehudar, R.2    Slama, G.3
  • 25
    • 79952279943 scopus 로고    scopus 로고
    • Phase II safety and efficacy study of CT-011, a humanized anti-PD-1 monoclonal antibody, in combination with rituximab in patients with relapsed follicular lymphoma
    • JR Westin F Chu M Foglietta R Rotem-Yehudar SS Neelapu 2010 Phase II safety and efficacy study of CT-011, a humanized anti-PD-1 monoclonal antibody, in combination with rituximab in patients with relapsed follicular lymphoma Journal of Clinical Oncology 28 15s
    • (2010) Journal of Clinical Oncology , vol.28
    • Westin, J.R.1    Chu, F.2    Foglietta, M.3    Rotem-Yehudar, R.4    Neelapu, S.S.5
  • 26
    • 77954899030 scopus 로고    scopus 로고
    • Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
    • 20516446 1:CAS:528:DC%2BC3cXpslajtLw%3D
    • JR Brahmer CG Drake I Wollner, et al. 2010 Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates Journal of Clinical Oncology 28 19 3167 3175 20516446 1:CAS:528:DC%2BC3cXpslajtLw%3D
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.19 , pp. 3167-3175
    • Brahmer, J.R.1    Drake, C.G.2    Wollner, I.3
  • 27
    • 2542476167 scopus 로고    scopus 로고
    • CD40/CD154 interactions at the interface of tolerance and immunity
    • DOI 10.1146/annurev.immunol.22.012703.104533
    • SA Quezada LZ Jarvinen EF Lind RJ Noelle 2004 CD40/CD154 interactions at the interface of tolerance and immunity Annual Review of Immunology 22 307 328 15032580 1:CAS:528:DC%2BD2cXktlOgs7g%3D (Pubitemid 38680425)
    • (2004) Annual Review of Immunology , vol.22 , pp. 307-328
    • Quezada, S.A.1    Jarvinen, L.Z.2    Lind, E.F.3    Noelle, R.J.4
  • 28
    • 0029075329 scopus 로고
    • Tumor necrosis factor ligand superfamily: Involvement in the pathology of malignant lymphomas
    • 7780126 1:CAS:528:DyaK2MXmtlOmtrs%3D
    • HJ Gruss SK Dower 1995 Tumor necrosis factor ligand superfamily: Involvement in the pathology of malignant lymphomas Blood 85 3378 3404 7780126 1:CAS:528:DyaK2MXmtlOmtrs%3D
    • (1995) Blood , vol.85 , pp. 3378-3404
    • Gruss, H.J.1    Dower, S.K.2
  • 29
    • 0030937548 scopus 로고    scopus 로고
    • CD40/CD40 ligand interactions in normal, reactive and malignant lympho-hematopoietic tissues
    • HJ Gruss F Herrmann V Gattei A Gloghini A Pinto A Carbone 1997 CD40/CD40 ligand interactions in normal, reactive and malignant lympho-hematopoietic tissues Leukaemia & Lymphoma 24 393 422 1:CAS:528:DyaK1MXislCjtbY%3D (Pubitemid 27182198)
    • (1997) Leukemia and Lymphoma , vol.24 , Issue.5-6 , pp. 393-422
    • Gruss, H.-J.1    Herrmann, F.2    Gattei, V.3    Gloghini, A.4    Pinto, A.5    Carbone, A.6
  • 30
    • 0025630628 scopus 로고
    • Temporal association of CD40 antigen expression with discrete stages of human B-cell ontogeny and the efficacy of anti-CD40 immunotoxins against clonogenic B-lineage acute lymphoblastic leukemia as well as B-lineage non-Hodgkin's lymphoma cells
    • 1702326 1:STN:280:DyaK3M%2FptFCrsw%3D%3D
    • FM Uckun K Gajl-Peczalska DE Myers W Jaszcz S Haissig JA Ledbetter 1990 Temporal association of CD40 antigen expression with discrete stages of human B-cell ontogeny and the efficacy of anti-CD40 immunotoxins against clonogenic B-lineage acute lymphoblastic leukemia as well as B-lineage non-Hodgkin's lymphoma cells Blood 76 2449 2456 1702326 1:STN:280:DyaK3M%2FptFCrsw%3D%3D
    • (1990) Blood , vol.76 , pp. 2449-2456
    • Uckun, F.M.1    Gajl-Peczalska, K.2    Myers, D.E.3    Jaszcz, W.4    Haissig, S.5    Ledbetter, J.A.6
  • 31
    • 0029812593 scopus 로고    scopus 로고
    • Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
    • M Cella D Scheidegger K Palmer-Lehmann P Lane A Lanzavecchia G Alber 1996 Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation The Journal of Experimental Medicine 184 747 752 8760829 1:CAS:528:DyaK28XltVCrsbc%3D (Pubitemid 26324129)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.2 , pp. 747-752
    • Cella, M.1    Scheidegger, D.2    Palmer-Lehmann, K.3    Lane, P.4    Lanzavecchia, A.5    Alber, G.6
  • 33
    • 70349334508 scopus 로고    scopus 로고
    • Phase i study of the humanized antiCD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's lymphoma
    • 19636010 1:CAS:528:DC%2BD1MXht1WisbnN
    • R Advani A Forero-Torres RR Furman, et al. 2009 Phase I study of the humanized antiCD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's lymphoma Journal of Clinical Oncology 27 4371 4377 19636010 1:CAS:528:DC%2BD1MXht1WisbnN
