메뉴 건너뛰기




Volumn 10, Issue 1-2, 2009, Pages 1-15

Treatment of hematologic neoplasms with new immunomodulatory drugs (IMiDs)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALLOPURINOL; ANTINEOPLASTIC AGENT; BORTEZOMIB; CLADRIBINE; CLARITHROMYCIN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DEXAMETHASONE; ERYTHROPOIETIN; FLUDARABINE; GLUCOCORTICOID; IMMUNOMODULATING AGENT; LENALIDOMIDE; LOW MOLECULAR WEIGHT HEPARIN; MELPHALAN; OSTEONECTIN; PLACEBO; POMALIDOMIDE; PREDNISONE; RITUXIMAB; SUNITINIB; THALIDOMIDE; THALIDOMIDE DERIVATIVE;

EID: 70149117963     PISSN: 15272729     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11864-008-0077-x     Document Type: Review
Times cited : (10)

References (102)
  • 1
    • 47649085380 scopus 로고    scopus 로고
    • Thalidomide and lenalidomide: Mechanism-based potential drug combinations
    • doi: 10.1080/10428190802005191
    • Vallet S, Palumbo A, Raje N, Boccadoro M, Anderson KC: Thalidomide and lenalidomide: Mechanism-based potential drug combinations. Leuk Lymphoma 49:1238-1245, 2008. doi: 10.1080/10428190802005191
    • (2008) Leuk Lymphoma , vol.49 , pp. 1238-1245
    • Vallet, S.1    Palumbo, A.2    Raje, N.3    Boccadoro, M.4    Anderson, K.C.5
  • 3
    • 42549163458 scopus 로고    scopus 로고
    • Thalidomide: Mechanisms of action
    • doi: 10.1080/08830180801911339
    • ParavarMT, Lee DJ: Thalidomide: mechanisms of action. Int Rev Immunol 27:111-135, 2008. doi: 10.1080/08830180801911339
    • (2008) Int Rev Immunol , vol.27 , pp. 111-135
    • Paravar, T.1    Lee, D.J.2
  • 5
    • 52549088421 scopus 로고    scopus 로고
    • Immunomodulatory drugs Revlamid® (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation
    • Zhu D, Corral LG, Fleming YW, et al.: Immunomodulatory drugs Revlamid® (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation. Cancer Immunol Immunother, 2008, 57: 1849-1851
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1849-1851
    • Zhu, D.1    Corral, L.G.2    Fleming, Y.W.3
  • 6
    • 60449115552 scopus 로고    scopus 로고
    • The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions
    • in press
    • Lu L, Payvandi F, Wu L, et al.: The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions. Microvasc Res, in press, 2008
    • (2008) Microvasc Res
    • Lu, L.1    Payvandi, F.2    Wu, L.3
  • 7
    • 51649123319 scopus 로고    scopus 로고
    • Lenalidomide enhances natural killer cells and monocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20+ tumor cells
    • doi: 10.1158/1078-0432.CCR-07-4405
    • Wu L, Adams M, Carter T, Chen R, Muller G, Stirling D, Schafer P, Bartlett JB: Lenalidomide enhances natural killer cells and monocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20+ tumor cells. Clin Cancer Res 14:4650-4657, 2008. doi: 10.1158/1078-0432.CCR-07-4405
    • (2008) Clin Cancer Res , vol.14 , pp. 4650-4657
    • Wu, L.1    Adams, M.2    Carter, T.3    Chen, R.4    Muller, G.5    Stirling, D.6    Schafer, P.7    Bartlett, J.B.8
  • 8
    • 55349093022 scopus 로고    scopus 로고
    • Development and validation of a highly sensitive liquid chromatography/ mass spectrometry method for simultaneous quantification of lenalidomide and flavopiridol in human plasma
    • in press
    • Liu Q, Farley KL, Johnson KA, et al.: Development and validation of a highly sensitive liquid chromatography/mass spectrometry method for simultaneous quantification of lenalidomide and flavopiridol in human plasma. Ther Drug Monit, in press, 2008
    • (2008) Ther Drug Monit
    • Liu, Q.1    Farley, K.L.2    Johnson, K.A.3
  • 9
    • 36148973115 scopus 로고    scopus 로고
    • Pharmacokinetics of lenalidomide in subjects with various degrees of renal impairment and in subjects on hemodialysis
    • doi: 10.1177/0091270007309563
    • Chen N, Lau H, Kong L, Kumar G, Zeldis JB, Knight R, Laskin OL: Pharmacokinetics of lenalidomide in subjects with various degrees of renal impairment and in subjects on hemodialysis. Clin Pharmacol 47:1466-1475, 2007. doi: 10.1177/0091270007309563
    • (2007) Clin Pharmacol , vol.47 , pp. 1466-1475
    • Chen, N.1    Lau, H.2    Kong, L.3    Kumar, G.4    Zeldis, J.B.5    Knight, R.6    Laskin, O.L.7
  • 12
    • 18544390035 scopus 로고    scopus 로고
    • Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing eryhtropoiesis and promoting myelopoiesis
    • doi: 10.1182/blood-2004-03-0828
