메뉴 건너뛰기




Volumn 2, Issue 2, 2010, Pages 970-988

VEGF and pleiotrophin modulate the immune profile of breast cancer

Author keywords

Angiogenesis; Anti VEGF; Macrophage; Pleiotrophin; VEGF

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; CAPECITABINE; GU 81; PACLITAXEL; PLEIOTROPHIN; SORAFENIB; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN ANTIBODY; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 1 ANTIBODY; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 2 ANTIBODY;

EID: 79952267749     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers2020970     Document Type: Review
Times cited : (21)

References (104)
  • 1
    • 67650385302 scopus 로고    scopus 로고
    • American Cancer Society, American Cancer Society: Atlanta, GA, USA, 2009
    • American Cancer Society. Cancer Facts and Figures 2009; American Cancer Society: Atlanta, GA, USA, 2009.
    • (2009) Cancer Facts and Figures
  • 2
    • 34250190230 scopus 로고    scopus 로고
    • Cancer initiation and progression: Involvement of stem cells and the microenvironment
    • Tysnes, B.B.; Bjerkvig, R. Cancer initiation and progression: involvement of stem cells and the microenvironment. Biochim. Biophys. Acta 2007, 1775, 283-297.
    • (2007) Biochim. Biophys. Acta. , vol.1775 , pp. 283-297
    • Tysnes, B.B.1    Bjerkvig, R.2
  • 3
    • 40349094954 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Balancing immune response: Crosstalk between adaptive and innate immune cells during breast cancer progression
    • DeNardo, D.G.; Coussens, L.M. Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Res. 2007, 9, 212.
    • (2007) Breast Cancer Res , vol.9 , pp. 212
    • Denardo, D.G.1    Coussens, L.M.2
  • 4
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman, J. Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 1971, 285, 1182-1186.
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 5
    • 0036842215 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
    • Dvorak, H.F. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J. Clin. Oncol. 2002, 20, 4368-4380.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 4368-4380
    • Dvorak, H.F.1
  • 6
    • 28144462911 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in tumor angiogenesis and malignancies
    • Pradeep, C.R.; Sunila, E.S.; Kuttan, G. Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in tumor angiogenesis and malignancies. Integr. Cancer Ther. 2005, 4, 315-321.
    • (2005) Integr. Cancer Ther. , vol.4 , pp. 315-321
    • Pradeep, C.R.1    Sunila, E.S.2    Kuttan, G.3
  • 7
    • 0035254646 scopus 로고    scopus 로고
    • Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans
    • Sawano, A.; Iwai, S.; Sakurai, Y.; Ito, M.; Shitara, K.; Nakahata, T.; Shibuya, M. Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans. Blood 2001, 97, 785-791.
    • (2001) Blood , vol.97 , pp. 785-791
    • Sawano, A.1    Iwai, S.2    Sakurai, Y.3    Ito, M.4    Shitara, K.5    Nakahata, T.6    Shibuya, M.7
  • 8
    • 34347205690 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1
    • Lee, T.H.; Seng, S.; Sekine, M.; Hinton, C.; Fu, Y.; Avraham, H.K.; Avraham, S. Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med. 2007, 4, e186.
    • (2007) PLoS Med , vol.4
    • Lee, T.H.1    Seng, S.2    Sekine, M.3    Hinton, C.4    Fu, Y.5    Avraham, H.K.6    Avraham, S.7
  • 9
    • 31544463515 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells
    • Yang, A.D.; Camp, E.R.; Fan, F.; Shen, L.; Gray, M.J.; Liu, W.; Somcio, R.; Bauer, T.W.; Wu, Y.; Hicklin, D.J.; Ellis, L.M. Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells. Cancer Res. 2006, 66, 46-51.
    • (2006) Cancer Res , vol.66 , pp. 46-51
    • Yang, A.D.1    Camp, E.R.2    Fan, F.3    Shen, L.4    Gray, M.J.5    Liu, W.6    Somcio, R.7    Bauer, T.W.8    Wu, Y.9    Hicklin, D.J.10    Ellis, L.M.11
  • 10
    • 58149190795 scopus 로고    scopus 로고
    • Pathways mediating resistance to vascular endothelial growth factor-targeted therapy
    • Ellis, L.M.; Hicklin, D.J. Pathways mediating resistance to vascular endothelial growth factor-targeted therapy. Clin. Cancer Res. 2008, 14, 6371-6375.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 6371-6375
    • Ellis, L.M.1    Hicklin, D.J.2
  • 11
    • 77951692165 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance to tumour anti-angiogenic strategies
    • Grepin, R.; Pages, G. Molecular mechanisms of resistance to tumour anti-angiogenic strategies. J. Oncol. 2010, 2010, 835680.