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 4371-4377
    • Advani, R.1    Forero-Torres, A.2    Furman, R.R.3
  • 34
    • 76349120845 scopus 로고    scopus 로고
    • A phase i study of dacetuzumab (SGN-40, a humanized anti-CD40 monoclonal antibody) in patients with chronic lymphocytic leukemia
    • 20038235 1:CAS:528:DC%2BC3cXhtlyrtr0%3D
    • RR Furman A Forero-Torres A Shustov JG Drachman 2010 A phase I study of dacetuzumab (SGN-40, a humanized anti-CD40 monoclonal antibody) in patients with chronic lymphocytic leukemia Leukemia and Lymphoma 51 228 235 20038235 1:CAS:528:DC%2BC3cXhtlyrtr0%3D
    • (2010) Leukemia and Lymphoma , vol.51 , pp. 228-235
    • Furman, R.R.1    Forero-Torres, A.2    Shustov, A.3    Drachman, J.G.4
  • 35
    • 77952315198 scopus 로고    scopus 로고
    • A phase i multidose study of dacetuzumab (SGN-40; Humanized anti-CD40 monoclonal antibody) in patients with multiple myeloma
    • 20133895 1:CAS:528:DC%2BC3cXht1yrsbzF
    • M Hussein JR Berenson R Niesvizky, et al. 2010 A phase I multidose study of dacetuzumab (SGN-40; humanized anti-CD40 monoclonal antibody) in patients with multiple myeloma Haematologica 95 845 848 20133895 1:CAS:528: DC%2BC3cXht1yrsbzF
    • (2010) Haematologica , vol.95 , pp. 845-848
    • Hussein, M.1    Berenson, J.R.2    Niesvizky, R.3
  • 36
    • 50949133383 scopus 로고    scopus 로고
    • The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells
    • 18497318 1:CAS:528:DC%2BD1cXpsVaisr0%3D
    • M Luqman S Klabunde K Lin, et al. 2008 The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells Blood 112 711 720 18497318 1:CAS:528:DC%2BD1cXpsVaisr0%3D
    • (2008) Blood , vol.112 , pp. 711-720
    • Luqman, M.1    Klabunde, S.2    Lin, K.3
  • 37
    • 65349169910 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics from a firstin-human phase 1 dose escalation study with antagonist anti-CD40 antibody, HCD122 (formerly CHIR-12.12), in patients with relapsed and refractory Chronic Lymphocytic Leukemia
    • abstract 3575
    • Byrd, J., Flinn, I., Khan, K., et al. (2006). Pharmacokinetics and pharmacodynamics from a firstin-human phase 1 dose escalation study with antagonist anti-CD40 antibody, HCD122 (formerly CHIR-12.12), in patients with relapsed and refractory Chronic Lymphocytic Leukemia. Blood, 108; abstract 3575.
    • (2006) Blood , vol.108
    • Byrd, J.1    Flinn, I.2    Khan, K.3
  • 38
    • 33947688348 scopus 로고    scopus 로고
    • A phase 1 dose escalation study of a fully human, antagonist anti-CD40 antibody, HCD122 (formerly CHIR-12.12), in patients with relapsed and refractory multiple myeloma
    • abstract 3575.
    • Bensinger, W., Jagannath, S., Becker, P., et al. (2006). A phase 1 dose escalation study of a fully human, antagonist anti-CD40 antibody, HCD122 (formerly CHIR-12.12), in patients with relapsed and refractory multiple myeloma. Blood, 108; abstract 3575.
    • (2006) Blood , vol.108
    • Bensinger, W.1    Jagannath, S.2    Becker, P.3
  • 40
    • 77950403194 scopus 로고    scopus 로고
    • CD137 agonist antibody prevents cancer recurrence: Contribution of CD137 on both hematopoietic and non-hematopoietic cells
    • 20068221 1:CAS:528:DC%2BC3cXhtFensbbN
    • H Narazaki Y Zhu L Luo G Zhu L Chen 2010 CD137 agonist antibody prevents cancer recurrence: Contribution of CD137 on both hematopoietic and non-hematopoietic cells Blood 115 10 1941 1948 20068221 1:CAS:528: DC%2BC3cXhtFensbbN
    • (2010) Blood , vol.115 , Issue.10 , pp. 1941-1948
    • Narazaki, H.1    Zhu, Y.2    Luo, L.3    Zhu, G.4    Chen, L.5
  • 41
    • 0032535119 scopus 로고    scopus 로고
    • NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies
    • DOI 10.1006/cimm.1998.1396
    • I Melero JV Johnston WW Shufford RS Mittler L Chen 1998 NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies Cellular Immunology 190 167 172 9878117 1:CAS:528:DyaK1MXhslWhuw%3D%3D (Pubitemid 29011104)
    • (1998) Cellular Immunology , vol.190 , Issue.2 , pp. 167-172
    • Melero, I.1    Johnston, J.V.2    Shufford, W.W.3    Mittler, R.S.4    Chen, L.5
  • 43
    • 55949113750 scopus 로고    scopus 로고
    • Phase i study of BMS-663513, a fully human anti-CD137 agonist monoclonal antibody, in patients (pts) with advanced cancer (CA)
    • 2008 ASCO Annual Meeting
    • Sznol, M., Hodi, F. S., Margolin, K., et al. (2008) Phase I study of BMS-663513, a fully human anti-CD137 agonist monoclonal antibody, in patients (pts) with advanced cancer (CA). J Clin Oncol.;26 (2008 ASCO Annual Meeting).