    • Koh KR, Janz M, Mapara MY, Lemke B, Stirling D, Dörken B, Zenke M, Lentzsch S: Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing eryhtropoiesis and promoting myelopoiesis. Blood 105:3833-3840, 2005. doi: 10.1182/ blood-2004-03-0828
    • (2005) Blood , vol.105 , pp. 3833-3840
    • Koh, K.R.1    Janz, M.2    Mapara, M.Y.3    Lemke, B.4    Stirling, D.5    Dörken, B.6    Zenke, M.7    Lentzsch, S.8
  • 15
    • 38349113462 scopus 로고    scopus 로고
    • The role of lenalidomide in the management of myelodysplasia with del 5q
    • doi: 10.1111/j.1365-2141.2007.06910.x
    • Kelaidi C, Eclache V, Fenaux P: The role of lenalidomide in the management of myelodysplasia with del 5q. Br J Haematol 140:267-278, 2008. doi: 10.1111/j.1365-2141.2007.06910.x
    • (2008) Br J Haematol , vol.140 , pp. 267-278
    • Kelaidi, C.1    Eclache, V.2    Fenaux, P.3
  • 19
    • 33644831033 scopus 로고    scopus 로고
    • Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group
    • doi: 10.1200/JCO.2005.03.0221
    • Rajkumar SV, Blood E, Vesole D, Fonseca R, Greipp PR: Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol 24:431-436, 2006. doi: 10.1200/JCO.2005.03.0221
    • (2006) J Clin Oncol , vol.24 , pp. 431-436
    • Rajkumar, S.V.1    Blood, E.2    Vesole, D.3    Fonseca, R.4    Greipp, P.R.5
  • 20
    • 43749117945 scopus 로고    scopus 로고
    • Multicenter, randomized, double-blind, placebo-controlled study of thalidomide plus dexamethasone compared with dexamethasone as initial therapy for newly diagnosed multiple myeloma
    • doi: 10.1200/JCO.2007.14.1853
    • Rajkumar SV, Rosiñol L, Hussein M, Catalano J, Jedrzejczak W, Lucy L, Olesnyckyj M, Yu Z, Knight R, Zeldis JB, Bladé J: Multicenter, randomized, double-blind, placebo-controlled study of thalidomide plus dexamethasone compared with dexamethasone as initial therapy for newly diagnosed multiple myeloma. J Clin Oncol 26:2171-2177, 2008. doi: 10.1200/JCO.2007.14.1853
    • (2008) J Clin Oncol , vol.26 , pp. 2171-2177
    • Rajkumar, S.V.1    Rosiñol, L.2    Hussein, M.3    Catalano, J.4    Jedrzejczak, W.5    Lucy, L.6    Olesnyckyj, M.7    Yu, Z.8    Knight, R.9    Zeldis, J.B.10    Bladé, J.11
  • 21
    • 51649117633 scopus 로고    scopus 로고
    • A systematic review of phase II trials of thalidomide/dexamethasone combination therapy in patients with relapsed or refractory multiple myeloma
    • Von Lillienfeld-Toal M, Hahn-Ast C, Furkert K, et al.: A systematic review of phase II trials of thalidomide/dexamethasone combination therapy in patients with relapsed or refractory multiple myeloma. Eur J Haematol, 2008, 81:247-252
    • (2008) Eur J Haematol , vol.81 , pp. 247-252
    • Von Lillienfeld-Toal, M.1    Hahn-Ast, C.2    Furkert, K.3
  • 22
    • 54049130077 scopus 로고    scopus 로고
    • Seven year median time to progression with thalidomide for smouldering myeloma: Partial response identifies subset requiring earlier salvage therapy for symptomatic disease
    • Barlogie B, Van Rhee F, Shaughnessy JD Jr, et al.: Seven year median time to progression with thalidomide for smouldering myeloma: Partial response identifies subset requiring earlier salvage therapy for symptomatic disease. Blood, 2008, 112:3122-3125
    • (2008) Blood , vol.112 , pp. 3122-3125
    • Barlogie, B.1    Van Rhee, F.2    Shaughnessy Jr., J.D.3
  • 24
    • 54049135250 scopus 로고    scopus 로고
    • Oral melphalan, prednisone, and thalidomide in elderly patients with multiple myeloma: Updated results of a randomized, controlled trial
    • Palumbo A, Bringhen S, Liberati AM, et al.: Oral melphalan, prednisone, and thalidomide in elderly patients with multiple myeloma: Updated results of a randomized, controlled trial. Blood, 2008, 112:3107-3114
    • (2008) Blood , vol.112 , pp. 3107-3114
    • Palumbo, A.1    Bringhen, S.2    Liberati, A.M.3
  • 26
    • 54049148621 scopus 로고    scopus 로고
    • Thalidomide arm of total therapy 2 improves complete remission duration and survival in myeloma patients with metaphase cytogenetic abnormalities
    • Barlogie B, Pineda-Roman M, van Rhee F, et al.: Thalidomide arm of total therapy 2 improves complete remission duration and survival in myeloma patients with metaphase cytogenetic abnormalities. Blood, 2008, 112:3115-3121
    • (2008) Blood , vol.112 , pp. 3115-3121
    • Barlogie, B.1    Pineda-Roman, M.2    van Rhee, F.3
  • 28
    • 49649096625 scopus 로고    scopus 로고
    • Thalidomide in multiple myeloma-clinical trials and aspects of drug metabolism and toxicity