    • (2010) J. Oncol. , vol.2010 , pp. 835680
    • Grepin, R.1    Pages, G.2
  • 12
    • 0029134066 scopus 로고
    • Basic fibroblast growth factor mediates its effects on committed myeloid progenitors by direct action and has no effect on hematopoietic stem cells
    • Berardi, A.C.; Wang, A.; Abraham, J.; Scadden, D. T. Basic fibroblast growth factor mediates its effects on committed myeloid progenitors by direct action and has no effect on hematopoietic stem cells. Blood 1995, 86, 2123-2129.
    • (1995) Blood , vol.86 , pp. 2123-2129
    • Berardi, A.C.1    Wang, A.2    Abraham, J.3    Scadden, D.T.4
  • 13
    • 0033563162 scopus 로고    scopus 로고
    • Fibroblast growth factor-1 (FGF-1) enhances IL-2 production and nuclear translocation of NF-kappaB in FGF receptor-bearing Jurkat T cells
    • Byrd, V.M.; Ballard, D.W.; Miller, G.G.; Thomas, J.W. Fibroblast growth factor-1 (FGF-1) enhances IL-2 production and nuclear translocation of NF-kappaB in FGF receptor-bearing Jurkat T cells. J. Immunol. 1999, 162, 5853-5859.
    • (1999) J. Immunol. , vol.162 , pp. 5853-5859
    • Byrd, V.M.1    Ballard, D.W.2    Miller, G.G.3    Thomas, J.W.4
  • 14
    • 0028123013 scopus 로고
    • Suppressive effect of basic fibroblast growth factor on transendothelial emigration of CD4(+) T-lymphocyte
    • Kitayama, J.; Nagawa, H.; Yasuhara, H.; Tsuno, N.; Kimura, W.; Shibata, Y.; Muto, T. Suppressive effect of basic fibroblast growth factor on transendothelial emigration of CD4(+) T-lymphocyte. Cancer Res. 1994, 54, 4729-4733.
    • (1994) Cancer Res , vol.54 , pp. 4729-4733
    • Kitayama, J.1    Nagawa, H.2    Yasuhara, H.3    Tsuno, N.4    Kimura, W.5    Shibata, Y.6    Muto, T.7
  • 15
    • 33847749471 scopus 로고    scopus 로고
    • Effect of fibroblast growth factor 2 on stromal cell-derived factor 1 production by bone marrow stromal cells and hematopoiesis
    • Nakayama, T.; Mutsuga, N.; Tosato, G. Effect of fibroblast growth factor 2 on stromal cell-derived factor 1 production by bone marrow stromal cells and hematopoiesis. J. Natl. Cancer Inst. 2007, 99, 223-235.
    • (2007) J. Natl. Cancer Inst. , vol.99 , pp. 223-235
    • Nakayama, T.1    Mutsuga, N.2    Tosato, G.3
  • 16
    • 2342638451 scopus 로고    scopus 로고
    • Endogenous and exogenous fibroblast growth factor-2 modulate wound healing in the chick embryo chorioallantoic membrane
    • Ribatti, D.; Nico, B.; Vacca, A.; Roncali, L.; Presta, M. Endogenous and exogenous fibroblast growth factor-2 modulate wound healing in the chick embryo chorioallantoic membrane. Angiogenesis 1999, 3, 89-95.
    • (1999) Angiogenesis , vol.3 , pp. 89-95
    • Ribatti, D.1    Nico, B.2    Vacca, A.3    Roncali, L.4    Presta, M.5
  • 17
    • 0033848633 scopus 로고    scopus 로고
    • Basic fibroblast growth factor modulates the surface expression of effector cell molecules and primes respiratory burst activity in human neutrophils
    • Takagi, S.; Takahashi, K.; Katsura, Y.; Matsuoka, T.; Ohsaka, A. Basic fibroblast growth factor modulates the surface expression of effector cell molecules and primes respiratory burst activity in human neutrophils. Acta Haematol. 2000, 103, 78-83.