    • (2008) J Clin Oncol , vol.26
    • Sznol, M.1    Hodi, F.S.2    Margolin, K.3
  • 44
    • 70350713055 scopus 로고    scopus 로고
    • Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion
    • 19641184 1:CAS:528:DC%2BD1MXhtlensb7K
    • R Houot MJ Goldstein HE Kohrt, et al. 2009 Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion Blood 114 3431 3438 19641184 1:CAS:528:DC%2BD1MXhtlensb7K
    • (2009) Blood , vol.114 , pp. 3431-3438
    • Houot, R.1    Goldstein, M.J.2    Kohrt, H.E.3
  • 45
    • 58149232585 scopus 로고    scopus 로고
    • Therapeutic antitumor efficacy of antiCD137 agonistic monoclonal antibody in mouse models of myeloma
    • 18980984 1:CAS:528:DC%2BD1cXhtlens7nJ
    • O Murillo A Arina S Hervas-Stubbs, et al. 2008 Therapeutic antitumor efficacy of antiCD137 agonistic monoclonal antibody in mouse models of myeloma Clinical Cancer Research 14 6895 6906 18980984 1:CAS:528:DC%2BD1cXhtlens7nJ
    • (2008) Clinical Cancer Research , vol.14 , pp. 6895-6906
    • Murillo, O.1    Arina, A.2    Hervas-Stubbs, S.3
  • 46
    • 79952280278 scopus 로고    scopus 로고
    • CD3/CD19 bispecific BiTE antibody blinatumomab treatment of non-Hodgkin lymphoma (NHL) patients: 60 μg/m2/d by continuous infusion is tolerable and results in durable responses
    • M Goebeler A Viardot R Noppeney, et al. 2010 CD3/CD19 bispecific BiTE antibody blinatumomab treatment of non-Hodgkin lymphoma (NHL) patients: 60 μg/m2/d by continuous infusion is tolerable and results in durable responses Heamatologica 95 s2 230
    • (2010) Heamatologica , vol.95 , Issue.S2 , pp. 230
    • Goebeler, M.1    Viardot, A.2    Noppeney, R.3
  • 47
    • 49649120397 scopus 로고    scopus 로고
    • Tumor regression in cancer patients by very low doses of a T cell-engaging antibody
    • 18703743 1:CAS:528:DC%2BD1cXpslWru70%3D
    • R Bargou E Leo G Zugmaier, et al. 2008 Tumor regression in cancer patients by very low doses of a T cell-engaging antibody Science 321 974 977 18703743 1:CAS:528:DC%2BD1cXpslWru70%3D
    • (2008) Science , vol.321 , pp. 974-977
    • Bargou, R.1    Leo, E.2    Zugmaier, G.3
  • 48
    • 79952280660 scopus 로고    scopus 로고
    • Report of a phase II trial of single-agent BiTE® antibody Blinatumomab in patients with minimal residual disease (MRD) positive Bprecursor acute lymphoblastic leukemia (ALL)
    • abstract 840
    • Topp, M. S., Zugmaier, G., Goekbuget, N., et al. (2009). Report of a phase II trial of single-agent BiTE® antibody Blinatumomab in patients with minimal residual disease (MRD) positive Bprecursor acute lymphoblastic leukemia (ALL). Blood, 114: abstract 840.
    • (2009) Blood , vol.114
    • Topp, M.S.1    Zugmaier, G.2    Goekbuget, N.3
  • 49
    • 33748683549 scopus 로고    scopus 로고
    • Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma
    • DOI 10.1097/01.cji.0000211304.60126.8f, PII 0000237120060900000010
    • BK Link ZK Ballas D Weisdorf, et al. 2006 Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma Journal of Immunotherapy 29 558 568 16971811 1:CAS:528:DC%2BD28XpsVantb8%3D (Pubitemid 44395280)
    • (2006) Journal of Immunotherapy , vol.29 , Issue.5 , pp. 558-568
    • Link, B.K.1    Ballas, Z.K.2    Weisdorf, D.3    Wooldridge, J.E.4    Bossler, A.D.5    Shannon, M.6    Rasmussen, W.L.7    Krieg, A.M.8    Weiner, G.J.9
  • 50
    • 0034141541 scopus 로고    scopus 로고
    • Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells
    • T Decker F Schneller T Sparwasser, et al. 2000 Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells Blood 95 999 1006 10648415 1:CAS:528:DC%2BD3cXotV2guw%3D%3D (Pubitemid 30062724)
    • (2000) Blood , vol.95 , Issue.3 , pp. 999-1006
    • Decker, T.1    Schneller, F.2    Sparwasser, T.3    Tretter, T.4    Lipford, G.B.5    Wagner, H.6    Peschel, C.7
  • 52
    • 37249026830 scopus 로고    scopus 로고
    • NK cells stimulated with IL-15 or CpG ODN enhance rituximab-dependent cellular cytotoxicity against B-cell lymphoma
    • DOI 10.1016/j.exphem.2007.08.012, PII S0301472X07005206
    • E Moga E Alvarez E Canto, et al. 2008 NK cells stimulated with IL-15 or CpG ODN enhance rituximab-dependent cellular cytotoxicity against B-cell lymphoma Experimental Hematology 36 69 77 17959301 1:CAS:528:DC%2BD2sXhsVOrtrzI (Pubitemid 350266964)
    • (2008) Experimental Hematology , vol.36 , Issue.1 , pp. 69-77
    • Moga, E.1    Alvarez, E.2    Canto, E.3    Vidal, S.4    Rodriguez-Sanchez, J.L.5    Sierra, J.6    Briones, J.7
  • 53
    • 11244280803 scopus 로고    scopus 로고
    • Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: Increased interferon-α/ β-inducible gene expression, without significant toxicity
    • DOI 10.1182/blood-2004-06-2156
    • JW Friedberg H Kim M McCauley, et al. 2005 Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: Increased interferon-alpha/beta-inducible gene expression, without significant toxicity Blood 105 489 495 15358617 1:CAS:528:DC%2BD2MXltlGisg%3D%3D (Pubitemid 40070726)
    • (2005) Blood , vol.105 , Issue.2 , pp. 489-495
    • Friedberg, J.W.1    Kim, H.2    McCauley, M.3    Hessel, E.M.4    Sims, P.5    Fisher, D.C.6    Nadler, L.M.7    Coffman, R.L.8    Freedman, A.S.9
  • 55