    • Breitkreutz I, Anderson KC: Thalidomide in multiple myeloma-clinical trials and aspects of drug metabolism and toxicity. Expert Opin Drug Metab Toxicol 4:973-985
    • Expert Opin Drug Metab Toxicol , vol.4 , pp. 973-985
    • Breitkreutz, I.1    Anderson, K.C.2
  • 30
    • 46749133562 scopus 로고    scopus 로고
    • A meta-analysis and systematic review of thalidomide for patients with previously untreated multiple myeloma
    • doi: 10.1016/j.ctrv.2008.02.003
    • Hicks LK, Haynes AE, Reece DE, Walker IR, Herst JA, Meyer RM, Imrie K: A meta-analysis and systematic review of thalidomide for patients with previously untreated multiple myeloma. Cancer Treat Rev 34:442-452, 2008. doi: 10.1016/j.ctrv.2008.02.003
    • (2008) Cancer Treat Rev , vol.34 , pp. 442-452
    • Hicks, L.K.1    Haynes, A.E.2    Reece, D.E.3    Walker, I.R.4    Herst, J.A.5    Meyer, R.M.6    Imrie, K.7
  • 31
    • 44249092118 scopus 로고    scopus 로고
    • The addition of liposomal doxorubicin to bortezomib, thalidomide and dexamethasone significantly improves clinical outcome of advanced multiple myeloma
    • doi: 10.1111/j.1365-2141.2008.07147.x
    • Ciolli S, Leoni F, Casini C, Breschi C, Santini V, Bosi A: The addition of liposomal doxorubicin to bortezomib, thalidomide and dexamethasone significantly improves clinical outcome of advanced multiple myeloma. Br J Haematol 141:814-819, 2008. doi: 10.1111/j.1365-2141.2008.07147.x
    • (2008) Br J Haematol , vol.141 , pp. 814-819
    • Ciolli, S.1    Leoni, F.2    Casini, C.3    Breschi, C.4    Santini, V.5    Bosi, A.6
  • 32
    • 57849161431 scopus 로고    scopus 로고
    • The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesis
    • in press
    • Terpos E, Kastritis E, Roussou M, et al.: The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesis. Leukemia, in press, 2008
    • (2008) Leukemia
    • Terpos, E.1    Kastritis, E.2    Roussou, M.3
  • 33
    • 57649198069 scopus 로고    scopus 로고
    • Thalidomide and rituximab in Waldenstrom's macroglobulinemia
    • in press
    • Treon SP, Soumerai JD, Branagan AR, et al.: Thalidomide and rituximab in Waldenstrom's macroglobulinemia. Blood, in press, 2008
    • (2008) Blood
    • Treon, S.P.1    Soumerai, J.D.2    Branagan, A.R.3
  • 36
    • 40449135275 scopus 로고    scopus 로고
    • Alternate day pomalidomide retains anti-myeloma effect with reduced adverse events and evidence of in vivo immunomodulation
    • doi: 10.1111/j.1365-2141.2008.07013.x
    • Streetly MJ, Gyertson K, Daniel Y, Zeldis JB, Kazmi M, Schey SA: Alternate day pomalidomide retains anti-myeloma effect with reduced adverse events and evidence of in vivo immunomodulation. Br J Haematol 141: 41-51, 2008. doi: 10.1111/j.1365-2141.2008.07013.x
    • (2008) Br J Haematol , vol.141 , pp. 41-51
    • Streetly, M.J.1    Gyertson, K.2    Daniel, Y.3    Zeldis, J.B.4    Kazmi, M.5    Schey, S.A.6
  • 37
    • 4344693453 scopus 로고    scopus 로고
    • Phase I study of an immunomodulatory thalidomide analog, CC-4047, in relapsed or refractory multiple myeloma
    • doi: 10.1200/JCO.2004.10.052
    • Schey SA, Fields P, Bartlett JB, Clarke IA, Aahan G, Knight RD, Streetly M, Dalgleish AG: Phase I study of an immunomodulatory thalidomide analog, CC-4047, in relapsed or refractory multiple myeloma. J Clin Oncol 22:3269-3276, 2004. doi: 10.1200/JCO.2004.10.052
    • (2004) J Clin Oncol , vol.22 , pp. 3269-3276
    • Schey, S.A.1    Fields, P.2    Bartlett, J.B.3    Clarke, I.A.4    Aahan, G.5    Knight, R.D.6    Streetly, M.7    Dalgleish, A.G.8
  • 38
    • 54049156803 scopus 로고    scopus 로고
    • Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma
    • Breitkreutz I, Raab MS, Vallet S, et al.: Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma. Leukemia, 2008, 22:1925-1932
    • (2008) Leukemia , vol.22 , pp. 1925-1932
    • Breitkreutz, I.1    Raab, M.S.2    Vallet, S.3
  • 41
    • 58149384555 scopus 로고    scopus 로고
    • Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposure
    • in press
    • Wang M, Dimopoulos MA, Chen C, et al.: Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposure. Blood, in press, 2008
    • (2008) Blood
    • Wang, M.1    Dimopoulos, M.A.2    Chen, C.3
  • 45
    • 14944374754 scopus 로고    scopus 로고
    • Antibiotics directly induce apoptosis in B cell lymphoma cells derived from BALB/c mice
    • Ohara T, Monishita T, SuzukiH, Massaoka T, Ishi H, Hibi T: Antibiotics directly induce apoptosis in B cell lymphoma cells derived from BALB/c mice. Anticancer Res 24:3723-3730, 2004.
