Pleiotrophin induces nitric oxide dependent migration of endothelial progenitor cells

Journal of Cellular Physiology

Volumn 215, Issue 2, 2008, Pages 366-373

  Heiss, Christian ^a   Wong, Maelene L ^a   Block, Vanessa I ^a   Lao, David ^a   Real, Wendy May ^a   Yeghiazarians, Yerem ^a   Lee, Randall J ^a   Springer, Matthew L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4,5 DIAMINOFLUORESCEIN DIACETATE; N(G) METHYLARGININE; N(G) NITROARGININE; NITRIC OXIDE; PLEIOTROPHIN; STROMAL CELL DERIVED FACTOR 1ALPHA; SYNDECAN 3; VASCULOTROPIN; WORTMANNIN; ANGIOGENIC FACTOR; CARRIER PROTEIN; CYTOKINE; NITRIC OXIDE SYNTHASE; STROMAL CELL DERIVED FACTOR 1; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; CORONARY ARTERY; ENDOTHELIUM CELL; GLIOBLASTOMA; HUMAN; HUMAN CELL; NORMAL HUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; STEM CELL; TUMOR CELL; UMBILICAL VEIN; ADULT; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

ADULT; ANGIOGENESIS INDUCING AGENTS; CARRIER PROTEINS; CELL PROLIFERATION; CELLS, CULTURED; CHEMOKINE CXCL12; CHEMOTAXIS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; STEM CELLS; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 40949145679     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21313     Document Type: Article

References (41)