    • 67650487106 scopus 로고    scopus 로고
    • Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma
    • 1:CAS:528:DC%2BD1MXhtValurrL
    • JW Friedberg JL Kelly D Neuberg, et al. 2009 Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma British Journal Haematology 146 282 291 1:CAS:528: DC%2BD1MXhtValurrL
    • (2009) British Journal Haematology , vol.146 , pp. 282-291
    • Friedberg, J.W.1    Kelly, J.L.2    Neuberg, D.3
  • 56
    • 78049420571 scopus 로고    scopus 로고
    • In situ vaccination with a TLR9 agonist induces systemic lymphoma regression: A phase I/II Study
    • 20697067
    • JD Brody WZ Ai DK Czerwinski, et al. 2010 In situ vaccination with a TLR9 agonist induces systemic lymphoma regression: A phase I/II Study Journal of Clinical Oncology 28 28 4324 4332 20697067
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.28 , pp. 4324-4332
    • Brody, J.D.1    Ai, W.Z.2    Czerwinski, D.K.3
  • 57
    • 34848856815 scopus 로고    scopus 로고
    • Lymphoma immunotherapy with CpG oligodeoxynucleotides requires TLR9 either in the host or in the tumor itself
    • 1:CAS:528:DC%2BD2sXosVyqsb4%3D
    • J Li W Song DK Czerwinski, et al. 2007 Lymphoma immunotherapy with CpG oligodeoxynucleotides requires TLR9 either in the host or in the tumor itself Journal of Immunology 179 2493 2500 1:CAS:528:DC%2BD2sXosVyqsb4%3D
    • (2007) Journal of Immunology , vol.179 , pp. 2493-2500
    • Li, J.1    Song, W.2    Czerwinski, D.K.3
  • 58
    • 0032748385 scopus 로고    scopus 로고
    • Antitumor activity of thalidomide in refractory multiple myeloma
    • 10564685 1:CAS:528:DyaK1MXotVSgs78%3D
    • S Singhal J Mehta R Desikan, et al. 1999 Antitumor activity of thalidomide in refractory multiple myeloma The New England Journal of Medicine 341 1565 1571 10564685 1:CAS:528:DyaK1MXotVSgs78%3D
    • (1999) The New England Journal of Medicine , vol.341 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 61
    • 38949106198 scopus 로고    scopus 로고
    • Thalidomide has limited single-agent activity in relapsed or refractory indolent non-Hodgkin lymphomas: A phase II trial of the Cancer and Leukemia Group B
    • DOI 10.1111/j.1365-2141.2007.06937.x
    • SM Smith D Grinblatt JL Johnson, et al. 2008 Thalidomide has limited single-agent activity in relapsed or refractory indolent non-Hodgkin lymphomas: A phase II trial of the cancer and leukemia group B British Journal Haematology 140 313 319 1:CAS:528:DC%2BD1cXitlakt7s%3D (Pubitemid 351209487)
    • (2008) British Journal of Haematology , vol.140 , Issue.3 , pp. 313-319
    • Smith, S.M.1    Grinblatt, D.2    Johnson, J.L.3    Niedzwiecki, D.4    Rizzieri, D.5    Bartlett, N.L.6    Cheson, B.D.7
  • 62
    • 4944229959 scopus 로고    scopus 로고
    • Antitumor activity of rituximab plus thalidomide in patients with relapsed/refractory mantle cell lymphoma
    • DOI 10.1182/blood-2004-03-1091
    • H Kaufmann M Raderer S Wohrer, et al. 2004 Antitumor activity of rituximab plus thalidomide in patients with relapsed/refractory mantle cell lymphoma Blood 104 2269 2271 15166030 1:CAS:528:DC%2BD2cXovVegtr4%3D (Pubitemid 39331822)
    • (2004) Blood , vol.104 , Issue.8 , pp. 2269-2271
    • Kaufmann, H.1    Raderer, M.2    Wohrer, S.3    Puspok, A.4    Bankier, A.5    Zielinski, C.6    Chott, A.7    Drach, J.8
  • 63
    • 57649198069 scopus 로고    scopus 로고
    • Thalidomide and rituximab in Waldenstrom macroglobulinemia
    • 18713945 1:CAS:528:DC%2BD1cXhsVCltb3N
    • SP Treon JD Soumerai AR Branagan, et al. 2008 Thalidomide and rituximab in Waldenstrom macroglobulinemia Blood 112 4452 4457 18713945 1:CAS:528:DC%2BD1cXhsVCltb3N
    • (2008) Blood , vol.112 , pp. 4452-4457
    • Treon, S.P.1    Soumerai, J.D.2    Branagan, A.R.3
  • 65
    • 45949100928 scopus 로고    scopus 로고
    • Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia
    • 18334676 1:CAS:528:DC%2BD1cXntFWnsr4%3D
    • A Ferrajoli BN Lee EJ Schlette, et al. 2008 Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia Blood 111 5291 5297 18334676 1:CAS:528:DC%2BD1cXntFWnsr4%3D
    • (2008) Blood , vol.111 , pp. 5291-5297
    • Ferrajoli, A.1    Lee, B.N.2    Schlette, E.J.3
  • 67
    • 70149117963 scopus 로고    scopus 로고
    • Treatment of hematologic neoplasms with new immunomodulatory drugs (IMiDs)
    • 19016330
    • PH Wiernik 2009 Treatment of hematologic neoplasms with new immunomodulatory drugs (IMiDs) Current Treatment Options in Oncology 10 1 15 19016330
    • (2009) Current Treatment Options in Oncology , vol.10 , pp. 1-15
    • Wiernik, P.H.1
  • 68
    • 73949145763 scopus 로고    scopus 로고
    • Lenalidomide oral monotherapy produces durable responses in relapsed or refractory indolent non-Hodgkin's lymphoma
    • 19805688 1:CAS:528:DC%2BD1MXhsFKkt7vN
    • TE Witzig PH Wiernik T Moore, et al. 2009 Lenalidomide oral monotherapy produces durable responses in relapsed or refractory indolent non-Hodgkin's lymphoma Journal of Clinical Oncology 27 5404 5409 19805688 1:CAS:528: DC%2BD1MXhsFKkt7vN
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 5404-5409
    • Witzig, T.E.1    Wiernik, P.H.2    Moore, T.3
  • 69
    • 64149112784 scopus 로고    scopus 로고