    • (2004) Anticancer Res , vol.24 , pp. 3723-3730
    • Ohara, T.1    Monishita, T.2    Suzuki, H.3    Massaoka, T.4    Ishi, H.5    Hibi, T.6
  • 46
    • 44649143334 scopus 로고    scopus 로고
    • Compromised stem cell mobilization following induction therapy with lenalidomide in myeloma
    • doi: 10.1038/sj.leu.2405100
    • Paripati H, Stewart AK, Cabou S, et al.: Compromised stem cell mobilization following induction therapy with lenalidomide in myeloma. Leukemia 2008, 22:1282-1284. doi: 10.1038/sj.leu.2405100
    • (2008) Leukemia , vol.22 , pp. 1282-1284
    • Paripati, H.1    Stewart, A.K.2    Cabou, S.3
  • 47
    • 45149129384 scopus 로고    scopus 로고
    • Effect of lenalidomide therapy on mobilization of peripheral blood stem cells in previously untreated myeloma patients
    • doi: 10.1038/sj.leu.2405035
    • Mazumder A, Kaufman J, Niesvizky R, Lonial S, Vesole D, Jagannath S: Effect of lenalidomide therapy on mobilization of peripheral blood stem cells in previously untreated myeloma patients. Leukemia 22:1280-1281, 2008. doi: 10.1038/sj.leu.2405035
    • (2008) Leukemia , vol.22 , pp. 1280-1281
    • Mazumder, A.1    Kaufman, J.2    Niesvizky, R.3    Lonial, S.4    Vesole, D.5    Jagannath, S.6
  • 50
    • 43049086661 scopus 로고    scopus 로고
    • Lenalidomide in the treatment of multiple myeloma: A review
    • doi: 10.1111/j.1365-2710.2008.00920.x
    • Armoiry X, Aulagner G, Facon T: Lenalidomide in the treatment of multiple myeloma: A review. J Clin Pharm Ther 33:219-226, 2008. doi: 10.1111/j.1365-2710.2008.00920.x
    • (2008) J Clin Pharm Ther , vol.33 , pp. 219-226
    • Armoiry, X.1    Aulagner, G.2    Facon, T.3
  • 51
    • 47649104483 scopus 로고    scopus 로고
    • Treatment of plasma cell dyscrasias with lenalidomide
    • doi: 10.1038/leu.2008.123
    • Dimopoulos MA, Kastritis E, Rajkumar SV: Treatment of plasma cell dyscrasias with lenalidomide. Leukemia 22:1343-1353, 2008. doi: 10.1038/ leu.2008.123
    • (2008) Leukemia , vol.22 , pp. 1343-1353
    • Dimopoulos, M.A.1    Kastritis, E.2    Rajkumar, S.V.3
  • 52
    • 41549123588 scopus 로고    scopus 로고
    • A review of lenalidomide in combination with dexamethasone for the treatment of multiple myeloma
    • Hideshima T, Raje N, Richardson PG, Anderson KC: A review of lenalidomide in combination with dexamethasone for the treatment of multiple myeloma. Ther Clin Risk Manag 4:129-136, 2008.
    • (2008) Ther Clin Risk Manag , vol.4 , pp. 129-136
    • Hideshima, T.1    Raje, N.2    Richardson, P.G.3    Anderson, K.C.4
  • 53
    • 54249169669 scopus 로고    scopus 로고
    • Multiple myeloma, an update on diagnosis and treatment
    • Caers J, Vande Broek I, De Raeve H, et al.: Multiple myeloma, an update on diagnosis and treatment. Eur J Haematol, 2008, 81:329-343
    • (2008) Eur J Haematol , vol.81 , pp. 329-343
    • Caers, J.1    Vande Broek, I.2    De Raeve, H.3
  • 54
    • 42049084260 scopus 로고    scopus 로고
    • Novel anti-myeloma agents and angiogenesis
    • doi: 10.1080/10428190701861686
    • Anargyrou K, Dimopoulos MA, Sezer O, Terpos E: Novel anti-myeloma agents and angiogenesis. Leuk Lymphoma 49:677-689, 2008. doi: 10.1080/ 10428190701861686
    • (2008) Leuk Lymphoma , vol.49 , pp. 677-689
    • Anargyrou, K.1    Dimopoulos, M.A.2    Sezer, O.3    Terpos, E.4
  • 55
    • 54049131660 scopus 로고    scopus 로고
    • Frontline treatment of multiple myeloma in elderly patients
    • Moreau P, Hulin C, Facon T: Frontline treatment of multiple myeloma in elderly patients. Blood Rev, 2008, 22:303-309
    • (2008) Blood Rev , vol.22 , pp. 303-309
    • Moreau, P.1    Hulin, C.2    Facon, T.3
  • 57
    • 58149241976 scopus 로고    scopus 로고
    • Lenalidomide in combination with dexamethasone for the treatment of relapsed or refractory multiple myeloma
    • in press
    • Palumbo A, Dimopoulos M, Miguel JS, et al.: Lenalidomide in combination with dexamethasone for the treatment of relapsed or refractory multiple myeloma. Blood Rev, in press, 2008
    • (2008) Blood Rev
    • Palumbo, A.1    Dimopoulos, M.2    Miguel, J.S.3
  • 58
    • 38349124445 scopus 로고    scopus 로고
    • Should prophylactic granulocyte-colony stimulating factor be used in multiple myeloma patients developing neutropenia under lenalidomide-based therapy?
