메뉴 건너뛰기




Volumn 1, Issue 2, 2010, Pages 99-102

Transcription and replication: Breaking the rules of the road causes genomic instability

Author keywords

DNA replication; Genomic instability; R loops; Transcription associated recombination

Indexed keywords

BACTERIAL DNA; CELL DNA; DNA DIRECTED RNA POLYMERASE; DNA POLYMERASE; RIBOSOME DNA; RIBOSOME RNA; RNA POLYMERASE II;

EID: 79952257414     PISSN: 21541264     EISSN: 21541272     Source Type: Journal    
DOI: 10.4161/trns.1.2.12665     Document Type: Article
Times cited : (29)

References (42)
  • 1
    • 33947432388 scopus 로고    scopus 로고
    • Replication Fork Stalling at Natural Impediments
    • Mirkin EV, Mirkin SM. Replication Fork Stalling at Natural Impediments. Microbiol Mol Biol Rev 2007; 71:13-35.
    • (2007) Microbiol Mol Biol Rev , vol.71 , pp. 13-35
    • Mirkin, E.V.1    Mirkin, S.M.2
  • 2
    • 66749175352 scopus 로고    scopus 로고
    • Transcription-associated recombination in eukaryotes: Link between transcription, replication and recombination
    • Gottipati P, Helleday T. Transcription-associated recombination in eukaryotes: link between transcription, replication and recombination. Mutagenesis 2009; 24:203-10.
    • (2009) Mutagenesis , vol.24 , pp. 203-210
    • Gottipati, P.1    Helleday, T.2
  • 3
    • 0028908039 scopus 로고
    • Head-on collision between a DNA replication apparatus and RNA polymerase transcription complex
    • Liu B, Alberts BM. Head-on collision between a DNA replication apparatus and RNA polymerase transcription complex. Science 1995; 267:1131-7.
    • (1995) Science , vol.267 , pp. 1131-1137
    • Liu, B.1    Alberts, B.M.2
  • 4
    • 0033954246 scopus 로고    scopus 로고
    • Replication fork pausing and recombination or "gimme a break."
    • Rothstein R, Michel B, Gangloff S. Replication fork pausing and recombination or "gimme a break." Genes Dev 2000; 14:1-10.
    • (2000) Genes Dev , vol.14 , pp. 1-10
    • Rothstein, R.1    Michel, B.2    Gangloff, S.3
  • 5
    • 0026688590 scopus 로고
    • DNA transcription and repressor binding affect deletion formation in Escherichia coli plasmids
    • Vilette D, Uzest M, Ehrlich SD, Michel B. DNA transcription and repressor binding affect deletion formation in Escherichia coli plasmids. EMBO J 1992; 11:3629-34.
    • (1992) EMBO J , vol.11 , pp. 3629-3634
    • Vilette, D.1    Uzest, M.2    Ehrlich, S.D.3    Michel, B.4
  • 6
    • 0036469913 scopus 로고    scopus 로고
    • The connection between transcription and genomic instability
    • Aguilera A. The connection between transcription and genomic instability. EMBO J 2001; 21:195-201.
    • (2001) EMBO J , vol.21 , pp. 195-201
    • Aguilera, A.1
  • 7
    • 0029740114 scopus 로고    scopus 로고
    • DNA replication fork pause sites dependent on transcription
    • Deshpande AM, Newlon CS. DNA replication fork pause sites dependent on transcription. Science 1996; 272:1030-3.
    • (1996) Science , vol.272 , pp. 1030-1033
    • Deshpande, A.M.1    Newlon, C.S.2
  • 8
    • 57649129186 scopus 로고    scopus 로고
    • The replisome uses mRNA as a primer after colliding with RNA polymerase
    • Pomerantz RT, O'Donnell M. The replisome uses mRNA as a primer after colliding with RNA polymerase. Nature 2008; 456:762-6.
    • (2008) Nature , vol.456 , pp. 762-766
    • Pomerantz, R.T.1    O'Donnell, M.2
  • 9
    • 75749150810 scopus 로고    scopus 로고
    • Direct restart of a replication fork stalled by a head-on RNA polymerase
    • Pomerantz RT, O'Donnell M. Direct restart of a replication fork stalled by a head-on RNA polymerase. Science 2010; 327:590-2.
    • (2010) Science , vol.327 , pp. 590-592
    • Pomerantz, R.T.1    O'Donnell, M.2
  • 10
    • 34249941504 scopus 로고    scopus 로고
    • Avoiding and resolving conflicts between DNA replication and transcription