    • Lenalidomide oral monotherapy produces a high response rate in patients with relapsed or refractory mantle cell lymphoma
    • 1:CAS:528:DC%2BD1MXlslOhsrc%3D
    • TM Habermann IS Lossos G Justice, et al. 2009 Lenalidomide oral monotherapy produces a high response rate in patients with relapsed or refractory mantle cell lymphoma British Journal Haematology 145 344 349 1:CAS:528:DC%2BD1MXlslOhsrc%3D
    • (2009) British Journal Haematology , vol.145 , pp. 344-349
    • Habermann, T.M.1    Lossos, I.S.2    Justice, G.3
  • 70
    • 39849099704 scopus 로고    scopus 로고
    • An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndrome
    • 18271621
    • BL Ebert N Galili P Tamayo, et al. 2008 An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndrome PLoS Medicine 5 e35 18271621
    • (2008) PLoS Medicine , vol.5 , pp. 35
    • Ebert, B.L.1    Galili, N.2    Tamayo, P.3
  • 71
    • 45149115902 scopus 로고    scopus 로고
    • Higher doses of lenalidomide are associated with unacceptable toxicity including life-threatening tumor flare in patients with chronic lymphocytic leukemia
    • 18427150 1:CAS:528:DC%2BD1cXnsVKhurg%3D
    • LA Andritsos AJ Johnson G Lozanski, et al. 2008 Higher doses of lenalidomide are associated with unacceptable toxicity including life-threatening tumor flare in patients with chronic lymphocytic leukemia Journal of Clinical Oncology 26 2519 2525 18427150 1:CAS:528: DC%2BD1cXnsVKhurg%3D
    • (2008) Journal of Clinical Oncology , vol.26 , pp. 2519-2525
    • Andritsos, L.A.1    Johnson, A.J.2    Lozanski, G.3
  • 72
    • 74049104854 scopus 로고    scopus 로고
    • Lenalidomide in patients with refractory or multiple relapsed Hodgkin lymphoma
    • 19863533
    • B Boll P Borchmann MS Topp, et al. 2010 Lenalidomide in patients with refractory or multiple relapsed Hodgkin lymphoma British Journal of Haematology 148 480 482 19863533
    • (2010) British Journal of Haematology , vol.148 , pp. 480-482
    • Boll, B.1    Borchmann, P.2    Topp, M.S.3
  • 73
    • 74049139971 scopus 로고    scopus 로고
    • Tumor flare reactions and response to lenalidomide in patients with refractory classic Hodgkin lymphoma
    • G Corazzelli R De Filippi G Capobianco, et al. 2009 Tumor flare reactions and response to lenalidomide in patients with refractory classic Hodgkin lymphoma American Journal of Hematology 85 87 90
    • (2009) American Journal of Hematology , vol.85 , pp. 87-90
    • Corazzelli, G.1    De Filippi, R.2    Capobianco, G.3
  • 74
    • 77957566161 scopus 로고    scopus 로고
    • Interim report of a phase 2 clinical trial of lenalidomide for T-cell non-Hodgkin lymphoma
    • 20572046 1:CAS:528:DC%2BC3cXht1KnsLrJ
    • G Dueck N Chua A Prasad, et al. 2010 Interim report of a phase 2 clinical trial of lenalidomide for T-cell non-Hodgkin lymphoma Cancer 116 19 4541 4548 20572046 1:CAS:528:DC%2BC3cXht1KnsLrJ
    • (2010) Cancer , vol.116 , Issue.19 , pp. 4541-4548
    • Dueck, G.1    Chua, N.2    Prasad, A.3
  • 75
    • 51649123319 scopus 로고    scopus 로고
    • Lenalidomide enhances natural killer cell and monocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20+ tumor cells
    • 18628480 1:CAS:528:DC%2BD1cXosFGiur8%3D
    • L Wu M Adams T Carter, et al. 2008 lenalidomide enhances natural killer cell and monocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20+ tumor cells Clinical Cancer Research 14 4650 4657 18628480 1:CAS:528:DC%2BD1cXosFGiur8%3D
    • (2008) Clinical Cancer Research , vol.14 , pp. 4650-4657
    • Wu, L.1    Adams, M.2    Carter, T.3
  • 76
    • 58149399362 scopus 로고    scopus 로고
    • Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells
    • 18772452 1:CAS:528:DC%2BD1cXhsFWms7vI
    • R Lapalombella B Yu G Triantafillou, et al. 2008 Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells Blood 112 5180 5189 18772452 1:CAS:528:DC%2BD1cXhsFWms7vI
    • (2008) Blood , vol.112 , pp. 5180-5189
    • Lapalombella, R.1    Yu, B.2    Triantafillou, G.3
  • 77
    • 23844435619 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model
    • FJ Hernandez-Ilizaliturri N Reddy B Holkova E Ottman MS Czuczman 2005 Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model Clinical Cancer Research 11 59845992
    • (2005) Clinical Cancer Research , vol.11 , pp. 59845992
    • Hernandez-Ilizaliturri, F.J.1    Reddy, N.2    Holkova, B.3    Ottman, E.4    Czuczman, M.S.5
  • 78
    • 58849160495 scopus 로고    scopus 로고
    • Lenalidomide and rituximab in Waldenstrom's macroglobulinemia
    • 19118065 1:CAS:528:DC%2BD1MXhs1eqtw%3D%3D
    • SP Treon JD Soumerai AR Branagan, et al. 2009 Lenalidomide and rituximab in Waldenstrom's macroglobulinemia Clinical Cancer Research 15 355 360 19118065 1:CAS:528:DC%2BD1MXhs1eqtw%3D%3D
    • (2009) Clinical Cancer Research , vol.15 , pp. 355-360
    • Treon, S.P.1    Soumerai, J.D.2    Branagan, A.R.3
  • 79
    • 77953658094 scopus 로고    scopus 로고
    • A Phase I/II study of lenalidomide in combination with rituximab in relapsed/refractory mantle cell lymphoma
    • Abstr 2719
    • Wang, L., Fayad, L., Hagemeister, F. B., et al. (2009). A Phase I/II study of lenalidomide in combination with rituximab in relapsed/refractory mantle cell lymphoma. ASH meeting, Abstr 2719.