    • doi: 10.1111/j.1365-2141.2007.06946.x
    • Mateos MV, Garcia-Sanz R, Colado E, Olazbal J, San-Miguel J: Should prophylactic granulocyte-colony stimulating factor be used in multiple myeloma patients developing neutropenia under lenalidomide-based therapy? Br J Haematol 140:324-326, 2008. doi: 10.1111/ j.1365-2141.2007.06946.x
    • (2008) Br J Haematol , vol.140 , pp. 324-326
    • Mateos, M.V.1    Garcia-Sanz, R.2    Colado, E.3    Olazbal, J.4    San-Miguel, J.5
  • 61
    • 33744482623 scopus 로고    scopus 로고
    • Immunomodulating drugs for chronic lymphocytic leukemia
    • doi: 10.1016/S1470-2045(06)70723-9
    • Chanan-Khan A, Porter CW, Immunomodulating drugs for chronic lymphocytic leukemia. Lancet Oncol 7:480-488, 2006. doi: 10.1016/ S1470-2045(06)70723-9
    • (2006) Lancet Oncol , vol.7 , pp. 480-488
    • Chanan-Khan, A.1    Porter, C.W.2
  • 62
    • 27744597929 scopus 로고    scopus 로고
    • Results of a phase 1 clinical trial of thalidomide in combination with fludarabine as initial therapy for patients with treatment-requiring chronic lymphocytic leukemia (CLL)
    • doi: 10.1182/blood-2005-02-0669
    • Chanan-Khan A, Miller KC, Takeshita K, Koryzna A, Donohue K, Bernstein ZP, Mohr A, Klippenstein D, Wallace P, Zeldis JB, Berger C, Czuczmzn MS: Results of a phase 1 clinical trial of thalidomide in combination with fludarabine as initial therapy for patients with treatment-requiring chronic lymphocytic leukemia (CLL). Blood 106:3348-3352, 2005. doi: 10.1182/blood-2005-02-0669
    • (2005) Blood , vol.106 , pp. 3348-3352
    • Chanan-Khan, A.1    Miller, K.C.2    Takeshita, K.3    Koryzna, A.4    Donohue, K.5    Bernstein, Z.P.6    Mohr, A.7    Klippenstein, D.8    Wallace, P.9    Zeldis, J.B.10    Berger, C.11    Czuczmzn, M.S.12
  • 66
    • 36849068944 scopus 로고    scopus 로고
    • Tumor lysis syndrome/tumor flare reaction in lenalidomide-treated chronic lymphocytic leukemia
    • doi: 10.1200/JCO.2007.14.2141
    • Moutouh-de-Parseval LA, Weiss L, DeLAp RJ, Knight RD, Zeldis JB: Tumor lysis syndrome/tumor flare reaction in lenalidomide-treated chronic lymphocytic leukemia. J Clin Oncol 25:5047, 2007. doi: 10.1200/ JCO.2007.14.2141
    • (2007) J Clin Oncol , vol.25 , pp. 5047
    • Moutouh-de-Parseval, L.A.1    Weiss, L.2    DeLAp, R.J.3    Knight, R.D.4    Zeldis, J.B.5
  • 67
    • 54249086272 scopus 로고    scopus 로고
    • Lenalidomide-associated tumor flare reaction is manageable in patients with chronic lymphocytic leukemia
    • Chanan-Khan AA, Whitworth A, Bangia N, et al.: Lenalidomide-associated tumor flare reaction is manageable in patients with chronic lymphocytic leukemia. J Clin Oncol, 2008, 26:4851-4852
    • (2008) J Clin Oncol , vol.26 , pp. 4851-4852
    • Chanan-Khan, A.A.1    Whitworth, A.2    Bangia, N.3
  • 68
    • 58149399362 scopus 로고    scopus 로고
    • Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells
    • in press
    • Lapalombella R, Yu B, Triantafillou G, et al.: Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells. Blood, in press, 2008
    • (2008) Blood
    • Lapalombella, R.1    Yu, B.2    Triantafillou, G.3
  • 69
    • 70149098261 scopus 로고    scopus 로고
    • Concurrent B-cell chronic lymphocytic leukemia and multiple myeloma treated successfully with lenalidomide
    • in press
    • Srinivasan S, Schiffer CA: Concurrent B-cell chronic lymphocytic leukemia and multiple myeloma treated successfully with lenalidomide. Leuk Res, in press, 2008
    • (2008) Leuk Res
    • Srinivasan, S.1    Schiffer, C.A.2
  • 70
    • 0030463429 scopus 로고    scopus 로고