    • (2000) Acta Haematol , vol.103 , pp. 78-83
    • Takagi, S.1    Takahashi, K.2    Katsura, Y.3    Matsuoka, T.4    Ohsaka, A.5
  • 19
    • 34548798765 scopus 로고    scopus 로고
    • Tie2-expressing monocytes and tumor angiogenesis: Regulation by hypoxia and angiopoietin-2
    • Lewis, C.E.; De Palma, M.; Naldini, L. Tie2-expressing monocytes and tumor angiogenesis: regulation by hypoxia and angiopoietin-2. Cancer Res. 2007, 67, 8429-8432.
    • (2007) Cancer Res , vol.67 , pp. 8429-8432
    • Lewis, C.E.1    de Palma, M.2    Naldini, L.3
  • 20
    • 34548545297 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Microenvironmental factors regulating macrophage function in breast tumours: Hypoxia and angiopoietin-2
    • Lewis, C.E.; Hughes, R. Inflammation and breast cancer. Microenvironmental factors regulating macrophage function in breast tumours: hypoxia and angiopoietin-2. Breast Cancer Res. 2007, 9, 209.
    • (2007) Breast Cancer Res , vol.9 , pp. 209
    • Lewis, C.E.1    Hughes, R.2
  • 21
    • 37249055916 scopus 로고    scopus 로고
    • Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells
    • Lin, Y.L.; Liang, Y.C.; Chiang, B.L. Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells. J. Leukoc. Biol. 2007, 82, 1473-1480.
    • (2007) J. Leukoc. Biol. , vol.82 , pp. 1473-1480
    • Lin, Y.L.1    Liang, Y.C.2    Chiang, B.L.3
  • 22
    • 0043156081 scopus 로고    scopus 로고
    • Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor
    • Selvaraj, S.K.; Giri, R.K.; Perelman, N.; Johnson, C.; Malik, P.; Kalra, V.K. Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor. Blood 2003, 102, 1515-1524.
    • (2003) Blood , vol.102 , pp. 1515-1524
    • Selvaraj, S.K.1    Giri, R.K.2    Perelman, N.3    Johnson, C.4    Malik, P.5    Kalra, V.K.6
  • 23
    • 33344464945 scopus 로고    scopus 로고
    • CXCR4: A key receptor in the crosstalk between tumor cells and their microenvironment
    • Burger, J.A.; Kipps, T.J. CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 2006, 107, 1761-1767.
    • (2006) Blood , vol.107 , pp. 1761-1767
    • Burger, J.A.1    Kipps, T.J.2
  • 24
    • 69849088026 scopus 로고    scopus 로고
    • Hematopoietic stem and progenitor cells: Their mobilization and homing to bone marrow and peripheral tissue
    • Schulz, C.; von Andrian, U.H.; Massberg, S. Hematopoietic stem and progenitor cells: their mobilization and homing to bone marrow and peripheral tissue. Immunol. Res. 2009, 44, 160-168.
    • (2009) Immunol. Res. , vol.44 , pp. 160-168
    • Schulz, C.1    von Andrian, U.H.2    Massberg, S.3
  • 25
    • 37549023012 scopus 로고    scopus 로고
    • Pleiotrophin, a multifunctional tumor promoter through induction of tumor angiogenesis, remodeling of the tumor microenvironment, and activation of stromal fibroblasts
    • Perez-Pinera, P.; Chang, Y.; Deuel, T.F. Pleiotrophin, a multifunctional tumor promoter through induction of tumor angiogenesis, remodeling of the tumor microenvironment, and activation of stromal fibroblasts. Cell Cycle 2007, 6, 2877-2883.
    • (2007) Cell Cycle , vol.6 , pp. 2877-2883
    • Perez-Pinera, P.1    Chang, Y.2    Deuel, T.F.3
  • 27
    • 0024317792 scopus 로고
    • An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors
    • Rauvala, H. An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors. EMBO J. 1989, 8, 2933-2941.
    • (1989) EMBO J , vol.8 , pp. 2933-2941
    • Rauvala, H.1
  • 28
    • 0029805056 scopus 로고    scopus 로고
    • Localization of pleiotrophin and its mRNA in subpopulations of neurons and their corresponding axonal tracts suggests important roles in neural-glial interactions during development and in maturity
    • Silos-Santiago, I.; Yeh, H.J.; Gurrieri, M.A.; Guillerman, R.P.; Li, Y.S.; Wolf, J.; Snider, W.; Deuel, T.F. Localization of pleiotrophin and its mRNA in subpopulations of neurons and their corresponding axonal tracts suggests important roles in neural-glial interactions during development and in maturity. J. Neurobiol. 1996, 31, 283-296.