    • Rudolph CJ, Dhillon P, Moore T, Lloyd RG. Avoiding and resolving conflicts between DNA replication and transcription. DNA Repair 2007; 6:981-93.
    • (2007) DNA Repair , vol.6 , pp. 981-993
    • Rudolph, C.J.1    Dhillon, P.2    Moore, T.3    Lloyd, R.G.4
  • 11
    • 0024276903 scopus 로고
    • When polymerases collide: Replication and the transcriptional organization of the E. coli chromosome
    • Brewer BJ. When polymerases collide: replication and the transcriptional organization of the E. coli chromosome. Cell 1988; 53:679-86.
    • (1988) Cell , vol.53 , pp. 679-686
    • Brewer, B.J.1
  • 12
    • 34248394295 scopus 로고    scopus 로고
    • Genomewide coorientation of replication and transcription reduces adverse effects on replication in Bacillus subtilis
    • Wang JD, Berkmen MB, Grossman AD. Genomewide coorientation of replication and transcription reduces adverse effects on replication in Bacillus subtilis. Proc Natl Acad Sci USA 2007; 104:5608-13.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5608-5613
    • Wang, J.D.1    Berkmen, M.B.2    Grossman, A.D.3
  • 13
    • 0024977417 scopus 로고
    • Elevated recombination rates in transcriptionally active DNA
    • Thomas BJ, Rothstein R. Elevated recombination rates in transcriptionally active DNA. Cell 1989; 56:619-30.
    • (1989) Cell , vol.56 , pp. 619-630
    • Thomas, B.J.1    Rothstein, R.2
  • 14
    • 0025140542 scopus 로고
    • Transcription stimulates homologous recombination in mammalian cells
    • Nickoloff JA, Reynolds RJ. Transcription stimulates homologous recombination in mammalian cells. Mol Cell Biol 1990; 10:4837-45.
    • (1990) Mol Cell Biol , vol.10 , pp. 4837-4845
    • Nickoloff, J.A.1    Reynolds, R.J.2
  • 15
    • 39449096135 scopus 로고    scopus 로고
    • Genome instability: A mechanistic view of its causes and consequences
    • Aguilera A, Gomez-Gonzalez B. Genome instability: a mechanistic view of its causes and consequences. Nat Rev Genet 2008; 9:204-17.
    • (2008) Nat Rev Genet , vol.9 , pp. 204-217
    • Aguilera, A.1    Gomez-Gonzalez, B.2
  • 17
    • 17144426028 scopus 로고    scopus 로고
    • Impairment of replication fork progression mediates RNA polII transcription-associated recombination
    • Prado F, Aguilera A. Impairment of replication fork progression mediates RNA polII transcription-associated recombination. EMBO J 2005; 24:1267-76.
    • (2005) EMBO J , vol.24 , pp. 1267-1276
    • Prado, F.1    Aguilera, A.2
  • 18
    • 0038046165 scopus 로고    scopus 로고
    • Transcriptiondependent recombination and the role of fork collision in yeast rDNA
    • Takeuchi Y, Horiuchi T, Kobayashi T. Transcriptiondependent recombination and the role of fork collision in yeast rDNA. Genes Dev 2003; 17:1497-506.
    • (2003) Genes Dev , vol.17 , pp. 1497-1506
    • Takeuchi, Y.1    Horiuchi, T.2    Kobayashi, T.3
  • 19
    • 67449113551 scopus 로고    scopus 로고
    • Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae
    • Azvolinsky A, Giresi PG, Lieb JD, Zakian VA. Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae. Mol Cell 2009; 34:722-34.
    • (2009) Mol Cell , vol.34 , pp. 722-734
    • Azvolinsky, A.1    Giresi, P.G.2    Lieb, J.D.3    Zakian, V.A.4
  • 20
    • 34249935010 scopus 로고    scopus 로고
    • Maintenance of fork integrity at damaged DNA and natural pause sites
    • Tourriere H, Pasero P. Maintenance of fork integrity at damaged DNA and natural pause sites. DNA Repair 2007; 6:900-13.
    • (2007) DNA Repair , vol.6 , pp. 900-913
    • Tourriere, H.1    Pasero, P.2
  • 21
    • 37549026516 scopus 로고    scopus 로고
    • Transcription-associated recombination is dependent on replication in mammalian cells
    • Gottipati P, Cassel TN, Savolainen L, Helleday T. Transcription-associated recombination is dependent on replication in mammalian cells. Mol Cell Biol 2008; 28:154-64.