    • Occurrence of myeloma in a chronic lymphocytic leukemia patient after response to differentiation therapy with interleukin-4
    • doi: 10.3109/10428199609054873
    • Makower D, Venkatraj U, Dutcher JP, Wiernik PH: Occurrence of myeloma in a chronic lymphocytic leukemia patient after response to differentiation therapy with interleukin-4. Leuk Lymphoma 23:617-619, 1996. doi: 10.3109/ 10428199609054873
    • (1996) Leuk Lymphoma , vol.23 , pp. 617-619
    • Makower, D.1    Venkatraj, U.2    Dutcher, J.P.3    Wiernik, P.H.4
  • 71
    • 38949106198 scopus 로고    scopus 로고
    • Thalidomide has limited single-agent activity in relapsed or refractory indolent non-Hodgkin lymphomas: A phase II trial of the Cancer and Leukemia Group B
    • doi: 10.1111/j.1365-2141.2007.06937.x
    • Smith SM, Grinblatt D, Johnson JL, Niedzwiecki D, Rizzieri D, Bartlett NL, Cheson BD: Thalidomide has limited single-agent activity in relapsed or refractory indolent non-Hodgkin lymphomas: A phase II trial of the Cancer and Leukemia Group B. Br J Haematol 140:313-319, 2008. doi: 10.1111/j.1365-2141.2007.06937.x
    • (2008) Br J Haematol , vol.140 , pp. 313-319
    • Smith, S.M.1    Grinblatt, D.2    Johnson, J.L.3    Niedzwiecki, D.4    Rizzieri, D.5    Bartlett, N.L.6    Cheson, B.D.7
  • 73
    • 49249117801 scopus 로고    scopus 로고
    • CC-4047 promotes Th1 cell differentiation and reprograms polarized human Th2 cells by enhancing transcription factor T-bet
    • doi: 10.1016/j.clim.2008.04.009
    • Xu W, Celeridad M, Sankar S, Webb DR, Bennett BL: CC-4047 promotes Th1 cell differentiation and reprograms polarized human Th2 cells by enhancing transcription factor T-bet. Clin Immunol 128:392-399, 2008. doi: 10.1016/j.clim.2008.04.009
    • (2008) Clin Immunol , vol.128 , pp. 392-399
    • Xu, W.1    Celeridad, M.2    Sankar, S.3    Webb, D.R.4    Bennett, B.L.5
  • 74
    • 54449095901 scopus 로고    scopus 로고
    • Lenalidomide monotherapy in relapsed or refractory aggressive non-Hodgkin's lymphoma
    • Wiernik PH, Lossos IS, Tuscano JM, et al.: Lenalidomide monotherapy in relapsed or refractory aggressive non-Hodgkin's lymphoma. J Clin Oncol, 2008, 26:4952-4957
    • (2008) J Clin Oncol , vol.26 , pp. 4952-4957
    • Wiernik, P.H.1    Lossos, I.S.2    Tuscano, J.M.3
  • 76
    • 70149115300 scopus 로고    scopus 로고
    • Results from a phase II study investigating the efficacy and safety of linalidomide oral monotherapy in relapsed or refractory indolent non-Hodgkin's lymphoma
    • Wiernik PH, Vose JM, Moore TD, et al.: Results from a phase II study investigating the efficacy and safety of linalidomide oral monotherapy in relapsed or refractory indolent non-Hodgkin's lymphoma. Proc Eur Hematol Assn, 2008
    • (2008) Proc Eur Hematol Assn
    • Wiernik, P.H.1    Vose, J.M.2    Moore, T.D.3
  • 77
    • 70149102959 scopus 로고    scopus 로고
    • Phase II multi-center study of lenalidomide oral monotherapy in relapsed or refractory indolent non-Hodgkin's lymphoma
    • submitted
    • Witzig TE, Wiernik PH, Moore T, et al.: Phase II multi-center study of lenalidomide oral monotherapy in relapsed or refractory indolent non-Hodgkin's lymphoma. J Clin Oncol, submitted, 2008
    • (2008) J Clin Oncol
    • Witzig, T.E.1    Wiernik, P.H.2    Moore, T.3
  • 78
    • 36849024949 scopus 로고    scopus 로고
    • Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo
    • Reddy N, Hernandez-Ilizaliturri FJ, Deeb G, Roth M, Vaughn M, Knight J, Wallace P, Czuczman MS: Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo. Br J Haematol 140:36-45, 2008.