    • (1996) J. Neurobiol. , vol.31 , pp. 283-296
    • Silos-Santiago, I.1    Yeh, H.J.2    Gurrieri, M.A.3    Guillerman, R.P.4    Li, Y.S.5    Wolf, J.6    Snider, W.7    Deuel, T.F.8
  • 29
    • 0026728088 scopus 로고
    • Cellular distribution of the new growth factor pleiotrophin (HB-GAM) mRNA in developing and adult rat tissues
    • Vanderwinden, J.M.; Mailleux, P.; Schiffmann, S.N.; Vanderhaeghen, J.J. Cellular distribution of the new growth factor pleiotrophin (HB-GAM) mRNA in developing and adult rat tissues. Anat. Embryol. (Berl.) 1992, 186, 387-406.
    • (1992) Anat. Embryol. (Berl.). , vol.186 , pp. 387-406
    • Vanderwinden, J.M.1    Mailleux, P.2    Schiffmann, S.N.3    Vanderhaeghen, J.J.4
  • 30
    • 0032525099 scopus 로고    scopus 로고
    • Upregulation of pleiotrophin gene expression in developing microvasculature, macrophages, and astrocytes after acute ischemic brain injury
    • Yeh, H.J.; He, Y.Y.; Xu, J.; Hsu, C.Y.; Deuel, T.F. Upregulation of pleiotrophin gene expression in developing microvasculature, macrophages, and astrocytes after acute ischemic brain injury. J. Neurosci. 1998, 18, 3699-3707.
    • (1998) J. Neurosci. , vol.18 , pp. 3699-3707
    • Yeh, H.J.1    He, Y.Y.2    Xu, J.3    Hsu, C.Y.4    Deuel, T.F.5
  • 32
    • 0027076643 scopus 로고
    • Pleiotrophin stimulates fibroblasts and endothelial and epithelial cells and is expressed in human cancer
    • Fang, W.; Hartmann, N.; Chow, D.T.; Riegel, A.T.; Wellstein, A. Pleiotrophin stimulates fibroblasts and endothelial and epithelial cells and is expressed in human cancer. J. Biol. Chem. 1992, 267, 25889-25897.
    • (1992) J. Biol. Chem. , vol.267 , pp. 25889-25897
    • Fang, W.1    Hartmann, N.2    Chow, D.T.3    Riegel, A.T.4    Wellstein, A.5
  • 34
    • 0024801855 scopus 로고
    • A novel 17 kD heparin-binding growth factor (HBGF-8) in bovine uterus: Purification and N-terminal amino acid sequence
    • Milner, P.G.; Li, Y.S.; Hoffman, R.M.; Kodner, C.M.; Siegel, N.R.; Deuel, T.F. A novel 17 kD heparin-binding growth factor (HBGF-8) in bovine uterus: purification and N-terminal amino acid sequence. Biochem. Biophys. Res. Commun. 1989, 165, 1096-1103.
    • (1989) Biochem. Biophys. Res. Commun. , vol.165 , pp. 1096-1103
    • Milner, P.G.1    Li, Y.S.2    Hoffman, R.M.3    Kodner, C.M.4    Siegel, N.R.5    Deuel, T.F.6
  • 35
    • 33845188730 scopus 로고    scopus 로고
    • Pleiotrophin disrupts calcium-dependent homophilic cell-cell adhesion and initiates an epithelial-mesenchymal transition
    • Perez-Pinera, P.; Alcantara, S.; Dimitrov, T.; Vega, J.A.; Deuel, T.F. Pleiotrophin disrupts calcium-dependent homophilic cell-cell adhesion and initiates an epithelial-mesenchymal transition. Proc. Natl. Acad. Sci. USA 2006, 103, 17795-17800.
    • (2006) Proc. Natl. Acad. Sci. USA. , vol.103 , pp. 17795-17800
    • Perez-Pinera, P.1    Alcantara, S.2    Dimitrov, T.3    Vega, J.A.4    Deuel, T.F.5
  • 36
    • 0027985605 scopus 로고
    • The potential role of the heparin-binding growth factor pleiotrophin in breast cancer
    • Riegel, A.T.; Wellstein, A. The potential role of the heparin-binding growth factor pleiotrophin in breast cancer. Breast Cancer Res. Treat. 1994, 31, 309-314.