    • (2009) ASH Meeting
    • Wang, L.1    Fayad, L.2    Hagemeister, F.B.3
  • 80
    • 79952281098 scopus 로고    scopus 로고
    • Analysis of a phase 2 study of lenalidomide and rituximab in relapsed or refractory non-Hodgkin's lymphoma
    • abst # 0295
    • Dutia, M., DeRoock, I., Chee, K., et al. (2010). Analysis of a phase 2 study of lenalidomide and rituximab in relapsed or refractory non-Hodgkin's lymphoma. EHA meeting, abst # 0295.
    • (2010) EHA Meeting
    • Dutia, M.1    Deroock, I.2    Chee, K.3
  • 81
    • 79952853727 scopus 로고    scopus 로고
    • Complete response rates with lenalidomide plus rituximab for untreated indolent B-cell non-hodgkin's lymphoma
    • NH Fowler P McLaughlin FB Hagemeister, et al. 2010 Complete response rates with lenalidomide plus rituximab for untreated indolent B-cell non-hodgkin's lymphoma Journal of Clinical Oncology 28 15s
    • (2010) Journal of Clinical Oncology , vol.28
    • Fowler, N.H.1    McLaughlin, P.2    Hagemeister, F.B.3
  • 82
    • 0037251878 scopus 로고    scopus 로고
    • Rituximab: A review of its use in non-Hodgkin's lymphoma and chronic lymphocytic leukaemia
    • DOI 10.2165/00003495-200363080-00005
    • GL Plosker DP Figgitt 2003 Rituximab: A review of its use in non-Hodgkin's lymphoma and chronic lymphocytic leukaemia Drugs 63 803 843 12662126 1:CAS:528:DC%2BD3sXjsF2gtbw%3D (Pubitemid 36432084)
    • (2003) Drugs , vol.63 , Issue.8 , pp. 803-843
    • Plosker, G.L.1    Figgitt, D.P.2
  • 84
    • 0023115642 scopus 로고
    • A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone
    • SA Rosenberg MT Lotze LM Muul, et al. 1987 A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone The New England Journal of Medicine 316 889 897 3493432 1:STN:280:DyaL2s7ksVGitA%3D%3D (Pubitemid 17041979)
    • (1987) New England Journal of Medicine , vol.316 , Issue.15 , pp. 889-897
    • Rosenberg, S.A.1    Lotze, M.T.2    Muul, L.M.3
  • 89
    • 0028987027 scopus 로고
    • Interleukin 12: A new clinical player in cytokine therapy
    • 7710924 1:CAS:528:DyaK2MXmtF2ks7c%3D
    • RE Banks PM Patel PJ Selby 1995 Interleukin 12: A new clinical player in cytokine therapy British Journal of Cancer 71 655 659 7710924 1:CAS:528:DyaK2MXmtF2ks7c%3D
    • (1995) British Journal of Cancer , vol.71 , pp. 655-659
    • Banks, R.E.1    Patel, P.M.2    Selby, P.J.3
  • 92
    • 52949129439 scopus 로고    scopus 로고
    • Interleukin-21: Biology and application to cancer therapy
    • 18694350 1:CAS:528:DC%2BD1cXpslart7o%3D
    • DJ Andorsky JM Timmerman 2008 Interleukin-21: Biology and application to cancer therapy Expert Opinion on Biological Therapy 8 1295 1307 18694350 1:CAS:528:DC%2BD1cXpslart7o%3D
    • (2008) Expert Opinion on Biological Therapy , vol.8 , pp. 1295-1307
    • Andorsky, D.J.1    Timmerman, J.M.2
  • 93
    • 35948961556 scopus 로고    scopus 로고
    • The activation of natural killer cell effector functions by cetuximab-coated, epidermal growth factor receptor - Positive tumor cells is enhanced by cytokines
    • DOI 10.1158/1078-0432.CCR-07-0865
    • JM Roda T Joshi JP Butchar, et al. 2007 The activation of natural killer cell effector functions by cetuximab-coated, epidermal growth factor receptor positive tumor cells is enhanced by cytokines Clinical Cancer Research 13 6419 6428 17962339 1:CAS:528:DC%2BD2sXht1CgtbzI (Pubitemid 350075032)
    • (2007) Clinical Cancer Research , vol.13 , Issue.21 , pp. 6419-6428
    • Roda, J.M.1    Joshi, T.2    Butchar, J.P.3    McAlees, J.W.4    Lehman, A.5    Tridandapani, S.6    Carson III, W.E.7
  • 96
  • 97
    • 38549100096 scopus 로고    scopus 로고
    • Long-term molecular remissions in patients with indolent lymphoma treated with rituximab as a single agent or in combination with interferon alpha-2a: A randomized phase II study from the Nordic Lymphoma Group
    • DOI 10.1080/10428190701704647, PII 789687799
    • E Kimby J Jurlander C Geisler, et al. 2008 Long-term molecular remissions in patients with indolent lymphoma treated with rituximab as a single agent or in combination with interferon alpha-2a: A randomized phase II study from the Nordic Lymphoma Group Leukaemia & Lymphoma 49 102 112 1:CAS:528: DC%2BD1cXnsFequw%3D%3D (Pubitemid 351146889)
    • (2008) Leukemia and Lymphoma , vol.49 , Issue.1 , pp. 102-112
    • Kimby, E.1    Jurlander, J.2    Geisler, C.3    Hagberg, H.4    Holte, H.5    Lehtinen, T.6    Ostenstad, B.7    Hansen, M.8    Osterborg, A.9    Linden, O.10    Sundstrom, C.11
  • 98
    • 0043028655 scopus 로고    scopus 로고
    • Treatment of relapsed B-cell non-Hodgkin's lymphoma with a combination of chimeric anti-CD20 monoclonal antibodies (rituximab) and G-CSF: Final report on safety and efficacy