    • (2008) Br J Haematol , vol.140 , pp. 36-45
    • Reddy, N.1    Hernandez-Ilizaliturri, F.J.2    Deeb, G.3    Roth, M.4    Vaughn, M.5    Knight, J.6    Wallace, P.7    Czuczman, M.S.8
  • 79
    • 23844435619 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model
    • doi: 10.1158/1078-0432.CCR-05-0577
    • Hernandez-Ilizaliturri FJ, Reddy N, Holkova B, Ottman E, Czuczman MS: Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model. Clin Cancer Res 11:5984-5992, 2005. doi: 10.1158/1078-0432.CCR-05-0577
    • (2005) Clin Cancer Res , vol.11 , pp. 5984-5992
    • Hernandez-Ilizaliturri, F.J.1    Reddy, N.2    Holkova, B.3    Ottman, E.4    Czuczman, M.S.5
  • 80
    • 41149168649 scopus 로고    scopus 로고
    • Lenalidomide for the treatment of B-cell malignancies
    • doi: 10.1200/JCO.2007.14.5367
    • Chanan-Khan AA, Cheson BD: Lenalidomide for the treatment of B-cell malignancies. J Clin Oncol 26:1544-1552, 2008. doi: 10.1200/ JCO.2007.14.5367
    • (2008) J Clin Oncol , vol.26 , pp. 1544-1552
    • Chanan-Khan, A.A.1    Cheson, B.D.2
  • 81
    • 50049092599 scopus 로고    scopus 로고
    • Treatment of follicular non-Hodgkin's lymphoma: The old and the new
    • Friedberg JW: Treatment of follicular non-Todgkin's lymphoma: the old and the new. Semin Hematol 45S2:S2-S6, 2008.
    • (2008) Semin Hematol , vol.45 S2
    • Friedberg, J.W.1
  • 82
    • 50049100613 scopus 로고    scopus 로고
    • Targeted treatment and new agents in diffuse large B-cell lymphoma
    • Leonard JP, Martin P, Barrientos J, Elstrom: Targeted treatment and new agents in diffuse large B-cell lymphoma. Semin Hematol 45S2:S11-S16, 2008.
    • (2008) Semin Hematol , vol.45 S2
    • Leonard, J.P.1    Martin, P.2    Barrientos, J.3    Elstrom4
  • 84
    • 60749095642 scopus 로고    scopus 로고
    • Treatment of patients with advanced cardiac AL amyloidosis with oral melphalan, dexamethasone, and thalidomide
    • in press
    • Palladini G, Russo P, Lavatelli F, et al.: Treatment of patients with advanced cardiac AL amyloidosis with oral melphalan, dexamethasone, and thalidomide. Ann Hematol, in press, 2008
    • (2008) Ann Hematol
    • Palladini, G.1    Russo, P.2    Lavatelli, F.3
  • 86
    • 33745291997 scopus 로고    scopus 로고
    • Thromboembolism risk reduction in multiple myeloma patients treated with immunomodulatory drug combinations
    • Hussein MA: Thromboembolism risk reduction in multiple myeloma patients treated with immunomodulatory drug combinations. Thromb Haemost 95:924-930, 2006.
    • (2006) Thromb Haemost , vol.95 , pp. 924-930
    • Hussein, M.A.1
  • 87
    • 33646494190 scopus 로고    scopus 로고
    • Lenalidomide and venous thrombosis in multiple myeloma
    • doi: 10.1056/NEJMc053530
    • Knight R, DeLap RJ, Zeldis JB: Lenalidomide and venous thrombosis in multiple myeloma. N Engl J Med 354:2079-2080, 2006 doi: 10.1056/ NEJMc053530
    • (2006) N Engl J Med , vol.354 , pp. 2079-2080
    • Knight, R.1    DeLap, R.J.2    Zeldis, J.B.3
  • 89
    • 44949239424 scopus 로고    scopus 로고
    • Pathphysiological considerations in thrombophilia in the treatment of multiple myeloma with thalidomide and derivates
    • Gieseler F: Pathphysiological considerations in thrombophilia in the treatment of multiple myeloma with thalidomide and derivates. Thromb Haemost 99:1001-1007, 2008.