1. Asahara T, Murohara T, Sullivan A, Silver M, van der ZR, Li T, Witzenbichler B, Schatteman G, Isner JM. 1997. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275:964-967.
2. Asahara T, Takahashi T, Masuda H, Kalka C, Chen D, Iwaguro H, Inai Y, Silver M, Isner JM. 1999. VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J 18:3964-3972.
3. Bussolati B, Dunk C, Grohman M, Kontos CD, Mason J, Ahmed A. 2001. Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide. Am J Pathol 159:993-1008.
4. Christman KL, Sievers RE, Fang Q, Colley KJ, Lee RJ. 2003. Myocardial ischemia induced upregulation of pleiotrophin gene. p. 393a.
5. Christman KL, Fang Q, Kim AJ, Sievers RE, Fok HH, Candia AF, Colley KJ, Herradon G, Ezquerra L, Deuel TF, Lee RJ. 2005. Pleiotrophin induces formation of functional neovasculature in vivo. Biochem Biophys Res Commun 332:1146-1152.
6. Deuel TF, Zhang N, Yeh HJ, Silos-Santiago I, Wang ZY. 2002. Pleiotrophin: A cytokine with diverse functions and a novel signaling pathway. Arch Biochem Biophys 397:162-171.
7. Dimmeler S, Zeiher AM, Schneider MD. 2005. Unchain my heart: The scientific foundations of cardiac repair. J Clin Invest 115:572-583.
8. Falk W, Goodwin RH Jr, Leonard EJ. 1980. A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration. J Immunol Methods 33:239-247.
9. Fang W, Hartmann N, Chow DT, Riegel AT, Wellstein A. 1992. Pleiotrophin stimulates fibroblasts and endothelial and epithelial cells and is expressed in human cancer. J Biol Chem 267:25889-25897.
10. Heiss C, Keymel S, Niesler U, Ziemann J, Kelm M, Kalka C. 2005. Impaired progenitor cell activity in age-related endothelial dysfunction. J Am Coll Cardiol 45:1441-1448.
11. Heiss C, Lauer T, Dejam A, Kieinbongard P, Hamada S, Rassaf T, Matern S, Feelisch M, Kelm M. 2006. Plasma nitroso compounds are decreased in patients with endothelial dysfunction. J Am Coll Cardiol 47:573-579.
12. Hill JM, Zalos G, Halcox JP, Schenke WH, Waclawiw MA, Quyyumi AA, Finkel T. 2003. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 348:593-600.
13. Hoetzer GL, Irmiger HM, Keith RS, Westbrook KM, DeSouza CA. 2005. Endothelial nitric oxide synthase inhibition does not alter endothelial progenitor cell colony forming capacity or migratory activity. J Cardiovasc Pharmacol 46:387-389.
14. Hur J, Yoon CH, Kim HS, Choi JH, Kang HJ, Hwang KK, Oh BH, Lee MM, Park YB. 2004. Characterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesis. Arterioscler Thromb Vasc Biol 24:288-293.
15. Isenberg JS, Ridnour LA, Thomas DD, Wink DA, Roberts DD, Espey MG. 2006. Guanylyl cyclase-dependent chemotaxis of endothelial cells in response to nitric oxide gradients. Free Radic Biol Med 40:1028-1033.
16. Jackson KA, Majka SM, Wang H, Pocius J, Hartley CJ, Majesky MW, Entman ML, Michael LH, Hirschi KK. Goodell MA. 2001. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 107:1395-1402.
17. Jin DK, Shido K, Kopp HG, Petit I, Shmelkov SV, Young LM, Hooper AT, Amano H, Avecilla ST, Heissig B, Hattori K, Zhang F, Hicklin DJ, Wu Y, Zhu Z, Dunn A, Salari H, Werb Z, Hackett NR, Crystal RG, Lyden D, Rafii S. 2006. Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. Nat Med 12:557-567.
18. Kalka C, Masuda H, Takahashi T, Kalka-Moll WM, Silver M, Kearney M, Li T, Isner JM, Asahara T. 2000. Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci USA 97:3422-3427.
19. Kojima H, Nakatsubo N, Kikuchi K, Kawahara S, Kirino Y, Nagoshi H, Hirata Y, Nagano T. 1998. Detection and imaging of nitric oxide with novel fluorescent indicators: Diaminofluoresceins. Anal Chem 70:2446-2453.
20. Li YS, Milner PG, Chauhan AK, Watson MA, Hoffman RM, Kodner CM, Milbrandt J, Deuel TF. 1990. Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity. Science 250:1690-1694.
21. Lu KV, Jong KA, Kim GY, Singh J, Dia EQ, Yoshimoto K, Wang MY, Cloughesy TF, Nelson SF, Mischel PS. 2005. Differential induction of glioblastoma migration and growth by two forms of pleiotrophin. J Biol Chem 280:26953-26964.
22. Milner PG, Li YS, Hoffman RM, Kodner CM, Siegel NR, Deuel TF. 1989. A novel 17 kD heparin-binding growth factor (HBGF-8) in bovine uterus: Purification and N-terminal amino acid sequence. Biochem Biophys Res Commun 165:1096-1103.
23. Nakul-Aquaronne D, Bayle J, Frelin C. 2003. Coexpression of endothelial markers and CD14 by cytokine mobilized CD34+ cells under angiogenic stimulation. Cardiovasc Res 57:816-823.
24. Ozuyaman B, Ebner P, Niesler U, Ziemann J, Kleinbongard P, Jax T, Godecke A, Kelm M, Kalka C. 2005. Nitric oxide differentially regulates proliferation and mobilization of endothelial progenitor cells but not of hematopoietic stem cells. Thromb Haemost 94:770-772.
25. Pariser H, Herradon G, Ezquerra L, Perez-Pinera P, Deuel TF. 2005. Pleiotrophin regulates serine phosphorylation and the cellular distribution of {beta}·adducin through activation of protein kinase C. Proc Natl Acad Sci 102:12407-12412.
26. Petersen W, Rafii M. 2001. Immunolocalization of the angiogenetic factor pleiotrophin (PTN) in the growth plate of mice. Arch Orthop Trauma Surg 121:414-416.
27. Pietraforte D, Mallozzi C, Scorza G, Minetti M. 1995. Role of thiols in the targeting of S-nitroso thiols to red blood cells. Biochemistry 34:7177-7185.
28. Rauvala H. 1989. An 18-kD heparin-binding protein of developing brain that is distinct from fibroblast growth factors. EMBO J 8:2933-2941.
29. Rehman J, Li J, Orschell CM, March KL. 2003. Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation 107:1164-1169.
30. Roy H, Bhardwaj S, Yla-Herttuala S. 2006. Biology of vascular endothelial growth factors. FEBS Lett 580:2879-2887.
31. Ruiz de Almodovar C, Luttun A, Carmeliet P. 2006. An SDF-1 Trap for myeloid cells stimulates angiogenesis. Cell 124:18-21.
32. Sharifi BG, Zeng Z, Wang L, Song L, Chen H, Qin M, Sierra-Honigmann MR, Wachsmann-Hogiu S, Shah PK. 2006. Pleiotrophin induces trans differentiation of monocytes into functional endothelial cells. Arterioscler Thromb Vasc Biol 26:1273-1280.
33. Souttou B, Raulais D, Vigny M. 2001. Pleiotrophin induces angiogenesis: Involvement of the phosphoinositide-3 kinase but not the nitric oxide synthase pathways. J Cell Physiol 187:59-64.
34. Springer ML. 2006. A balancing act: Therapeutic approaches for the modulation of angiogenesis. Curr Opin Investig Drugs 7:243-250.
35. Springer ML, Chen AS, Kraft PE, Bednarski M, Blau HM. 1998. VEGF gene delivery to muscle: Potential role for vasculogenes is in adults. Mol Cell 2:549-558.
36. Springer ML, Brazelton TR, Blau HM. 2001. Not the usual suspects: The unexpected sources of tissue regeneration. J Clin Invest 107:1355-1356.
37. Springer ML, Ozawa CR, Banfi A, Kraft PE, Ip TK, Brazelton TR, Blau HM. 2003. Localized arteriole formation directly adjacent to the site of VEGF-induced angiogenesis in muscle. Mol Ther 7:441-449.
38. Urbich C, Heeschen C, Aicher A, Dernbach E, Zeiher AM, Dimmeler S. 2003. Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells. Circulation 108:2511-2516.
39. Vasa M, Fichtischerer S, Aicher A, Adler K, Urbich C, Martin H, Zeiher AM, Dimmeler S. 2001. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 89:E1-E7.
40. Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, Link A, Bohm M, Nickenig G. 2005. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 353:999-1007.
41. Yeh HJ, He YY, Xu J, Hsu CY, Deuel TF. 1998. Upregulation of pleiotrophin gene expression in developing microvasculature, macrophages, and astrocytes after acute ischemic brain injury. J Neurosci 18:3699-3707.