    • (2008) Mol Cell Biol , vol.28 , pp. 154-164
    • Gottipati, P.1    Cassel, T.N.2    Savolainen, L.3    Helleday, T.4
  • 22
    • 59649116359 scopus 로고    scopus 로고
    • Transcription-associated recombination is independent of XRCC2 and mechanistically separate from homology-directed DNA double-strand break repair
    • Savolainen L, Helleday T. Transcription-associated recombination is independent of XRCC2 and mechanistically separate from homology-directed DNA double-strand break repair. Nucl Acids Res 2009; 37:405-12.
    • (2009) Nucl Acids Res , vol.37 , pp. 405-412
    • Savolainen, L.1    Helleday, T.2
  • 23
    • 0030133624 scopus 로고    scopus 로고
    • A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities
    • Kobayashi T, Horiuchi T. A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities. Genes Cells 1996; 1:465-74.
    • (1996) Genes Cells , vol.1 , pp. 465-474
    • Kobayashi, T.1    Horiuchi, T.2
  • 24
    • 0036791653 scopus 로고    scopus 로고
    • Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus
    • Pasero P, Bensimon A, Schwob E. Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus. Genes Dev 2002; 16:2479-84.
    • (2002) Genes Dev , vol.16 , pp. 2479-2484
    • Pasero, P.1    Bensimon, A.2    Schwob, E.3
  • 25
    • 0343488591 scopus 로고    scopus 로고
    • Termination of mammalian rDNA replication: Polar arrest of replication fork movement by transcription termination factor TTF-I
    • Gerber JK, Gogel E, Berger C, Wallisch M, Muller F, Grummt I, et al. Termination of mammalian rDNA replication: polar arrest of replication fork movement by transcription termination factor TTF-I. Cell 1997; 90:559-67.
    • (1997) Cell , vol.90 , pp. 559-567
    • Gerber, J.K.1    Gogel, E.2    Berger, C.3    Wallisch, M.4    Muller, F.5    Grummt, I.6
  • 26
  • 28
    • 9644302474 scopus 로고    scopus 로고
    • Recruitment of transcription complexes to the {beta}-globin gene locus in vivo and in vitro
    • Vieira KF, Levings PP, Hill MA, Crusselle VJ, Kang S-HL, Engel JD, et al. Recruitment of transcription complexes to the {beta}-globin gene locus in vivo and in vitro. J Biol Chem 2004; 279:50350-7.
    • (2004) J Biol Chem , vol.279 , pp. 50350-50357
    • Vieira, K.F.1    Levings, P.P.2    Hill, M.A.3    Crusselle, V.J.4    Kang, S.-H.L.5    Engel, J.D.6
  • 29
    • 0033546210 scopus 로고    scopus 로고
    • The organization of replication and transcription
    • Cook PR. The organization of replication and transcription. Science 1999; 284:1790-5.
    • (1999) Science , vol.284 , pp. 1790-1795
    • Cook, P.R.1
  • 30
    • 33745239698 scopus 로고    scopus 로고
    • Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories
    • Kitamura E, Blow JJ, Tanaka TU. Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories. Cell 2006; 125:1297-308.
    • (2006) Cell , vol.125 , pp. 1297-1308
    • Kitamura, E.1    Blow, J.J.2    Tanaka, T.U.3
  • 31
    • 33645052194 scopus 로고    scopus 로고
    • Growth inhibition mediated by excess negative supercoiling: The interplay between transcription elongation, R-loop formation and DNA topology
    • Drolet M. Growth inhibition mediated by excess negative supercoiling: the interplay between transcription elongation, R-loop formation and DNA topology. Mol Microbiol 2006; 59:723-30.
    • (2006) Mol Microbiol , vol.59 , pp. 723-730
    • Drolet, M.1
  • 32
    • 23744455164 scopus 로고    scopus 로고
    • Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability
    • Li X, Manley JL. Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability. Cell 2005; 122:365-78.
    • (2005) Cell , vol.122 , pp. 365-378
    • Li, X.1    Manley, J.L.2
  • 33
    • 0037650190 scopus 로고    scopus 로고
    • R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