    • (2008) Thromb Haemost , vol.99 , pp. 1001-1007
    • Gieseler, F.1
  • 90
    • 41149161749 scopus 로고    scopus 로고
    • Thromboembolic events with lenalidomide-base therapy for multiple myeloma
    • doi: 10.1002/cncr.23336
    • Menon SP, Rajkumar SV, Lacy M, Falco P, Palumbo A: Thromboembolic events with lenalidomide-base therapy for multiple myeloma. Cancer 112:1522-1528, 2008. doi: 10.1002/cncr.23336
    • (2008) Cancer , vol.112 , pp. 1522-1528
    • Menon, S.P.1    Rajkumar, S.V.2    Lacy, M.3    Falco, P.4    Palumbo, A.5
  • 92
    • 58149380751 scopus 로고    scopus 로고
    • Genetic associations with thalidomide mediated venous thrombotic events in myeloma identified using targeted genotyping
    • in press
    • Johnson DC, Corthais S, Ramos C, et al.: Genetic associations with thalidomide mediated venous thrombotic events in myeloma identified using targeted genotyping. Blood, in press, 2008
    • (2008) Blood
    • Johnson, D.C.1    Corthais, S.2    Ramos, C.3
  • 93
    • 33745590139 scopus 로고    scopus 로고
    • Thrombotic complications in patients with newly diagnosed multiple myeloma treated with lenalidomide and dexamethasone: Benefit of aspirin prophylaxis
    • doi: 10.1182/blood-2006-01-0154
    • Zonder JA, Barlogie B, Durie BGM, et al.: Thrombotic complications in patients with newly diagnosed multiple myeloma treated with lenalidomide and dexamethasone: Benefit of aspirin prophylaxis. Blood 2006, 108:403. doi: 10.1182/blood-2006-01-0154
    • (2006) Blood , vol.108 , pp. 403
    • Zonder, J.A.1    Barlogie, B.2    Durie, B.G.M.3
  • 95
    • 44449135859 scopus 로고    scopus 로고
    • Thromboembolic risk associated with use of angiogenesis inhibitors used for the treatment of cancers
    • doi: 10.1016/j.patbio.2008.02.013
    • Drouet L: Thromboembolic risk associated with use of angiogenesis inhibitors used for the treatment of cancers. Pathol Biol (Paris) 56:195-204, 2008. doi: 10.1016/j.patbio.2008.02.013
    • (2008) Pathol Biol (Paris) , vol.56 , pp. 195-204
    • Drouet, L.1
  • 96
    • 70149110476 scopus 로고    scopus 로고
    • Effective prophylaxis of thromboembolic complications with low molecular weight heparin in relapsed multiple myeloma patients treated with lenalidomide and dexamethasone
    • in press
    • Klein U, Kosely F, Hillenga J, et al.: Effective prophylaxis of thromboembolic complications with low molecular weight heparin in relapsed multiple myeloma patients treated with lenalidomide and dexamethasone. Ann Hematol, in press, 2008
    • (2008) Ann Hematol
    • Klein, U.1    Kosely, F.2    Hillenga, J.3
  • 97
    • 33845442041 scopus 로고    scopus 로고
    • Thalidomide- and lenalidomide-associated thromboembolism among patients with cancer
    • doi: 10.1001/jama.296.21.2558-c
    • Bennett CL, Angelotta C, Yarnold PR, Evens AM, Zonder JA, Raisch DW, Richardson P: Thalidomide- and lenalidomide-associated thromboembolism among patients with cancer. JAMA 296:2558-2560, 2006. doi: 10.1001/ jama.296.21.2558-c
    • (2006) JAMA , vol.296 , pp. 2558-2560
    • Bennett, C.L.1    Angelotta, C.2    Yarnold, P.R.3    Evens, A.M.4    Zonder, J.A.5    Raisch, D.W.6    Richardson, P.7
  • 99
    • 33846318493 scopus 로고    scopus 로고
    • Riskof thrombosis with lenalidomide and its prevention with aspirin
    • doi: 10.1378/chest.06-2360
    • Hirsh J: Riskof thrombosis with lenalidomide and its prevention with aspirin. Chest 131:275-277, 2007. doi: 10.1378/chest.06-2360
    • (2007) Chest , vol.131 , pp. 275-277
    • Hirsh, J.1
  • 100
    • 37149032140 scopus 로고    scopus 로고
    • Lenalidomide-associated hypothyroidism
    • doi: 10.1080/10428190701704613
    • Menon S, Habermann T, Witzig T: Lenalidomide-associated hypothyroidism. Leuk Lymphoma 48:2465-2467, 2007. doi: 10.1080/10428190701704613
    • (2007) Leuk Lymphoma , vol.48 , pp. 2465-2467
    • Menon, S.1    Habermann, T.2    Witzig, T.3
  • 101
    • 36749030072 scopus 로고    scopus 로고
    • Lenalidomide-induced warm autoimmune hemolytic anemia
    • doi: 10.1200/JCO.2006.08.4053
    • Darabi K, Kantammei S, Wiernik PH: Lenalidomide-induced warm autoimmune hemolytic anemia. J Clin Oncol 24:e59, 2006. doi: 10.1200/ JCO.2006.08.4053
    • (2006) J Clin Oncol , vol.24
    • Darabi, K.1    Kantammei, S.2    Wiernik, P.H.3
  • 102
    • 33646736537 scopus 로고    scopus 로고
    • The neutropenia induced by the thalidomide analogue CC-4047 in patients with multiple myeloma is associated with an increased percentage of neutrophils bearing CD64
    • doi: 10.1016/j.intimp.2006.03.001
    • McCarthy DA, Macey MG, Streetly M, Schey SA, Brown KA: The neutropenia induced by the thalidomide analogue CC-4047 in patients with multiple myeloma is associated with an increased percentage of neutrophils bearing CD64. Int Immunopharmacol 6:1194-1203, 2006. doi: 10.1016/ j.intimp.2006.03.001
    • (2006) Int Immunopharmacol , vol.6 , pp. 1194-1203
    • McCarthy, D.A.1    Macey, M.G.2    Streetly, M.3    Schey, S.A.4    Brown, K.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.