    • (1994) Breast Cancer Res. Treat. , vol.31 , pp. 309-314
    • Riegel, A.T.1    Wellstein, A.2
  • 37
    • 0030904197 scopus 로고    scopus 로고
    • An angiogenic role for the neurokines midkine and pleiotrophin in tumorigenesis
    • Choudhuri, R.; Zhang, H.T.; Donnini, S.; Ziche, M.; Bicknell, R. An angiogenic role for the neurokines midkine and pleiotrophin in tumorigenesis. Cancer Res. 1997, 57, 1814-1819.
    • (1997) Cancer Res , vol.57 , pp. 1814-1819
    • Choudhuri, R.1    Zhang, H.T.2    Donnini, S.3    Ziche, M.4    Bicknell, R.5
  • 38
    • 0030878183 scopus 로고    scopus 로고
    • Human breast cancer growth inhibited in vivo by a dominant negative pleiotrophin mutant
    • Zhang, N.; Zhong, R.; Wang, Z.Y.; Deuel, T.F. Human breast cancer growth inhibited in vivo by a dominant negative pleiotrophin mutant. J. Biol. Chem. 1997, 272, 16733-16736.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16733-16736
    • Zhang, N.1    Zhong, R.2    Wang, Z.Y.3    Deuel, T.F.4
  • 44
    • 79952275697 scopus 로고    scopus 로고
    • 17.5 FDA-approved patient labeling; Bayer Healthcare Pharmaceuticals Inc.: West Haven, CT, USA
    • Nexavar (sorafenib) package insert, 17.5 FDA-approved patient labeling; Bayer Healthcare Pharmaceuticals Inc.: West Haven, CT, USA, 2009.
    • (2009) Nexavar (sorafenib) Package Insert
  • 49
    • 0036830216 scopus 로고    scopus 로고
    • Pleiotrophin/Osteoblast-stimulating factor 1: Dissecting its diverse functions in bone formation
    • Tare, R.S.; Oreffo, R.O.; Clarke, N.M.; Roach, H.I. Pleiotrophin/Osteoblast-stimulating factor 1: dissecting its diverse functions in bone formation. J. Bone Miner. Res. 2002, 17, 2009-2020.
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 2009-2020
    • Tare, R.S.1    Oreffo, R.O.2    Clarke, N.M.3    Roach, H.I.4
  • 50
    • 68949130137 scopus 로고    scopus 로고
    • A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells
    • Vazin, T.; Becker, K.G.; Chen, J.; Spivak, C.E.; Lupica, C.R.; Zhang, Y.; Worden, L.; Freed, W.J. A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells. PLoS One 2009, 4, e6606.
    • (2009) PLoS One , vol.4
    • Vazin, T.1    Becker, K.G.2    Chen, J.3    Spivak, C.E.4    Lupica, C.R.5    Zhang, Y.6    Worden, L.7    Freed, W.J.8
  • 51
    • 33748959850 scopus 로고    scopus 로고
    • Involvement of Pleiotrophin in CNTF-mediated differentiation of the late retinal progenitor cells
    • Roger, J.; Brajeul, V.; Thomasseau, S.; Hienola, A.; Sahel, J.A.; Guillonneau, X.; Goureau, O. Involvement of Pleiotrophin in CNTF-mediated differentiation of the late retinal progenitor cells. Dev. Biol. 2006, 298, 527-539.
    • (2006) Dev. Biol. , vol.298 , pp. 527-539
    • Roger, J.1    Brajeul, V.2    Thomasseau, S.3    Hienola, A.4    Sahel, J.A.5    Guillonneau, X.6    Goureau, O.7
  • 54
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard, J.W. Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer. 2004, 4, 71-78.
    • (2004) Nat. Rev. Cancer. , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 56
    • 41149164902 scopus 로고    scopus 로고
    • The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance
    • Allavena, P.; Sica, A.; Garlanda, C.; Mantovani, A. The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Immunol. Rev. 2008, 222, 155-161.
    • (2008) Immunol. Rev. , vol.222 , pp. 155-161
    • Allavena, P.1    Sica, A.2    Garlanda, C.3    Mantovani, A.4
  • 57
    • 33746926292 scopus 로고    scopus 로고
    • Clodronate-liposome-mediated depletion of tumour-associated macrophages: A new and highly effective antiangiogenic therapy approach
    • Zeisberger, S.M.; Odermatt, B.; Marty, C.; Zehnder-Fjallman, A.H.; Ballmer-Hofer, K.; Schwendener, R.A. Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach. Br. J. Cancer 2006, 95, 272-281.