    • Yu K, Chedin F, Hsieh CL, Wilson TE, Lieber MR. R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nat Immunol 2003; 4:442-51.
    • (2003) Nat Immunol , vol.4 , pp. 442-451
    • Yu, K.1    Chedin, F.2    Hsieh, C.L.3    Wilson, T.E.4    Lieber, M.R.5
  • 34
    • 0141819093 scopus 로고    scopus 로고
    • Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination
    • Huertas P, Aguilera A. Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination. Mol Cell 2003; 12:711-21.
    • (2003) Mol Cell , vol.12 , pp. 711-721
    • Huertas, P.1    Aguilera, A.2
  • 35
    • 33746093492 scopus 로고    scopus 로고
    • Cotranscriptional processes and their influence on genome stability
    • Li X, Manley JL. Cotranscriptional processes and their influence on genome stability. Genes Dev 2006; 20:1838-47.
    • (2006) Genes Dev , vol.20 , pp. 1838-1847
    • Li, X.1    Manley, J.L.2
  • 36
    • 70349335582 scopus 로고    scopus 로고
    • The S-phase checkpoint is required to respond to R-loops accumulated in THO mutants
    • Gomez-Gonzalez B, Felipe-Abrio I, Aguilera A. The S-phase checkpoint is required to respond to R-loops accumulated in THO mutants. Mol Cell Biol 2009; 29:5203-13.
    • (2009) Mol Cell Biol , vol.29 , pp. 5203-5213
    • Gomez-Gonzalez, B.1    Felipe-Abrio, I.2    Aguilera, A.3
  • 37
    • 33749609648 scopus 로고    scopus 로고
    • A hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination
    • Huertas P, Garcia-Rubio ML, Wellinger RE, Luna R, Aguilera A. A hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination. Mol Cell Biol 2006.
    • (2006) Mol Cell Biol
    • Huertas, P.1    Garcia-Rubio, M.L.2    Wellinger, R.E.3    Luna, R.4    Aguilera, A.5
  • 38
    • 70449522304 scopus 로고    scopus 로고
    • Topoisomerase 1 suppresses replication stress and genomic instability by preventing interference between replication and transcription
    • Tuduri S, Crabbe L, Conti C, Tourriere H, Holtgreve-Grez H, Jauch A, et al. Topoisomerase 1 suppresses replication stress and genomic instability by preventing interference between replication and transcription. Nat Cell Biol 2009; 11:1315-24.
    • (2009) Nat Cell Biol , vol.11 , pp. 1315-1324
    • Tuduri, S.1    Crabbe, L.2    Conti, C.3    Tourriere, H.4    Holtgreve-Grez, H.5    Jauch, A.6
  • 39
    • 15844415445 scopus 로고    scopus 로고
    • Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I
    • Rossi F, Labourier E, Forne T, Divita G, Derancourt J, Riou JF, et al. Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I. Nature 1996; 381:80-2.
    • (1996) Nature , vol.381 , pp. 80-82
    • Rossi, F.1    Labourier, E.2    Forne, T.3    Divita, G.4    Derancourt, J.5    Riou, J.F.6
  • 40
    • 67651119997 scopus 로고    scopus 로고
    • A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability
    • Paulsen RD, Soni DV, Wollman R, Hahn AT, Yee MC, Guan A, et al. A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability. Mol Cell 2009; 35:228-39.
    • (2009) Mol Cell , vol.35 , pp. 228-239
    • Paulsen, R.D.1    Soni, D.V.2    Wollman, R.3    Hahn, A.T.4    Yee, M.C.5    Guan, A.6
  • 41
    • 37549036739 scopus 로고    scopus 로고
    • Mechanism of R-loop formation at immunoglobulin class switch sequences
    • Roy D, Yu K, Lieber MR. Mechanism of R-loop formation at immunoglobulin class switch sequences. Mol Cell Biol 2008; 28:50-60.
    • (2008) Mol Cell Biol , vol.28 , pp. 50-60
    • Roy, D.1    Yu, K.2    Lieber, M.R.3
  • 42
    • 40449120350 scopus 로고    scopus 로고
    • An oncogene- induced DNA damage model for cancer development
    • Halazonetis TD, Gorgoulis VG, Bartek J. An oncogene- induced DNA damage model for cancer development. Science 2008; 319:1352-5.
    • (2008) Science , vol.319 , pp. 1352-1355
    • Halazonetis, T.D.1    Gorgoulis, V.G.2    Bartek, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.