    • DOI 10.1038/sj.leu.2402995
    • LE van der Kolk AJ Grillo-Lopez JW Baars MH van Oers 2003 Treatment of relapsed Bcell non-Hodgkin's lymphoma with a combination of chimeric anti-CD20 monoclonal antibodies (rituximab) and G-CSF: Final report on safety and efficacy Leukemia 17 1658 1664 12886256 (Pubitemid 36986970)
    • (2003) Leukemia , vol.17 , Issue.8 , pp. 1658-1664
    • Van Der Kolk, L.E.1    Grillo-Lopez, A.J.2    Baars, J.W.3    Van Oers, M.H.J.4
  • 99
    • 45749104147 scopus 로고    scopus 로고
    • Granulocyte-macrophage colonystimulating factor potentiates rituximab in patients with relapsed follicular lymphoma: Results of a phase II study
    • 18427151 1:CAS:528:DC%2BD1cXnvVOhsbk%3D
    • G Cartron L Zhao-Yang M Baudard, et al. 2008 Granulocyte-macrophage colonystimulating factor potentiates rituximab in patients with relapsed follicular lymphoma: Results of a phase II study Journal of Clinical Oncology 26 2725 2731 18427151 1:CAS:528:DC%2BD1cXnvVOhsbk%3D
    • (2008) Journal of Clinical Oncology , vol.26 , pp. 2725-2731
    • Cartron, G.1    Zhao-Yang, L.2    Baudard, M.3
  • 100
    • 0038811776 scopus 로고    scopus 로고
    • Single-agent rituximab as first-line and maintenance treatment for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma: A phase II trial of the Minnie Pearl Cancer Research Network
    • DOI 10.1200/JCO.2003.09.027
    • JD Hainsworth S Litchy JH Barton, et al. 2003 Single-agent rituximab as first-line and maintenance treatment for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma: A phase II trial of the Minnie Pearl Cancer Research Network Journal of Clinical Oncology 21 1746 1751 12721250 1:CAS:528:DC%2BD2cXpsVWqtr8%3D (Pubitemid 46638587)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.9 , pp. 1746-1751
    • Hainsworth, J.D.1    Litchy, S.2    Barton, J.H.3    Houston, G.A.4    Hermann, R.C.5    Bradof, J.E.6    Greco, F.A.7
  • 101
    • 0035469851 scopus 로고    scopus 로고
    • Rituximab therapy of patients with B-cell chronic lymphocytic leukemia
    • 11520778 1:CAS:528:DC%2BD3MXmvFGjtro%3D
    • D Huhn C von Schilling M Wilhelm, et al. 2001 Rituximab therapy of patients with B-cell chronic lymphocytic leukemia Blood 98 1326 1331 11520778 1:CAS:528:DC%2BD3MXmvFGjtro%3D
    • (2001) Blood , vol.98 , pp. 1326-1331
    • Huhn, D.1    Von Schilling, C.2    Wilhelm, M.3
  • 102
    • 0036757311 scopus 로고    scopus 로고
    • Standard-dose anti-CD20 antibody rituximab has efficacy in chronic lymphocytic leukaemia: Results from a nordic multicentre study
    • DOI 10.1034/j.1600-0609.2002.02786.x
    • M Itala CH Geisler E Kimby, et al. 2002 Standard-dose anti-CD20 antibody rituximab has efficacy in chronic lymphocytic leukaemia: Results from a Nordic multicentre study European Journal of Haematology 69 129 134 12406005 1:CAS:528:DC%2BD38XpsVWgs7k%3D (Pubitemid 35335149)
    • (2002) European Journal of Haematology , vol.69 , Issue.3 , pp. 129-134
    • Itala, M.1    Geisler, Ch.2    Kimby, E.3    Juvonen, E.4    Tjonnfjord, G.5    Karlsson, K.6    Remes, K.7
  • 103
    • 51449109938 scopus 로고    scopus 로고
    • Rituximab plus GM-CSF (Leukine) for indolent lymphoma. Proceedings of the 9th International Conference on Malignant lymphomas
    • P McLaughlin N Liu N Poindexter, et al. 2005 Rituximab plus GM-CSF (Leukine) for indolent lymphoma. Proceedings of the 9th International Conference on Malignant lymphomas Annals of Oncology 16 v68
    • (2005) Annals of Oncology , vol.16 , pp. 68
    • McLaughlin, P.1    Liu, N.2    Poindexter, N.3
  • 104
    • 0034306979 scopus 로고    scopus 로고
    • Therapeutic efficacy of OX-40 receptor antibody depends on tumor immunogenicity and anatomic site of tumor growth
    • 11034096 1:CAS:528:DC%2BD3cXns1eht78%3D
    • J Kjaergaard J Tanaka JA Kim K Rothchild A Weinberg S Shu 2000 Therapeutic efficacy of OX-40 receptor antibody depends on tumor immunogenicity and anatomic site of tumor growth Cancer Research 60 5514 5521 11034096 1:CAS:528:DC%2BD3cXns1eht78%3D
    • (2000) Cancer Research , vol.60 , pp. 5514-5521
    • Kjaergaard, J.1    Tanaka, J.2    Kim, J.A.3    Rothchild, K.4    Weinberg, A.5    Shu, S.6
  • 105
    • 42249097689 scopus 로고    scopus 로고
    • OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection
    • DOI 10.1084/jem.20071341
    • S Piconese B Valzasina MP Colombo 2008 OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection The Journal of Experimental Medicine 205 825 839 18362171 1:CAS:528:DC%2BD1cXkvVyrsrg%3D (Pubitemid 351549881)
    • (2008) Journal of Experimental Medicine , vol.205 , Issue.4 , pp. 825-839