    • (2006) Br. J. Cancer. , vol.95 , pp. 272-281
    • Zeisberger, S.M.1    Odermatt, B.2    Marty, C.3    Zehnder-Fjallman, A.H.4    Ballmer-Hofer, K.5    Schwendener, R.A.6
  • 58
    • 36549025804 scopus 로고    scopus 로고
    • Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages
    • Lin, E.Y.; Li, J.F.; Bricard, G.; Wang, W.; Deng, Y.; Sellers, R.; Porcelli, S.A.; Pollard, J.W. Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages. Mol. Oncol. 2007, 1, 288-302.
    • (2007) Mol. Oncol. , vol.1 , pp. 288-302
    • Lin, E.Y.1    Li, J.F.2    Bricard, G.3    Wang, W.4    Deng, Y.5    Sellers, R.6    Porcelli, S.A.7    Pollard, J.W.8
  • 59
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek, R.D.; Lewis, C.E.; Whitehouse, R.; Greenall, M.; Clarke, J.; Harris, A.L. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res. 1996, 56, 4625-4629.
    • (1996) Cancer Res , vol.56 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 61
    • 68749109536 scopus 로고    scopus 로고
    • A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth
    • Qian, B.; Deng, Y.; Im, J.H.; Muschel, R.J.; Zou, Y.; Li, J.; Lang, R.A.; Pollard, J.W. A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One 2009, 4, e6562.
    • (2009) PLoS One , vol.4
    • Qian, B.1    Deng, Y.2    Im, J.H.3    Muschel, R.J.4    Zou, Y.5    Li, J.6    Lang, R.A.7    Pollard, J.W.8
  • 64
    • 67651146533 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts
    • Roland, C.L.; Dineen, S.P.; Lynn, K.D.; Sullivan, L.A.; Dellinger, M.T.; Sadegh, L.; Sullivan, J.P.; Shames, D.S.; Brekken, R.A. Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts. Mol. Cancer Ther. 2009, 8, 1761-1771.
    • (2009) Mol. Cancer Ther. , vol.8 , pp. 1761-1771
    • Roland, C.L.1    Dineen, S.P.2    Lynn, K.D.3    Sullivan, L.A.4    Dellinger, M.T.5    Sadegh, L.6    Sullivan, J.P.7    Shames, D.S.8    Brekken, R.A.9
  • 65
    • 70449580340 scopus 로고    scopus 로고
    • Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer
    • Roland, C.L.; Lynn, K.D.; Toombs, J.E.; Dineen, S.P.; Udugamasooriya, D.G.; Brekken, R.A. Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer. PLoS One 2009, 4, e7669.
    • (2009) PLoS One , vol.4
    • Roland, C.L.1    Lynn, K.D.2    Toombs, J.E.3    Dineen, S.P.4    Udugamasooriya, D.G.5    Brekken, R.A.6
  • 66
    • 33751579930 scopus 로고    scopus 로고
    • Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma
    • Salnikov, A.V.; Heldin, N.E.; Stuhr, L.B.; Wiig, H.; Gerber, H.; Reed, R.K.; Rubin, K. Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma. Int. J. Cancer 2006, 119, 2795-2802.
    • (2006) Int. J. Cancer. , vol.119 , pp. 2795-2802
    • Salnikov, A.V.1    Heldin, N.E.2    Stuhr, L.B.3    Wiig, H.4    Gerber, H.5    Reed, R.K.6    Rubin, K.7
  • 71
  • 72
    • 42349094504 scopus 로고    scopus 로고
    • Tumor escape mechanism governed by myeloid-derived suppressor cells
    • Nagaraj, S.; Gabrilovich, D.I. Tumor escape mechanism governed by myeloid-derived suppressor cells. Cancer Res. 2008, 68, 2561-2563.
    • (2008) Cancer Res , vol.68 , pp. 2561-2563
    • Nagaraj, S.1    Gabrilovich, D.I.2
  • 74
    • 0032400862 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo
    • Gabrilovich, D.; Ishida, T.; Oyama, T.; Ran, S.; Kravtsov, V.; Nadaf, S.; Carbone, D. P. Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood 1998, 92, 4150-4166.
    • (1998) Blood , vol.92 , pp. 4150-4166
    • Gabrilovich, D.1    Ishida, T.2    Oyama, T.3    Ran, S.4    Kravtsov, V.5    Nadaf, S.6    Carbone, D.P.7
  • 78
    • 33747602354 scopus 로고    scopus 로고
    • Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis
    • Nozawa, H.; Chiu, C.; Hanahan, D. Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis. Proc. Natl. Acad. Sci. USA 2006, 103, 12493-12498.
    • (2006) Proc. Natl. Acad. Sci. USA. , vol.103 , pp. 12493-12498
    • Nozawa, H.1    Chiu, C.2    Hanahan, D.3
  • 80
    • 2342475284 scopus 로고    scopus 로고
    • Vascular endothelial growth factor VEGF189 induces human neutrophil chemotaxis in extravascular tissue via an autocrine amplification mechanism
    • Ancelin, M.; Chollet-Martin, S.; Herve, M.A.; Legrand, C.; El Benna, J.; Perrot-Applanat, M. Vascular endothelial growth factor VEGF189 induces human neutrophil chemotaxis in extravascular tissue via an autocrine amplification mechanism. Lab. Invest. 2004, 84, 502-512.
    • (2004) Lab. Invest. , vol.84 , pp. 502-512
    • Ancelin, M.1    Chollet-Martin, S.2    Herve, M.A.3    Legrand, C.4    El Benna, J.5    Perrot-Applanat, M.6
  • 81
    • 41649116240 scopus 로고    scopus 로고
    • Plasticity in tumor-promoting inflammation: Impairment of macrophage recruitment evokes a compensatory neutrophil response
    • Pahler, J.C.; Tazzyman, S.; Erez, N.; Chen, Y.Y.; Murdoch, C.; Nozawa, H.; Lewis, C.E.; Hanahan, D. Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response. Neoplasia 2008, 10, 329-340.
    • (2008) Neoplasia , vol.10 , pp. 329-340
    • Pahler, J.C.1    Tazzyman, S.2    Erez, N.3    Chen, Y.Y.4    Murdoch, C.5    Nozawa, H.6    Lewis, C.E.7    Hanahan, D.8
  • 83
  • 84
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendritic-cell defects
    • Gabrilovich, D. Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat. Rev. Immunol. 2004, 4, 941-952.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 941-952
    • Gabrilovich, D.1
  • 85
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibitis the functional maturation of dendritic cells
    • Gabrilovich, D.I.; Chen, H.L.; Girgis, K.R.; Cunningham, H.T.; Meny, G.M.; Nadaf, S.; Kavanaugh, D.; Carbone, D.P. Production of vascular endothelial growth factor by human tumors inhibitis the functional maturation of dendritic cells. Nat. Med. 1996, 2, 1096-1103.
    • (1996) Nat. Med. , vol.2 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3    Cunningham, H.T.4    Meny, G.M.5    Nadaf, S.6    Kavanaugh, D.7    Carbone, D.P.8
  • 86
    • 34547106845 scopus 로고    scopus 로고
    • Distinct roles of VEGFR-1 and VEGFR-2 in the aberrant hematopoiesis associated with elevated levels of VEGF
    • Huang, Y.; Chen, X.; Dikov, M.M.; Novitskiy, S.V.; Mosse, C.A.; Yang, L.; Carbone, D.P. Distinct roles of VEGFR-1 and VEGFR-2 in the aberrant hematopoiesis associated with elevated levels of VEGF. Blood 2007, 110, 624-631.
    • (2007) Blood , vol.110 , pp. 624-631
    • Huang, Y.1    Chen, X.2    Dikov, M.M.3    Novitskiy, S.V.4    Mosse, C.A.5    Yang, L.6    Carbone, D.P.7
  • 87
    • 0031892785 scopus 로고    scopus 로고
    • Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells
    • Oyama, T.; Ran, S.; Ishida, T.; Nadaf, S.; Kerr, L.; Carbone, D. P.; Gabrilovich, D. I. Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells. J. Immunol. 1998, 160, 1224-1232.