    • Piconese, S.1    Valzasina, B.2    Colombo, M.P.3
  • 108
    • 34249722182 scopus 로고    scopus 로고
    • Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal antibody therapy is critically dependent on CD27 costimulation
    • DOI 10.1182/blood-2006-11-057216
    • RR French VY Taraban GR Crowther, et al. 2007 Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal antibody therapy is critically dependent on CD27 costimulation Blood 109 4810 4815 17311995 1:CAS:528:DC%2BD2sXmt1Ogur0%3D (Pubitemid 46827776)
    • (2007) Blood , vol.109 , Issue.11 , pp. 4810-4815
    • French, R.R.1    Taraban, V.Y.2    Crowther, G.R.3    Rowley, T.F.4    Gray, J.C.5    Johnson, P.W.6    Tutt, A.L.7    Al-Shamkhani, A.8    Glennie, M.J.9
  • 109
    • 77949485107 scopus 로고    scopus 로고
    • Anti-tumor effects of depleting and non-depleting anti-CD27 monoclonal antibodies in immune-competent mice
    • 20171165 1:CAS:528:DC%2BC3cXjs1Ontbc%3D
    • T Sakanishi H Yagita 2010 Anti-tumor effects of depleting and non-depleting anti-CD27 monoclonal antibodies in immune-competent mice Biochemical and Biophysical Research Communications 393 829 835 20171165 1:CAS:528:DC%2BC3cXjs1Ontbc%3D
    • (2010) Biochemical and Biophysical Research Communications , vol.393 , pp. 829-835
    • Sakanishi, T.1    Yagita, H.2
  • 111
    • 0029947568 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by CTLA-4 blockade
    • DR Leach MF Krummel JP Allison 1996 Enhancement of antitumor immunity by CTLA-4 blockade Science 271 1734 1736 8596936 1:CAS:528:DyaK28XhvVWmsLk%3D (Pubitemid 26102823)
    • (1996) Science , vol.271 , Issue.5256 , pp. 1734-1736
    • Leach, D.R.1    Krummel, M.F.2    Allison, J.P.3
  • 113
    • 0032896709 scopus 로고    scopus 로고
    • CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help
    • DOI 10.1038/8426
    • RR French HT Chan AL Tutt MJ Glennie 1999 CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help Natural Medicines 5 548 553 1:CAS:528:DyaK1MXivVKrs7g%3D (Pubitemid 29220214)
    • (1999) Nature Medicine , vol.5 , Issue.5 , pp. 548-553
    • French, R.R.1    Chan, H.T.C.2    Tutt, A.L.3    Glennie, M.J.4
  • 115
    • 69249108787 scopus 로고    scopus 로고
    • Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells
    • 19553639 1:CAS:528:DC%2BD1MXht1eit7vL
    • F Romagne P Andre P Spee, et al. 2009 Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells Blood 114 2667 2677 19553639 1:CAS:528:DC%2BD1MXht1eit7vL
    • (2009) Blood , vol.114 , pp. 2667-2677
    • Romagne, F.1    Andre, P.2    Spee, P.3
  • 117
    • 61849165013 scopus 로고    scopus 로고
    • CTLA4 blockade with ipilimumab to treat relapse of malignancy after allogeneic hematopoietic cell transplantation
    • 18974373 1:CAS:528:DC%2BD1MXitlCrtbk%3D
    • A Bashey B Medina S Corringham, et al. 2009 CTLA4 blockade with ipilimumab to treat relapse of malignancy after allogeneic hematopoietic cell transplantation Blood 113 1581 1588 18974373 1:CAS:528:DC%2BD1MXitlCrtbk%3D
    • (2009) Blood , vol.113 , pp. 1581-1588
    • Bashey, A.1    Medina, B.2    Corringham, S.3
  • 118
    • 70350244852 scopus 로고    scopus 로고
    • Phase i study of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with relapsed and refractory B-cell non-Hodgkin lymphoma
    • 19808874 1:CAS:528:DC%2BD1MXhtlyqsbzN
    • SM Ansell SA Hurvitz PA Koenig, et al. 2009 Phase I study of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with relapsed and refractory B-cell non-Hodgkin lymphoma Clinical Cancer Research 15 6446 6453 19808874 1:CAS:528:DC%2BD1MXhtlyqsbzN
    • (2009) Clinical Cancer Research , vol.15 , pp. 6446-6453
    • Ansell, S.M.1    Hurvitz, S.A.2    Koenig, P.A.3
  • 119
    • 0036090166 scopus 로고    scopus 로고
    • Phase 1 study of interleukin-12 in combination with rituximab in patients with B-cell non-Hodgkin lymphoma
    • 11756154 1:CAS:528:DC%2BD38XivF2jtA%3D%3D
    • SM Ansell TE Witzig PJ Kurtin, et al. 2002 Phase 1 study of interleukin-12 in combination with rituximab in patients with B-cell non-Hodgkin lymphoma Blood 99 67 74 11756154 1:CAS:528:DC%2BD38XivF2jtA%3D%3D
    • (2002) Blood , vol.99 , pp. 67-74
    • Ansell, S.M.1    Witzig, T.E.2    Kurtin, P.J.3
  • 120
    • 67650879316 scopus 로고    scopus 로고
    • Incorporating the use of GM-CSF in the treatment of chronic lymphocytic leukemia
    • 1:CAS:528:DC%2BD1MXktVKisbY%3D
    • A Ferrajoli 2009 Incorporating the use of GM-CSF in the treatment of chronic lymphocytic leukemia Leukaemia & Lymphoma 50 514 516 1:CAS:528:DC%2BD1MXktVKisbY%3D
    • (2009) Leukaemia & Lymphoma , vol.50 , pp. 514-516
    • Ferrajoli, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.