    • (1998) J. Immunol. , vol.160 , pp. 1224-1232
    • Oyama, T.1    Ran, S.2    Ishida, T.3    Nadaf, S.4    Kerr, L.5    Carbone, D.P.6    Gabrilovich, D.I.7
  • 88
    • 34248191292 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits the function of human mature dendritic cells mediated by VEGF receptor-2
    • Mimura, K.; Kono, K.; Takahashi, A.; Kawaguchi, Y.; Fujii, H. Vascular endothelial growth factor inhibits the function of human mature dendritic cells mediated by VEGF receptor-2. Cancer Immunol. Immunother. 2007, 56, 761-770.
    • (2007) Cancer Immunol. Immunother. , vol.56 , pp. 761-770
    • Mimura, K.1    Kono, K.2    Takahashi, A.3    Kawaguchi, Y.4    Fujii, H.5
  • 91
    • 34548125294 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses
    • Fricke, I.; Mirza, N.; Dupont, J.; Lockhart, C.; Jackson, A.; Lee, J.H.; Sosman, J.A.; Gabrilovich, D.I. Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses. Clin. Cancer Res. 2007, 13, 4840-4848.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 4840-4848
    • Fricke, I.1    Mirza, N.2    Dupont, J.3    Lockhart, C.4    Jackson, A.5    Lee, J.H.6    Sosman, J.A.7    Gabrilovich, D.I.8
  • 93
    • 37649005055 scopus 로고    scopus 로고
    • Defective differentiation of myeloid and plasmacytoid dendritic cells in advanced cancer patients is not normalized by tyrosine kinase inhibition of the vascular endothelial growth factor receptor
    • van Cruijsen, H.; Hoekman, K.; Stam, A. G.; van den Eertwegh, A. J.; Kuenen, B. C.; Scheper, R. J.; Giaccone, G.; de Gruijl, T. D. Defective differentiation of myeloid and plasmacytoid dendritic cells in advanced cancer patients is not normalized by tyrosine kinase inhibition of the vascular endothelial growth factor receptor. Clin. Dev. Immunol. 2007, 2007, 17315.
    • (2007) Clin. Dev. Immunol. , vol.2007 , pp. 17315
    • van Cruijsen, H.1    Hoekman, K.2    Stam, A.G.3    van den Eertwegh, A.J.4    Kuenen, B.C.5    Scheper, R.J.6    Giaccone, G.7    de Gruijl, T.D.8
  • 94
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
    • Dieckmann, D.; Plottner, H.; Berchtold, S.; Berger, T.; Schuler, G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J. Exp. Med. 2001, 193, 1303-1310.
    • (2001) J. Exp. Med. , vol.193 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 95
    • 34547210257 scopus 로고    scopus 로고
    • Intratumoral FOXP3 expression in infiltrating breast carcinoma: Its association with clinicopathologic parameters and angiogenesis
    • Gupta, S.; Joshi, K.; Wig, J.D.; Arora, S.K. Intratumoral FOXP3 expression in infiltrating breast carcinoma: Its association with clinicopathologic parameters and angiogenesis. Acta Oncol. 2007, 46, 792-797.
    • (2007) Acta Oncol , vol.46 , pp. 792-797
    • Gupta, S.1    Joshi, K.2    Wig, J.D.3    Arora, S.K.4
  • 97
    • 65549112641 scopus 로고    scopus 로고
    • Dynamic behavior and function of Foxp3+ regulatory T cells in tumor bearing host
    • Qin, F.X. Dynamic behavior and function of Foxp3+ regulatory T cells in tumor bearing host. Cell Mol. Immunol. 2009, 6, 3-13.
    • (2009) Cell Mol. Immunol. , vol.6 , pp. 3-13
    • Qin, F.X.1
  • 98
    • 43249097073 scopus 로고    scopus 로고
    • CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells
    • Perruche, S.; Zhang, P.; Liu, Y.; Saas, P.; Bluestone, J.A.; Chen, W. CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells. Nat. Med. 2008, 14, 528-535.
    • (2008) Nat. Med. , vol.14 , pp. 528-535
    • Perruche, S.1    Zhang, P.2    Liu, Y.3    Saas, P.4    Bluestone, J.A.5    Chen, W.6
  • 99
    • 73349110096 scopus 로고    scopus 로고
    • The role of antiangiogenesis therapy: Bevacizumab and beyond
    • Cortes-Funes, H. The role of antiangiogenesis therapy: bevacizumab and beyond. Clin. Transl. Oncol. 2009, 11, 349-355.
    • (2009) Clin. Transl. Oncol. , vol.11 , pp. 349-355
    • Cortes-Funes, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.